GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • SAGE Publications  (15)
  • 1
    Online Resource
    Online Resource
    Optimal Design of Filament Winding Using Neural Network Experimental Design Scheme
    SAGE Publications ; 1999
    In:  Journal of Composite Materials Vol. 33, No. 24 ( 1999-12), p. 2281-2300
    Details
    In: Journal of Composite Materials, SAGE Publications, Vol. 33, No. 24 ( 1999-12), p. 2281-2300
    Abstract: The goal of this paper is to design the filament winding in composites materials based on our previous developed technique. The most significant parameters in design and construction of composites prepared by filament winding are resin temperature, fiber tension and winding angle. The three variables depict nonlinear relationship; thus a nonlinear modeling technique is required. The proposed methodology enjoys many of the advantages claimed for the artificial neural network (ANN), random search optimization, fuzzy classification and information theory for the sequential design filament winding. The neural network is used to construct a model based on the currently available experimental data. Random search generates a number of candidates of the next batch of experiments. Fuzzy classification and information analysis are defined to balance the need of better classification and the relevance of each class in optimization. The test results of the proposed method show that the abilities of the proposed methodology handle multivariable experimental design and also help experimenters discuss complex trade-offs between practical limitation and statistical preferences in the experiment.
    Type of Medium: Online Resource
    ISSN: 0021-9983 , 1530-793X
    URL: Article
    DOI: 10.1177/002199839903302403
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1999
    detail.hit.zdb_id: 160490-9
    detail.hit.zdb_id: 2081924-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Expert consensus for PVCR in severe, rigid and angular spinal deformity treatment: The Kunming consensus
    SAGE Publications ; 2017
    In:  Journal of Orthopaedic Surgery Vol. 25, No. 2 ( 2017-05), p. 230949901771393-
    Details
    In: Journal of Orthopaedic Surgery, SAGE Publications, Vol. 25, No. 2 ( 2017-05), p. 230949901771393-
    Type of Medium: Online Resource
    ISSN: 2309-4990 , 2309-4990
    URL: Article
    DOI: 10.1177/2309499017713939
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2128854-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Prevalence and the associated risk factors of HIV, STIs and HBV among men who have sex with men in Kunming, China
    SAGE Publications ; 2017
    In:  International Journal of STD & AIDS Vol. 28, No. 11 ( 2017-10), p. 1115-1123
    Details
    In: International Journal of STD & AIDS, SAGE Publications, Vol. 28, No. 11 ( 2017-10), p. 1115-1123
    Abstract: To investigate the prevalence and the associated risk factors of human immunodeficiency virus (HIV), hepatitis B virus (HBV) and sexually transmitted infections (STIs) among men who have sex with men (MSM) in Kunming, 300 MSM were recruited through community-based organizations between September 2014 and January 2015. The prevalence of HIV, HBsAg, syphilis, Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) were 17.0%, 7.7%, 11.3%, 18.2% and 13.2%, respectively. In the three different anatomic sites (urethra, rectum and pharynx), the prevalence of rectal CT was the highest (15.5%), whereas NG was most commonly found in the pharynx (8.1%). Low education level, homosexuality, inconsistent condom use and drug use in the previous six months were significantly associated with HIV infection, whereas the former three factors were also associated with HBV infection.Older people (aged ≥ 40 years) and those who lacked knowledge of STIs, and younger people (aged 〈 30 years) as well as inconsistent condom users were more at risk of syphilis and CT infections, respectively. NG infection was only associated with reported dating venues. Our study revealed a heavy disease burden and multiple risk factors of HIV/STIs among MSM in Kunming. It is necessary to promote regular screening and proactive treatment of HIV/STIs among MSM.
