In:
Natural Product Communications, SAGE Publications, Vol. 11, No. 5 ( 2016-05), p. 1934578X1601100-
Abstract:
One new flavonol diglycoside, 4′,5-dihydroxy-3,3′,7-trimethoxyflavone 4′- O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (1), and two known compounds (2–3) were isolated from the methanol extract of Anoectochilus annamensis Aver. aerial parts. The effects were evaluated of all isolated compounds (1–3) on LPS-induced production of the inflammatory mediator nitric oxide (NO) by RAW264.7 cells. 4′,5-Dihydroxy-3,3′,7-trimethoxyflavone (2) was the most active while the addition of a rutinoside at C-4′ (compound 1) decreased the inhibitory activity. This is the first report on the chemical composition and biological activity of A annamensis.
Type of Medium:
Online Resource
ISSN:
1934-578X
,
1555-9475
DOI:
10.1177/1934578X1601100514
Language:
English
Publisher:
SAGE Publications
Publication Date:
2016
detail.hit.zdb_id:
2430442-6
SSG:
15,3
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