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  • 1
    Online Resource
    Online Resource
    The effects of a multispecies probiotic supplement on inflammatory markers and episodic and chronic migraine characteristics: A randomized double-blind controlled trial
    SAGE Publications ; 2019
    In:  Cephalalgia Vol. 39, No. 7 ( 2019-06), p. 841-853
    Details
    In: Cephalalgia, SAGE Publications, Vol. 39, No. 7 ( 2019-06), p. 841-853
    Abstract: The current study was designed to assess the effect of supplementation with a 14-strain probiotic mixture on episodic and chronic migraine characteristics. Methods Forty episodic and 39 chronic migraine patients who completed this randomized double-blind controlled trial received two capsules of multispecies probiotic or placebo. The migraine severity was assessed by visual analog scale (VAS). The number of abortive drugs consumed, migraine days, frequency and duration of attacks were recorded on paper-based headache diaries. Serum tumor necrosis factor alpha (TNF-α) and C- reactive protein (CRP) levels were measured at baseline and the end of the intervention. Results After a 10-week intervention, among episodic migraineurs the mean frequency of migraine attacks significantly reduced in the probiotic group compare to the placebo group (mean change: −2.64 vs. 0.06; respectively, p  〈  0.001). A significant reduction was also evident in the migraine severity (mean decrease: −2.14 in the probiotic group and 0.11 in the placebo group; p  〈  0.001). Episodic migraineurs who received the probiotic also showed significant reduction in abortive drug usage per week (mean change: −0.72; p  〈  0.001) compare to baseline, while there was no significant changes within the placebo group. In chronic migraine patients, after an 8-week intervention, the mean frequency of migraine attacks significantly reduced in the probiotic compared to the placebo group (mean change: −9.67 vs. −0.22; p ≤ 0.001). In contrast to the placebo, probiotic supplementation significantly decreased the severity (mean changes: −2.69; p ≤ 0.001), duration (mean changes: −0.59; p ≤ 0.034) of attacks and the number of abortive drugs taken per day (mean changes: −1.02; p  〈  0.001), in chronic migraine patients. We failed to detect any significant differences in the serum levels of inflammatory markers at the end of the study either in chronic or in episodic migraineurs. Discussion The results of this study showed that the 14-strain probiotic mixture could be an effective and beneficial supplement to improve migraine headache in both chronic and episodic migraineurs. Further research is required to confirm our observations.
    Type of Medium: Online Resource
    ISSN: 0333-1024 , 1468-2982
    URL: Article
    DOI: 10.1177/0333102418820102
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2019999-5
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  • 2
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    Do Adventitial Mast Cells Contribute to the Pathogenesis of Ascending Thoracic Aorta Aneurysm?
    SAGE Publications ; 2012
    In:  International Journal of Surgical Pathology Vol. 20, No. 5 ( 2012-10), p. 474-479
    Details
    In: International Journal of Surgical Pathology, SAGE Publications, Vol. 20, No. 5 ( 2012-10), p. 474-479
    Abstract: The precise pathogenesis of the ascending aortic aneurysm (AscAA) remains to be determined. Mast cells in the adventitia of human AscAA lesions may play a role in this pathogenesis. Adventitial mast cell density per 10 high-power fields (0.25 mm 2 ) was assessed in multiple biopsy samples, from aneurysmal aortic sections (n = 41) and control (nondilated) aortic specimens (n = 50), stained by orcein-Giemsa method, an inexpensive ( 〈 $1) method. In a multivariable adjusted logistic regression model, using AscAA as the dependent variable, mast cell density was found to be an independent predictor of AscAA occurrence (odds ratio = 2.21; 95% confidence interval = 1.58-3.08; P 〈 .001). Receiver operating characteristic curve analysis showed that the proposed cutoff value of ≥3 mast cells per 10 high-power fields was very sensitive to detect AscAA occurrence, yielding a sensitivity of 90% with a specificity of 80%. In conclusion, a significant increase in the number of mast cells in the adventitia of human ascending aortic lesions proposes a role for these cells in the pathogenesis of AscAA.
