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  • 1
    Online Resource
    Online Resource
    Difficulties with prenatal diagnosis of the walker-warburg syndrome
    SAGE Publications ; 2005
    In:  Acta Radiologica Vol. 46, No. 6 ( 2005-10), p. 645-651
    Details
    In: Acta Radiologica, SAGE Publications, Vol. 46, No. 6 ( 2005-10), p. 645-651
    Abstract: We describe a postnatally diagnosed case of Walker-Warburg syndrome – a form of congenital muscular dystrophy with lissencephaly and eye abnormalities. We reviewed the literature to highlight its clinico-radiological diagnostic features and discuss the difficulties encountered with prenatal diagnosis, especially in cases with no positive family history. An increased awareness of this rare but lethal condition, and a high index of suspicion during routine antenatal ultrasound, could prompt further advanced fetal ultrasonography and magnetic resonance imaging, and aid in timely prenatal diagnosis, management, and counseling.
    Type of Medium: Online Resource
    ISSN: 0284-1851 , 1600-0455
    URL: Article
    DOI: 10.1080/02841850510021409
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2005
    detail.hit.zdb_id: 2024579-8
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  • 2
    Online Resource
    Online Resource
    Probable Blastomyces dermatitidis Infection in a Young Rat
    SAGE Publications ; 2013
    In:  Veterinary Pathology Vol. 50, No. 2 ( 2013-03), p. 343-346
    Details
    In: Veterinary Pathology, SAGE Publications, Vol. 50, No. 2 ( 2013-03), p. 343-346
    Abstract: A 21-week-old male untreated control SHR/NCrlNarl rat was found dead during an experiment. Grossly, pulmonary lesions were characterized by multifocal to coalescing firm gray-white nodules randomly scattered on the surface. Microscopically, bronchopneumonia was found with pyogranulomas containing neutrophils, macrophages, and numerous thick-walled yeast cells. Yeast cells, 5 to 25 μm in diameter, with no branching of hyphae were observed by staining with hematoxylin and eosin, Diff-Quik, and periodic acid-Schiff. Furthermore, polymerase chain reaction (PCR) using panfungal and nested PCR primers were used for detection of Blastomyces dermatitidis DNA in the lung tissue. After sequencing and matching with DNA sequences in the GenBank, the sample showed a similarity of 94.6% and 97% to Ajellomyces dermatitidis ( B. dermatitidis), respectively. On the basis of these results, probable pulmonary blastomycosis was diagnosed. The origin of the infection in the colony rat is undetermined.
    Type of Medium: Online Resource
    ISSN: 0300-9858 , 1544-2217
    URL: Article
    DOI: 10.1177/0300985812451624
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2106608-5
    SSG: 22
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  • 3
    Online Resource
    Online Resource
    Prevalence of Anxiety Disorders in Hong Kong Chinese Children With ADHD
    SAGE Publications ; 2018
    In:  Journal of Attention Disorders Vol. 22, No. 5 ( 2018-03), p. 403-413
    Details
    In: Journal of Attention Disorders, SAGE Publications, Vol. 22, No. 5 ( 2018-03), p. 403-413
    Abstract: Objective: This study examined the prevalence and correlates of anxiety disorders in Chinese children with ADHD. Method: Overall, 120 children with ADHD aged 6 to 12 years were recruited, and the parent version of computerized Diagnostic Interview Schedule for Children–Version 4 was administrated to their primary caretakers. Results: The prevalence rate of anxiety disorders was 27.5%, which is consistent with the reports of previous Asian and Western studies. Among the children with ADHD and anxiety disorders, more than 50% of them also had comorbid oppositional defiant disorder or conduct disorder (ODD/CD), which yielded an adjusted odds ratio of 3.0 in multivariable analysis for anxiety disorder, with comorbid ODD/CD. In addition, anxiety disorders were positively associated with inattention symptoms in children with both disorders. Conclusion: Clinicians should perform screening and careful assessment for anxiety symptoms in children with ADHD, particularly those suffering from comorbid ODD/CD.
    Type of Medium: Online Resource
    ISSN: 1087-0547 , 1557-1246
    URL: Article
    DOI: 10.1177/1087054714562830
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2188086-4
    SSG: 5,2
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  • 4
    Online Resource
    Online Resource
    Pet dogs owned by lupus patients are at a higher risk of developing lupus
    SAGE Publications ; 2004
    In:  Lupus Vol. 13, No. 6 ( 2004-06), p. 442-449
    Details
    In: Lupus, SAGE Publications, Vol. 13, No. 6 ( 2004-06), p. 442-449
    Abstract: The aim of this study is to determine whether pet dogs owned by patients with systemic lupus erythematosus (SLE) are at a higher risk of developing SLE. Diagnosis of canine SLE was mainly based on the 11 diagnostic criteria for human SLE and two marked immunological features of canine SLE. Among 59 pet dogs owned by 37 SLE patients, 11 (18.64%) were ANA positive, and three (5.08%) had SLE. In contrast, of 187 pet dogs owned by non-SLE households, nine (4.81%) were ANA positive, and none (0%) had SLE. Among 650 outpatient dogs registered in the veterinary hospital, 34 (5.23%) were ANA positive, and six (0.92%) had SLE. Frequency of ANA and SLE among pet dogs owned by SLE patients was significantly higher than in pet dogs owned by non-SLE households (P 1 /4 0.001 for ANA; P 1 /4 0.013 for SLE) and in outpatient dogs (P, 0.001 for ANA; P 1 /4 0.032 for SLE). With respect to canine SLE development, the relative risk or risk ratio (R)of human SLE contact varied from 5.5 (compared with outpatient dogs) to near the infinite (compared with dogs owned by non-SLE households). The prevalence of canine SLE among pet dogs of SLE patients was therefore estimated to be 508 per 10 000 [95% confidence interval (95% CI), 0-1068]. In conclusion, pet dogs with human SLE contact were at a higher risk of developing SLE. Our results indicate that a common environmental factor or zoonotic agent may be involved in the development of human and canine SLE.