    Type of Medium: Online Resource
    ISSN: 0956-4624 , 1758-1052
    URL: Article
    DOI: 10.1177/0956462416688818
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2009782-7
    detail.hit.zdb_id: 1018089-8
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Add-on immunosuppressive therapy may benefit selected patients with primary biliary cholangitis and autoimmune phenomena
    SAGE Publications ; 2024
    In:  Therapeutic Advances in Gastroenterology Vol. 17 ( 2024-01)
    Details
    In: Therapeutic Advances in Gastroenterology, SAGE Publications, Vol. 17 ( 2024-01)
    Abstract: Plain language summary A look at add-on immunosuppressive therapy in primary biliary cholangitis patients Adding immunosuppressive therapy may enhance the normalization of ALT, AST and IgG levels in all PBC patients with mild elevation and improve long-term outcomes in those with more severe elevation of ALT, AST and IgG. These findings contribute to our understanding of treatment options for PBC patients with autoimmune phenomena.
    Type of Medium: Online Resource
    ISSN: 1756-2848 , 1756-2848
    URL: Article
    DOI: 10.1177/17562848231224840
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2024
    detail.hit.zdb_id: 2440710-0
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    RETRACTED: Toll-like receptor 2/4 inhibitors can reduce preterm birth in mice
    SAGE Publications ; 2020
    In:  Journal of International Medical Research Vol. 48, No. 10 ( 2020-10), p. 030006052093379-
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 48, No. 10 ( 2020-10), p. 030006052093379-
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/0300060520933795
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 184023-X
    detail.hit.zdb_id: 2082422-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Molecular fingerprint of precancerous lesions in breast atypical hyperplasia
    SAGE Publications ; 2020
    In:  Journal of International Medical Research Vol. 48, No. 6 ( 2020-06), p. 030006052093161-
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 48, No. 6 ( 2020-06), p. 030006052093161-
    Abstract: To identify atypical hyperplasia (AH) of the breast by shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS), and to explore the molecular fingerprinting characteristics of breast AH. Methods Breast hyperplasia was studied in 11 hospitals across China from January 2015 to December 2016. All patients completed questionnaires on women’s health. The differences between patients with and without breast AH were compared. AH breast lesions were detected by Raman spectroscopy followed by the SHINERS technique. Results There were no significant differences in clinical features and risk-related factors between patients with breast AH (n = 37) and the control group (n = 2576). Fifteen cases of breast AH lesions were detected by Raman spectroscopy. The main different Raman peaks in patients with AH appeared at 880, 1001, 1086, 1156, 1260, and 1610 cm −1 , attributed to the different vibrational modes of nucleic acids, β-carotene, and proteins. Shell-isolated nanoparticles had different enhancement effects on the nucleic acid, protein, and lipid components in AH. Conclusion Raman spectroscopy can detect characteristic molecular changes in breast AH lesions, and may thus be useful for the non-invasive early diagnosis and for investigating the mechanism of tumorigenesis in patients with breast AH.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/0300060520931616
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 184023-X
    detail.hit.zdb_id: 2082422-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Molecular Subtype Approximated by Quantitative Estrogen Receptor, Progesterone Receptor and Her2 Can Predict the Prognosis of Breast Cancer
    SAGE Publications ; 2010
