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  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 2021
    In:  Trauma Vol. 23, No. 1 ( 2021-01), p. 55-63
    In: Trauma, SAGE Publications, Vol. 23, No. 1 ( 2021-01), p. 55-63
    Abstract: Identify physical findings in children with abdominal trauma to inform prehospital providers regarding appropriate hospital destinations. Methods This is a secondary analysis of the Pediatric Emergency Care Applied Research Network Abdominal Trauma Public Use Dataset. Children involved in motor vehicle collisions; struck by motor vehicles at 〉 20 mph; involved in all-terrain vehicle, motorcycle, or scooter accidents; or who fell from 〉 10 ft ( n = 5575) were included. Stepwise multivariable multinomial logistic regression was used to compare clinical findings at presentation between children with no intra-abdominal injury, intra-abdominal injury without intervention, and intra-abdominal injury with intervention (laparoscopy/laparotomy, embolization, red blood cell transfusion, or admission 〉 48 h on intravenous fluids). Results Compared to children with no intra-abdominal injury, children with intra-abdominal injury (with and without intervention) were more likely to have evidence of abdominal wall trauma, abdominal tenderness, peritoneal irritation, decreased breath sounds, distracting painful injury, and evidence of thoracic trauma. Children with intra-abdominal injury requiring intervention were more likely to have evidence of abdominal wall trauma (OR 3.32, 95% CI 2.03–5.44) and be intubated (OR 4.93, 95% CI 3.17–7.65) when compared to children with intra-abdominal injury without intervention. Conclusions The findings of abdominal tenderness, peritoneal irritation, decreased breath sounds, distracting painful injury, and thoracic trauma may be used to identify children who warrant evaluation at any trauma center because of increased risk of intra-abdominal injury, whereas intubation and evidence of abdominal wall trauma help identify children with intra-abdominal injury in need of transport to a pediatric trauma center due to risk of undergoing intervention.
    Type of Medium: Online Resource
    ISSN: 1460-4086 , 1477-0350
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2010984-2
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 1987
    In:  NASSP Bulletin Vol. 71, No. 502 ( 1987-11), p. 77-82
    In: NASSP Bulletin, SAGE Publications, Vol. 71, No. 502 ( 1987-11), p. 77-82
    Abstract: Here's how one school district has attempted to expand the instructional leadership role in its secondary schools through the selection and training of a group of department coordina tors. Since no such position had previously existed, it was an opportunity to define and develop this new role based on the research on instructional leadership and school culture.
    Type of Medium: Online Resource
    ISSN: 0192-6365 , 1930-1405
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1987
    detail.hit.zdb_id: 2067752-2
    SSG: 5,3
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 1995
    In:  Journal of Business and Technical Communication Vol. 9, No. 1 ( 1995-01), p. 5-41
    In: Journal of Business and Technical Communication, SAGE Publications, Vol. 9, No. 1 ( 1995-01), p. 5-41
    Abstract: This article explores the relationship between current theoretical definitions of risk communication, the unique national role that EPA plays in defining health and environmental risks, and possible explanations for EPA's inability to persuade the city of Aspen, Colorado, to accept its plan for a massive cleanup of toxic lead mine wastes. Many explanations for the reversal of EPA's cleanup plan at Aspen could be advanced, but we concentrate on the definition of risk communication upon which EPA's internal risk communication guidelines are based—guidelines that its field representatives are invited to follow. In particular, we now explore ownership messages conveyed through metacommunication conflict with EPA's risk communication guidelines.
    Type of Medium: Online Resource
    ISSN: 1050-6519 , 1552-4574
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1995
    detail.hit.zdb_id: 2059529-3
    detail.hit.zdb_id: 1218989-3
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2017
    In:  The American Surgeon Vol. 83, No. 5 ( 2017-05), p. 465-469
    In: The American Surgeon, SAGE Publications, Vol. 83, No. 5 ( 2017-05), p. 465-469
    Abstract: To describe the reasons and additional radiation for CT scans repeated after transfer to a trauma center. Retrospective study of patients transferred to a trauma center. Patients had repeat CT if a CTof the same region was repeated at the trauma center's emergency department. Indications for repeat CT scanning were abstracted. Radiation dosage was calculated in millisieverts. A total of 370 had CT scans and were transferred. Mean age was 39.1 ± 28.0 years. Seventy-four [20.0%, 95% confidence interval (CI) 16.0–24.4%] had 103 CTs repeated. Adults (64/254, 25.2%) were more likely than children (10/116, 8.6%) to undergo repeat CT (difference 16.6%, 95% CI 9.2–24.0%). Types of CTs repeated included: head 48 (47%), face 6 (6%), cervical spine/neck 21 (20%), thoracolumbar spine 4 (4%), chest 4 (4%), and abdominal/pelvic 20 (19%). Reasons for repeat CT were outside CT unavailable 31 (42%), insufficient image quality/additional details needed 15 (20%), disease progression 16 (22%), unknown 10 (14%), and consult request unknown reason 2 (3%). Median dose for the repeat CT scans was 4.19 mSv (interquartile range 1.98, 6.28) and was 4.79 mSv (interquartile range 2.47, 8.22) when the CTs were unavailable. Effective dose of the repeat scans was greater than 10 mSv in 13 (3.5%) pat ients. Patients transferred to a trauma center often undergo repeat CT. The most common reason for repeated imaging was failure to transport original CT scans with the patient or images that were unable to be viewed. Trauma centers should work with their catchment areas to establish systems that ensure transfer of all radiographic imaging.
