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  • 1
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    Setting up a regional health system database for seamless population health management in Singapore
    SAGE Publications ; 2016
    In:  Proceedings of Singapore Healthcare Vol. 25, No. 1 ( 2016-03), p. 27-34
    Details
    In: Proceedings of Singapore Healthcare, SAGE Publications, Vol. 25, No. 1 ( 2016-03), p. 27-34
    Abstract: Understanding the health and health service utilization of the population is critical for Regional Health System’s (RHS) population health management (PHM) initiatives in Singapore. The RHS database is a collaborative effort toward developing a national architecture for healthcare utilization data across diverse clinical systems with disparate data models. This manuscript describes the setup of an RHS database which would facilitate big data analytics for proactive population health management and health services research. Materials and methods: The RHS database is a conglomeration of four isolated databases from the three RHSs. It contains linked National Healthcare Group (NHG) polyclinic visit records, specialist outpatient clinic visit records, hospital discharge records from Tan Tock Seng Hospital (TTSH), National University Hospital (NUH) and Alexandra Hospital (AH), chronic disease management system (CDMS) records and mortality records from local registries. The data linkage process was conducted using the unique identification number (NRIC) as the linking variable. The final anonymized database has multiple interconnected tables that includes patient demographics, chronic disease and healthcare utilization information. Results: Over 2.8 million patients had contact with the three RHSs from 2008 to 2013. The database facilitated risk stratification of patients based on their past healthcare utilization and chronic disease information. This database aids in understanding the cross-utilization of healthcare services across the three RHSs and can help address the challenges of setting up a distinct geographical boundary for individual RHSs. Conclusions: The RHS database has been established with the intention to support the secondary use of administrative health data in health services research and proactive PHM in Singapore.
    Type of Medium: Online Resource
    ISSN: 2010-1058 , 2059-2329
    URL: Article
    DOI: 10.1177/2010105815611440
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2831421-9
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  • 2
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    Monitoring early response of lymph node metastases to radiotherapy in animal models: diffusion-weighted imaging vs. morphological MR imaging
    SAGE Publications ; 2011
    In:  Acta Radiologica Vol. 52, No. 9 ( 2011-11), p. 989-994
    Details
    In: Acta Radiologica, SAGE Publications, Vol. 52, No. 9 ( 2011-11), p. 989-994
    Abstract: Diffusion-weighted imaging (DWI) offers a non-invasive technique that can reveal microscopic details about the architecture of both normal and anomalous tissues. Some studies have confirmed DWI can detect the early changes of tumors that have originated from various organs, even after treatment. Purpose To compare the usefulness of apparent diffusion coefficient (ADC) and morphologic magnetic resonance (MR) imaging for monitoring the therapeutic response of metastatic disease in lymph nodes to radiotherapy. Material and Methods Twenty-six rabbits (metastatic, n = 17; non-metastatic, n = 9) were divided into group A (metastatic, n = 10), group B (metastatic, n = 7) and group C (non-metastatic, n = 9). Groups A and C underwent irradiation, whereas group B was set as a reference. Standard MR imaging and DWI were performed before and 1, 3, and 7 days after radiotherapy for all rabbits. The lymph node volumes and ADCs were measured and evaluated with repeated measures ANOVA. The difference between group A and B was analyzed using Student's t-test. Results In all rabbits, a total of 35 lymph nodes were found, including 16 nodes in group A, 10 in group B and nine in group C. In group A, 3 and 7 days after therapy ADCs were significantly higher than pre-treatment and 1 day after therapy ( P 〈 0.05). For groups A and B, a significant difference of ADCs was present 7 days after therapy. A significant difference of variation of ADCs among the three groups was also present ( P 〈 0.001). Conclusion DWI is superior to morphological MRI in monitoring early radiation response in animal models.
