GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Optimization of the Essential Oil Extraction Process from Dong Van Marjoram ( E. winitiana var. dongvanensis Phuong.) by Using Microwave Assisted Hydrodistillation, and the Bioactivities of the Oil Against Some Cancer Cell Lines and Bacteria
    SAGE Publications ; 2021
    In:  Natural Product Communications Vol. 16, No. 10 ( 2021-10), p. 1934578X2110542-
    Details
    In: Natural Product Communications, SAGE Publications, Vol. 16, No. 10 ( 2021-10), p. 1934578X2110542-
    Abstract: This study reports on the optimization of a microwave-assisted distillation process to obtain Dong Van marjoram essential oil, and the determination of its composition, content of constituents, and cytotoxic and antimicrobial activities. Using the response surface method (RSM), the optimal essential oil distillation conditions were determined as material size 0.74 (cm), water to material ratio 4.14:1 (mL/g), microwave power 302.4 (W), and distillation time 2.1 hours. At optimal conditions, the mass of Dong Van marjoram essential oil obtained was 0.887 ± 0.007 g, corresponding to a content of 0.6% essential oil in the material. GC-MS and GC-FID methods showed that the main chemical constituents of Dong Van marjoram essential oils obtained were rosefuran epoxide (44.9%), caryophyllene (10.8%), germacrene D (2.6%), and α-humulene (1.3%). The essential oil exhibited moderate inhibition against both tested cancer cell lines, with IC 50 values of 23.9 µg/mL (for PC3) and 56.2 µg/mL (for A549). However, the oil exhibited strong effectiveness against three bacterial strains, Escherichia coli, Bacillus subtilis, and Staphylococcus aureus, and a yeast strain, Saccharomyces cerevisiae, with minimal inhibitory concentration (MIC) values ranged from 50 to 100 µg/mL.
    Type of Medium: Online Resource
    ISSN: 1934-578X , 1555-9475
    URL: Article
    DOI: 10.1177/1934578X211054235
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2430442-6
    SSG: 15,3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Development of a new magnetorheological fluid–based brake with multiple coils placed on the side housings
    SAGE Publications ; 2019
    In:  Journal of Intelligent Material Systems and Structures Vol. 30, No. 5 ( 2019-03), p. 734-748
    Details
    In: Journal of Intelligent Material Systems and Structures, SAGE Publications, Vol. 30, No. 5 ( 2019-03), p. 734-748
    Abstract: In this research, a new configuration of magnetorheological fluid–based brake with multiple coils placed on each side of the brake housing (multiple side-coil magnetorheological fluid–based brake) is proposed, optimally designed, and evaluated. With this configuration, the multiple side-coil magnetorheological fluid–based brake is expected to provide higher braking torque and more compact size than the traditional magnetorheological fluid–based brake. After a brief introduction about the development of magnetorheological fluid–based brake, the configuration of multiple side-coil magnetorheological fluid–based brake is proposed. Braking torque of the proposed magnetorheological fluid–based brake is then analyzed based on the Bingham plastic rheological model of magnetorheological fluid. The optimization of the proposed multiple side-coil magnetorheological fluid–based brake, the magnetorheological fluid–based brake with one coil placed on each side of the brake housing (single side-coil magnetorheological fluid–based brake), and the conventional magnetorheological fluid–based brake is then performed considering maximum braking torque and mass of the brakes. Based on the optimal results, advanced performance characteristics of the proposed magnetorheological fluid–based brake are figured out. In addition, experimental works are conducted to validate the performance of the proposed multiple side-coil magnetorheological fluid–based brake.