    Type of Medium: Online Resource
    ISSN: 1066-8969 , 1940-2465
    URL: Article
    DOI: 10.1177/1066896912440820
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2070102-0
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  • 3
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    Qeirat Values and Victim Blaming in Iran: The Mediating Effect of Culture-Specific Gender Roles
    SAGE Publications ; 2023
    In:  Journal of Interpersonal Violence Vol. 38, No. 3-4 ( 2023-02), p. 2485-2509
    Details
    In: Journal of Interpersonal Violence, SAGE Publications, Vol. 38, No. 3-4 ( 2023-02), p. 2485-2509
    Abstract: Sexual assaults are a social problem in Iran; however, psychological factors that predict perceptions of sexual assault remain largely unexamined. Here, we examine the relationship between moral concerns, culture-specific gender roles, and victim blaming in sexual assault scenarios in Iranian culture. Relying on Moral Foundations Theory and recent theoretical developments in moral psychology in the Iranian context, we examined the correlations between five moral foundations (Care, Fairness, Loyalty, Authority, and Purity), a culture-specific set of values called Qeirat (which includes guarding and [over]protectiveness of female kin, romantic partners, broader family, and country), and victim blaming. In a community sample of Iranians ( N = 411), we found Qeirat values to be highly correlated with victim blaming, and that this link was mediated by a number of culture-specific proscriptions about women’s roles and dress code (i.e., Haya). In a regression analysis with all moral foundations, Qeirat values, Haya, and religiosity as predictors of victim blaming, only Haya, religiosity, high Authority values, and low Care values were found to predict how strongly Iranian participants blamed victims of sexual assault scenarios.
    Type of Medium: Online Resource
    ISSN: 0886-2605 , 1552-6518
    URL: Article
    DOI: 10.1177/08862605221101184
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2028900-5
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  • 4
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    Acute pesticide poisoning and related factors among farmers in rural Western Iran
    SAGE Publications ; 2018
    In:  Toxicology and Industrial Health Vol. 34, No. 11 ( 2018-11), p. 764-777
    Details
    In: Toxicology and Industrial Health, SAGE Publications, Vol. 34, No. 11 ( 2018-11), p. 764-777
    Abstract: Although acute pesticide poisoning (APP) is known to be a major health concern among farmers in developing countries, knowledge of its prevalence and risk factors is limited. The purpose of this study was to investigate the prevalence and a broad range of potential work-related risk factors of APP among Iranian farmers and farm workers. This cross-sectional study was conducted in rural areas of the Twiserkan County in Iran. In this study, there were 474 farmers and farm workers who had used pesticide 1 week before data collection. Participants were selected from 104 villages. Data were gathered using a questionnaire and analyzed using STATA (version 14.2 SE). Binary logistic regression and multinomial logistic regression were employed. The results of this study showed that 286 (60.3%) farmers and farm workers who applied pesticides suffered from work-related APP. Most frequent APP symptoms were runny nose (29.8%) and headache (25.1%). Five risk factors were identified, including annual income ( p 〈 0.05), number of farming years (odds ratio (OR) = 0.31), number of spraying years (OR = 2.40), place of pesticide storage (OR = 2.69), and type of sprayer ( p 〈 0.05). The results of this study indicated that APP is prevalent among the studied farmers. Some work-related factors play an important role in APP among Iranian rural farmers. In addition, the magnitude of these risk factors differed significantly by severity of acute and somatic pesticide poisoning.
    Type of Medium: Online Resource
    ISSN: 0748-2337 , 1477-0393
    URL: Article
    DOI: 10.1177/0748233718795732
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2010891-6
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  • 5
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    Examining the Built Environment for Healthy Living via Virtual Street Audits
    SAGE Publications ; 2022
    In:  Environmental Health Insights Vol. 16 ( 2022-01), p. 117863022211046-
    Details
    In: Environmental Health Insights, SAGE Publications, Vol. 16 ( 2022-01), p. 117863022211046-
    Abstract: During the fall 2019 and spring 2020 semesters, 156 MPH students enrolled in the Integrative Learning Experience at the University of Alabama at Birmingham School of Public Health explored concepts of the built environment and health by auditing 2500 street segments in 4 urban neighborhoods in Birmingham, Alabama. In teams of 4 to 5, in-class and online students worked collaboratively to assess 63 built environment variables related to transportation, land use, advertisement, and neighborhood physical disorder. This type of “community assessment” is the first stage of the Evidence-based Public Health Framework and consistent with the applied nature of an MPH degree. Authors conducted secondary data analysis of final team assignments to demonstrate how students translated observations and ratings into practical recommendations for neighborhood improvements to promote physical activity. Students recommended improvements in neighborhood infrastructure and services, specifically: creating exercise space, providing outdoor exercise equipment, improving neighborhood safety, and cultivating a culture of health. The Integrative Learning Experience course encouraged students to use their knowledge and skills to prioritize recommendations to improve neighborhood conditions. Variable ratings and observations increased student awareness of the built environment and its potential to impact individual and community health. Moreover, the project helped students make connections between proximal outcomes, such as improving neighborhood walkability, and distal outcomes, such as improved health outcomes among residents. Finally, this project modeled for students the use of evidence-based strategies for making data-informed decisions, which are essential skills for new and emerging public health professionals.
