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  • 1
    Online Resource
    Online Resource
    Aluminum metal composites primed by fused deposition modeling-assisted investment casting: Hardness, surface, wear, and dimensional properties
    SAGE Publications ; 2021
    In:  Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications, SAGE Publications
    Abstract: Fused deposition modeling -based three-dimensional printing techniques, when merged with the investment casting process, is one of the most innovative techniques for developing functionally graded metal–matrix composites in high-performance industrial applications. In this study, Al–Al 2 O 3 matrix composites have been prepared by the combined route of fused deposition modeling and modified investment casting processes. In the first step, the Al–Al 2 O 3 particles have been reinforced into nylon 6 thermoplastics for the preparation of fused deposition modeling-based feedstock filaments (in two configurations: C1 (60% nylon 6–30% Al–10% Al 2 O 3 ) and C2 (60% nylon 6–28% Al–12% Al 2 O 3 ). In the next step, the investment casting patterns of the fused deposition modeling process of nylon 6–Al–Al 2 O 3 composites were prepared. Furthermore, the investment casting has been performed by controlling the proportion of nylon 6–Al–Al 2 O 3 , the volume of pattern, the density of pattern, barrel finishing media weight, barrel fining time, and number of mold wall layers considering Taguchi L 18 -based experimental design. Finally, the functional aluminum matrix composites were subjected to testing to investigate average surface roughness ( R a ), deviation inside the cube, average wear, and average hardness. The study results have suggested that maintaining a higher proportion of Al 2 O 3 in three-dimensional printed parts leads to higher R a , higher dimensional deviation, and higher hardness of investment cast parts. On the contrary, solid patterns have provided low wear rates and low-density patterns resulting in increased wear rates in final investment casted products. Furthermore, the responses are optimized concurrently with the “technique for order of preference by similarity to ideal solution–Taguchi” technique while considering the analytical hierarchical process and entropy weights of significance.
    Type of Medium: Online Resource
    ISSN: 1464-4207 , 2041-3076
    URL: Article
    DOI: 10.1177/14644207211054143
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2032772-9
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  • 2
    Online Resource
    Online Resource
    Guinness world record attempt as a method to pivot the role of Yoga in Diabetes management
    SAGE Publications ; 2019
    In:  Annals of Neurosciences Vol. 26, No. 1 ( 2019-01), p. 21-24
    Details
    In: Annals of Neurosciences, SAGE Publications, Vol. 26, No. 1 ( 2019-01), p. 21-24
    Type of Medium: Online Resource
    ISSN: 0972-7531 , 0976-3260
    URL: Article
    DOI: 10.5214/ans.0972.7531.260105
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2576191-2
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  • 3
    Online Resource
    Online Resource
    Podophyllum hexandrum Fraction (REC-2006) Shows Higher Radioprotective Efficacy in the p53-Carrying Hepatoma Cell Line: A Role of Cell Cycle Regulatory Proteins
    SAGE Publications ; 2009
    In:  Integrative Cancer Therapies Vol. 8, No. 3 ( 2009-09), p. 261-272
    Details
    In: Integrative Cancer Therapies, SAGE Publications, Vol. 8, No. 3 ( 2009-09), p. 261-272
    Abstract: The present study was carried out to evaluate the radioprotective efficacy of Podophyllum hexandrum fraction (REC-2006) in hepatoma cell lines having different p53 statuses. Higher radioresistance was observed in the HepG2 (p53 ++ ) cell line in comparison to the Hep3B (p53 -- ) cell line, indicating a plausible role of p53 in radioresistance. REC-2006 exhibited nearly twice the survival in p53-expressing HepG2 cells compared with p53-negative Hep3B cells. REC-2006 treatment alone induced p53 expression as compared with untreated controls. However, REC-2006 reduced p53 expression when treated 2 hours before irradiation as compared with the irradiated HepG2 controls, indicating that REC-2006 modulates the expression of p53 to mitigate its apoptotic effect. Induction of p21 in the REC-2006 + radiation treatment group downregulated the expression of cyclin E and CDK2, leading to a delay in the G1 phase of HepG2 cells, which provided time for DNA repair or related processes. However, no significant difference in CDC2 expression in both cell lines suggested that G2 phase arrest might not be the only responsible factor for REC-2006-mediated radioprotection. Significant induction of PCNA and GADD45 expression in HepG2 cells suggested that REC-2006 increased the percentage survival of HepG2 cells by increasing the span of time as well as efficacy for repair processes. In conclusion, REC-2006 modulated the expression of p53 and thereby promoted cell cycle arrest in the G1 phase, encouraging cell proliferation and DNA repair and thus providing significantly higher protection against acute γ-radiation in the HepG2 cell line.