    Type of Medium: Online Resource
    ISSN: 1045-389X , 1530-8138
    URL: Article
    DOI: 10.1177/1045389X18818385
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2088313-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Bridging Therapy and Direct Thrombectomy for Acute Ischemic Stroke: A Prospective Cohort Study
    SAGE Publications ; 2020
    In:  Journal of Stroke Medicine Vol. 3, No. 2 ( 2020-12), p. 124-130
    Details
    In: Journal of Stroke Medicine, SAGE Publications, Vol. 3, No. 2 ( 2020-12), p. 124-130
    Abstract: It remains controversial if intravenous thrombolysis (IVT) prior to mechanical thrombectomy (MTE) is superior to MTE alone in patients with acute ischemic stroke caused by large vessel occlusion. We aim to compare functional outcomes, mortality, reperfusion, and intracranial hemorrhage rates in bridging therapy (IVT prior thrombectomy) and MTE alone groups within 6 h from symptom onset. Materials and Methods: Consecutive hospitalized patients (September 2017 and July 2018) with acute large artery occlusion within the anterior cerebral circulation eligible for MTE with or without prior IVT were included. A modified Rankin Scale score of 0 to 2 was considered as good functional outcome at 90 days. Successful reperfusion was defined as a Thrombolysis in Cerebral Infarction scale of 2b to 3. Results: Of the 124 patients included, 56 (45.2%) received bridging therapy and 68 (54.8%) received MTE alone. Patients receiving bridging therapy were younger (median, 56 vs 63, P = .045) and had shorter onset-to-groin time (median, 270 vs 370 min, P 〈 .001) than those receiving MTE alone. Successful reperfusion rate was significantly greater in the bridging therapy group (87.5% vs 72.1%, P = 0.03). There were no statistically significant differences between the 2 groups in functional independence (bridging 58.9% vs 75.0%, P = 0.07), mortality at 90 days (bridging 14.3% vs 7.4%, P = 0.22), parenchymal hematoma type 2 (bridging 3.6% vs 2.9%, P 〉 .99), and any hemorrhage (bridging 42.3% vs 26.5%, P = 0.07). Conclusion: Compared to MTE alone, bridging therapy with IVT improved the reperfusion rate but not other outcomes. Further clinical trials are needed to confirm our findings.
    Type of Medium: Online Resource
    ISSN: 2516-6085 , 2516-6093
    URL: Article
    DOI: 10.1177/2516608520976275
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 3011515-2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    The Impact of the Third Mission on Teaching and Research Performance: Evidence From Academic Scholars in an Emerging Country
    SAGE Publications ; 2021
    In:  SAGE Open Vol. 11, No. 4 ( 2021-10), p. 215824402110544-
    Details
    In: SAGE Open, SAGE Publications, Vol. 11, No. 4 ( 2021-10), p. 215824402110544-
    Abstract: Despite the plethora of empirical evidence on the associations between the third mission of academic scholars (i.e., academic engagement, academic commercialization, and public engagement) and their performance regarding two other missions (teaching and research), we have not known much about such relationships in the context of emerging countries such as Vietnam. To examine this problem, we delivered a survey with 245 Vietnamese academic scholars. Findings extracted from exploratory factor analysis revealed that the third mission of Vietnamese academic scholars might be divided into two distinct factors: (i) academic engagement and commercialization and (ii) public engagement and extra work. Subsequently, results of multiple regression revealed that while both academic engagement and commercialization, public engagement and extra work, as well as the interaction of these two factors, have positive impacts on research performance, only the second factor has a positive impact on teaching performance. This study extended the current mixed understandings on the associations among the three missions of academic scholars with evidence from an emerging country such as Vietnam. This study also provides implications for stakeholders, including policymakers, university leaders, and industry practitioners.
    Type of Medium: Online Resource
    ISSN: 2158-2440 , 2158-2440
    URL: Article
    DOI: 10.1177/21582440211054493
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2628279-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Endovascular treatment for acute ischemic stroke beyond the 24-hour time window: selection by target mismatch profile
    SAGE Publications ; 2023
    In:  International Journal of Stroke
    Details
    In: International Journal of Stroke, SAGE Publications