    Type of Medium: Online Resource
    ISSN: 0284-1851 , 1600-0455
    URL: Article
    DOI: 10.1258/AR.2011.110254
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2011
    detail.hit.zdb_id: 2024579-8
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  • 3
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    Binary structured polypropylene-/propylene-based elastomer fibrous membranes with enhanced flexibility
    SAGE Publications ; 2022
    In:  Journal of Industrial Textiles Vol. 51, No. 9 ( 2022-04), p. 1431-1444
    Details
    In: Journal of Industrial Textiles, SAGE Publications, Vol. 51, No. 9 ( 2022-04), p. 1431-1444
    Abstract: Polypropylene (PP) fibrous membranes are widely used in medical and healthcare due to its sustainability. However, pristine PP fibrous membranes show poor flexibility, which limits their advanced functional application in medical and healthcare. Therefore, to improve the flexibility of PP fibrous membranes, propylene-based elastomer (PBE), a copolymer compatible with PP, was introduced by using the melt blowing technique in this study. The SEM images show that the PP/PBE fibrous membrane samples expressed a binary structured network morphology consisting of fibers with a diameter distribution ranging from 0.4 to 15 µm. With an increase in PBE mass ratio from 15 to 80 wt%, the frequency of fibers with a diameter 〈 3 µm increased from 48.6 to 61.2%, thus making the elastic recovery rate in the machine direction (MD) increase from 62.9 to 80.3% and softness values increase from 15.88 to 54.31. Meanwhile, air permeability increased from 856 to 2257 m 3 /m 2  · h as the mass per unit area of the samples decreased from 129.9 to 40.1 g/m 2 . This work provides an alternate method for producing flexible fibrous membranes that have potential for application in items such as surgical gown cuffs, bandages, and face mask ear loops.
    Type of Medium: Online Resource
    ISSN: 1528-0837 , 1530-8057
    URL: Article
    DOI: 10.1177/1528083720903041
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2095351-3
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  • 4
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    Cilostazol Enhances Mobilization of Circulating Endothelial Progenitor Cells and Improves Endothelium-Dependent Function in Patients at High Risk of Cardiovascular Disease
    SAGE Publications ; 2016
    In:  Angiology Vol. 67, No. 7 ( 2016-08), p. 638-646
    Details
    In: Angiology, SAGE Publications, Vol. 67, No. 7 ( 2016-08), p. 638-646
    Abstract: This is the first study to investigate the vasculoangiogenic effects of cilostazol on endothelial progenitor cells (EPCs) and flow-mediated dilatation (FMD) in patients at high risk of cardiovascular disease (CVD). This double-blind, placebo-controlled study included 71 patients (37 received 200 mg/d cilostazol and 34 received placebo for 12 weeks). Use of cilostazol, but not placebo, significantly increased circulating EPC (kinase insert domain receptor + CD34 + ) counts (percentage changes: 149.0% [67.9%-497.8%] vs 71.9% [−31.8% to 236.5%] , P = .024) and improved triglyceride and high-density lipoprotein cholesterol levels ( P = .002 and P = .003, respectively). Plasma levels of vascular endothelial growth factor (VEGF)-A165 and FMD significantly increased (72.5% [32.9%-120.4%] vs −5.8% [−46.0% to 57.6%] , P = .001; 232.8% ± 83.1% vs −46.9% ± 21.5%, P = .003, respectively) in cilostazol-treated patients. Changes in the plasma triglyceride levels significantly inversely correlated with the changes in the VEGF-A165 levels and FMD. Cilostazol significantly enhanced the mobilization of EPCs and improved endothelium-dependent function by modifying some metabolic and angiogenic markers in patients at high risk of CVD.
    Type of Medium: Online Resource
    ISSN: 0003-3197 , 1940-1574
    URL: Article
    DOI: 10.1177/0003319715606249
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2065911-8
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  • 5
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    Intra-Operative Fractures in Cementless Bipolar Hemiarthroplasty
    SAGE Publications ; 2015
    In:  Journal of Orthopaedic Surgery Vol. 23, No. 2 ( 2015-08), p. 218-222
    Details
    In: Journal of Orthopaedic Surgery, SAGE Publications, Vol. 23, No. 2 ( 2015-08), p. 218-222
    Abstract: To compare patients with or without intra-operative fracture during cementless bipolar hemiarthroplasty. Methods. Records of 76 men and 202 women who underwent cementless bipolar hemiarthroplasty for femoral neck fractures were reviewed. Patients with and without intra-operative fractures and patients with different types of intra-operative fractures were compared. Results. Two men and 22 women aged 62 to 93 (mean, 80) years sustained intra-operative fractures at the lesser trochanter (n=18), the greater trochanter (n=5), and the subtrochanter (n=1). All 18 lesser trochanteric fractures and 4 of the greater trochanteric fractures were recognised intra-operatively and managed with cerclage wiring (n=21) or conversion to cemented hemiarthroplasty with cerclage wiring (n=1). The remaining 2 fractures were recognised postoperatively on radiographs and managed conservatively or with revision surgery and cerclage wiring and plating on day 4. Intra-operative fractures correlated with female gender (p=0.03) and operative delay to optimise patients (p=0.02), whereas the fracture site correlated with the time of fracture recognition (p=0.01). Postoperatively, 5 patients were allowed partial weight bearing and 18 were instructed to mobilise with a wheelchair for at least 6 weeks. One patient died from an unrelated cause. At one year, 21 patients reported no hip pain and 2 reported minimal pain. 17 could walk with or without aids and 6 were wheelchair-bound. Conclusion. Surgeons should be familiar with the size difference in trial and actual implants used in bipolar hemiarthroplasty in order to better estimate the extent of broaching required. In most patients with an intra-operative fracture, the one-year outcome was not compromised, despite the poorer short-term outcome.
