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  • SAGE Publications  (22)
  • 1
    In: Journal of Cerebral Blood Flow & Metabolism, SAGE Publications, Vol. 42, No. 12 ( 2022-12), p. 2287-2302
    Abstract: The glymphatic-lymphatic fluid transport system (GLFTS) consists of glymphatic pathway and cerebrospinal fluid (CSF) lymphatic outflow routes, allowing biological liquids from the brain parenchyma to access the CSF along with perivascular space and to be cleaned out of the skull through lymphatic vessels. It is known that increased local pressure due to physical compression of tissue improves lymphatic transport in peripheral organs, but little is known about the exact relationship between increased intracranial pressure (IICP) and GLFTS. In this study, we verify our hypothesis that IICP significantly impacts GLFTS, and this effect depends on severity of the IICP. Using a previously developed inflating balloon model to induce IICP and inject fluorescent tracers into the cisterna magna, we found significant impairment of the glymphatic circulation after IICP. We further found that cerebrovascular occlusion occurred, and cerebrovascular pulsation decreased after IICP. IICP also interrupted the drainage of deep cervical lymph nodes and dorsal meningeal lymphatic function, enhancing spinal lymphatic outflow to the sacral lymph nodes. Notably, these effects were associated with the severity of IICP. Thus, our findings proved that the intensity of IICP significantly impacts GLFTS. This may have translational applications for preventing and treating related neurological disorders.
    Type of Medium: Online Resource
    ISSN: 0271-678X , 1559-7016
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2039456-1
    detail.hit.zdb_id: 604628-9
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 2024
    In:  Transportation Research Record: Journal of the Transportation Research Board Vol. 2678, No. 7 ( 2024-07), p. 188-207
    In: Transportation Research Record: Journal of the Transportation Research Board, SAGE Publications, Vol. 2678, No. 7 ( 2024-07), p. 188-207
    Abstract: The airport road traffic sign system is essential for drivers to find their destinations. However, no comprehensive design standards have been established for airport roadway traffic signs in China. An airport roadway traffic sign system was designed based on the Chinese Road Traffic Signs and Markings standard (GB5768-2009), called scheme 1. A second sign system was established using international standards and following drivers’ recognition, sign information hierarchy, called scheme 2. The Airport Roadway Traffic Sign System Evaluation Method (ARTSSEM) was established to evaluate the effectiveness of the airport roadway traffic sign system. This method includes a goal layer, a method layer, an indicator layer, and a comprehensive evaluation layer. We obtained drivers’ driving behavior data from the driving simulation. The subjects drove at a lower and more stable average speed in scheme 2 (63.71 ± 3.91) than in scheme 1 (65.89 ± 4.81). An ergonomic model that considers the sign system’s information demand, information comprehension, and information volume (DCI) was established and evaluated using subjective experiments. Scheme 2 provided a higher DCI score (0.46) than scheme 1 (0.17). The performance of the sign systems was comprehensively evaluated using the fuzzy evaluation method to evaluate the driving behavior, wayfinding performance, and ergonomics of the sign system. Scheme 2 (76.13) had a higher score than scheme 1 (74.13). The results revealed that scheme 2 performed better than scheme 1. The effectiveness of ARTSSEM was verified by the case study of the Daxing Airport signage system. This study provides a general approach to designing and evaluating other sign systems.
    Type of Medium: Online Resource
    ISSN: 0361-1981 , 2169-4052
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2024
    detail.hit.zdb_id: 190260-X
    detail.hit.zdb_id: 2403378-9
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Journal of Vibration and Control Vol. 25, No. 6 ( 2019-03), p. 1263-1278
    In: Journal of Vibration and Control, SAGE Publications, Vol. 25, No. 6 ( 2019-03), p. 1263-1278
    Abstract: Wind turbines revolve in difficult operating conditions due to stochastic loads and produce massive vibration signals, which cause obstacles in detecting potential fault information. To overcome this, an adaptive fault detection approach is presented in this paper on the basis of parameterless empirical wavelet transform (PEWT) and the margin factor. PEWT can decompose the vibration signal into a series of empirical modes (EMs) through splitting its Fourier spectrum, using the scale space method and adaptively constructing an orthogonal wavelet filter bank. The margin factor is utilized as a key metric for automatically selecting the EM which is sensitive to the potential faults. The method presented in this paper will improve the efficiency and accuracy of fault information for the condition monitoring of wind turbines.