    Type of Medium: Online Resource
    ISSN: 1534-7354 , 1552-695X
    URL: Article
    DOI: 10.1177/1534735409343589
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 2101248-9
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  • 4
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    Online Resource
    Hybrid additive manufacturing of highly sustainable Polylactic acid -Carbon Fiber-Polylactic acid sandwiched composite structures: Optimization and machine learning
    SAGE Publications ; 2023
    In:  Journal of Thermoplastic Composite Materials
    Details
    In: Journal of Thermoplastic Composite Materials, SAGE Publications
    Abstract: Carbon fibre (CF) based polymeric composites are being used in automobile and aviation applications due to their lightweight, excellent mechanical and physical properties. In this study, the fused filament fabrication (FFF) technique was used to prepare composite structures of polylactic acid (PLA) sandwiched with CF layers followed by prediction of optimum setting by machine learning (ML). In the first stage, PLA-CF-PLA based composite structures (as per ASTM D638 type IV) were manufactured with deposition of fibre at various angles (0°, 45° and 90°), nozzle temperature (200°C, 205°C and 210°C) and bed temperature (55°C, 60°C and 65°C). Further, the prepared composite structures were subjected to tensile testing (strength at peak and break, strain at peak and break, Young’s modulus and modulus of toughness) followed by fracture analysis through a scanning electron microscope (SEM) energy-dispersive spectroscopy (EDS). The results of the study are supported by X-ray diffraction (XRD), Fourier transforms infrared spectroscopy (FTIR) analysis, and differential scanning calorimetry (DSC). In the second stage, Classification and Regression Trees (CART) of the ML approach were used to model strength at peak and strength at break. The results of the study have highlighted that combination of parameters, 0˚orientation of CF deposition, 205°C nozzle temperature, and 55°C bed temperature are the optimum settings for manufacturing PLA-CF composite structures. The ML CART model is a valuable tool for predicting the strength at peak and strength at break hybrid additive manufacturing of highly sustainable PLA-CF-PLA sandwiched composite structures.
    Type of Medium: Online Resource
    ISSN: 0892-7057 , 1530-7980
    URL: Article
    DOI: 10.1177/08927057231180186
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2098671-3
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  • 5
    Online Resource
    Online Resource
    Metal spray layered hybrid additive manufacturing of PLA composite structures: Mechanical, thermal and morphological properties
    SAGE Publications ; 2022
    In:  Journal of Thermoplastic Composite Materials Vol. 35, No. 10 ( 2022-10), p. 1387-1407
    Details
    In: Journal of Thermoplastic Composite Materials, SAGE Publications, Vol. 35, No. 10 ( 2022-10), p. 1387-1407
    Abstract: The fusion of additive layers is the primary concern, which affects the mechanical properties of the three-dimensional printed structures prepared by material extrusion-based additive manufacturing (MEAM) process. To promote the fusion and strength between the thermoplastic layers during MEAM process, the metal spray in between the additive layers is used as a novel approach. In this study, aluminium (Al) spray has been deposited in between the polylactic acid structures to enhance the bonding of the additive layers. The methodology includes deposition of 1, 3 and 5 Al spray layers at periodic time intervals with varying infill percentage (40%, 70% and 100%) and bed temperature (60°C, 80°C and 100°C). The structures have been subjected to flexural testing for investigation of the role of each input process parameter followed by fracture morphology analysis through scanning electron microscopy and energy-dispersive spectroscopy. The results of the study suggested that the maximum flexural strength is possible with five spray layers, 70% infill and 100°C bed temperature.
