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  • SAGE Publications  (7)
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  • SAGE Publications  (7)
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  • 1
    Online Resource
    Online Resource
    Prolactin Binds to Human Endometrial Fibroblasts and Inhibits Mitogenicity of an Endometrial Carcinoma Extract
    SAGE Publications ; 1993
    In:  Experimental Biology and Medicine Vol. 203, No. 2 ( 1993-06-01), p. 117-122
    Details
    In: Experimental Biology and Medicine, SAGE Publications, Vol. 203, No. 2 ( 1993-06-01), p. 117-122
    Type of Medium: Online Resource
    ISSN: 1535-3702 , 1535-3699
    URL: Article
    DOI: 10.3181/00379727-203-43581aa
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1993
    detail.hit.zdb_id: 2020856-X
    SSG: 12
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Autologous Peripheral Stem-Cell Transplantation after Intensive Chemotherapy in a Case of CD30 (Ki-1)-Positive Anaplastic Large-Cell Lymphoma
    SAGE Publications ; 2001
    In:  Journal of International Medical Research Vol. 29, No. 5 ( 2001-10), p. 425-431
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 29, No. 5 ( 2001-10), p. 425-431
    Abstract: Simultaneous treatment with peripheral blood stem-cell (PBSC) transplantation and intensive chemotherapy was evaluated in a case of non-Hodgkin's lymphoma (NHL) with poor prognosis. A 59-year-old male diagnosed with a high-grade, anaplastic large-cell (Ki-1) NHL, involving fractures in the left hip, underwent computed tomography and gallium scintigram surveillance. The patient received chemotherapy with epirubicin hydrochloride, cyclophosphamide, vincristine and prednisolone, and the fractured hip bone was repaired following the first course of chemotherapy. After the second and third courses of chemotherapy, PBSCs were harvested and cryopreserved. The patient then received a further course of chemotherapy and PBSC transplantation was conducted using infused cells consisting of 9.63 × 10 6 /kg CD34 cells and 2.24 × 10 5 /kg granulocyte macrophage colony-forming units. Recovery of platelet and white blood cell counts occurred 10 and 8 days, respectively, after PBSC infusion and the patient remains well.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/147323000102900507
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2001
    detail.hit.zdb_id: 2082422-1
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    Online Resource
  • 3
    Online Resource
    Online Resource
    Prolactin Binds to Human Endometrial Fibroblasts and Inhibits Mitogenicity of an Endometrial Carcinoma Extract
    SAGE Publications ; 1993
    In:  Experimental Biology and Medicine Vol. 203, No. 1 ( 1993-05-01), p. 117-122
    Details
    In: Experimental Biology and Medicine, SAGE Publications, Vol. 203, No. 1 ( 1993-05-01), p. 117-122
    Type of Medium: Online Resource
    ISSN: 1535-3702 , 1535-3699
    URL: Article
    DOI: 10.3181/00379727-203-43581a
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1993
    detail.hit.zdb_id: 2020856-X
    SSG: 12
    Location Call Number Limitation Availability
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    Online Resource
  • 4
    Online Resource
    Online Resource
    Performance and System Validation of a New Cellular-Enabled Blood Glucose Monitoring System Using a New Standard Reference Measurement Procedure of Isotope Dilution UPLC-MRM Mass Spectrometry
    SAGE Publications ; 2015
    In:  Journal of Diabetes Science and Technology Vol. 9, No. 5 ( 2015-09-01), p. 1061-1070
    Details
    In: Journal of Diabetes Science and Technology, SAGE Publications, Vol. 9, No. 5 ( 2015-09-01), p. 1061-1070
    Abstract: We evaluated the accuracy, precision, and linearity of the In Touch® blood glucose monitoring system (BGMS), a new color touch screen and cellular-enabled blood glucose meter, using a new rapid, highly precise and accurate 13 C 6 isotope-dilution liquid chromatography-mass spectrometry method (IDLC-MS). Methods: Blood glucose measurements from the In Touch® BGMS were referenced to a validated UPLC-MRM standard reference measurement procedure previously shown to be highly accurate and precise. Readings from the In Touch® BGMS were taken over the blood glucose range of 24-640 mg/dL using 12 concentrations of blood glucose. Ten In Touch® BGMS and 3 lots of test strips were used with 10 replicates at each concentration. A lay user study was also performed to assess the ease of use. Results: At blood glucose concentrations 〈 75 mg/dL 100% of the measurements are within ±8 mg/dL from the true reference standard; at blood glucose levels 〉 75 mg/dL 100% of the measurements are within ±15% of the true reference standard. 100% of the results are within category A of the consensus grid. Within-run precision show CV 〈 3.72% between 24-50 mg/dL and CV 〈 2.22% between 500 and 600 mg/dL. The results show that the In Touch® meter exceeds the minimum criteria of both the ISO 15197:2003 and ISO 15197:2013 standards. The results from a user panel show that 100% of the respondents reported that the color touch screen, with its graphic user interface (GUI), is well labeled and easy to navigate. Conclusions: To our knowledge this is the first touch screen glucose meter and the first study where accuracy of a new BGMS has been measured against a true primary reference standard, namely IDLC-MS.
