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  • 1
    Online Resource
    Online Resource
    Primary red ear syndrome associated with cochleo-vestibular symptomatology: A paediatric case report
    SAGE Publications ; 2013
    In:  Cephalalgia Vol. 33, No. 15 ( 2013-11), p. 1277-1280
    Details
    In: Cephalalgia, SAGE Publications, Vol. 33, No. 15 ( 2013-11), p. 1277-1280
    Abstract: Red ear syndrome (RES), first described by Lance in 1996 in an adult series, may be primary or associated with headache syndromes, upper cervical disorders or vascular anomalies. Clinically the disease is characterised by recurrent episodes of reddening and burning pain in the auricle, usually elicited by different triggers. The prevalence of RES in the paediatric age group remains poorly understood. Several therapeutic approaches have been tried with heterogeneous clinical response. Case results We report a paediatric patient suffering from primary RES associated with debilitating cochleo-vestibular symptomatology causing severe discomfort. Three years after the disease onset, the patient also developed headache, with clinical features of migraine. Discussion The temporal and spatial association could suggest shared pathogenetic features between neurological (cochleo-vestibular) and vascular (red and burning ear) symptomatology, likely related to trigeminal autonomic reflex activation, although further studies are required for full comprehension of RES pathogenesis.
    Type of Medium: Online Resource
    ISSN: 0333-1024 , 1468-2982
    URL: Article
    DOI: 10.1177/0333102413493527
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2019999-5
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  • 2
    Online Resource
    Online Resource
    The Bodily Illusion in Adverse Conditions: Virtual Arm Ownership During Visuomotor Mismatch
    SAGE Publications ; 2018
    In:  Perception Vol. 47, No. 5 ( 2018-05), p. 477-491
    Details
    In: Perception, SAGE Publications, Vol. 47, No. 5 ( 2018-05), p. 477-491
    Abstract: Classically, body ownership illusions are triggered by cross-modal synchronous stimulations, and hampered by multisensory inconsistencies. Nonetheless, the boundaries of such illusions have been proven to be highly plastic. In this immersive virtual reality study, we explored whether it is possible to induce a sense of body ownership over a virtual body part during visuomotor inconsistencies, with or without the aid of concomitant visuo-tactile stimulations. From a first-person perspective, participants watched a virtual tube moving or an avatar’s arm moving, with or without concomitant synchronous visuo-tactile stimulations on their hand. Three different virtual arm/tube speeds were also investigated, while all participants kept their real arms still. The subjective reports show that synchronous visuo-tactile stimulations effectively counteract the effect of visuomotor inconsistencies, but at slow arm movements, a feeling of body ownership might be successfully induced even without concomitant multisensory correspondences. Possible therapeutical implications of these findings are discussed.
    Type of Medium: Online Resource
    ISSN: 0301-0066 , 1468-4233
    URL: Article
    DOI: 10.1177/0301006618758211
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2013004-1
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  • 3
    Online Resource
    Online Resource
    Warm-up exercises reduce music conservatoire students’ pain intensity when controlling for mood, sleep and physical activity: A pilot study
    SAGE Publications ; 2023
    In:  British Journal of Pain
    Details
    In: British Journal of Pain, SAGE Publications
    Abstract: Playing-related musculoskeletal pain is highly prevalent among classical music students, affecting them physically and psychologically. Unlike athletes or dancers, musicians’ pain often goes untreated due to stigma and lack of specialised healthcare. While warm-up exercises are common practice in sports and dance, there is a lack of empirical research regarding physical warm-ups for musicians’ pain. This study aimed to investigate the effects of a 2-week daily warm-up exercise intervention on conservatoire students’ pain intensity, interference and psychological distress, at day 0 and after 2 weeks. Methods Two groups were considered: an exercise ( n = 9) and a waitlist control ( n = 7) group. Data were collected using online Qualtrics surveys at three different stages. Results 2 × 2 mixed ANOVAs indicated no significant effects on any of the outcome variables. However, when controlling for sleep, anxiety, depression and physical activity, the analyses revealed a significantly greater decrease in pain intensity in the exercise group compared to the control. In addition, bivariate correlations indicated that pain interference, anxiety and depression delta scores were significantly correlated for the exercise but not the control group. Anxiety and pain intensity delta scores were significantly correlated in both groups. Conclusions These findings suggest that daily warm-up exercises have the potential to reduce musicians’ pain intensity but only if certain variables are factored in. This pilot study highlights the multifactorial nature of musicians’ pain and unveils the role that mood, sleep and physical activity level may have when assessing the efficacy of interventions based on warm-up exercises.
    Type of Medium: Online Resource
    ISSN: 2049-4637 , 2049-4645
    URL: Article
    DOI: 10.1177/20494637231188306
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2670872-3
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  • 4
    Online Resource
    Online Resource
    Combination of Epirubicin and Lonidamine for Treatment of Advanced Breast Cancer
    SAGE Publications ; 1995
    In:  Tumori Journal Vol. 81, No. 2 ( 1995-03), p. 107-111
    Details
    In: Tumori Journal, SAGE Publications, Vol. 81, No. 2 ( 1995-03), p. 107-111
    Abstract: In vitro and in vivo studies have shown that lonidamine potentiates the cytotoxic effect of anthracyclines in simultaneous and sequential combination. On the basis of such evidence, we evaluated the activity and toxicity of a combination of epirubicin plus lonidamine in advanced breast cancer. Methods Between January 1991 and November 1993, 33 patients with advanced breast cancer, age 〈 75 years and PS 〈 2, were treated with epirubicin (75 mg/m 2 i.v. on day 1, every 3 weeks), plus lonidamine (450 mg/day orally from day 1 continuously until disease progression). Results Thirty patients were evaluable for response: 4 achieved complete response (13%) and 8 partial response (27%) (total response rate = 40%), 6 (20%) had stabilization of disease, and 12 (40%) progression of disease. The median duration of response was 10 months (range, 4-24+ months). This scheme was tolerated, with a mild additional toxicity related to lonidamine: only WHO grade III myalgia in 1 patient (3%) and epigastralgia in 3 patients (9%). Conclusions Although some patients seem to have benefited from the combination at the dose levels of the drug used in the study, the therapeutic advantages of addition of lonidamine remain unclear.