    Type of Medium: Online Resource
    ISSN: 1178-6302 , 1178-6302
    URL: Article
    DOI: 10.1177/11786302221104653
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2452946-1
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  • 6
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    Application of ultrasound-assisted emulsification microextraction for simultaneous determination of aminophenol isomers in human urine, hair dye, and water samples using high-performance liquid chromatography
    SAGE Publications ; 2014
    In:  Human & Experimental Toxicology Vol. 33, No. 8 ( 2014-08), p. 863-872
    Details
    In: Human & Experimental Toxicology, SAGE Publications, Vol. 33, No. 8 ( 2014-08), p. 863-872
    Abstract: Aminophenol isomers (2-, 3-, and 4-aminophenols) are typically classified as industrial pollutants with genotoxic and mutagenic effects due to their easy penetration through the skin and membranes of human, animals, and plants. In the present study, a simple and efficient ultrasound-assisted emulsification microextraction procedure coupled with high-performance liquid chromatography with ultraviolet detector was developed for preconcentration and determination of these compounds in human fluid and environmental water samples. Effective parameters (such as type and volume of extraction solvent, pH and ionic strength of sample, and ultrasonication and centrifuging time) were investigated and optimized. Under optimum conditions (including sample volume: 5 mL; extraction solvent: chloroform, 80 µL; pH: 6.5; without salt addition; ultrasonication: 3.5 min; and centrifuging time: 3 min, 5000 rpm min −1 ), the enrichment factors and limits of detection were ranged from 42 to 51 and 0.028 to 0.112 µg mL −1 , respectively. Once optimized, analytical performance of the method was studied in terms of linearity (0.085–157 µg mL −1 , r 2   〉  0.998), accuracy (recovery = 88.6– 101.7%), and precision (repeatability: intraday precision  〈  3.98%, and interday precision  〈  5.12%). Finally, applicability of the method was evaluated by the extraction and determination of these compounds in human urine, hair dye, and real water samples.
    Type of Medium: Online Resource
    ISSN: 0960-3271 , 1477-0903
    URL: Article
    DOI: 10.1177/0960327113499166
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 1483723-7
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  • 7
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    Impact of miRNA-binding site polymorphisms in STAT3 gene on occurrence and clinical characteristics of systemic lupus erythematosus
    SAGE Publications ; 2022
    In:  Lupus Vol. 31, No. 3 ( 2022-03), p. 338-346
    Details
    In: Lupus, SAGE Publications, Vol. 31, No. 3 ( 2022-03), p. 338-346
    Abstract: Signal transducer and activator of transcription 3 (STAT3) is a major regulator of immune response and chronic inflammatory conditions acting through regulation of B cells, T-helper 17 (Th17) cells, and IL-17 production. Previous studies have demonstrated that dysregulation of STAT3 is crucial for SLE pathogenesis and disease severity. It is believed that single nucleotide polymorphisms (SNPs) located at the 3′-UTR sequence of the target genes could dysregulate their expression by disrupting the binding site of miRNAs. In the present study, we assessed the possible association between rs1053005 and rs1053023 SNPs at miRNA binding sites in the STAT3 gene and the risk of SLE in the Iranian population for the first time. Methods 112 SLE cases and 120 healthy controls were genotyped for rs1053005 (A 〉 G) and rs1053023 (A 〉 G) polymorphisms in STAT3 using real-time PCR high resolution melting method (HRM). Results Our results revealed substantial associations between GG genotype and G allele of rs1053023 with enhanced risk of SLE (OR for GG genotype= 3.13; 95%CI [1.61–6.1], OR for G allele = 2.22; 95%CI [1.51–3.25] ). However, no important correlations have been found between rs1053005 polymorphism and SLE susceptibility in this population ( p 〉 0.05). Moreover, stratification analysis showed that these polymorphisms are correlated with parameters indicating disease activity and more severe course of the disease. These factors include some laboratory test results and clinical manifestations such as renal involvements. Conclusion The current study suggests a significant association between STAT3 polymorphisms and augmented risk of SLE, clinical symptoms, disease activity, and severity.
