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  • SAGE Publications  (30)
  • 1
    Online Resource
    Online Resource
    Validation and comparison of multiple risk scores for prediction of symptomatic intracerebral hemorrhage after intravenous thrombolysis in VISTA
    SAGE Publications ; 2023
    In:  International Journal of Stroke Vol. 18, No. 3 ( 2023-03), p. 338-345
    Details
    In: International Journal of Stroke, SAGE Publications, Vol. 18, No. 3 ( 2023-03), p. 338-345
    Abstract: Prediction models/scores may help to identify patients at high risk of symptomatic intracerebral hemorrhage (sICH) after intravenous thrombolysis. We aimed to validate and compare the performance of different prediction models for sICH after thrombolysis using direct model estimation in the Virtual International Stroke Trials Archive (VISTA). Methods: We searched PubMed for potentially eligible prediction models from inception to 1 June 2019. Simple and practical models/scores were validated in VISTA. The primary outcome was sICH based on two criteria (National Institute of Neurological Diseases and Stroke, NINDS; Safe Implementation of Thrombolysis in Stroke-Monitoring Study, SITS-MOST) and the secondary outcome was parenchymal hematoma (PH). The discrimination performance of each model was evaluated using area under the curve (AUC) and calibration was evaluated by Hosmer–Lemeshow goodness-of-fit tests. Results: We found 13 prediction models and five models (HAT, MSS, SPAN-100, GRASPS and THRIVE) were finally validated in VISTA. A total of 1884 participants were eligible for our study, of whom the proportion with sICH was 4.6% (87/1884) per NINDS and 3.9% (73/1884) per SITS-MOST, and with PH was 11.3% (213/1884). MSS and GRASPS had the greatest predictive ability for sICH (NINDS criteria: MSS AUC 0.7, 95% CI 0.63–0.77, p  〈  0.001; GRASPS AUC 0.69, 95% CI 0.63–0.76, p  〈  0.001; SITS-MOST criteria: MSS, AUC 0.76, 95% CI 0.68–0.85, p  〈  0.001; GRASPS, AUC 0.79, 95% CI 0.71–0.87, p  〈  0.001). Similar results were found for PH (MSS AUC 0.68, 95% CI 0.64–0.73, p = 0.017; GRASPS AUC 0.68, 95% CI 0.63–0.72, p = 0.017). The calibration of each model was almost good. Conclusion: MSS and GRASPS had good discrimination and calibration for sICH and PH after thrombolysis as assessed in VISTA. These two models could be used in clinical practice and clinical trials to identity individuals with high risk of sICH.
    Type of Medium: Online Resource
    ISSN: 1747-4930 , 1747-4949
    URL: Article
    DOI: 10.1177/17474930221106858
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2211666-7
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  • 2
    Online Resource
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    Premonitory symptoms in migraine from China: A multi-clinic study of 4821 patients
    SAGE Publications ; 2021
    In:  Cephalalgia Vol. 41, No. 9 ( 2021-08), p. 991-1003
    Details
    In: Cephalalgia, SAGE Publications, Vol. 41, No. 9 ( 2021-08), p. 991-1003
    Abstract: To observe the prevalence and characteristics of premonitory symptoms in Chinese migraineurs and explore their associations with migraine-related factors. Method Migraineurs who visited a tertiary headache clinic and one of nine neurology clinics between May 2014 and November 2019 were studied. Result Among the 4821 patients meeting the migraine criteria (International Classification of Headache Disorders, 3rd edition), 1038 (21.5%) patients experienced at least one premonitory symptom. The most common premonitory symptoms were neck stiffness, dizziness, yawning and drowsiness. The logistic regression analysis demonstrated that aura, photophobia, aggravation by routine physical activity, triggers, family history, depression, coffee consumption and physical exercise were associated with an increased probability of experiencing premonitory symptoms ( p ≤ 0.001). The premonitory symptoms of migraine with and without aura differ in prevalence and most common symptoms. The cluster analysis revealed pairwise clustering of the following premonitory symptoms: Photophobia/phonophobia, concentration change/dysesthesia, loquacity/overactivity, yawning/drowsiness, fatigue/dizziness, and mood change/irritability. The correlation analysis of triggers and premonitory symptoms revealed that temperature change, environment change, sleep disorder, activity and stress were related to multiple premonitory symptoms, and that food, light, menstruation, alcohol and odor were related to special premonitory symptoms ( p ≤ 0.001). Conclusion The prevalence of premonitory symptoms among migraineurs in China is 21.5%. Some factors influence the probability of experiencing premonitory symptoms. Paired premonitory symptoms in the clustering analysis may share similar origins. Certain triggers associated with multiple premonitory symptoms may induce brain dysfunction; however, other triggers that overlap with corresponding special premonitory symptoms may be premonitory symptoms or a form of premonitory symptom.