    Type of Medium: Online Resource
    ISSN: 2309-4990 , 2309-4990
    URL: Article
    DOI: 10.1177/230949901502300222
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2128854-9
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  • 6
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    A Pilot Study of a Traditional Chinese Version of the University of Pennsylvania Smell Identification Test for Application in Taiwan
    SAGE Publications ; 2010
    In:  American Journal of Rhinology & Allergy Vol. 24, No. 1 ( 2010-01), p. 45-50
    Details
    In: American Journal of Rhinology & Allergy, SAGE Publications, Vol. 24, No. 1 ( 2010-01), p. 45-50
    Abstract: The 40-item University of Pennsylvania Smell Identification Test (UPSIT) is the most widely used smell test in the world. Presently, culturally modified versions of this test are available in 12 languages. This study describes the first assessment of a prototype traditional Chinese version of the UPSIT (UPSIT-TC) for administration in Taiwan. The goals were to determine the efficacy of specific items for testing Taiwanese subjects and to establish normative adjustments to allow for the use of North American norms. Methods The American version of the UPSIT and the UPSIT-TC were administered to 40 healthy Taiwanese subjects on two test occasions separated from one another by 2 weeks. One subject was excluded because of invalid data. Results The mean UPSIT score was 28.3 (median, 28; SD, 3.8) for the first test administration and 28.5 (median, 28.0; SD, 4.4) for the second test administration. The mean UPSIT-TC score was 33.1 (median, 33.0; SD, 2.9) for the first administration and 32.8 (median, 33.0; SD, 3.6) for the second test administration. The UPSIT-TC scores were significantly higher than those of the UPSIT on both test occasions (p 〈 0.0001). Pearson correlations computed across the two test occasions were positive and statistically significant for both the UPSIT and the UPSIT-TC (respectively, r = 0.803 and 0.664; p 〈 0.0001). Conclusions In accord with the modifications, the scores on the prototype UPSIT-TC were significantly higher than those on the American UPSIT when administered to a Taiwanese sample. Both versions of the UPSIT were stable across repeated test sessions.
    Type of Medium: Online Resource
    ISSN: 1945-8924 , 1945-8932
    URL: Article
    DOI: 10.2500/ajra.2010.24.3388
    RVK:
    XA 20278
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2010
    detail.hit.zdb_id: 2554548-6
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  • 7
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    Validation of the Applicability of the Traditional Chinese Version of the University of Pennsylvania Smell Identification Test in Patients with Chronic Rhinosinusitis
    SAGE Publications ; 2014
    In:  Allergy & Rhinology Vol. 5, No. 1 ( 2014-01), p. ar.2014.5.0084-
    Details
    In: Allergy & Rhinology, SAGE Publications, Vol. 5, No. 1 ( 2014-01), p. ar.2014.5.0084-
    Abstract: The 40-item University of Pennsylvania Smell Identification Test (UPSIT) is the most widely used smell test in the world. Presently, culturally modified versions of this test are available in multiple languages. A traditional Chinese version of the UPSIT (UPSIT-TC) has been developed for administration in Taiwan. The purpose of this study was to investigate the validity and reliability of the UPSIT-TC in Taiwanese patients with chronic rhinosinusitis (CRS). The phenylethyl alcohol (PEA) odor detection threshold test, the North American version of UPSIT (UPSIT-NA), and the UPSIT-TC were administered to 40 healthy subjects and to 100 CRS patients before and after functional endoscopic sinus surgery (FESS). The UPSIT-TC showed good internal consistency (Cronbach's alpha = 0.887, 0.886, and 0.870 at three test occasions) and test-retest reliability (p 〈 0.001). The scores of UPSIT-TC were significantly correlated to the PEA thresholds (p 〈 0.001). The UPSIT-TC scores were significantly higher than those of the UPSIT-NA (p = 0.028) when analysis was performed with logistic regression with independent variables including test occasions (before or after FESS), test methods (UPSIT-NA or UPSIT-TC), status of polyp (with or without), and PEA thresholds (improved or did not improve). In addition, there were significant between-group differences in UPSIT-TC scores including healthy versus CRS, CRS with polyps versus CRS without polyps, and PEA thresholds improved versus PEA thresholds which did not improve. The UPSIT-TC is reliable and valid for measuring olfactory function in Taiwanese patients with rhinosinusitis. In addition, the UPSIT-TC clearly resulted in better performance than that of UPSIT-NA.