    Type of Medium: Online Resource
    ISSN: 0892-7057 , 1530-7980
    URL: Article
    DOI: 10.1177/0892705720932622
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2098671-3
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  • 6
    Online Resource
    Online Resource
    Management of hunger strike: A medical, ethical and legal conundrum
    SAGE Publications ; 2020
    In:  Medico-Legal Journal Vol. 88, No. 4 ( 2020-12), p. 215-219
    Details
    In: Medico-Legal Journal, SAGE Publications, Vol. 88, No. 4 ( 2020-12), p. 215-219
    Abstract: Hunger strike is a protest where an informed person refuses essential nourishment with the intention of accomplishing a specific goal. Hunger strikes conflict with medical, ethical, humanitarian and legal values. A multidisciplinary approach is important when dealing with hunger strike patients. On one hand, there is the wish to preserve life, and on the other to respect the strikers’ autonomy and their wishes, values and advanced directives (or living will). Most hunger strikes are short-lived, but in complex and prolonged circumstances, legal advice must be sought from health service solicitors and a doctor’s medical indemnity organisation. There is an emergent need to have defined guidelines for the management of these hunger strikes to be followed.
    Type of Medium: Online Resource
    ISSN: 0025-8172 , 2042-1834
    URL: Article
    DOI: 10.1177/0025817220923653
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2545609-X
    SSG: 2
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  • 7
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    Online Resource
    Nutritional Assessment in Chronic Kidney Disease Patients in the Bundelkhand Region (Uttar Pradesh), India
    SAGE Publications ; 2023
    In:  Indian Journal of Clinical Medicine Vol. 13, No. 1 ( 2023-06), p. 11-16
    Details
    In: Indian Journal of Clinical Medicine, SAGE Publications, Vol. 13, No. 1 ( 2023-06), p. 11-16
    Abstract: This research aimed to assess the nutritional intake and anthropometry of patients presenting with CKD in a hospital clinic. Methods The study was carried out on 100 CKD patients who were on maintenance hemodialysis at Maharani Laxmi Bai Medical College, Jhansi, Uttar Pradesh, India. The patient’s file was inspected to get the relevant anthropometric and biochemical data. The information was gathered using a pre-designed proforma. Results The study included 100 CKD patients with a mean age of 45.74 ± 14.93 years. Males outnumber females, with a male-to-female ratio of 6.69:1. The mean calorie and protein given to the CKD patients (according to body weight) are 1657.60 ± 240.179 and 71.75 ± 77.165, respectively. The mean weight, BMI, and MUAC of the CKD patient were 57.371±6.22, 21.56 ± 1.705, and 23.86 ± 1.709, respectively. After 3 months of nutritional assessment, the patient’s mean weight, BMI, and MUAC were increased. The mean cholesterol, Triglyceride, HDL, VLDL, and RBS levels of the CKD patient were 163.90 ± 29.75, 139.76 ± 35.72, 49.46 ± 6.29, 28.488 ± 7.114, and 117.65 ± 21.46, respectively. After three months of the nutritional assessment, the patient’s mean cholesterol, Triglyceride, HDL, and VLDL levels increased while RBS level decreased. The CKD patient’s mean S. creatinine and S. albumin levels were 9.97 ± 3.453 and 3.285 ± 0.531, respectively. After 3 months of nutritional assessment, the patient’s mean S. creatinine and S. albumin levels increased to 10.4231 ± 3.420 and 4.056 ± 5.6389, respectively. Conclusion The nutritional diet influences body weight, BMI, and biochemical indicators. Low energy and protein intake was reported; hence, educating patients, co-patients, and families about the essential foods that fulfill the recommended intake for CKD patients is required. Follow-up patients showed better nutritional knowledge as compared with baseline patients.