    Type of Medium: Online Resource
    ISSN: 0333-1024 , 1468-2982
    URL: Article
    DOI: 10.1177/0333102421997850
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2019999-5
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  • 3
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    Online Resource
    Propagation modeling and performance analysis of intelligent drilling communication system based on capacitance coupling approach
    SAGE Publications ; 2018
    In:  SIMULATION Vol. 94, No. 5 ( 2018-05), p. 421-431
    Details
    In: SIMULATION, SAGE Publications, Vol. 94, No. 5 ( 2018-05), p. 421-431
    Abstract: A new type of intelligent drilling communication system is proposed based on capacitance coupling in order to realize signal transmission in the downhole environment. A system model is established and the dispersion equation is derived. Group velocity, propagation constant, attenuation factor, and the terminal matching condition of the system are discussed according to theoretical derivations. Simulations of a large number of drill pipe units in the time domain, based on the fourth-order Runge–Kutta method, are described to verify the mathematical derivations. An experimental system of lumped parameter components has been established, which verifies the effectiveness of the simulation. Analytical and simulation results show that the carrier frequency can be as high as 0.843 MHz, and that the bandwidth of the proposed system can reach up to about 406 kHz. The results can provide a theoretical basis and comprehensive design guidance for the frequency, communication rate, and bandwidth budget of intelligent drilling communication systems.
    Type of Medium: Online Resource
    ISSN: 0037-5497 , 1741-3133
    URL: Article
    DOI: 10.1177/0037549717737165
    RVK:
    SA 7910
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2072208-4
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  • 4
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    Pulmonary artery flotation catheter (PAFC) combined with pump-controlled retrograde trial off (PCRTO) as a trial for weaning VA-ECMO patients: A retrospective study
    SAGE Publications ; 2023
    In:  Perfusion Vol. 38, No. 2 ( 2023-03), p. 346-352
    Details
    In: Perfusion, SAGE Publications, Vol. 38, No. 2 ( 2023-03), p. 346-352
    Abstract: Pump-controlled retrograde trial off (PCRTO) has been recently proposed as an effective and safe VA-ECMO weaning method. However, reports of haemodynamic monitoring during PCRTO are rare. Therefore, the purpose of this study was to investigate the changes in the left and right heart function during the PCRTO process combined with a pulmonary artery flotation catheter (PAFC). Methods Between March 2019 and May 2021, 20 adult VA-ECMO patients who underwent PCRTO in combination with PAFC were enrolled in this study. The patients' general characteristics, PCRTO results, haemodynamic parameters during PCRTO progression, complications, and clinical prognoses were analysed. Those who survived for 48 h after withdrawal and did not require ECMO assistance were defined as the success group, and those who did not survive for 48 h after withdrawal or who required ECMO assistance were defined as the failure group. Results Of the 20 patients, 13 (65%) were included in the success group, and 7 (35%) were included in the failure group. Compared with the success group, the heart rate (HR) of the failure group was significantly increased 30 min after PCRTO ( p 〈 .01), and the pulmonary artery wedge pressure (PAWP) was significantly higher at all time points ( p 〈 .01). Compared with pre-PCRTO in the success group, the HR at 2 min in the success group was significantly increased, but decreased to the baseline levels at 15 min and 30 min. The PAWP was also significantly increased at 2 min, but decreased at 15 min and dropped to the baseline level at 30 min in the success group. Compared with pre-PCRTO in the failure group, the HR and PAWP increased significantly at 2 min, 15 min and 30 min in the failure group. No new embolism-related complications were found in the success group after the withdrawal from ECMO. Conclusions PCRTO is a safe and reliable VA-ECMO weaning method. Combined with haemodynamic monitoring through PAFC, PCRTO can better assess the cardiac reserve function.
    Type of Medium: Online Resource
    ISSN: 0267-6591 , 1477-111X
    URL: Article
    DOI: 10.1177/02676591211054976
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2029611-3
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  • 5
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    Machine learning approach to improve vapor recovery: Prediction and frequency converter with a new vapor recovery system
    SAGE Publications ; 2022
    In:  Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science Vol. 236, No. 5 ( 2022-03), p. 2079-2088
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science, SAGE Publications, Vol. 236, No. 5 ( 2022-03), p. 2079-2088
    Abstract: In practice, the volatile organic compounds (VOCs) pollution can exist when refueling due to the properties of the gasoline, low viscosity and high saturated-vapor pressure. A new gasoline vapor recovery system involving frequency conversion technology and machine learning is developed to cope with this problem. In the proposed system, firstly, the pumping capacity of the vacuum pump is evaluated, and test shows an almost linear relationship between suction volume and frequency. Then, the Multi-Layer Perception (MLP) neural network and the support vector regression (SVR) are employed to predict the gas-liquid ratio, and the numerical examples are presented to prove the high prediction accuracy of the MLP and SVR, respectively, where the MLP neural network has better generalization ability. Finally, compared with the two gasoline vapor recovery systems based on the 1: 1 fixed control model and the PID control model, respectively, the gasoline vapor recovery efficiency is improved significantly by the new gasoline vapor recovery system.