    Type of Medium: Online Resource
    ISSN: 0003-1348 , 1555-9823
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
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  • 5
    In: Journal of Cerebral Blood Flow & Metabolism, SAGE Publications, Vol. 35, No. 3 ( 2015-03), p. 359-362
    Abstract: Vascular abnormalities are a key feature of Alzheimer's disease (AD). Imaging of cerebral vascular reactivity (CVR) is a powerful tool to investigate vascular health in clinical populations although the cause of reduced CVR in AD patients is not fully understood. We investigated the specific role of tau pathology in CVR derangement in AD using the rTg4510 mouse model. We observed an increase in CVR in cortical regions with tau pathology. These data suggest that tau pathology alone does not produce the clinically observed decreases in CVR and implicates amyloid pathology as the dominant etiology of impaired CVR in AD patients.
    Type of Medium: Online Resource
    ISSN: 0271-678X , 1559-7016
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2039456-1
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  • 6
    Online Resource
    Online Resource
    SAGE Publications ; 1991
    In:  Clinical Electroencephalography Vol. 22, No. 4 ( 1991-10), p. 211-216
    In: Clinical Electroencephalography, SAGE Publications, Vol. 22, No. 4 ( 1991-10), p. 211-216
    Type of Medium: Online Resource
    ISSN: 0009-9155
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1991
    detail.hit.zdb_id: 2647038-X
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  • 7
    In: Foot & Ankle International, SAGE Publications, Vol. 40, No. 9 ( 2019-09), p. 1043-1051
    Abstract: The aim of this study was to define the rate of new persistent opioid use and risk factors for persistent opioid use after operative and nonoperative treatment of ankle fractures. Methods: Using a nationwide insurance claims database, Clinformatics DataMart Database, we identified opioid-naïve patients who underwent surgical treatment of unstable ankle fracture patterns between January 2009 and June 2016. Patients who underwent closed treatment of a distal fibula fracture served as a comparative group. We evaluated peritreatment and posttreatment opioid prescription fills. The primary outcome, new persistent opioid use, was defined as opioid prescription fulfillment between 91 and 180 days after the procedure. Logistic regression was used to evaluate the effect of patient factors, and the differences of the effect were tested using Wald statistics. The adjusted persistent use rates were calculated. A total of 13 088 patients underwent treatment of an ankle fracture and filled a peritreatment opioid prescription. Results: When compared with closed treatment of a distal fibula fracture, only 2 surgical treatment subtypes demonstrated significantly increased rates of persistent use compared with the closed treatment group: open treatment of bimalleolar ankle fracture (adjusted odds ratio [aOR], 1.32; 95% CI, 1.10-1.58; P = .002) and open treatment of trimalleolar ankle fracture with fixation of posterior lip (aOR, 1.47; 95% CI, 1.04-2.07; P = .027). Rates were significantly increased (aOR, 1.56; 95% CI, 1.34-1.82; P 〈 .001) among patients who received a total peritreatment opioid dose that was in the top 25th percentile of total oral morphine equivalents. Factors independently associated with new persistent opioid use included mental health disorders, comorbid conditions, tobacco use, and female sex. Conclusion: All ankle fracture treatment groups demonstrated high rates of new persistent opioid use, and persistent use was not directly linked to injury severity. Instead, we identified patient factors that demonstrated increased risk of persistent opioid use. Limiting the peritreatment opioid dose was the largest modifiable risk factor related to new persistent opioid use in this privately insured cohort. Level of Evidence: Level III, retrospective cohort study.
