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  • 1
    Online Resource
    Online Resource
    Image Challenge: An Engaging New Feature in Veterinary Pathology
    SAGE Publications ; 2018
    In:  Veterinary Pathology Vol. 55, No. 4 ( 2018-07), p. 485-485
    Details
    In: Veterinary Pathology, SAGE Publications, Vol. 55, No. 4 ( 2018-07), p. 485-485
    Type of Medium: Online Resource
    ISSN: 0300-9858 , 1544-2217
    URL: Article
    DOI: 10.1177/0300985818771148
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2106608-5
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  • 2
    Online Resource
    Online Resource
    2020 ACVP, ASVCP, and ISACP Concurrent Annual Meeting: From Novel Insights Into COVID-19 to Unconventional Animal Models
    SAGE Publications ; 2020
    In:  Veterinary Pathology Vol. 57, No. 5 ( 2020-09), p. 598-598
    Details
    In: Veterinary Pathology, SAGE Publications, Vol. 57, No. 5 ( 2020-09), p. 598-598
    Type of Medium: Online Resource
    ISSN: 0300-9858 , 1544-2217
    URL: Article
    DOI: 10.1177/0300985820932141
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
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  • 3
    Online Resource
    Online Resource
    Feline mesothelioma: case report and review of cytologic, immunocytochemical, histopathologic, and immunohistochemical findings
    SAGE Publications ; 2021
    In:  Journal of Veterinary Diagnostic Investigation Vol. 33, No. 4 ( 2021-07), p. 753-757
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 33, No. 4 ( 2021-07), p. 753-757
    Abstract: Mesotheliomas are uncommon neoplasms that arise from mesothelial cells in either the abdominal or thoracic cavities and are rarely diagnosed in cats. A 10-y-old spayed female domestic shorthair cat was presented to the Louisiana State University oncology service for evaluation of a large amount of abdominal effusion. Abdominal ultrasound identified a large mesenteric mass with numerous ill-defined nodules. An abdominocentesis was performed with cytologic and immunocytochemical findings consistent with a neoplastic effusion, with large clusters of epithelioid cells that exhibited strong cytoplasmic expression of pancytokeratin, vimentin, and Wilms tumor 1 antigens. Further testing was declined, and meloxicam was prescribed until the cat died 23 d after initial presentation. Upon postmortem examination, the omentum was contracted into a firm mass adhered to multiple organs and accompanied by numerous small white nodules throughout the abdominal cavity. On histopathology and immunohistochemistry, neoplastic cells were found throughout the abdominal cavity; 60–95% exhibited moderate-to-strong cytoplasmic immunoreactivity for cytokeratin, vimentin, and Wilms tumor 1 protein. The final diagnosis was an epithelioid mesothelioma. Our case illustrates the utility of cytology, immunocytochemistry, and its relation to histology and immunohistochemistry. We also reviewed the reported cases of feline mesothelioma.
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/10406387211017489
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2265211-5
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  • 4
    Online Resource
    Online Resource
    Molecular Detection of Leptospira Kirschneri in Tissues of a Prematurely Born Foal
    SAGE Publications ; 2005
    In:  Journal of Veterinary Diagnostic Investigation Vol. 17, No. 1 ( 2005-01), p. 67-71
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 17, No. 1 ( 2005-01), p. 67-71
    Abstract: Leptospirosis was identified to be the possible cause of premature birth in a foal on a farm with a history of repeated abortions. Using an appropriate polymerase chain reaction (PCR) assay, the presence of Leptospira kirschneri was detected in the tissues of the prematurely born foal. Further confirmation of L. kirschneri was obtained by nucleotide sequence analysis of the PCR-amplified DNA fragment and the partial 16S ribosomal RNA gene sequence. This report further supports mounting evidence that a PCR assay capable of detecting L. kirschneri should be included in routine diagnostic investigations in which Leptospira spp. infection is suspected.
