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  • 1
    Online Resource
    Online Resource
    The incremental value of myocardial viability, evaluated by 18F-fluorodeoxyglucose positron emission tomography, and cardiovascular magnetic resonance for mortality prediction in patients with previous myocardial infarction and symptomatic heart failure
    SAGE Publications ; 2023
    In:  Perfusion Vol. 38, No. 6 ( 2023-09), p. 1288-1297
    Details
    In: Perfusion, SAGE Publications, Vol. 38, No. 6 ( 2023-09), p. 1288-1297
    Abstract: To find the imaging mortality predictors in patients with previous myocardial infarction (MI), symptomatic heart failure (HF), and reduced left ventricle (LV) ejection fraction (EF). Methods for the study 39 patients were selected prospectively with prior MI, symptomatic HF, and LVEF ≤40%. All patients underwent transthoracic echocardiography (TTE), single-photon emission computed tomography myocardial perfusion imaging (SPECT MPI), 18F-FDG positron emission tomography (FDG PET). 31 patients underwent cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE). Patients were divided into two groups: 1 group – cardiac death; 2 group – no cardiac death. Myocardial scars were assessed on a 5-point-scale. Follow-up data was obtained. Results Imaging features disclosed significant difference ( p 〈 0.05) of defect score (CMR and SPECT-PET), LV end-diastolic diameter (EDD) (TTE), LVEDD index (CMR), LV global longitudinal strain (CMR) and LV global circumferential strain (CMR) between the groups. Predictors of cardiac death were: LVEDD index (TTE) and LV global longitudinal strain. The cut-off values to predict cardiac death were: defect score (CMR) 25 (AUC, 79.5%; OR 1.8, 95% CI 1.2–2.7), SPECT-PET defect score 22 (AUC, 73.9%; OR 0.5, 95% CI 0.3–0.7), LVEDD (TTE) 58 mm (AUC, 88.4%; OR 23.6, 95% CI 2.6–217.7), LVEDDi 30 mm/m 2 (TTE) (AUC, 73.6%; OR 22.0, 95% CI 1.9–251.5), LVEDDi 33.6 mm/m 2 (CMR) (AUC, 73.6%; OR 22.0, 95% CI 1.9–251.5), LV global longitudinal strain −13.4 (AUC, 87.8%; OR 2.1, 95% CI 1.2–3.7) and LV global circumferential strain −16.3 (AUC, 76.1%; OR 1.9, 95% CI 1.2–3.0). Conclusions Imaging features, such as defect score (CMR) 〉 25, SPECT-PET defect score 〉 22, LVEDD (TTE) 〉 58 mm, LVEDDi (TTE) 〉 30 mm/m 2 , LVEDDi (CMR) 〉 33.6 mm/m 2 , LV global longitudinal strain −13.4 and LV global circumferential strain −16.3, may increase sensitivity and specificity of FDG PET and LGE CMR predicting of late mortality.
    Type of Medium: Online Resource
    ISSN: 0267-6591 , 1477-111X
    URL: Article
    DOI: 10.1177/02676591221100739
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2029611-3
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  • 2
    Online Resource
    Online Resource
    Echocardiographic findings on aortic stenosis: an observational, prospective, and multi-center registry
    SAGE Publications ; 2021
    In:  Perfusion Vol. 36, No. 3 ( 2021-04), p. 269-276
    Details
    In: Perfusion, SAGE Publications, Vol. 36, No. 3 ( 2021-04), p. 269-276
    Abstract: The aim of this aortic stenosis registry was to investigate the changes of routine echocardiographic indices and strain in patients with moderate-to-severe aortic stenosis over a 6-month follow-up period. Methods: Our aortic stenosis registry is observational, prospective, multicenter registry of nine countries, with 197 patients with aortic valve area less than 1.5 cm 2 . The enrolment took place from January to August 2017. We excluded patients with uncontrolled atrial arrhythmias, pulmonary hypertension or cardiomyopathies, as well as those with hemodynamically significant valvular disease other than aortic stenosis. We included patients who did not require intervention and who had a complete follow-up study. Results: In patients with preserved ejection fraction, left ventricular mass has significantly increased between baseline and follow-up studies (218 ± 34 grams vs 253 ± 29 grams, p = 0.02). However, when indexed to body surface area, there was no significant difference. Left ventricular global longitudinal strain significantly decreased (-19.7 ± -4.8 vs (-16.4 vs -3.8, p = 0.01). Left atrial volume was significantly higher at follow-up (p = 0.035). Right ventricular basal diameter and mid-cavity diameter were greater at the follow-up (p = 0.04 and p = 0.035, respectively). Patients with low-flow low-gradient aortic stenosis had significantly lower global longitudinal strain (-12.3% ± -3.9% vs -19.7% ± -4.8%, p = 0.01). Conclusion: Left atrial dilatation is one of the first changes to take place in low-flow low-gradient aortic stenosis patients even when left ventricular dimensions and function remains intact. Global longitudinal strain is an important determinant of left ventricular systolic and diastolic dysfunction and right ventricular function is an important parameter of aortic stenosis assessment. Accordingly, our registry has further shed the light on these indices role as multisite follow-up of aortic stenosis.
    Type of Medium: Online Resource
    ISSN: 0267-6591 , 1477-111X
    URL: Article
    DOI: 10.1177/0267659120924921
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2029611-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
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