    Type of Medium: Online Resource
    ISSN: 1932-2968 , 1932-2968
    URL: Article
    DOI: 10.1177/1932296815586016
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2467312-2
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    Online Resource
  • 5
    Online Resource
    Online Resource
    Pathophysiology of β2-glycoprotein I in antiphospholipid syndrome
    SAGE Publications ; 2010
    In:  Lupus Vol. 19, No. 4 ( 2010-04), p. 379-384
    Details
    In: Lupus, SAGE Publications, Vol. 19, No. 4 ( 2010-04), p. 379-384
    Abstract: Since β 2 -glycoprotein I (β 2 GPI) was described as the major antigenic target for antiphospholipid antibodies, many studies have focused their attention to the physiological role of β 2 GPI and anti-β 2 GPI antibodies on autoimmune-mediated thrombosis. Studies reporting the physiological role of β 2 GPI have been numerous, but the exact mechanism of action(s) has yet to be completely determined. β 2 GPI’s epitopes for anti-β 2 GPI autoantibodies have been characterized, however, not all of the heterogeneous anti-β 2 GPI antibodies are pathogenic. The pathophysiologic role of β 2 GPI has been reported in the fields of coagulation, fibrinolysis, angiogenesis, and atherosclerosis. Our understanding of the impact of β 2 GPI, its metabolites and autoantibodies to β 2 GPI on these physiological functions may contribute to the development of better therapeutic strategies to treat and prevent autoimmune-mediated atherothrombotic vascular disease. Lupus (2010) 19, 379—384.
    Type of Medium: Online Resource
    ISSN: 0961-2033 , 1477-0962
    URL: Article
    DOI: 10.1177/0961203310361352
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2010
    detail.hit.zdb_id: 2008035-9
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  • 6
    Online Resource
    Online Resource
    Treatment of Acute Myeloblastic Leukaemia in a Patient with Bombay Blood Type: A Case Report
    SAGE Publications ; 2001
    In:  Journal of International Medical Research Vol. 29, No. 2 ( 2001-04), p. 140-146
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 29, No. 2 ( 2001-04), p. 140-146
    Abstract: A 62-year-old female was admitted to our hospital with suspected acute leukaemia and after investigation we diagnosed acute myeloblastic leukaemia (AML-M1). The patient's blood type was found to be the very rare Bombay type and surveillance of her relatives showed the same blood type in her male cousin on her mother's side. Alongside chemotherapy the patient received 4000 ml of frozen Bombay-type red cells, 1400 ml of concentrated red cells in manitol adenine phosphate solutions and 360 units of type O concentrated platelets without marked effects. The anti-H antibody was initially at 128 dilution but for unknown reasons increased to 2048 dilution after remission of AML-M1. About 3 months after hospitalization the patient died of Cryptococcus neoformans pneumonia despite strict precautions against infection. Although AML-M1 is a common adult leukaemia and is chemosensitive to anti-leukaemic drugs, neither AML-M1 in a patient with Bombay-type red cells nor its treatment with chemotherapy and transfusion with type Oh frozen red cells have previously been reported.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/147323000102900211
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2001
    detail.hit.zdb_id: 2082422-1
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    Online Resource
  • 7
    Online Resource
    Online Resource
    Development and Validation of a Rapid 13 C 6 -Glucose Isotope Dilution UPLC-MRM Mass Spectrometry Method for Use in Determining System Accuracy and Performance of Blood Glucose Monitoring Devices
    SAGE Publications ; 2015
    In:  Journal of Diabetes Science and Technology Vol. 9, No. 5 ( 2015-09-01), p. 1051-1060
    Details
    In: Journal of Diabetes Science and Technology, SAGE Publications, Vol. 9, No. 5 ( 2015-09-01), p. 1051-1060
    Abstract: There is currently considerable discussion about the accuracy of blood glucose concentrations determined by personal blood glucose monitoring systems (BGMS). To date, the FDA has allowed new BGMS to demonstrate accuracy in reference to other glucose measurement systems that use the same or similar enzymatic-based methods to determine glucose concentration. These types of reference measurement procedures are only comparative in nature and are subject to the same potential sources of error in measurement and system perturbations as the device under evaluation. It would be ideal to have a completely orthogonal primary method that could serve as a true standard reference measurement procedure for establishing the accuracy of new BGMS. Methods: An isotope-dilution liquid chromatography/mass spectrometry (ID-UPLC-MRM) assay was developed using 13 C 6 -glucose as a stable isotope analogue to specifically measure glucose concentration in human plasma, and validated for use against NIST standard reference materials, and against fresh isolates of whole blood and plasma into which exogenous glucose had been spiked. Assay performance was quantified to NIST-traceable dry weight measures for both glucose and 13 C 6 -glucose. Results: The newly developed assay method was shown to be rapid, highly specific, sensitive, accurate, and precise for measuring plasma glucose levels. The assay displayed sufficient dynamic range and linearity to measure across the range of both normal and diabetic blood glucose levels. Assay performance was measured to within the same uncertainty levels ( 〈 1%) as the NIST definitive method for glucose measurement in human serum. Conclusions: The newly developed ID UPLC-MRM assay can serve as a validated reference measurement procedure to which new BGMS can be assessed for glucose measurement performance.
    Type of Medium: Online Resource
    ISSN: 1932-2968 , 1932-2968
    URL: Article
    DOI: 10.1177/1932296815586015
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2467312-2
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