    Type of Medium: Online Resource
    ISSN: 0954-4062 , 2041-2983
    URL: Article
    DOI: 10.1177/09544062211027199
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2024890-8
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  • 6
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    WeChat-based mobile health management for short-stature children with long-term growth hormone therapy: A nonexperimental study
    SAGE Publications ; 2023
    In:  DIGITAL HEALTH Vol. 9 ( 2023-01), p. 205520762311798-
    Details
    In: DIGITAL HEALTH, SAGE Publications, Vol. 9 ( 2023-01), p. 205520762311798-
    Abstract: To evaluate the role of a WeChat-based mobile platform in growth hormone therapy. Method Growth hormone therapy and health education information for height growth were embedded in a WeChat-based mobile platform, and the platform was evaluated through medical staff assessments, patient volunteer assessments and quantitative scoring criteria. Results In the medical staff evaluation, both clinicians and nurses had a positive attitude towards the mobile platform, believing that the design of the mobile platform was clearly visualized and easy to operate. In family volunteers’ evaluations, the summary of β-testing results showed that 90–100% of parents had a positive attitude towards the WeChat-based mobile platform. Parents of the patients and doctors and nurses assessed the mobile platform by reviewing quantitative scoring standards developed by professional researchers. All scores were 〉 16 (the average score was 18–19.3). Children treated with growth hormone therapy were included for compliance tracking for one year, and patient adherence was described in this study. Conclusion The interaction based on the WeChat platform and the health education of the public have greatly increased the interaction between doctors and patients, and improved patient satisfaction and compliance.
    Type of Medium: Online Resource
    ISSN: 2055-2076 , 2055-2076
    URL: Article
    DOI: 10.1177/20552076231179849
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2819396-9
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  • 7
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    Dynamic modelling of a rotor-bearing-housing system including a localized fault
    SAGE Publications ; 2018
    In:  Proceedings of the Institution of Mechanical Engineers, Part K: Journal of Multi-body Dynamics Vol. 232, No. 3 ( 2018-09), p. 385-397
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part K: Journal of Multi-body Dynamics, SAGE Publications, Vol. 232, No. 3 ( 2018-09), p. 385-397
    Abstract: An in-depth understanding of the dynamic characteristics through rotor-bearing-housing systems is very valuable for fault detection and diagnosis applications of rotating machines such as high-speed spindle, roll mill, gearbox, engines, etc. A new vibration model of a rotor-bearing-housing system considering the rotor compliance, elastic interface between the housing and outer race, housing compliance, and time-dependent excitations introduced by a localized fault on the inner and outer races of an inherent ball bearing is proposed in this work. An analytical method for calculating the time-dependent excitations including the time-dependent displacement excitation and contact stiffness coefficient between the ball and fault edges is presented. Differences between vibration responses of a rotor-bearing-housing system from the proposed model and the previous model without the rotor compliance in the literature are discussed. The presented model is used to discuss the influences of all the rotor compliance, housing compliance, and fault sizes on the races of the inherent ball bearing on the vibration responses and vibration transmission characteristics through the rotor-bearing-housing system, which cannot be formulated by the current dynamic models in the listed references. An experimental study is introduced to validate the presented model. The results show that the rotor compliance and time-dependent contact stiffness coefficient caused by the fault have great influence on the dynamic characteristics through the rotor-bearing-housing system. It also seems that the developed method can provide a new vibration modelling method for the vibration analysis for a rotor-bearing-housing system with and without the faults.
