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  • SAGE Publications  (15)
  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 2015
    In:  Transactions of the Institute of Measurement and Control Vol. 37, No. 7 ( 2015-08), p. 892-899
    In: Transactions of the Institute of Measurement and Control, SAGE Publications, Vol. 37, No. 7 ( 2015-08), p. 892-899
    Abstract: This paper is concerned with model predictive control for polytopic systems subject to exogenous disturbance and [Formula: see text]/[Formula: see text] performance constraints. It is shown that a better characterization of [Formula: see text]/[Formula: see text] performance can be provided by introducing additional free parameters. Meanwhile, input constraints are ensured by using a dilated linear matrix inequality technique, so the utilization of actuator capability is improved. These two aspects bring extra degrees of freedom in optimizing control performance. Recursive feasibility and stability of the controller are proved. Numerical examples verify these properties.
    Type of Medium: Online Resource
    ISSN: 0142-3312 , 1477-0369
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2025882-3
    SSG: 3,2
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  • 2
    In: Therapeutic Advances in Neurological Disorders, SAGE Publications, Vol. 9, No. 4 ( 2016-07), p. 310-316
    Abstract: There are limited pharmacological treatments for patients with neurological Wilson’s disease (WD) and a history of copper-chelating treatment failure. Methods: We retrospectively evaluated the clinical records of 38 patients with WD who were treated with sodium dimercaptopropanesulfonate (DMPS) and zinc (group 1) or zinc alone (group 2). All patients had a history of neurological deterioration during their previous treatment with D-penicillamine (DPA). Results: Twenty-one patients were treated with intravenous DMPS for 4 weeks, followed by zinc gluconate for 6 months, and the treatment protocol was repeated twice. Relative to the baseline, repeated DMPS therapy and zinc maintenance therapy decreased neurological scores continuously ( p 〈 0.01). Sixteen patients (76.2%) demonstrated neurological improvements after 1 year of therapy and four patients (19.0%) exhibited neurological deterioration at the follow-up session. In addition, 17 patients were treated with zinc monotherapy for 12 months. Two patients (11.8%) demonstrated neurological improvements and five patients (29.4%) exhibited neurological deterioration. Compared with the patients in group 2, a greater improvement ratio ( p 〈 0.01) and lower deterioration ratio ( p 〈 0.01) were observed in the patients in group 1 after 1 year of therapy. Conclusions: Our findings indicate that the safety and efficacy of combined treatment of DMPS and zinc is superior to those of zinc monotherapy in patients with neurological WD with a history of DPA treatment failure.
    Type of Medium: Online Resource
    ISSN: 1756-2864 , 1756-2864
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2442245-9
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2014
    In:  The International Journal of Lower Extremity Wounds Vol. 13, No. 2 ( 2014-06), p. 88-93
    In: The International Journal of Lower Extremity Wounds, SAGE Publications, Vol. 13, No. 2 ( 2014-06), p. 88-93
    Abstract: Impaired wound-healing activity in diabetes could result from several factors, including severely damaged angiogenic responses, which can affect wound healing process to cause delayed wound repair. Mesenchymal stem cells (MSCs) have been shown to enhance wound healing via multiple effects, including promoting angiogenesis both in vitro and in vivo; however, the mechanisms involved in enhancing diabetic wound healing are barely understood. This article reviews the recent literatures on MSCs treatment for promoting angiogenesis or vascularization in diabetic wounds and the potential mechanisms involved, with an emphasis on the role of paracrine soluble factors. Meanwhile, the potential benefits and related risks associated with the therapeutic use of MSCs have been presented and may lead to better understanding of the influence of MSCs without increasing potential risks. Further investigation will be required to determine the molecular basis of paracrine mechanisms and regulated angiogenesis of MSCs for its rational manipulation for impaired angiogenesis repair and diabetic wound healing.
    Type of Medium: Online Resource
    ISSN: 1534-7346 , 1552-6941
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2135166-1
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2023
    In:  International Journal of Advanced Robotic Systems Vol. 20, No. 2 ( 2023-03-01), p. 172988062311638-
    In: International Journal of Advanced Robotic Systems, SAGE Publications, Vol. 20, No. 2 ( 2023-03-01), p. 172988062311638-
    Abstract: The use of robots to perform tasks in extreme environments instead of humans has gradually become important. For wider applications, robots should be able to adapt to complex environments, such as typical height/width-restricted motion spaces, raised obstacles, and ravines. The structure is the foundation of robot to move and perform tasks. In this study, a variable-attitude robot mechanism is designed and analyzed. With the link leg drive and Mecanum wheel drive, the robot has various configurations and omnidirectional motion capabilities. First, the design and analysis of the wheel drive system are performed, and the mapping relationship between the velocity of the robot and the velocity of the Mecanum wheel is clarified. Second, kinematics of the linkage drive system is analyzed, including the motion space, trajectory characteristics, and the effect of variable axle spacing on the robot motion performance. Subsequently, a simulation is used to verify the rationality of the three motion modes of the robot: walking, wheel drive, and hybrid drive. Finally, a motion simulation of several typical configuration changes in the robot is observed, and the feasibility of the robot mechanism to adapt to a complex environment is verified. This study contributes to the development and application of special advanced robots.
