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  • 1
    Online Resource
    Online Resource
    Dynamic simulation of a full vehicle system featuring magnetorheological dampers with bypass holes
    SAGE Publications ; 2020
    In:  Journal of Intelligent Material Systems and Structures Vol. 31, No. 2 ( 2020-01), p. 253-262
    Details
    In: Journal of Intelligent Material Systems and Structures, SAGE Publications, Vol. 31, No. 2 ( 2020-01), p. 253-262
    Abstract: This study suggests a relationship between two different types of magnetorheological dampers and the driving performance of the passenger vehicles such as ride quality and stability. One of the magnetorheological dampers has the two different bypass holes in the piston bobbin to achieve a relatively low damping force slope in the low piston velocity region. Without bypass holes, two cylindrical-type magnetorheological dampers have same dimensions (pole lengths, piston radius, and coil size). To enhance the ride quality of the passenger vehicle, the damping force slope of the magnetorheological damper with bypass holes is more gradual than that of the magnetorheological damper without bypass holes. On the basis of the damping force model, three vehicle types with two working modes (soft and hard) are formulated. Driving performance indexes, such as vertical acceleration of the sprung mass and tire deflection, are evaluated in frequency domains under two random road conditions. A comparative study is conducted to prove the effectiveness of the magnetorheological damper with bypass holes through simulation.
    Type of Medium: Online Resource
    ISSN: 1045-389X , 1530-8138
    URL: Article
    DOI: 10.1177/1045389X19876880
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2088313-4
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  • 2
    Online Resource
    Online Resource
    Electronic Moxibustion for Breast Cancer-Related Lymphedema: A Pilot Clinical Trial
    SAGE Publications ; 2020
    In:  Integrative Cancer Therapies Vol. 19 ( 2020-01), p. 153473542096285-
    Details
    In: Integrative Cancer Therapies, SAGE Publications, Vol. 19 ( 2020-01), p. 153473542096285-
    Abstract: This is a preliminary study to investigate the feasibility of electronic moxibustion in breast cancer patients with upper limb lymphedema. As current treatment options for lymphedema are unsatisfactory and time consuming, there have been attempts to manage symptoms using integrative treatments. Electronic moxibustion was developed to compensate for the shortcomings of conventional moxibustion and is widely used in clinical practice. However, there have been no studies on using electronic moxibustion in breast cancer-related lymphedema. To investigate the feasibility of electronic moxibustion in treating breast cancer-related lymphedema, this study included subjects who completed primary cancer treatment at least 6 months ago and had more than 10 mm difference in arm circumference of upper limbs. All subjects were assigned to the treatment group. Subjects were treated with 16 sessions (30 minutes/session) of electronic moxibustion for 8 weeks followed by 4 weeks of follow-up. For outcome measures, upper limb circumferences, shoulder range of motion, bioimpedance analysis, and quality of life questionnaire were assessed. All 10 subjects completed the study. The effective index showed 38.21% reduction after treatment ( P = .0098) and 29.35% ( P = .0039) after 4 weeks of follow-up compared to the baseline. The reduction of lymphedema was most prominent at 10 cm above the elbow crease, where the mean reduction of circumference difference was 7.5 mm ( P = .0430) and continued to improve after treatment (mean reduction of 8.3 mm, P = .0156). There was significant improvement in shoulder range of motion only in flexion and internal rotation at week 9. There were 7 adverse events, and most were irrelevant to the treatment. Only 1 participant had a mild burn on the acupuncture point. Here, we demonstrate for the first time that electronic moxibustion treatment is a feasible treatment for breast cancer-related lymphedema. Electronic moxibustion may reduce differences in upper limb circumference and improve shoulder range of motion. A future comparative clinical trial is needed to confirm the clinical efficacy of this treatment.