    Type of Medium: Online Resource
    ISSN: 1071-1007 , 1944-7876
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2129503-7
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  • 8
    Online Resource
    Online Resource
    SAGE Publications ; 1991
    In:  The American Journal of Sports Medicine Vol. 19, No. 6 ( 1991-11), p. 596-600
    In: The American Journal of Sports Medicine, SAGE Publications, Vol. 19, No. 6 ( 1991-11), p. 596-600
    Abstract: A long-term retrospective study (minimum 5 years) was done looking at three groups of anterior cruciate defi cient knee patients using both subjective and objective anterior cruciate tests. Twenty-seven chronic anterior cruciate ligament deficient knees reconstructed with the middle third of the patellar tendon and 28 chronic anterior cruciate ligament deficient knees reconstructed with the semitendinosus tendon were included in this consecutive group of patients and were felt to be directly comparable. It was found that the chronic an terior cruciate ligament deficient group reconstructed with the semitendinosus tendon had 4 excellent, 10 good, 7 poor, and 7 failures with an objective score averaging 4.5 of a possible 12, while the comparable group reconstructed with the middle third of the patellar tendon had 16 excellent, 7 good, 3 poor, and only 1 failure with a score of 10 of a possible 12 (P 〈 0.0032). For completeness sake, 20 anterior cruciate deficient knees from this group of consecutive patients that were reconstructed acutely with the semitendinosus tendon were also examined. This group had 8 excellent results, 9 good, 3 poor, and no failures with a score of 9.8 (P 〈 0.03 compared to the other group using the semiten dinosus tendon). This comparison between the two groups where the semitendinosus tendon was used in the anterior cruciate ligament reconstruction was made only to show the difference between studies dealing with knee reconstructions. There may be a significant difference between a study dealing with acutely recon structed knees versus one focusing on chronically re constructed knees, most likely because of both patient selection and time between injury and reconstruction. Subjectively, the activity forms gave postreconstruc tion activities of 112 of 200 for the chronically recon structed group using semitendinosus tendon, 115 for the chronically reconstructed group using the middle third of the patellar tendon, and 150 in the acutely reconstructed group using the semitendinosus tendon. The subjects rated their knee 6.2 (chronically recon structed with semitendinosus), 6.4 (chronically recon structed with middle third patellar tendon), and 7.9 (acutely reconstructed with semitendinosus) on a scale of 0 to 10. This paper will point out the superiority of using the middle third of the patellar tendon over the use of the semitendinosus tendon in chronically unstable knees. The semitendinosus tendon should not be used even with extraarticular augmentations. The data for the semitendinosus tendon in acute anterior cruciate liga ment reconstruction is included to show how different two groups of patients can be based on the time of reconstruction from the date of injury.
    Type of Medium: Online Resource
    ISSN: 0363-5465 , 1552-3365
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1991
    detail.hit.zdb_id: 2063945-4
    SSG: 31
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  • 9
    Online Resource
    Online Resource
    SAGE Publications ; 2010
    In:  Clinical Medicine. Gastroenterology Vol. 3 ( 2010-01), p. CGast.S4469-
    In: Clinical Medicine. Gastroenterology, SAGE Publications, Vol. 3 ( 2010-01), p. CGast.S4469-
    Abstract: The incidence of microscopic colitis (MC) is increasing, but its etiology remains unknown. Case reports and limited controlled data suggest that commonly prescribed drugs may be triggers. The aim of this study was to evaluate the prevalence of selected medication use [Proton pump inhibitors (PPIs), HMG-CoA reductase inhibitors (statins), and Selective serotonin reuptake inhibitors (SSRIs)] in patients with MC compared to ‘random controls’ and ‘diarrhea controls.' Methods All patients were selected from primary care practices of a university health system during 2002 to 2007. Patients with biopsy proven lymphocytic or collagenous colitis were identified as cases. Diarrhea controls consisted of a 10:1 random sample of patients with chronic diarrhea and normal colon biopsies. Ten random controls were matched to each case on sex and index date (date of biopsy proven diagnosis). Drugs prescribed within the year prior to the index date were collected from the electronic medical record system. Results 26 cases (median age 68.9 yrs), 259 random, and 259 diarrhea controls were identified. The adjusted ORs for PPI, SSRI, and statin prescription within 12 months of diagnosis of MC between cases and diarrhea controls were 0.28 (0.07-1.07), 0.87 (0.28-2.64), 1.12 (0.34-3.71) respectively. Use of PPI and statins was less common in MC patients than in random controls ( P 〈 0.05 for both comparisons). Conclusions While prior data suggest that PPIs, statins, and SSRIs may be etiologically related to MC, our study found no increased association with these drugs.
    Type of Medium: Online Resource
    ISSN: 1178-119X
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2010
    detail.hit.zdb_id: 2435212-3
    detail.hit.zdb_id: 3011635-1
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