    Type of Medium: Online Resource
    ISSN: 1077-5463 , 1741-2986
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 1306262-1
    detail.hit.zdb_id: 2070247-4
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2000
    In:  Journal of Cerebral Blood Flow & Metabolism Vol. 20, No. 9 ( 2000-09), p. 1294-1300
    In: Journal of Cerebral Blood Flow & Metabolism, SAGE Publications, Vol. 20, No. 9 ( 2000-09), p. 1294-1300
    Abstract: The involvement of caspase-3 in cell death after hypoxia–ischemia (HI) was studied during brain maturation. Unilateral HI was produced in rats at postnatal day 7 (P7), 15 (P15), 26 (P26), and 60 (P60) by a combination of left carotid artery ligation and systemic hypoxia (8% O 2 ). Activation of caspase-3 and cell death was examined in situ by high-resolution confocal microscopy with anti-active caspase-3 antibody and propidium iodide and by biochemical analysis. The active caspase-3 positive neurons were composed of more than 90% HI damaged striatal and neocortical neurons in P7 pups, but that number was reduced to approximately 65% in striatum and 34% in the neocortex of P15 pups, and approximately 26% in striatum and 2% in neocortex of P26 rats. In P60 rats, less than 4% of the damaged neurons in striatum and less than 1% in neocortex were positive for active caspase-3. Western blot analysis demonstrated that the level of inactive caspase-3 in normal forebrain tissue gradually declined from a high level in young pups to very low levels in adult rats. Concomitantly, HI-induced active caspase-3 was reduced from a relatively high level in P7, to moderate levels in P15 and P26, to a barely detectable level in P60 rats. The authors conclude that the involvement of caspase-3 in the pathogenesis of cell death after HI declines during neuronal maturation. The authors hypothesize that caspase-3 may play a major role in cell death in immature neurons but a minor role in cell death in mature neurons after brain injury.
    Type of Medium: Online Resource
    ISSN: 0271-678X , 1559-7016
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2000
    detail.hit.zdb_id: 2039456-1
    detail.hit.zdb_id: 604628-9
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  • 5
    Online Resource
    Online Resource
    SAGE Publications ; 2022
    In:  Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy Vol. 236, No. 6 ( 2022-09), p. 1048-1058
    In: Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy, SAGE Publications, Vol. 236, No. 6 ( 2022-09), p. 1048-1058
    Abstract: The hybrid Voronoi-Latin Hypercube Sampling (Voronoi-LHS) method is proposed for the surrogate-aided optimization of the axial compressor blades. The hybrid method is first applied to the fundamental test cases. The analytical results show that, compared with the Voronoi and LHS strategies, the hybrid method generally improves the robustness and convergency. Then the multi-objective genetic algorithm (MOGA) in conjunction with the artificial neural network (ANN) is applied to optimize the aerodynamic performance of an axial compressor rotor. Before the optimization process, the hybrid Voronoi-LHS sample infilling method is employed to refine the ANN surrogate model. Considering the typical intake distortion, the sweep and lean distributions of this rotor are optimized to pursue the maximum total pressure ratio and adiabatic efficiency. The results show that the optimization significantly improves the pressure ratio, efficiency and surge margin of the compressor with low computing cost.
    Type of Medium: Online Resource
    ISSN: 0957-6509 , 2041-2967
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 1026903-4
    detail.hit.zdb_id: 2024892-1
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  • 6
    In: Polymers and Polymer Composites, SAGE Publications, Vol. 21, No. 8 ( 2013-10), p. 525-532
    Abstract: This study aimed at the development and characterization/evaluation of polyethylene glycol (PEG) encapsulated in supporting polymer matrices (e.g., electrospun nanofibres) as innovative form-stable phase change materials (PCMs) for storage and retrieval of thermal energy. Ultrafine phase change fibres consisting of PEG (acting as phase change materials) and polyamide 6 (PA6, acting as supporting materials) were successfully fabricated by electrospinning technique. The effects of PEG amount and two different molecular weights (M n ) of PEG on structural morphology and thermal energy storage/retrieval property of PEG/PA6 ultrafine phase change fibres were systematically studied by scanning electron microscopy (SEM) and differential scanning calorimetry (DSC), respectively. The SEM images showed that neat PA6 nanofibres were smooth with cylindrical shape, but the tubercles and/or beads in fibres were observed for PEG/PA6 ultrafine phase change fibres with increasing PEG amount and higher molecular weight of PEG. The average fibre diameters ranged from about 80 to 150 nm and increased with increasing the PEG amount and molecular weight of PEG, which resulted from the increased viscosity and decreased conductivity of composite spin dopes. The DSC results indicated that the enthalpies of melting and crystallization of PEG/PA6 ultrafine phase change fibres increased with increasing PEG amount, and were lower than those of neat PEG powders.
    Type of Medium: Online Resource
    ISSN: 0967-3911 , 1478-2391
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 1145951-7
    detail.hit.zdb_id: 2099644-5
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  • 7
    Online Resource
    Online Resource
    SAGE Publications ; 2020
    In:  Journal of Engineered Fibers and Fabrics Vol. 15 ( 2020-01), p. 155892501989894-
    In: Journal of Engineered Fibers and Fabrics, SAGE Publications, Vol. 15 ( 2020-01), p. 155892501989894-
    Abstract: Polyacrylonitrile-based pre-oxidized fibers with improved thermal stability, flame retardant, and mechanical properties were made from the pristine polyacrylonitrile fibers through chemical pretreatment followed by pre-oxidation in air. The morphological structure of the polyacrylonitrile-based pre-oxidized fibers was investigated by Fourier transfer infrared spectra, X-ray diffraction, scanning electron microscopy, and X-ray energy dispersive spectrometer. The changes of characteristic functional groups and chemical compositions confirmed the successful modification of the polyacrylonitrile fibers during pre-treatment. The grooves and cracks on the surface of polyacrylonitrile-based pre-oxidized fibers were remarkably decreased in comparison with that of pristine polyacrylonitrile fibers. The evolution of crystalline structure of the polyacrylonitrile fibers proved the occurrence of cyclization reactions during pre-oxidation. Meanwhile, thermal stability, flame retardant, and mechanical properties of polyacrylonitrile-based pre-oxidized fibers were also investigated by thermogravimetric analyzer, oxygen index meter, micro combustion calorimeter, and single fiber tensile tester, respectively. The results demonstrated that the polyacrylonitrile-based pre-oxidized fibers initially pre-treated by hydroxylamine hydrochloride, followed by monoethanolamine, had a high limiting oxygen index of 40.1 and breaking strength of 2.03 cN/dtex. The peak of heat release rate and total heat release of polyacrylonitrile-based pre-oxidized fibers decreased significantly while its charred residues increased, contributing to the improved flame retardant property.