    Type of Medium: Online Resource
    ISSN: 1534-7354 , 1552-695X
    URL: Article
    DOI: 10.1177/1534735420962854
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2101248-9
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  • 3
    Online Resource
    Online Resource
    Asiatic Acid Derivatives Protect Primary Cultures of Rat Hepatocytes against Carbon Tetrachloride-Induced Injury via the Cellular Antioxidant System
    SAGE Publications ; 2009
    In:  Natural Product Communications Vol. 4, No. 6 ( 2009-06), p. 1934578X0900400-
    Details
    In: Natural Product Communications, SAGE Publications, Vol. 4, No. 6 ( 2009-06), p. 1934578X0900400-
    Abstract: We attempted to elucidate the hepatoprotective mechanism of two asiatic acid (AS) derivatives, 3β,23-dihydroxyurs-2-oxo-12-ene-28-oic acid (AS-10) and 3β,23-dihydroxyurs-12-ene-28-oic acid (AS-14), which exhibited significant protective activity against carbon tetrachloride (CCl 4 )-induced hepatotoxicity in primary cultures of rat hepatocytes. Our findings showed that AS-10 and AS-14 preserved the level of glutathione and the activities of antioxidant enzymes such as glutathione reductase, glutathione peroxidase, superoxide dismutase and catalase. In addition, these compounds ameliorated lipid peroxidation, as demonstrated by a reduction in the production of malondialdehyde. Furthermore, AS-10 and AS-14 did not restore the reduced total GSH level by BSO, indicating that the hepatoprotective activities of these compounds may be involved, in part, by regulating GSH synthesis. From these results, we suggest that both AS-10 and AS-14 exerted their hepatoprotective activities against CCl 4 -induced injury by preserving the cellular antioxidative defense system.
    Type of Medium: Online Resource
    ISSN: 1934-578X , 1555-9475
    URL: Article
    DOI: 10.1177/1934578X0900400605
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 2430442-6
    SSG: 15,3
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  • 4
    Online Resource
    Online Resource
    Tumor Volume Reduction Assessed by Planning Computed Tomography in Patients with Rectal Cancer during Preoperative Chemoradiation: Impact of Residual Tumor Volume on the Prediction of Pathologic Tumor Regression
    SAGE Publications ; 2014
    In:  Tumori Journal Vol. 100, No. 2 ( 2014-03), p. 158-162
    Details
    In: Tumori Journal, SAGE Publications, Vol. 100, No. 2 ( 2014-03), p. 158-162
    Abstract: To determine whether the residual tumor volume measured using the Eclipse treatment planning system correlates with pathologic tumor regression grade after preoperative chemoradiotherpy for rectal cancer. Materials and Methods The study included 30 patients with rectal cancer who had undergone preoperative chemoradiotherpy followed by surgery from June 2008 to April 2011 at the Korea University Guro Hospital. The tumor volume was measured using the Eclipse treatment planning system in the initial simulation computed tomography and boost planning computed tomography. The correlation between the residual tumor volume in boost planning computed tomography and the pathologic tumor regression grade was analyzed. Tumor regression grade defined in the American Joint Committee on Cancer 7th edition was used. Results The mean and median residual tumor volume was 57.34% ± 20.37% and 52.35% (range, 18.42%-95.79%), respectively. After surgery, pathologic complete response (tumor regression grade 0) occurred in 4 patients (13.33%), moderate response (tumor regression grade 1) in 18 patients (60%), minimal response (tumor regression grade 2) in 4 patients (13.33%), and poor response (tumor regression grade 3) in 4 patients (13.33%). When residual tumor volume was categorized into two groups ( 〈 50% and ≥50%), complete or moderate regression (tumor regression grade 0 or 1) was significantly greater for patients with a residual tumor volume 〈 50% (P 〈 0.05). The mean residual tumor volume of tumor regression grade 0 or 1 was 49.07% ± 18.39% and that of tumor regression grade 2 or 3 was 76.31% ± 16.94% (P 〈 0.05). Conclusions Residual tumor volume measured using routine boost planning computed tomography during preoperative chemoradiotherpy correlated significantly with pathologic tumor regression grade after surgery.