    Type of Medium: Online Resource
    ISSN: 1729-8806 , 1729-8814
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2202393-8
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  • 5
    In: Technology in Cancer Research & Treatment, SAGE Publications, Vol. 18 ( 2019-01-01), p. 153303381987698-
    Abstract: To evaluate the efficacy and safety of hypofractionated stereotactic radiotherapy using CyberKnife for high volume cavernous sinus cavernous hemangiomas. Materials and Methods: We collected data from 12 patients with high volume cavernous sinus cavernous hemangiomas treated with hypofractionated stereotactic radiotherapy using CyberKnife in our institute, including 2 men and 10 women/female child, aged 4 to 60 years. Initial tumor volumes ranged from 11.8 to 96.6 cm 3 with a median of 24.3 cm 3 . Irradiation doses were 19.5 Gy with 3 fractions in 2 patients, 21 Gy with 3 fractions in 8 patients, 25 Gy with 5 fractions in 1 patient, and 30 Gy with 3 fractions in 1 patient. We used 109 to 155 beams during treatment, and target volumes reached over 95% of the prescribed dose. Follow-up ranged from 3 to 54 months. We evaluated the efficacy and safety of the CyberKnife system based on changes in the diagnostic images and involved cranial nerves or symptoms. Results: Of the 12 patients, 11 were followed for 3 to 54 months with a mean follow-up of 16.3 months; 1 patient was lost to in-person follow-up. Lesion volumes in the followed 11 patients were calculated after fractionated radiotherapy. All tumor volumes decreased (28.6%-94.1%) and symptoms improved (including blurred vision, visual field defects, diplopia, headaches, and facial numbness) after therapy. Postoperative magnetic resonance images revealed a tumor volume range of 2.8 to 41.0 cm 3 (median, 6.5 cm 3 ), significantly lower compared with the pretreatment range of 11.8 to 70.1 cm 3 (median, 24.3 cm 3 ; T = 0.00, P = .003 〈 .05). A single patient experienced radiotherapy-related cerebral edema, which resolved after 5 days of mannitol and dexamethasone. Conclusions: Based on the current results, though preliminary, hypofractionated stereotactic radiotherapy using CyberKnife is an effective and safe alternative for high volume cavernous sinus cavernous hemangiomas and is the recommended primary treatment in high-risk patients with this condition.
    Type of Medium: Online Resource
    ISSN: 1533-0346 , 1533-0338
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2146365-7
    detail.hit.zdb_id: 2220436-2
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  • 6
    Online Resource
    Online Resource
    SAGE Publications ; 2014
    In:  Transactions of the Institute of Measurement and Control Vol. 36, No. 5 ( 2014-07), p. 683-695
    In: Transactions of the Institute of Measurement and Control, SAGE Publications, Vol. 36, No. 5 ( 2014-07), p. 683-695
    Abstract: This paper investigates the finite-time H ∞ control problem for discrete-time Markovian jump linear systems with time delay and norm-bounded exogneous disturbance. The stochastic finite-time boundness is achieved by employing an average dwell time approach, which has more design freedom by allowing the stochastic Lyapunov-like function (SLLF) to increase more slowly during the running time of each operation mode. Note that the SLLF increases at every jumping instant rather than at every sampling time instant. Sufficient conditions for the solvability of the controller, which are dependent or independent on the time delay, are given in terms of linear matrix inequalities. Numerical examples are given to verify the efficiency of the proposed method.
    Type of Medium: Online Resource
    ISSN: 0142-3312 , 1477-0369
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2025882-3
    SSG: 3,2
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  • 7
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Proceedings of the Institution of Mechanical Engineers, Part I: Journal of Systems and Control Engineering Vol. 233, No. 8 ( 2019-09), p. 935-944
    In: Proceedings of the Institution of Mechanical Engineers, Part I: Journal of Systems and Control Engineering, SAGE Publications, Vol. 233, No. 8 ( 2019-09), p. 935-944
    Abstract: In this article, the partition of state space is investigated based on the average dwell time theory, and a novel switching condition is proposed. Under the switching condition and strategy, a switched system where all subsystems are unstable is globally exponentially stabilized. Compared with the existing literature, the conclusion is less conservative and more general. Consequently, the conditions appropriate for this exponential stability issue are derived and a computational procedure to solve the bilinear matrix inequality problems and admissible average dwell time is provided. Finally, two numerical examples are used to show the validity and effectiveness of the proposed methods.