    Type of Medium: Online Resource
    ISSN: 0961-2033 , 1477-0962
    URL: Article
    DOI: 10.1191/0961203303lu1039oa
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2004
    detail.hit.zdb_id: 2008035-9
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  • 5
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    Online Resource
    Transplant outcomes in kidney recipients with lupus nephritis, and systematic review
    SAGE Publications ; 2020
    In:  Lupus Vol. 29, No. 3 ( 2020-03), p. 248-255
    Details
    In: Lupus, SAGE Publications, Vol. 29, No. 3 ( 2020-03), p. 248-255
    Abstract: Despite improved survival of patients with lupus nephritis (LN), some require kidney transplantation because of progression to end-stage renal disease (ESRD). However, the transplant outcomes of these patients and other recipients have not been thoroughly compared. Methods In total, 1848 Korean kidney recipients who underwent transplantation from 1998 to 2017 at two tertiary referral centers were evaluated retrospectively. Among them, 28 recipients with LN, and 50 control recipients matched by age, sex, and donor type, were compared with respect to graft and patient survival. We pooled our data with 17 previous cohort studies in which the graft survival of recipients with LN was described in detail. Results During the median follow-up period of 9.5 years (maximum 21 years), graft failure (GF) occurred in 10.7% and 16.0% of LN and control recipients, respectively. No differences were found in the rates of GF and death-censored graft failure or patient survival between the two groups. The risks of acute T cell-mediated and antibody-mediated rejection were also similar between the two groups. The pooled analysis showed similar 1- and 5-year graft survival rates between LN and control recipients. Conclusions Kidney transplantation is an acceptable option in patients with concurrent LN and ESRD.
    Type of Medium: Online Resource
    ISSN: 0961-2033 , 1477-0962
    URL: Article
    DOI: 10.1177/0961203320902524
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2008035-9
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  • 6
    Online Resource
    Online Resource
    Effect of Propofol Infusion on the Endocrine Response to Cardiac Surgery
    SAGE Publications ; 1995
    In:  Anaesthesia and Intensive Care Vol. 23, No. 5 ( 1995-10), p. 543-547
    Details
    In: Anaesthesia and Intensive Care, SAGE Publications, Vol. 23, No. 5 ( 1995-10), p. 543-547
    Abstract: The effect of propofol infusion on the stress response was studied in patients undergoing coronary artery bypass graft (CABG). Ten patients received propofol infusion during cardiopulmonary bypass (CPB) and ten controls received diazepam. Blood levels of Cortisol, adrenaline and noradrenaline were sampled. There was a significant reduction in all three hormones (P 〈 0.05) in the study group. In addition, the amount of sodium nitroprusside used during CPB was significantly reduced (P 〈 0.05).