    Type of Medium: Online Resource
    ISSN: 0300-8916 , 2038-2529
    URL: Article
    DOI: 10.1177/030089161410000207
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 280962-X
    detail.hit.zdb_id: 2267832-3
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  • 5
    Online Resource
    Online Resource
    The effects of prearrival direct notification call to interventional cardiologist on door-to-balloon time in patients who required secondary diversion with ST-elevation myocardial infarction for primary percutaneous coronary intervention
    SAGE Publications ; 2019
    In:  Hong Kong Journal of Emergency Medicine Vol. 26, No. 3 ( 2019-05), p. 165-173
    Details
    In: Hong Kong Journal of Emergency Medicine, SAGE Publications, Vol. 26, No. 3 ( 2019-05), p. 165-173
    Abstract: Rapid door-to-balloon times in ST-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention are associated with favorable outcomes. Objectives: We evaluated the effects of prearrival direct notification calls to interventional cardiologists on door-to-balloon time for ST-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention. Methods: A 24-h hotline was created to allow prearrival direct notification calls to interventional cardiologists when transferring ST-elevation myocardial infarction patients. In an urban, tertiary referral center, patients who visited via inter-facility or the emergency department directly were included. Clinical parameters, time to reperfusion therapy, and in-hospital mortality were compared between patients with and without prearrival notifications. Results: Of 228 ST-elevation myocardial infarction patients, 95 (41.7%) were transferred with prearrival notifications. In these patients, door-to-balloon time was shorter (50.0 vs 60.0 min, p = 0.010) and the proportion of patients with door-to-balloon time  〈  90 min was higher (89.5% vs 75.9%, p = 0.034) than patients without notifications. These improvements were more pronounced during “off-duty” hours (52.0 vs 78.0 min, p = 0.001; 88.3% vs 72.3%, p = 0.047, respectively) than during “on-duty” hours (37.5 vs 43.5 min, p = 0.164; 94.4% vs 79.4%, p = 0.274, respectively). In addition, door-to-activation time (–39 vs 11 min, p  〈  0.001) and door-to-catheterization laboratory arrival time (33 vs 42 min, p = 0.007) were shorter in patients with prearrival notifications than those without. However, in-hospital mortality was similar between the two groups (6.3% vs 6.8%, p = 0.892). Conclusion: Prearrival direct notification calls to interventional cardiologists significantly improved the door-to-balloon time and the proportion of patients with door-to-balloon time 〈  90 min through rapid patient transport in primary percutaneous coronary intervention scheduled hospital and readiness of the catheterization laboratory.
    Type of Medium: Online Resource
    ISSN: 1024-9079 , 2309-5407
    URL: Article
    DOI: 10.1177/1024907918794782
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2917387-5
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  • 6
    Online Resource
    Online Resource
    Waterborne polyurethane modified with silicone macromer and the nylon airbag coated with it
    SAGE Publications ; 2016
    In:  Textile Research Journal Vol. 86, No. 19 ( 2016-11), p. 2015-2021
    Details
    In: Textile Research Journal, SAGE Publications, Vol. 86, No. 19 ( 2016-11), p. 2015-2021
    Abstract: A waterborne polyurethane (WPU) with a double bond in the main chain was modified with a poly(dimethylsiloxane) (PDMS) macromer having a terminal methacrylate group (PDMS methacrylate macromer) by using a radical mechanism, and the changes in various physical properties were examined. Although the crystallinity of the soft segment domain increased, the cohesion of the hard segments was weakened as a result of the modification with the PDMS methacrylate macromer. The adhesion between the WPU and nylon decreased due to the hydrophobic/low polarity of the PDMS component, and this improved the flexibility and the tear strength of the nylon-6,6 textile coated with WPU. The air permeability of the coated textile also increased as a result of the modification.
    Type of Medium: Online Resource
    ISSN: 0040-5175 , 1746-7748
    URL: Article
    DOI: 10.1177/0040517515619352
    RVK:
    ZS 0001
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2209596-2
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