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  • 1
    In: Cephalalgia, SAGE Publications, Vol. 29, No. 6 ( 2009-06), p. 662-669
    Abstract: The objective of this study was to evaluate whether the quality of sleep and the degree of fatigue and daytime sleepiness are related to migraine. We investigated 489 subjects comprising 97 patients with eight or more, 77 patients with five to seven and 196 patients with one to four migraine days per month, and 119 migraine-free controls with fewer than six headache days per year. The patients were recruited via articles in newspapers not stressing the subject of the study. All participants underwent a semistructured interview and completed the Pittsburgh Sleep Quality Index (PSQI), the Fatigue Severity Scale (FSS), the Epworth Sleepiness Scale (ESS) and the Self-rating Depression Scale and the Self-rating Anxiety Scale. For statistical analysis we used two way MANOVAs, post hoc univariate two-way ANOVAs and Hochberg's GT2 tests as well as three-way mixed design ANOVAs. The PSQI total score was highest in patients with frequent migraine (5.9 ± 4.3) and lowest in controls (4.3 ± 2.5, P = 0.04). Four subscores of the PSQI showed similar statistically significant differences. The FSS and ESS scores did not differ in the four study groups. Analysing depression and anxiety revealed a significant impact on PSQI, FSS and ESS, but did not demonstrate interactions with migraine, thus suggesting that the impact of migraine is similar in patients without and with psychiatric comorbidity. In conclusion, the quality of sleep is decreased in patients with migraine, whereas fatigue and daytime sleepiness do not differ from healthy controls. The decreased quality of sleep in migraineurs is also a consequence of migraine itself and cannot be explained exclusively by comorbidity with depression or anxiety.
    Type of Medium: Online Resource
    ISSN: 0333-1024 , 1468-2982
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2009
    detail.hit.zdb_id: 2019999-5
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 2014
    In:  Global Spine Journal Vol. 4, No. 1_suppl ( 2014-05), p. s-0034-1376540-s-0034-1376540
    In: Global Spine Journal, SAGE Publications, Vol. 4, No. 1_suppl ( 2014-05), p. s-0034-1376540-s-0034-1376540
    Abstract: Extreme lateral interbody fusion (ELIF) is a novel technique for anterior spinal fixation and indirect decompression of neural elements. Materials and Methods Retrospective analysis of 145 ELIFs in 90 patients. Cages measuring 8 to 14 mm in height were used. Intervertebral disc height, foraminal height, cage position, and lumbar lordosis were determined on preoperative, postoperative, and the latest follow-up studies. Clinical outcomes were evaluated by Oswestry disability index (ODI) and visual analog scale (VAS). Results At the time of last follow-up (17.7 ± 1.1 months), two factors determined restoration of foraminal height: First, the amount of oversizing the graft (implant height-preoperative disc height) showed a significant positive correlation with increase of foraminal height (Pearson correlation coefficient 0.691, p 〈 0.001). Implantation of cages 6 to 9 mm higher than the preoperative disc resulted in 3.1 ± 0.3 mm foraminal height increase. Thus, cages oversized by 6 to 9 mm yielded in significantly greater restoration of foraminal height compared with grafts that were oversized by 0 to 3 mm ( p 〈 0.01) or 3 to 6 mm ( p 〈 0.05). The second determinant of foraminal height restoration was the footprint of the intervertebral spacer. Approximately one half of our patients received 18 mm spacers and the other 22 mm grafts. Eighteen mm spacers allowed for a 2.1 mm increase of foraminal height while 22 mm spacers lead to an increase by 4.0 mm on postoperative radiographs ( p 〈 0.001). Interestingly, neither cage position nor posterior instrumentation had statistically significant influence on restoration of foraminal height. ELIF interbody grafts provided adequate anterior column support with 1.0 ± 0.1 mm subsidence on last follow-up imaging compared with immediate postoperative studies. Subsidence was significantly greater with intervertebral cages that were oversized by 0 to 3 mm (1.7 ± 0.5 mm) compared with cages oversized by 6 to 9 mm (0.8 ± 0.2 mm, p 〈 0.05). One-third of patients received lordotic spacers. Both, lordotic and nonlordotic cages allowed for increased lumbar lordosis on postoperative imaging (6.0 and 4.7 degrees, respectively). Clinical evaluation revealed a mean ODI, VAS back, buttock, and leg pain improvements of 21.1%, 3.7, 3.6, and 3.7 points, respectively. Conclusion In ELIF, cage width and height but not cage position determine restoration of foraminal height. Thus, optimum foraminal height restoration is achieved by using 22 mm wide cages oversized by 6 to 9 mm in height. Disclosure of Interest None declared
    Type of Medium: Online Resource
    ISSN: 2192-5682 , 2192-5690