    Type of Medium: Online Resource
    ISSN: 0300-8916 , 2038-2529
    URL: Article
    DOI: 10.1177/030089169508100207
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1995
    detail.hit.zdb_id: 280962-X
    detail.hit.zdb_id: 2267832-3
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  • 5
    Online Resource
    Online Resource
    Maintaining sexuality in menopause
    SAGE Publications ; 2014
    In:  Post Reproductive Health Vol. 20, No. 1 ( 2014-03), p. 22-29
    Details
    In: Post Reproductive Health, SAGE Publications, Vol. 20, No. 1 ( 2014-03), p. 22-29
    Abstract: Sexual health in the menopause is a medical challenge because the progressive decline of sexual hormones interacts with the aging process and many psychosocial stressors modulate vulnerability for sexual symptoms (low sexual desire, poor arousal and lubrication, dyspareunia, orgasmic dysfunction and lack of satisfaction). In clinical practice, a coordinated approach is needed to optimally manage the risk for developing female sexual dysfunction (FSD), especially when chronic conditions are present. Biomedical and psychosocial interventions include general education, recognition of signs and symptoms, promotion of health, attention to the partner and individualization of treatment. Counselling to overcome personal and relational difficulties should be always combined with hormonal and non-hormonal strategies to maximize biological signals driving the sexual response. By enhancing women’s abilities to cope with sexual changes at midlife, health care providers may significantly optimize healthy aging and partnership.
    Type of Medium: Online Resource
    ISSN: 2053-3691 , 2053-3705
    URL: Article
    DOI: 10.1177/1754045313515122
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2762966-1
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  • 6
    Online Resource
    Online Resource
    Gemcitabine and Carboplatin Treatment in Advanced NSCLC: A Retrospective Evaluation Including Elderly Patients
    SAGE Publications ; 2009
    In:  Tumori Journal Vol. 95, No. 1 ( 2009-01), p. 36-42
    Details
    In: Tumori Journal, SAGE Publications, Vol. 95, No. 1 ( 2009-01), p. 36-42
    Abstract: Carboplatin-containing regimens are sometimes preferred for patients with advanced non-small cell lung cancer. Methods Eighty-three patients with stage III-IV non-small cell lung cancer received 3 to 4 cycles of carboplatin AUC 5 on day 2 and gemcitabine 1250 mg/m 2 on days 1 and 8 every 21 days. Results The overall response rate was 43.4%. Results obtained from elderly and non-elderly groups were compared using the logrank method. Median overall survival and progression-free survival were 11 and 7 months, respectively (12 and 7 months, non-elderly group; 6.5 and 5 months, elderly group, P = 0.28 and 0.25 respectively). Grade 3–4 toxicity included neutropenia, thrombocytopenia, anemia, nausea/vomiting, and diarrhea. Incidences of grade 3–4 toxicity were similar for elderly and non-elderly patients. Conclusions Data confirm that carboplatin-gemcitabine is an active and well-tolerated regimen in advanced non-small cell lung cancer and could be investigated in elderly patients.
    Type of Medium: Online Resource
    ISSN: 0300-8916 , 2038-2529
    URL: Article
    DOI: 10.1177/030089160909500107
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 280962-X
    detail.hit.zdb_id: 2267832-3
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  • 7
    Online Resource
    Online Resource
    Implementation of evidence-based medicine in dietetic practice: Current status and hurdles in Italy
    SAGE Publications ; 2024
    In:  Nutrition and Health
    Details
    In: Nutrition and Health, SAGE Publications
    Abstract: Background: Health professionals, including dietitians, should adapt their clinical daily practice to evidence-based practice (EBP), but this does not happen often in daily practice. The aim of this study was to investigate the current status and barriers to evidence-based practice among dietitians. Methods: This was a mixed-method, cross-sectional, national study (questionnaire and focus group) performed on working and registered dietitians, both self-employed and employed by public hospitals. The main outcomes were EBP knowledge, frequency of use, and proficiency scores. Barriers to EBP implementation were also collected, as well as qualitative information from the focus group. Results: Forty-three dietitians were enrolled from August to November 2021 in Italy. Overall, EBP knowledge was moderate/good. Younger dietitians ( 〈 50 years old) obtained better results than their older colleagues. A similar trend was observed in terms of seniority. There was a discrepancy between EBP knowledge and perception of EBP implementation: the worst scores were obtained by participants who claimed an already complete integration of EBP. The average frequency of EBP use was moderate, with higher scores in dietitians ≥ 50 years old and with seniority ≥ 20 years. EBP proficiency instead was poor. The focus group revealed a lack of time and resistance to change as the main barriers. Conclusion: The importance of EBP is well-acknowledged, but it is not correctly implemented yet, because of identified barriers that need to be fixed. These barriers include a lack of dedicated time, inadequate EBP training, and resistance to change, especially in hierarchical environments.
    Type of Medium: Online Resource
    ISSN: 0260-1060 , 2047-945X
    URL: Article
    DOI: 10.1177/02601060241254563
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2024
    detail.hit.zdb_id: 2647106-1
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