    Abstract: Introduction: Endovascular treatment for acute ischemic stroke patients with large vessel occlusion has been established as a promising clinical intervention within a late time window of 6-24-hours after symptom onset. Patients with slow progression, however, may still benefit from endovascular treatment beyond the 24-hour time window (very late window). Aim: To report insight into the potential clinical benefits of endovascular treatment for acute ischemic stroke beyond 24 hours from symptom onset. Methods: A retrospective analysis was performed on consecutive patients undergoing endovascular treatment for acute anterior circulation large vessel occlusion ischemic stroke beyond 24 hours. Participants were recruited between July 2019 and November 2020. Patients were selected based on the DAWN/DEFUSE 3 criteria (Perfusion-RAPID, IschemaView), and patients receiving treatment beyond 24 hours were compared to a group of patients receiving endovascular treatment between 6-24 hours after symptom onset. The primary outcome was the proportion of patients with functional independence at 90 days (modified Rankin Scale score of 0-2). The secondary outcomes were shift mRS analysis and successful reperfusion was defined by TICI 2b-3 on the final procedure. Safety outcomes were symptomatic intracranial hemorrhage and death at the 90-day follow-up. Propensity score-matched analyses were employed to rectify the imbalanced baseline characteristics between the two groups. Results: 166 patients were recruited with a median age of 63.0 [56.0-69.0] and 28.9% of all patients were females. Patients in the beyond 24-hour group had a longer onset-to-groin time (median, 27.2 vs. 14.3 hours, p 〈 0.001) than those in the 6 to 24-hour group. There were no statistically significant differences between the two groups in NIHSS (median, 12.0 vs. 15.0, p=0.37), perfusion imaging characteristics (core: median, 11.0 vs. 9.0 ml, p=0.86; mismatch volume: median, 106.0 vs. 96.0, p=0.44; mismatch ratio: 6.46 vs. 7.24, p=0.91), and perfusion-to-groin time (median, 72.5 vs. 76.0 min, p=0.77). No significant differences were noted among patients between the two groups in the primary endpoint functional independence analysis (50.0% vs. 46.6%, p=0.77) and in the safety endpoint analysis: mortality (15.0% vs. 11.0%, p=0.71) or symptomatic hemorrhage (0% vs. 3.42%, p 〉 0.999). In propensity score–matched analyses, there were no significant differences among patients between the two groups in functional independence (50.0% vs. 54.8%, p=0.74), mortality (16.7% vs. 9.68%, p=0.50) or symptomatic hemorrhage (0% vs. 6.45%, p=0.53). Conclusions: Endovascular treatment can be performed safely and effectively in large vessel occlusion patients beyond 24 hours from symptom onset when selected by target mismatch profile. The clinical outcome of these patients was comparable to those treated in the 6-24 hour window. Larger studies are needed to confirm these findings.
    Type of Medium: Online Resource
    ISSN: 1747-4930 , 1747-4949
    URL: Article
    DOI: 10.1177/17474930231208817
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2211666-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Global impact of COVID-19 on stroke care
    SAGE Publications ; 2021
    In:  International Journal of Stroke Vol. 16, No. 5 ( 2021-07), p. 573-584
    Details
    In: International Journal of Stroke, SAGE Publications, Vol. 16, No. 5 ( 2021-07), p. 573-584
    Abstract: The COVID-19 pandemic led to profound changes in the organization of health care systems worldwide. Aims We sought to measure the global impact of the COVID-19 pandemic on the volumes for mechanical thrombectomy, stroke, and intracranial hemorrhage hospitalizations over a three-month period at the height of the pandemic (1 March–31 May 2020) compared with two control three-month periods (immediately preceding and one year prior). Methods Retrospective, observational, international study, across 6 continents, 40 countries, and 187 comprehensive stroke centers. The diagnoses were identified by their ICD-10 codes and/or classifications in stroke databases at participating centers. Results The hospitalization volumes for any stroke, intracranial hemorrhage, and mechanical thrombectomy were 26,699, 4002, and 5191 in the three months immediately before versus 21,576, 3540, and 4533 during the first three pandemic months, representing declines of 19.2% (95%CI, −19.7 to −18.7), 11.5% (95%CI, −12.6 to −10.6), and 12.7% (95%CI, −13.6 to −11.8), respectively. The decreases were noted across centers with high, mid, and low COVID-19 hospitalization burden, and also across high, mid, and low volume stroke/mechanical thrombectomy centers. High-volume COVID-19 centers (−20.5%) had greater declines in mechanical thrombectomy volumes than mid- (−10.1%) and low-volume (−8.7%) centers (p  〈  0.0001). There was a 1.5% stroke rate across 54,366 COVID-19 hospitalizations. SARS-CoV-2 infection was noted in 3.9% (784/20,250) of all stroke admissions. Conclusion The COVID-19 pandemic was associated with a global decline in the volume of overall stroke hospitalizations, mechanical thrombectomy procedures, and intracranial hemorrhage admission volumes. Despite geographic variations, these volume reductions were observed regardless of COVID-19 hospitalization burden and pre-pandemic stroke/mechanical thrombectomy volumes.
    Type of Medium: Online Resource
    ISSN: 1747-4930 , 1747-4949
    URL: Article
    DOI: 10.1177/1747493021991652
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2211666-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...