    Type of Medium: Online Resource
    ISSN: 1558-9250 , 1558-9250
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2393988-6
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  • 8
    Online Resource
    Online Resource
    SAGE Publications ; 2024
    In:  Advances in Mechanical Engineering Vol. 16, No. 5 ( 2024-05)
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 16, No. 5 ( 2024-05)
    Abstract: Dynamic analysis is a key problem of flywheel energy storage system (FESS). In this paper, a one-dimensional finite element model of anisotropic composite flywheel energy storage rotor is established for the composite FESS, and the dynamic characteristics such as natural frequency and critical speed are calculated. Through the analysis of acceleration transient response, it is found that the flywheel rotor have two critical speeds during acceleration or deceleration process, which are prone to resonance and damage the bearing. Therefore, in order to avoid resonance or reduce resonance peak, the influence of bearing support stiffness, damping and speed-up rate on the critical speed and resonance peak is studied. The calculation results show that the first two order critical speed are affected by the support stiffness. When the stiffness increases, the critical speed of the flywheel rotor increases, but the growth rate decreases. When the damping increases, the critical speed is basically not affected, and the vibration amplitude decreases rapidly. In addition, the resonance peak value of transient response can be effectively reduced by increasing the speed-up rate.
    Type of Medium: Online Resource
    ISSN: 1687-8132 , 1687-8140
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2024
    detail.hit.zdb_id: 2501620-9
    detail.hit.zdb_id: 2770853-6
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  • 9
    Online Resource
    Online Resource
    SAGE Publications ; 2015
    In:  Advances in Mechanical Engineering Vol. 7, No. 3 ( 2015-03-01), p. 168781401557543-
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 7, No. 3 ( 2015-03-01), p. 168781401557543-
    Abstract: There have been many reports recently on unanticipated galloping and collapse accidents of tower-line systems due to downburst wind with rainfall. Although wet downburst is characterized by high-velocity wind with rainfall, very little research work is involved with galloping of high-voltage transmission line induced by the downburst wind with rainfall. Thus, this article proposes a preliminary theoretical study aiming to provide an analytical model of the high-voltage transmission line subjected to the downburst wind with rainfall to explain some phenomena observed from field measurements. Through wind or rain–wind tunnel experiments, we obtained aerodynamic characteristics of the high-voltage conductor with different yaw angles and rainfall rates. Considering the variations of several factors such as wind velocity, rainfall rate, yaw angle, and attack angle, the proposed analytical model was created by finite element method and central differences with the obtained aerodynamic coefficients of the high-voltage conductor. The theoretical results accord well with the experimental data. The analytical model enables better comprehension of the galloping of the high-voltage transmission line subjected to the downburst wind with rainfall.
    Type of Medium: Online Resource
    ISSN: 1687-8140 , 1687-8140
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2501620-9
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  • 10
    Online Resource
    Online Resource
    SAGE Publications ; 2014
    In:  Advances in Mechanical Engineering Vol. 6 ( 2014-01-01), p. 638653-
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 6 ( 2014-01-01), p. 638653-
    Abstract: Under rainfall conditions, rain-wind induced vibration occurs on high-voltage transmission line occasionally. This phenomenon is caused by raindrops hitting the high-voltage conductor with a certain velocity and suspends to the bottom surface of the high-voltage conductor. By action of wind velocity and high-voltage conductor's motion, some suspended raindrops will be blown away or shaken off. The remaining water may be reformed as upper rivulet and lower rivulet. Like the effect of icing galloping, this type of vibration can cause metal fatigue on fittings and towers, while its mechanism remains unknown. The objective of this paper is to validate an analytical model of rain-wind induced vibration of the high-voltage transmission line and to investigate the effect of wind velocity, rivulet motion, raindrop velocity, and time varying mass on the vibration amplitude. Taking Tuo-chang transmission line as an example, the analytical model is solved by Galerkin weighted residual method and central difference method. The numerical results are in agreement with the experimental data available in the literature. The analytical model enables more comprehensive understanding of the rain-wind induced vibration mechanism.
    Type of Medium: Online Resource
    ISSN: 1687-8140 , 1687-8140
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2501620-9
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