    In:  Tumori Journal Vol. 96, No. 1 ( 2010-01), p. 103-110
    Details
    In: Tumori Journal, SAGE Publications, Vol. 96, No. 1 ( 2010-01), p. 103-110
    Abstract: To investigate the clinicopathological characteristics and prognosis of breast cancer subtypes classified by quantitative estrogen receptor (ER), progesterone receptor (PR), and Her2. Methods and study design 923 patients with primary breast cancer having a median age of 53 years who were treated at the Cancer Hospital of Fudan University in Shanghai between January 2002 and June 2004 were retrospectively analyzed. Four molecular subtypes were constructed from the immunohistochemical results of quantitative hormone receptor (HR) and Her2 status. HR+ was defined as ER+ and PR+, HR± as ER/PR+ at lower levels or lacking either ER or PR, and HR- as both ER- and PR-. The four subtypes were HR+/Her2-, HR±/Her2-, HR-/Her2- (triple-negative), and Her2+. Clinical and pathological parameters, disease-free survival (DFS), and overall survival (OS) measurements were compared between patients with different molecular subtypes. Results The proportions of HR+/Her2-, HR±/Her2-, triple-negative, and Her2+ breast cancer were 36.6% (338/923), 22.9% (211/923), 20.6% (190/923), and 19.9% (194/923). The median follow-up was 49.0 months (4–77 months). In 145 cases disease recurrence or death occurred. In multivariate analysis with the HR+/Her2- subtype taken as the reference category, triple-negative and Her2+ subtypes were associated with increased recurrence and death with a hazard ratio (HR) of 2.05 (95% CI 1.31–3.20; P = 0.002) and 1.89 (95% CI 1.20–2.97, P = 0.006) for DFS and 2.84 (95% CI 1.45–5.55; P = 0.002) and 2.95 (95% CI 1.51–5.77, P = 0.002) for OS, respectively; the HR±/Her2- subtype was marginally associated with poor prognosis with HR 1.51 (95% CI 0.94–2.43; P = 0.088) and 1.90 (95% CI 0.92–3.94; P = 0.084) for DFS and OS, respectively. Conclusions Breast cancer subtypes based on quantitative ER, PR, and Her2 may be predictive of prognosis. Patients whose tumors were not HR+/Her2- had a worse outcome in our study.
    Type of Medium: Online Resource
    ISSN: 0300-8916 , 2038-2529
    URL: Article
    DOI: 10.1177/030089161009600117
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2010
    detail.hit.zdb_id: 2086597-1
    detail.hit.zdb_id: 2267832-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    Manufacture and characterization of carbon fiber composite stiffened skin by resin film infusion/prepreg co-curing process
    SAGE Publications ; 2014
    In:  Journal of Reinforced Plastics and Composites Vol. 33, No. 17 ( 2014-09), p. 1559-1573
    Details
    In: Journal of Reinforced Plastics and Composites, SAGE Publications, Vol. 33, No. 17 ( 2014-09), p. 1559-1573
    Abstract: I-shaped stiffened skin was manufactured by a new co-cured resin film infusion process (co-RFI) with fiber preform stiffener and prepreg skin. One kind of epoxy resin film and four kinds of carbon fiber prepreg were used. Resin flow behavior, processing quality, and mechanical performance were investigated for co-RFI stiffened skin. Sole prepreg/autoclave process and resin film infusion process were also adopted for comparison. Resin flow front and resin pressure were detected by self-developed monitoring systems. Optical micrographs and thickness measurement were employed to evaluate processing quality. Moreover, pull-off test was used to analyze the influences of core filler and prepreg systems in skin on the mechanical performance of stiffened skin. The results show that with reasonable processing conditions, good processing quality, and mechanical property at co-curing interface region can be achieved for co-RFI stiffened skin. Co-RFI process is suitable to fabricate composite structure with high flexibility in materials and structures.
