In:
Clinical and Applied Thrombosis/Hemostasis, SAGE Publications, Vol. 21, No. 3 ( 2015-04), p. 241-245
Kurzfassung:
There is no information about a possible association of red blood cell distribution width (RDW) with cryptogenic stroke (CS). We aimed to analyze the association of RDW with CS. Patients and Methods: One hundred and sixty-three patients with CS were included along with 186 healthy controls. Fibrinogen, leukocytes, hemoglobin, and erythrocyte indices were evaluated. Results: Patients showed higher RDW, leukocyte count, and body mass index (BMI) than controls ( P 〈 .05). No differences were observed in the erythrocyte indices or in glucose, cholesterol, and triglycerides levels ( P 〉 .05). When patients with anemia were excluded from the study (6 controls and 5 cases), the differences between cases and controls persisted ( P = .005). Multivariate logistic regression revealed that, after adjusting for potential confounders (anemia, age 〉 40 years, gender, and fibrinogen 〉 382 mg/dL, total cholesterol 〉 240 mg/dL, and BMI 〉 28.7 kg/m 2 ), RDW 〉 14% was the only parameter that independently increased the risk of CS. Conclusion: The RDW 〉 14% increased the risk of CS by 2.5-fold, irrespectively of anemia, inflammation, and lipidic profile.
Materialart:
Online-Ressource
ISSN:
1076-0296
,
1938-2723
DOI:
10.1177/1076029614547262
Sprache:
Englisch
Verlag:
SAGE Publications
Publikationsdatum:
2015
ZDB Id:
2230591-9
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