    Type of Medium: Online Resource
    ISSN: 0310-057X , 1448-0271
    URL: Article
    DOI: 10.1177/0310057X9502300502
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1995
    detail.hit.zdb_id: 2053705-0
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  • 7
    Online Resource
    Online Resource
    Effect of Calcium Channel Blockers on Serotonin Uptake
    SAGE Publications ; 1990
    In:  Experimental Biology and Medicine Vol. 193, No. 4 ( 1990-04-01), p. 326-330
    Details
    In: Experimental Biology and Medicine, SAGE Publications, Vol. 193, No. 4 ( 1990-04-01), p. 326-330
    Type of Medium: Online Resource
    ISSN: 1535-3702 , 1535-3699
    URL: Article
    DOI: 10.3181/00379727-193-43043
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1990
    detail.hit.zdb_id: 2020856-X
    SSG: 12
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  • 8
    Online Resource
    Online Resource
    Airway changes in children with mucopolysaccharidoses: CT evaluation
    SAGE Publications ; 2002
    In:  Acta Radiologica Vol. 43, No. 1 ( 2002-01), p. 40-43
    Details
    In: Acta Radiologica, SAGE Publications, Vol. 43, No. 1 ( 2002-01), p. 40-43
    Abstract: Objective: To assess the CT findings of the airway in children with mucopolysaccharidoses (MPS). Material and Methods: The study included 13 patients (9 boys, 4 girls; age range 2-17 years; mean age 9.2 years) with MPS: 6 with Hunter syndrome, 3 with Maroteaux-Lamy syndrome, 2 with Sanfilippo syndrome, 1 with Hurler/Scheie syndrome and 1 with Morquio syndrome. CT of the airways was done in the axial section with 3-mm collimation from the oropharynx at the level of C3 to the base of the lung. The shape of the vocal cords and trachea at the level of T1 was evaluated. The tracheal surface area (TSA) at the level of T1 was measured both in patients and in age-matched subjects. Results: CT showed an abnormality of the vocal cords in 7 of the 13 patients. Six patients had an abnormal shape and 7 had an inhomogenous density. The abnormalities included elliptical (5 of 6) and star-shaped (1 of 6) cords. Eight of 13 tracheas were also abnormal, either U-shaped (6 of 8) or worm-shaped (2 of 8). The TSA was significantly smaller in patients (79.6±28.9 mm 2 ) than in control subjects (138.1±50.1 mm 2 ). The TSA of those ≤⃒9 years was 61.4±15.2 mm 2 as compared with 99.9±23.5 mm 2 for the control group. The TSA of patients ≥11 years was 107.1±25.3 mm 2 as compared with 187.6±32.0 mm 2 for the control group. Conclusion: Significant changes in the shape of the vocal cords and trachea in patients with MPS were found. The most common abnormal configuration of trachea was the U-shape. The TSA was smaller in patients with MPS than in controls. The airway changes may be due to abnormal submucosal storage of substances such as keratan or dermatan sulfate.
    Type of Medium: Online Resource
    ISSN: 0284-1851 , 1600-0455
    URL: Article
    DOI: 10.1080/028418502127347628
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2002
    detail.hit.zdb_id: 2024579-8
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  • 9
    Online Resource
    Online Resource
    Cortical Reorganization for Response Regulation With Unilateral Thalamic Stroke Detected by Functional MRI
    SAGE Publications ; 2007
    In:  Neurorehabilitation and Neural Repair Vol. 21, No. 5 ( 2007-09), p. 467-471
    Details
    In: Neurorehabilitation and Neural Repair, SAGE Publications, Vol. 21, No. 5 ( 2007-09), p. 467-471
    Abstract: To understand neural reorganization of response regulation after stroke, a 54-year-old woman with a chronic left thalamic stroke performed a task requiring decisions about the directionality of an arrow during cerebral functional magnetic resonance imaging. Her performance was compared to 13 matched healthy control subjects. Her behavioral responses were slower but as accurate. Bilateral frontal activations were observed in the right medial frontal gyrus (BA 9), left superior frontal gyrus (BA 45), and left frontal rectus gyrus (BA 11). Activation in the right medial frontal gyrus, along with activity in close proximity to the anterior cingulate cortex, was observed, which may reflect reorganization of activity after the loss of function of the anterior cingulate cortex.
    Type of Medium: Online Resource
    ISSN: 1545-9683 , 1552-6844
    URL: Article
    DOI: 10.1177/1545968306298415
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2007
    detail.hit.zdb_id: 2100545-X
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  • 10
    Online Resource
    Online Resource
    Epidural Infusion of Bupivacaine 0.0625% plus Fentanyl 3.3 μg/ml Provides Better Postoperative Analgesia than Patient-Controlled Analgesia with Intravenous Morphine after Gynaecological Laparotomy
    SAGE Publications ; 1997
    In:  Anaesthesia and Intensive Care Vol. 25, No. 5 ( 1997-10), p. 476-481
    Details
    In: Anaesthesia and Intensive Care, SAGE Publications, Vol. 25, No. 5 ( 1997-10), p. 476-481
    Abstract: One hundred and twenty women undergoing gynaecological abdominal operations were randomized to receive either epidural bupivacaine 0.0625%+fentanyl 3.3μg/ml infusion (Group EPI, n=57), or patient-controlled intravenous morphine analgesia (Group PCA, n=54) for postoperative pain relief. The groups were comparable in demographic data, types and duration of operation. Group EPI achieved significantly lower verbal rating scale of pain (VRS) at rest at 0, 4, 12, 16, 20, 28 and 40th postoperative hours. The VRS during cough were also significantly lower in Group EPI at 0, 4, 8, 12, 28 and 36th postoperative hours. None of the patients had respiratory depression or hypotension. Nausea/vomiting occurred in 52.6%/33.3% of patients in Group EPI and 52.7%/37.0% in Group PCA. Most patients (84.2% in Group EPI and 72.2% in Group PCA) rated their pain management as “good”. We conclude that epidural infusion of bupivacaine 0.0625% and fentanyl 3.3μg/ml provide better analgesia than patient-controlled intravenous morphine after gynaecological laparotomy
    Type of Medium: Online Resource
    ISSN: 0310-057X , 1448-0271
    URL: Article
    DOI: 10.1177/0310057X9702500504
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1997
    detail.hit.zdb_id: 2053705-0
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