    Type of Medium: Online Resource
    ISSN: 0959-6518 , 2041-3041
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2024903-2
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  • 8
    Online Resource
    Online Resource
    SAGE Publications ; 2021
    In:  Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering Vol. 235, No. 16 ( 2021-12), p. 2407-2425
    In: Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering, SAGE Publications, Vol. 235, No. 16 ( 2021-12), p. 2407-2425
    Abstract: This study introduces a new quasi-flapping wing driving mechanism based on a half-rotating mechanism which is capable of pure rotational flapping rather than the more traditional oscillatory flapping method. Lift models for half-rotating wing (HRW) aircraft in hovering flight are proposed based on the kinematics of a HRW prototype and the flow characteristics near the surface of its wing. Alongside further analytical expressions for lift based on kinematic extractions, computational models and a novel lift validation mechanism are used to reinforce the aerodynamic characteristics of the HRW in hovering flight. The aerodynamics of the HRW are experimentally assessed for different wing layouts and wing materials. Results indicate that the flow field generated by the motion of the wing arranged symmetrically on both sides of the body interfere with each other, causing the average lift coefficient of the paired-wing HRW to be less than that of the single-wing HRW. The average lift coefficient of the flexible wing is larger than that of the rigid wing. In addition, the average lift of the flexible wing increases with increasing flexural compliance within a particular range. Lift forces in different flight conditions are calculated using derived formulas alongside representative computational models, through which the derivation of lift variation for the HRW in hovering flight is validated. The theoretical lift curves show reasonable agreement with numerical simulation results in terms of the time course over one stroke cycle. The mechanisms of the HRW for generation and shedding of vortices in hovering flight are further revealed in computed flow field characteristics results. The velocity vectors of the flow field between the HRW and the symmetrically rotating wing indicate that the HRW with asymmetric rotation can generate lift force effectively. The velocity difference between the wing and the fluid is the key factor influencing the structure of generated vortices. In detailed three-dimensional (3D) vortex flows, our computational fluid dynamics study shows that a horseshoe-shaped vortex is first generated in the early downstroke. The horseshoe-shaped vortex subsequently grows into a doughnut-shaped vortex ring, with a jet stream appearing in its core which forms the downwash. The doughnut-shaped vortex ring eventually elongates into a long arc-shaped wake vortex ring. A large increasing lift force is generated during the upstroke, most likely due to the stable distal attached vortices; and in accordance with this, downwash becomes evident in the vortex ring during the downstroke.
    Type of Medium: Online Resource
    ISSN: 0954-4100 , 2041-3025
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2032759-6
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  • 9
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Energy Exploration & Exploitation Vol. 37, No. 4 ( 2019-07), p. 1268-1285
    In: Energy Exploration & Exploitation, SAGE Publications, Vol. 37, No. 4 ( 2019-07), p. 1268-1285
    Type of Medium: Online Resource
    ISSN: 0144-5987 , 2048-4054
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2026571-2
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  • 10
    Online Resource
    Online Resource
    SAGE Publications ; 2022
    In:  Journal of International Medical Research Vol. 50, No. 12 ( 2022-12), p. 030006052211449-
    In: Journal of International Medical Research, SAGE Publications, Vol. 50, No. 12 ( 2022-12), p. 030006052211449-
    Abstract: The case was a 17-year-old young woman with a one-year history of recurrent abdominal pain and discomfort. B-scan ultrasonography identified intussusception and contrast-enhanced computed tomography of the pelvis revealed volvulus. A laparoscopic procedure was planned to identify the reason for the intussusception and obstruction. Intraoperatively, the intussusception was found to be caused by a cauliflower-shaped polypoid tumor measuring approximately 4 × 3 cm. Postoperative pathological examination identified the tumor to be a traditional serrated adenoma of the small intestine, which is rare and has atypical clinical manifestations. If unexplained abdominal pain or gastrointestinal bleeding occurs and an abdominal mass cannot be accurately located, laparoscopic or open surgery should be performed immediately. Early surgery is the most effective and reliable way of securing a prompt diagnosis and a favorable prognosis.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2082422-1
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