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2648287-3
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2014
    In:  Global Spine Journal Vol. 4, No. 1_suppl ( 2014-05), p. s-0034-1376721-s-0034-1376721
    In: Global Spine Journal, SAGE Publications, Vol. 4, No. 1_suppl ( 2014-05), p. s-0034-1376721-s-0034-1376721
    Abstract: Radiculopathy caused by foraminal nerve root compression is a common pathology of the lumbar spine. Surgical decompression through conventional open foraminotomy is the treatment of choice when surgery indicated. Minimally invasive tubular foraminotomy through a contralateral approach is a potentially effective treatment approach. The aim of this retrospective cohort study was to evaluate the efficacy and benefits of this approach for treatment of radiculopathy. Materials and Methods Patients with unilateral lower extremity radiculopathy, who underwent minimally invasive lumbar foraminotomy through tubular retractors via a contralateral approach between 2010 and 2012 were included. Oswestry disability index (ODI) and the visual analogue scale (VAS) for back, and leg pain were evaluated preoperatively, postoperatively, and at the latest follow-up. Functional outcome was evaluated using MacNab's criteria. Results For the total of 32 patients, postoperatively there was significant improvement in the ODI ( p = 0.006), VAS back pain ( p 〈 0.0001), and VAS leg pain on the pathology and the approach side ( p = 0.004, p = 0.021, respectively). At follow-up of 12.3 ± 1.7 months, there was also significant improvement in the ODI ( p 〈 0.0001), VAS back pain ( p = 0.001), and VAS leg pain on the pathology and the approach side ( p 〈 0.0001, p = 0.001, respectively). The functional outcome was excellent and good in 95.2%. One patient required fusion (3.1%). Conclusion A minimally invasive, facet-sparing contralateral approach is an effective technique for treatment of radiculopathy due to foraminal compression. It also allows for decompression of lumbar spinal stenosis and bilateral lateral recess decompression without the need for a fusion. Disclosure of Interest None declared
    Type of Medium: Online Resource
    ISSN: 2192-5682 , 2192-5690
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2648287-3
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2007
    In:  Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering Vol. 221, No. 4 ( 2007-04-01), p. 535-552
    In: Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering, SAGE Publications, Vol. 221, No. 4 ( 2007-04-01), p. 535-552
    Abstract: With the increased emphasis on both reliability and multi-functionality in the aerospace industry, active materials are fast becoming an enabling technology capturing the attention of an increasing number of engineers and scientists worldwide. This article reviews the class of active materials known as shape memory alloys (SMAs), especially as used in aerospace applications. To begin, a general overview of SMAs is provided. Their useful properties and engineering effects are described and the methods in which these may be utilized are discussed. A review of past and present aerospace applications is presented. The discussion addresses applications for both atmospheric earth flight as well as space flight. To complete the discussion, SMA design challenges and methodologies are addressed and the future of the field is examined.
    Type of Medium: Online Resource
    ISSN: 0954-4100 , 2041-3025
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2007
    detail.hit.zdb_id: 2032759-6
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  • 5
    Online Resource
    Online Resource
    SAGE Publications ; 2016
    In:  The Journal of Early Adolescence Vol. 36, No. 7 ( 2016-10), p. 909-931
    In: The Journal of Early Adolescence, SAGE Publications, Vol. 36, No. 7 ( 2016-10), p. 909-931
    Abstract: Youth aggression is a serious global issue, but research identifying personality traits associated with aggression has focused on adults. Little is known about whether similar associations exist during adolescence; even less is known about these associations across cultures. This study examined links between personality and physical aggression in U.S. and Chinese adolescents, and tested whether temper mediates these associations. U.S. ( N = 250) and Chinese ( N = 199) young adolescents ([Formula: see text] age = 13.43 years) completed self-reports describing personality, temper, and aggression. Path analyses demonstrated that temper significantly mediated associations from agreeableness and neuroticism to aggression in both samples. The mediating effect of temper was marginally stronger in the Chinese sample than in the U.S. sample, suggesting temper plays a more important role in youth aggression in China than in the United States. Findings highlight the universal role of affect in aggression and demonstrate the importance of cultural context in understanding links between personality and youth aggression.