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/104063870501700114
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2005
    detail.hit.zdb_id: 2265211-5
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  • 5
    Online Resource
    Online Resource
    Polypoid Uterine Leiomyosarcomas in a Sheep
    SAGE Publications ; 2007
    In:  Journal of Veterinary Diagnostic Investigation Vol. 19, No. 3 ( 2007-05), p. 309-312
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 19, No. 3 ( 2007-05), p. 309-312
    Abstract: Leiomyosarcoma was diagnosed in the uterus surgically removed from a 3-year-old pet Suffolk ewe with a history of bleeding from the vulva, spontaneous lactation, and nursing behavior. The uterus contained multiple well-circumscribed, soft, intraluminal polypoid masses of variable sizes (0.5–4 cm). The masses were red, with white, smooth, and glistening cut surfaces. Histologically they comprised variably dense sheets of moderately pleomorphic, plump spindle cells embedded in richly vascularized stroma. The mitotic index was usually low (0-1/high-power field), but in some polyps there were up to 10 mitoses/high-power field. Neoplastic cells stained positive for alpha smooth muscle actin (α-SMA) by immunohistochemistry. Ultrastructural features of neoplastic cells included the presence of basal lamina, scant microfilaments, contracted nuclei with blunt ends, and flat intercellular junctions. Uterine leiomyosarcoma was diagnosed based on cellular morphology and atypia and positive immunohistochemistry for α-SMA.
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/104063870701900316
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2007
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  • 6
    Online Resource
    Online Resource
    Muscular Pseudohypertrophy (Steatosis) in a Bovine Fetus
    SAGE Publications ; 2007
    In:  Journal of Veterinary Diagnostic Investigation Vol. 19, No. 2 ( 2007-03), p. 198-201
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 19, No. 2 ( 2007-03), p. 198-201
    Abstract: Muscular pseudohypertrophy was diagnosed in the cervical musculature of a full-term crossbred Simmental fetus delivered by fetotomy. Only head and cervical regions were submitted for pathologic examination; the rest of the fetal body was reportedly normal. The neck musculature of the fetus was markedly deformed by 23 cm and 18 cm in diameter, firm, spherical masses that consisted of enlarged and pale left splenius and right serratus ventralis cervicis muscle, respectively, covered by intact skin. Additionally, lipomatous masses were present within the cervical vertebral canal, compressing the spinal cord. Microscopically, the prominent muscular enlargement was due to massive adipose and fibrous connective tissue replacement of atrophic muscle. Focal myelodysplasia and astrocytosis affecting the grey matter was detected in the mid-cervical region of the spinal cord, accompanied by degeneration in the ascending and descending tracts of the remaining cord segments. Abnormal spinal cord development as a result of severe spinal cord compression by the lipomatous masses within the spinal canal leading to replacement of muscle by fat and fibrous tissue was considered to be the cause of the muscular malformation in this fetus.
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/104063870701900212
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2007
    detail.hit.zdb_id: 2265211-5
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  • 7
    Online Resource
    Online Resource
    From Newly Described Diseases in Artic Foxes to the Connection Between Cancer and the Gut Microbiome: Award-Winning Presentations Await You at the 2019 ACVP and ASVCP Concurrent Annual Meeting
    SAGE Publications ; 2019
    In:  Veterinary Pathology Vol. 56, No. 5 ( 2019-09), p. 654-655
    Details
    In: Veterinary Pathology, SAGE Publications, Vol. 56, No. 5 ( 2019-09), p. 654-655
    Type of Medium: Online Resource
    ISSN: 0300-9858 , 1544-2217
    URL: Article
    DOI: 10.1177/0300985819860205
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2106608-5
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  • 8
    Online Resource
    Online Resource
    Mixed Thymoma in a Cow
    SAGE Publications ; 2006
    In:  Journal of Veterinary Diagnostic Investigation Vol. 18, No. 5 ( 2006-09), p. 503-507
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 18, No. 5 ( 2006-09), p. 503-507
    Abstract: A neoplastic mass measuring 25 × 8 × 3 cm was found in the mediastinum of a 10-year-old Holstein cow. The neoplasm was encapsulated, multilobulated, and cystic. Several firm adhesions were present between the neoplasm and the right cranial lung lobe and the ipsilateral side of the pericardial sac. Under microscopic examination, the neoplasm was characterized by solid sheets of spindle epithelial cells (pancytokeratin and high molecular weight cytokeratin positive) subdivided by fibrous trabeculae. Numerous individualized or small aggregates of mature T-cell (CD3 positive) lymphocytes were scattered throughout the neoplastic cell population. Based on the gross, histologic, and immunohistochemical findings, the neoplasm was diagnosed as a mixed thymoma.