    Type of Medium: Online Resource
    ISSN: 2152-6567 , 2152-6567
    URL: Article
    DOI: 10.2500/ar.2014.5.0084
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 3162459-5
    detail.hit.zdb_id: 2675684-5
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  • 8
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    Dynamic compensation control strategy of DC bus voltage based on residual generator
    SAGE Publications ; 2021
    In:  Science Progress Vol. 104, No. 2 ( 2021-04), p. 003685042110262-
    Details
    In: Science Progress, SAGE Publications, Vol. 104, No. 2 ( 2021-04), p. 003685042110262-
    Abstract: Aiming at the problem of bus voltage control in DC microgrid, a dynamic compensation control strategy based on a residual generator is designed to complete the voltage compensation of DC-DC converter. Firstly, based on the DC microgrid system architecture, the bus voltage fluctuations are analyzed theoretically, and then the DC-DC converter state-space mathematical models of the DC microgrid system are established to obtain the input-output relationship of the control system. Based on the theory of double coprime decomposition and Youla parameterization stable controller, the proposed control architecture based on the residual generator is obtained, and the output value generated by the current disturbance is compensated in reverse by applying model matching theory. The voltage loop compensation controller Q( s) is obtained by the linear matrix inequality method (LMI), and the current loop compensation controller H( s) is designed according to the dynamic structure diagram of the DC-DC converter. Hardware-in-the-loop simulation (HILS) results show that the architecture can improve the dynamic performance of the DC-DC converter without changing the original system structure parameters, and suppress the DC bus voltage fluctuations caused by load switching, power fluctuations, and AC-side load imbalances, and enhance the robustness of the system.
    Type of Medium: Online Resource
    ISSN: 0036-8504 , 2047-7163
    URL: Article
    DOI: 10.1177/00368504211026284
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2483680-1
    detail.hit.zdb_id: 2199376-2
    SSG: 11
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  • 9
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    Multilayer hierarchical control for robotic coax-helicopter based on the H ∞ robustness and mixing control scheme
    SAGE Publications ; 2017
    In:  Advances in Mechanical Engineering Vol. 9, No. 10 ( 2017-10), p. 168781401772008-
    Details
    In: Advances in Mechanical Engineering, SAGE Publications, Vol. 9, No. 10 ( 2017-10), p. 168781401772008-
    Type of Medium: Online Resource
    ISSN: 1687-8140 , 1687-8140
    URL: Article
    DOI: 10.1177/1687814017720088
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2501620-9
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  • 10
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    Fault diagnostic strategy of multivalued attribute system based on growing algorithm
    SAGE Publications ; 2019
    In:  Proceedings of the Institution of Mechanical Engineers, Part O: Journal of Risk and Reliability Vol. 233, No. 2 ( 2019-04), p. 235-245
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part O: Journal of Risk and Reliability, SAGE Publications, Vol. 233, No. 2 ( 2019-04), p. 235-245
    Abstract: Traditionally, fault diagnostic strategy is used to obtain the optimal test sequence for binary systems. Actually, a lot of systems are not binary systems, such as multivalued attribute systems. Traditional algorithms generating the test sequence for binary systems and multivalued attribute systems select tests, and then identify and isolate the failure states based on the outcomes of tests. In this study, a novel diagnostic strategy for multivalued attribute system is introduced. This strategy chooses failure states and then finds a suitable test set for the selected failure states. This can avoid the backtracking approach of traditional algorithms. In order to implement this strategy, three main procedures are presented: (1) test sequencing problem is simplified to a combination of the basic test sets with unnecessary tests, and the sets for fault detection and isolation are defined, (2) the optimal test sequence generating algorithm for an individual failure state is proposed, and (3) the priority levels of failure state are determined based on the probability, and a new algorithm, which is used to generate the test sequence for all failure states, is presented. As the implementation process for the new algorithm resembles the growth of branches on a tree, it is defined as growing algorithm. Finally, two cases are used to show how the growing algorithm works, and stochastic simulation experiments are employed to validate universality and stability of the algorithm. The case studies and stochastic simulation experiments demonstrate that the results obtained by the growing algorithm are as accurate as those obtained by the rollout algorithm, and the growing algorithm needs a short running time. Therefore, the growing algorithm is suitable for multivalued attribute system, and it obtains good calculation results with a short running time and high efficiency.
    Type of Medium: Online Resource
    ISSN: 1748-006X , 1748-0078
    URL: Article
    DOI: 10.1177/1748006X18770356
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2246471-2
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