    Type of Medium: Online Resource
    ISSN: 2633-9447 , 1179-9161
    URL: Article
    DOI: 10.1177/26339447221148890
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2683222-7
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  • 8
    Online Resource
    Online Resource
    Employee Engagement : Explicating the Contribution of Work Environment
    SAGE Publications ; 2012
    In:  Management and Labour Studies Vol. 37, No. 1 ( 2012-02), p. 31-43
    Details
    In: Management and Labour Studies, SAGE Publications, Vol. 37, No. 1 ( 2012-02), p. 31-43
    Abstract: Employee engagement at work can be referred to as the harnessing of organizational members’ selves to their work roles. In engagement people employ and express themselves physically, cognitively and emotionally (Kahn, 1990). Through the present study an attempt has been made to identify the contribution of some antecedents towards employee engagement. Under the antecedents we have taken two relationship-oriented variables (co-worker cohesion and supervisor support), three personal growth variables (autonomy, task orientation and work pressure) and three system maintenance variables (clarity, control and physical comfort). The researchers attempted to investigate the contribution of these antecedent variables towards level of engagement by conducting the study upon 100 semi-skilled employees from food processing organizations situated around Patiala, Punjab. The level of engagement of the employees has been explicated in terms of cognitive, emotional and physical engagement. Stepwise multiple regression analysis has been carried out separately for each of these engagement variables to delineate the contribution of the eight antecedent variables towards them. The finding indicates that two personal growth variables, namely ‘work pressure’ and ‘autonomy’ have significant contribution towards cognitive as well as emotional engagement followed by the contribution of the relationship oriented variables. However, except ‘peer cohesion’, there is no significant contribution of any other variable towards physical engagement. The findings have been discussed in light of related literatures.
    Type of Medium: Online Resource
    ISSN: 0258-042X , 2321-0710
    URL: Article
    DOI: 10.1177/0258042X1103700104
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2657684-3
    SSG: 3,2
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  • 9
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    Online Resource
    Chlorpromazine as Prophylaxis for Bipolar Disorder with Treatment- and Electroconvulsive Therapy-Refractory Mania: Old Horse, New Trick
    SAGE Publications ; 2017
    In:  Indian Journal of Psychological Medicine Vol. 39, No. 4 ( 2017-07), p. 539-541
    Details
    In: Indian Journal of Psychological Medicine, SAGE Publications, Vol. 39, No. 4 ( 2017-07), p. 539-541
    Type of Medium: Online Resource
    ISSN: 0253-7176 , 0975-1564
    URL: Article
    DOI: 10.4103/0253-7176.211759
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2622378-8
    SSG: 5,2
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  • 10
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    Online Resource
    The Creation and Verification of Cranial Models Using Three-dimensional Rapid Prototyping Technology in Field of Transnasal Sphenoid Endoscopy
    SAGE Publications ; 2012
    In:  American Journal of Rhinology & Allergy Vol. 26, No. 5 ( 2012-09), p. e132-e136
    Details
    In: American Journal of Rhinology & Allergy, SAGE Publications, Vol. 26, No. 5 ( 2012-09), p. e132-e136
    Abstract: Surgical navigation systems have been used increasingly in guiding complex ear, nose, and throat surgery. Although these are helpful, they are only beneficial intraoperatively; thus, the novice surgeon will not have the preoperative training or exposure that can be vital in complex procedures. In addition, there is a lack of reliable models to give surgeons hands-on training in performing such procedures. Methods A technique using an industrial rapid prototyping process by three-dimensional (3D) printing was developed, from which accurate spatial models of the nasal cavity, paranasal sinuses (sphenoid sinus in particular), and intrasellar/pituitary pathology were produced, according to the parameters of an individual patient. Image-guided surgical (IGS) techniques on two different platforms were used during endoscopic transsphenoidal surgery to test and validate the anatomical accuracy of the sinus models by comparing the models with radiological images of the patient on IGS. Results It was possible to register, validate, and navigate accurately on these models using commonly available navigation stations, matching accurately the anatomy of the model to the IGS images. Conclusion These 3D models can be reliably used for teaching/training and preoperative planning purposes.
    Type of Medium: Online Resource
    ISSN: 1945-8924 , 1945-8932
    URL: Article
    DOI: 10.2500/ajra.2012.26.3808
    RVK:
    XA 20278
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2554548-6
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