    Type of Medium: Online Resource
    ISSN: 0272-4316 , 1552-5449
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2011499-0
    SSG: 5,2
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  • 6
    Online Resource
    Online Resource
    SAGE Publications ; 2014
    In:  Global Spine Journal Vol. 4, No. 1_suppl ( 2014-05), p. s-0034-1376718-s-0034-1376718
    In: Global Spine Journal, SAGE Publications, Vol. 4, No. 1_suppl ( 2014-05), p. s-0034-1376718-s-0034-1376718
    Abstract: StaXx XD is an expandable PEEK wafer implant that has been used in the treatment of lumbar degenerative disease. PEEK implants have been successfully used as interbody devices. There have been little studies evaluating the outcome of expandable PEEK devices. The aim of the current study was to determine the clinical effectiveness and radiographic outcome of expandable PEEK cages for interbody fusion. Materials and Methods This was a retrospective study of 49 consecutive patients who underwent lumbar interbody fusion with implantation of expandable PEEK cages in combination with posterior instrumentation using pedicle screw-rod constructs primarily for degenerative disorders. The patient's clinical outcomes were evaluated using the visual analog scale (VAS) and the Oswestry disability index (ODI). In addition, disc height, foraminal height, listhesis, local disc angle, lumbar lordosis, and graft subsidence were evaluated on pre-op, post-op, and on latest follow-op imaging. Results A total of 16 patients (32.6%) had undergone previous surgery at the index level. From pre-op to an average follow-up of 19.3 months, there was significant improvement in VAS back (6.42 vs. 3.11, p 〈 0.001), VAS buttock (4.66 vs. 1.97, p = 0.002), VAS leg (4.55 vs. 1.96, p 〈 0.001), and ODI (21.7 vs. 12.1, p 〈 0.001) scores. In addition, there was significant increase in the average disc height (6.49 vs. 8.18 mm, p = 0.037) and foraminal height (15.6 vs. 18.53, p = 0.0001), and there was a significant reduction in the amount of listhesis (5.13 vs. 3.15, p = 0.005). The increase in average local disc angle and overall lumbar lordosis was not significant. Subsidence of 0.66 mm (7.4%) was observed at the latest follow-up ( p = 0.35). Conclusion Our mid-term results indicate that in situ expandable PEEK spacers for lumbar interbody distraction can effectively and durably restore the disc height and foraminal height and are associated with significant improvement in the clinical outcome. Disclosure of Interest None declared
    Type of Medium: Online Resource
    ISSN: 2192-5682 , 2192-5690
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2648287-3
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  • 7
    Online Resource
    Online Resource
    SAGE Publications ; 2015
    In:  Psychological Science Vol. 26, No. 8 ( 2015-08), p. 1304-1315
    In: Psychological Science, SAGE Publications, Vol. 26, No. 8 ( 2015-08), p. 1304-1315
    Abstract: The present study examined whether adolescent friendships dissolve because of characteristics of friends, differences between friends, or both. Participants were 410 adolescents (201 boys, 209 girls; mean age = 13.20 years) who reported a total of 573 reciprocated friendships that originated in the seventh grade. We conducted discrete-time survival analyses, in which peer nominations and teacher ratings collected in Grade 7 predicted the occurrence and timing of friendship dissolution across Grades 8 to 12. Grade 7 individual characteristics were unrelated to friendship stability, but Grade 7 differences in sex, peer acceptance, physical aggression, and school competence predicted subsequent friendship dissolution. The findings suggest that compatibility is a function of similarity between friends rather than the presence or absence of a particular trait.
    Type of Medium: Online Resource
    ISSN: 0956-7976 , 1467-9280
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2022256-7
    SSG: 5,2
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  • 8
    In: Applied Spectroscopy, SAGE Publications, Vol. 48, No. 12 ( 1994-12), p. 1522-1528
    Abstract: This article describes the construction of a novel optically transparent thin-layer electrochemical (OTTLE) cell for IR and UV-Vis spectroelectrochemical experiments at variable temperature. The cell has a three-electrode set melt-sealed into a smooth polyethylene spacer which is sandwiched between two CaF 2 windows. The width of this spacer (0.18–0.20 mm) defines the thickness of the thin solution layer. The whole electrode assembly is housed in a thermostated Cu block of the OTTLE cell which fits into a double-walled nitrogen-bath cryostat. The experimental setup permits relatively fast electrolysis within the tested temperature range of 295 to 173 K under strictly anaerobic conditions and protection of light-sensitive compounds. Other important merits of the cell design include lack of leakage, facile cleaning, almost negligible variation of the preset temperature, and facile manipulation in the course of the experiments. The applicability of the variable-temperature IR/UV-Vis OTTLE cell is demonstrated by stabilization of a few electrogenerated carbonyl complexes of Mn(I) and Ru(II) with 3,5-di- tert. butyl-1,2-benzo(semi)quinone (DB(S)Q) and N, N′-diisopropyl-1,4-diaza-1,3-butadiene (iPr-DAB) ligands, respectively, at appropriately low temperatures.