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/104063870601800518
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2006
    detail.hit.zdb_id: 2265211-5
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  • 9
    Online Resource
    Online Resource
    Fatal Canid herpesvirus 1 infection in an adult dog
    SAGE Publications ; 2012
    In:  Journal of Veterinary Diagnostic Investigation Vol. 24, No. 3 ( 2012-05), p. 604-607
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 24, No. 3 ( 2012-05), p. 604-607
    Abstract: Canid herpesvirus 1 (CaHV-1) is a well-known cause of fatal hepatic and renal necrosis in neonatal puppies. In adult dogs infected with CaHV-1, papulovesicular genital lesions may be observed. CaHV-1 infection during pregnancy can lead to embryonic resorption, abortion, and stillbirth. In high-density dog populations, CaHV-1 can also contribute to kennel cough. Furthermore, recent literature has clearly documented that CaHV-1 can induce ocular disease in immature and adult dogs. The current study describes a case of fatal CaHV-1 infection in a 9-year-old spayed female Bichon Frise dog. Following a history of vomiting and diarrhea, the dog deteriorated and subsequently died. The main lesions were multifocal areas of necrosis with intranuclear inclusion bodies in the liver, adrenal gland, and small intestine, similar to the lesions observed in CaHV-1-infected puppies. Infection with CaHV-1 was confirmed on samples of liver by polymerase chain reaction, immunohistochemistry, and in situ hybridization. There was no indication of immunosuppression in this dog. Based on the results presented herein, CaHV-1 should be included in the list of differential diagnoses of hepatic necrosis in adult dogs.
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/1040638712440994
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2265211-5
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  • 10
    Online Resource
    Online Resource
    A retrospective histologic study of 140 cases of clinically significant equine ocular disorders
    SAGE Publications ; 2020
    In:  Journal of Veterinary Diagnostic Investigation Vol. 32, No. 3 ( 2020-05), p. 382-388
    Details
    In: Journal of Veterinary Diagnostic Investigation, SAGE Publications, Vol. 32, No. 3 ( 2020-05), p. 382-388
    Abstract: Ocular diseases are an important category in equine medicine; however, most articles regarding histologic ocular lesions in horses are exclusive to a specific condition and do not provide a complete review of clinically significant ocular disease frequency in a diagnostic laboratory. We reviewed sections of equine eyes from 140 cases (98 enucleations [biopsies] and 42 autopsies) with clinically relevant ocular alterations at 2 diagnostic centers in the United States. The most common primary conditions were non-traumatic keratitis (36), equine recurrent uveitis (ERU; 31), traumatic injuries (22), ocular and periocular neoplasms (19), and uveitis and/or endophthalmitis resulting from sepsis (18). Congenital anomalies (3) and retinal atrophy and detachment alone (3) were infrequent. Non-traumatic keratit is was frequently accompanied by anterior uveitis (22), corneal rupture (16), pre-iridal fibrovascular membrane formation (13), and secondary mycotic infection (11). ERU was the second and third most prevalent disease in autopsies and enucleations, respectively. This condition was commonly associated with glaucoma (15). Glaucoma (25) and cataract (20) were the most prevalent secondary alterations in the evaluated cases. Keratitis (20) and corneal rupture (16) were among the most prevalent consequences of trauma. Information presented herein may guide clinicians and pathologists, contributing to the early diagnosis of potentially vision-impairing conditions and raising the chances of successful treatment and cure.
    Type of Medium: Online Resource
    ISSN: 1040-6387 , 1943-4936
    URL: Article
    DOI: 10.1177/1040638720912698
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2265211-5
    SSG: 22
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