    Type of Medium: Online Resource
    ISSN: 0961-2033 , 1477-0962
    URL: Article
    DOI: 10.1177/09612033221076739
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2008035-9
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  • 8
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    Concerns and hopes about outsourcing decisions regarding health information management services at two teaching hospitals in Semnan, Iran
    SAGE Publications ; 2016
    In:  Health Information Management Journal Vol. 45, No. 1 ( 2016-04), p. 36-44
    Details
    In: Health Information Management Journal, SAGE Publications, Vol. 45, No. 1 ( 2016-04), p. 36-44
    Abstract: Changes in health programs in Iran have led to an increase in administrative costs. One cost-saving option available to hospital administrators is to outsource administrative services. Objective: This study aimed to explore the attitudes of hospital staff towards outsourcing health information management services in advance of a decision being taken, to assist healthcare organisations to assess the potential benefits and challenges of outsourcing such services. Method: Six hundred and four clinical and allied health employees in two hospitals in Iran, who had had prior experience with outsourcing hospital services, responded to a survey designed to measure staff attitudes towards outsourcing health information management services, based on their perceptions of potential costs and benefits for the organisation and their own employment prospects. A 16-item attitude scale, developed by the researchers, was used in the study and demographic data were also collected. Results: Summary statistics showed that approximately one third of the sample (34.53%) had a negative view of outsourcing, one third (35.16%) had a positive view, and 30.31% were neutral. An exploratory factor analysis of items on the attitude scale identified three underlying constructs, labelled: data security and management; workplace environment; and staff and customer satisfaction. One item (concern about the impact of outsourcing on staffing levels) did not load on any of the factors. A separate analysis of this single item showed a significant relationship between the sex of participants and their views on the impact of outsourcing on the number of hospital staff employed (p 〈 0.05). Conclusion: While results of this study indicated that staff in hospitals surveyed held both positive and negative views of outsourcing, a large number of staff in these hospitals (a third of the total sample) had reservations about the skills of outside providers to securely manage hospital data, and did not consider that outsourcing health information management services would be positive for the organisation, their working environment or for staff and patient satisfaction. These findings have important implications for healthcare organisations planning to outsource health information services. Further research that focuses on communication skills of senior managers and their ability to provide team leadership is needed, as is research into the impact of geographical location and current market forces that impact on outsourcing tasks.
    Type of Medium: Online Resource
    ISSN: 1833-3583 , 1833-3575
    URL: Article
    DOI: 10.1177/1833358316639455
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
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  • 9
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    Transobturator tape and mini-sling methods in stress urinary incontinence: Results of a randomized clinical trial
    SAGE Publications ; 2019
    In:  Urologia Journal Vol. 86, No. 3 ( 2019-08), p. 152-155
    Details
    In: Urologia Journal, SAGE Publications, Vol. 86, No. 3 ( 2019-08), p. 152-155
    Abstract: Stress urinary incontinence is one of the most common types of incontinence in premenopausal women, accounting for almost 50% of such cases. Mid-urethral slings are currently the most widely used surgical method for stress urinary incontinence. This study aimed at comparing the efficacy, complications, urodynamic changes and the sexual function status between mini-sling surgery and transobturator tape to help us select the best method in such patients. Method: In this randomized controlled trial, 80 cases were studied and randomly assigned to either the mini-sling or transobturator tape group (n = 40). A full medical history was taken and the Q.tip and cough tests were performed for each patient to record their urinary incontinence and hypermobility. Abdominal and pelvic ultrasound study was requested by specifying PVR and urodynamic testing. The International Consultation on Incontinence Modular Questionnaire-6 was filled by the patients and the Female Sexual Functioning Index questionnaire by the physician. The patients were followed-up 8 weeks after discharge by urodynamic tests, ultrasound study, and the International Consultation on Incontinence Modular Questionnaire test. Results: The mean age, body mass index, and parity were not significantly different between the two groups. The mean surgical time, amount of bleeding, hospitalization period, and pain index were significantly less in the mini-sling group. The International Consultation on Incontinence Modular Questionnaire and Female Sexual Functioning Index indices before and after surgery showed no significant difference between the two groups. The difference in urodynamic test parameters was also insignificant. Conclusion: In the mini-sling method which is a less invasive method compared to transobturator tape, the intraoperative bleeding, surgical time, hospitalization period, pain, and surgical complications were far less while its efficacy was similar to transobturator tape; therefore, it is recommended in treating stress urinary incontinence among women.
    Type of Medium: Online Resource
    ISSN: 0391-5603 , 1724-6075
    URL: Article
    DOI: 10.1177/0391560319845255
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2557852-2
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  • 10
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    A general iterative approach for solving the general constrained linear matrix equations system
    SAGE Publications ; 2016
    In:  Transactions of the Institute of Measurement and Control Vol. 38, No. 7 ( 2016-07), p. 805-818
    Details
    In: Transactions of the Institute of Measurement and Control, SAGE Publications, Vol. 38, No. 7 ( 2016-07), p. 805-818
    Abstract: Much of the research which has been done on special kinds of matrix equations has almost the same structure. In this paper, an iterative approach is proposed which is more general and includes all such matrix equations. This approach is based on the global least squares (GL-LSQR) method. To do so, a linear matrix operator, its adjoint and a proper inner product are defined. Then we demonstrate how to employ the new approach for solving the general linear matrix equations system. When the matrix equations are consistent, a least-norm solution can be obtained. Moreover, the optimal approximate solution to a given group of matrices can be derived. Also, some theoretical properties and the error analysis of the new method are discussed. Finally, some numerical experiments are given to compare the new iterative method with some existent methods in terms of their numerical results and illustrate the efficiency of the new method.
    Type of Medium: Online Resource
    ISSN: 0142-3312 , 1477-0369
    URL: Article
    DOI: 10.1177/0142331215581640
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2025882-3
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