    Type of Medium: Online Resource
    ISSN: 1464-4193 , 2041-3068
    URL: Article
    DOI: 10.1177/1464419317738427
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2032771-7
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  • 8
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    Evaluation of the anti-angiogenic effect of bevacizumab on rat C6 glioma by spectral computed tomography
    SAGE Publications ; 2021
    In:  Acta Radiologica Vol. 62, No. 1 ( 2021-01), p. 120-128
    Details
    In: Acta Radiologica, SAGE Publications, Vol. 62, No. 1 ( 2021-01), p. 120-128
    Abstract: Anti-angiogenic drugs have become a research hotspot in recent years. However, dynamically observing their therapeutic effect at different time points during treatment is a clinical problem. Purpose To explore the feasibility of the quantitative parameters of spectral computed tomography (CT) in evaluating the anti-angiogenic effect of bevacizumab on rat C6 glioma. Material and Methods Twenty-six male Sprague-Dawley rats were used to establish the C6 glioma model. The rats were randomly divided into the experimental group (n = 13) and control group (n = 13). The experimental group was intraperitoneally injected with 0.2 µL/g bevacizumab every day, whereas the control group was injected with the same dose of normal saline every day for one week. Spectral CT scanning was performed on the 4th and 8th days after treatment; meanwhile, the brain tissues were collected by heart perfusion for H & E staining, and VEGF and HIF-1α immunohistochemical staining. Results On the 4th and 8th days, significant differences in the 70-keV single-energy CT value, slope of the energy spectrum curve, and iodine concentration were found between the experimental group and the control group. Correlation analysis between immunohistochemistry and quantitative parameters of spectral CT showed that the single energy CT value of 70 keV, slope of the energy spectrum curve, and concentration of iodine were positively correlated with VEGF and HIF-1α at different time points in the experimental group and the control group. Conclusion Spectral CT multi-parameter imaging can be employed as a new method to evaluate the anti-angiogenic effect of bevacizumab on rat C6 glioma.
    Type of Medium: Online Resource
    ISSN: 0284-1851 , 1600-0455
    URL: Article
    DOI: 10.1177/0284185120916200
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2024579-8
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  • 9
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    The effect of a localized fault in the planet bearing on vibrations of a planetary gear set
    SAGE Publications ; 2018
    In:  The Journal of Strain Analysis for Engineering Design Vol. 53, No. 5 ( 2018-07), p. 313-323
    Details
    In: The Journal of Strain Analysis for Engineering Design, SAGE Publications, Vol. 53, No. 5 ( 2018-07), p. 313-323
    Abstract: Dynamic characteristics of a planetary gear set can be greatly affected by a localized fault in the planet bearing. To understand the relationship between the dynamic characteristic of the planetary gear set and the localized fault sizes, a dynamic finite element model for a planetary gear set is developed. A localized fault is assumed to be located in the outer race of the planet bearing. The fault profile is defined as a rectangular one. To formulate the elastic deformations of the components and elastic contact deformations between the mating components, all components of the planetary gear set are considered as elastic bodies in the finite element model. A standard gravity is also considered in the finite element model. A Coulomb frictional model is used to formulate the frictional forces in the planetary gear set. Influences of the rotational velocity, moment, and fault width on the dynamic characteristics of the planetary gear set are discussed. The simulation results are compared with those from the previous method to validate the finite element model. It seems that the presented finite element model can be applied to simulate the dynamic characteristics of a planetary gear set caused by a localized fault in the outer race of the planet bearing.
    Type of Medium: Online Resource
    ISSN: 0309-3247 , 2041-3130
    URL: Article
    DOI: 10.1177/0309324718769491
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2015328-4
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  • 10
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    Evaluation of stability of deep venous thrombosis of the lower extremities using Doppler ultrasound
    SAGE Publications ; 2020
    In:  Journal of International Medical Research Vol. 48, No. 8 ( 2020-08), p. 030006052094209-
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 48, No. 8 ( 2020-08), p. 030006052094209-
    Abstract: This study aimed to assess using Doppler ultrasound for analyzing stability of deep venous thrombosis (DVT) of the lower extremities. Methods Patients with DVT of the lower extremities who were treated from August 2017 to December 2019 were selected. The patients were divided into stable and unstable groups according to whether thrombus was collected in a filter. Related ultrasound and blood test results were analyzed and compared. Results A total of 126 patients with DVT of the lower extremities were included, of whom 74 were in the stable group and 52 were in the unstable group. There were significant differences in the prothrombin time (PT), and lipoprotein alpha, D-dimer, and triglyceride levels between the groups. D-dimer levels 〉 2800 ug/L, smoking, history of venous thrombosis, PT 〉 13.15 s, and body mass index 〉 24.45 kg/m 2 were independent risk factors for stability of DVT of the lower extremities. The area under the curve with combined detection of DVT was significantly higher than that for body mass index, PT, and D-dimer alone. Conclusion Doppler ultrasound may be reliable for analyzing the stability of DVT of the lower extremities. Related strategies targeting risk factors are required for reducing DVT of the lower extremities.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/0300060520942098
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2082422-1
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