    Type of Medium: Online Resource
    ISSN: 0731-6844 , 1530-7964
    URL: Article
    DOI: 10.1177/0731684414543213
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2051886-9
    detail.hit.zdb_id: 783961-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    First-in-Human Clinical Trial of the WeFlow-JAAA Endograft System in Patients With Juxtarenal Abdominal Aortic Aneurysms
    SAGE Publications ; 2023
    In:  Journal of Endovascular Therapy
    Details
    In: Journal of Endovascular Therapy, SAGE Publications
    Abstract: To preliminarily evaluate the safety and efficacy of the WeFlow-JAAA endograft, a novel off-the-shelf device designed for the repair of juxtarenal abdominal aortic aneurysms (JRAAAs) and pararenal abdominal aortic aneurysms (PRAAAs). Methods: This prospective single-arm first-in-human clinical trial included patients with JRAAAs (infrarenal necks ≤10 mm) or PRAAAs with at least a 5 mm sealing zone below the superior mesenteric artery (SMA) who underwent endovascular repair using the WeFlow-JAAA endograft system. With this system, the celiac artery was addressed with a wide scallop, the renal arteries (RAs) were addressed with 2 standard inner branches, and the SMA was addressed with a “mini-inner-cuff” reinforced fenestration. The primary efficacy endpoint was the clinical success at 12 months. The primary safety endpoint was the freedom from major adverse events (MAEs) in the first 30 days after surgery. Results: Fifteen patients (all men; mean age 68.5±6.0 years) were enrolled between October 2019 and August 2021. The median infrarenal neck length was 0 mm (IQR, 0–4 mm). Technical success was achieved in all patients. No MAEs occurred in the first 30 days. The mean fluoroscopy time was 73.1±27.8 minutes, and the mean volume of contrast media was 130.7±29.4 mL. Clinical success was maintained in all patients at 12 months. No aortic-related deaths, aneurysm rupture, type I or type III endoleak, or open surgery conversion occurred during the follow-up period. The secondary intervention was required only in 1 patient who developed an occluded right RA stent 14 months after the procedure. Conclusion: The WeFlow-JAAA endograft device appears to be safe and efficacious in selected patients with JRAAAs or PRAAAs with more than 5 mm sealing zone below SMA. Large-scale, multicenter, and prospective studies with long-term follow-ups are ongoing to validate our findings in China. Trial Registration: Clinicaltrials.gov identifier: NCT04745546 (URL: Guo’s Visceral Arteries Reconstruction: The First in Man Study of WeFlow-JAAA Stent Graft System—Full-Text View—ClinicalTrials.gov) Clinical Impact The first-in-human clinical trial of the WeFlow-JAAA endograft system demonstrates promising safety and efficacy in treating juxtarenal abdominal aortic aneurysms (JRAAAs) and partial pararenal abdominal aortic aneurysms (PRAAAs). This innovative off-the-shelf device offers a potential alternative to traditional endovascular aortic repair. The successful outcomes, including technical success in all patients, freedom from major adverse events, and maintenance of clinical success at 12 months, suggest a potential shift in clinical practice towards using the WeFlow-JAAA endograft system for selected patients. This study paves the way for larger-scale, multicenter, prospective studies to further validate its long-term safety and efficacy, offering clinicians a new option for managing complex abdominal aortic aneurysms.
    Type of Medium: Online Resource
    ISSN: 1526-6028 , 1545-1550
    URL: Article
    DOI: 10.1177/15266028231210480
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2006618-1
    detail.hit.zdb_id: 2049858-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Comparison of staining quality between rapid and routine hematoxylin and eosin staining of frozen breast tissue sections: an observational study
    SAGE Publications ; 2024
    In:  Journal of International Medical Research Vol. 52, No. 6 ( 2024-06)
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 52, No. 6 ( 2024-06)
    Abstract: To compare the staining quality between rapid hematoxylin and eosin (H & E) staining and routine H & E staining of frozen breast tissue sections. Methods In this cross-sectional observational study, 120 frozen breast tissue sections were randomly assigned to rapid or routine H & E staining ( n = 60 per group). Rapid H & E staining used a 7:1 mixture of modified Gill’s hematoxylin and alcohol-soluble 1% eosin Y. The staining quality of each section was evaluated and scored. A score of 〉 7 was considered excellent, a score of 6 to 7 good, and a score of ≤5 poor. Results The staining time for rapid staining was approximately 3 minutes, whereas that of routine staining was approximately 12 minutes. There were no significant differences in the staining quality scores or proportions of sections in each grade between the two staining methods. The proportions of sections that were classified as excellent or good were 96.7% and 98.3% for rapid and routine staining, respectively. Conclusions In frozen breast tissue sections, rapid H & E staining may provide staining quality that is comparable to that of routine staining, while markedly reducing the staining time.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/03000605241259682
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2024
    detail.hit.zdb_id: 184023-X
    detail.hit.zdb_id: 2082422-1
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...