    Type of Medium: Online Resource
    ISSN: 0003-7028 , 1943-3530
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1994
    detail.hit.zdb_id: 1474251-2
    SSG: 11
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  • 9
    Online Resource
    Online Resource
    SAGE Publications ; 2014
    In:  Global Spine Journal Vol. 4, No. 1_suppl ( 2014-05), p. s-0034-1376717-s-0034-1376717
    In: Global Spine Journal, SAGE Publications, Vol. 4, No. 1_suppl ( 2014-05), p. s-0034-1376717-s-0034-1376717
    Abstract: Surgical decompression is the intervention of choice for lumbar spinal stenosis (LSS) when nonoperative treatment has failed. Standard open laminectomy is an effective procedure. Minimally invasive laminectomy through tubular retractors is an alternative procedure. The aim of our cohort study was to evaluate the clinical and radiographic outcome of this procedure in LSS patients with or without preoperative spondylolisthesis. Materials and Methods Patients with LSS without spondylolisthesis and with stable spondylolisthesis who underwent MIS tubular laminectomy between 2004 and 2011 were included. Demographic, perioperative, and radiographic data were collected. Clinical outcome was evaluated by Oswestry disability index (ODI) and visual analog scale (VAS) scores, as well as by MacNab criteria. Results In a total of 110 patients, preoperative spondylolisthesis at the level of spinal stenosis was present in 52.5%. ODI and VAS pain scores at a mean follow-up of 28.8 months revealed a median improvement of 16% in ODI, 2.75 in VAS back, and 3 in VAS leg scores, compared with the preoperative baseline ( p 〈 0.0001). The reoperation rate requiring fusion was 3.5%. Patients with and without preoperative spondylolisthesis had no significant differences in their clinical outcome or the reoperation rate. Conclusion MIS laminectomy is an effective procedure for treatment of LSS. Reoperation rates for instability are lower than reported after open laminectomy. Functional improvement is similar in patients with and without preoperative spondylolisthesis. This procedure can be a viable alternative to open laminectomy. Routine fusion may not be indicated in all patients with LSS and spondylolisthesis. Disclosure of Interest None declared
    Type of Medium: Online Resource
    ISSN: 2192-5682 , 2192-5690
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2648287-3
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  • 10
    In: Clinical EEG and Neuroscience, SAGE Publications, Vol. 51, No. 4 ( 2020-07), p. 285-299
    Abstract: Posttraumatic stress disorder (PTSD) co-occurring with mild traumatic brain injury (mTBI) is common in veterans. Worse clinical outcome in those with PTSD has been associated with decreased serum neurosteroid levels. Furthermore, decreased cortical thickness has been associated with both PTSD and mTBI. However, it is not known whether decreased neurosteroids are associated with decreased cortical thickness in PTSD co-occurring with mTBI. This study included 141 individuals divided into the following groups: ( a) mTBI group (n = 32 [10 female, 22 male] veterans with a history of mTBI); ( b) PTSD + mTBI group (n = 41 [6 female, 35 male] veterans with current PTSD with a history of mTBI); and ( c) control group (n = 68 [35 female, 33 male] control participants), which were acquired through the Injury and Traumatic Stress (INTRuST) Clinical Consortium. Subjects underwent clinical assessment, magnetic resonance imaging at 3 T, and serum neurosteroid quantifications of allopregnanolone (ALLO) and pregnenolone (PREGN). Group differences in cortical thickness and associations between serum neurosteroid levels and cortical thickness were investigated. Cortical thickness was decreased in the PTSD + mTBI group compared with the other groups. In the PTSD + mTBI group, decreased cortical thickness was also associated with lower serum ALLO (right superior frontal cortex) and lower serum PREGN (left middle temporal and right orbitofrontal cortex). Cortical thickness in the middle temporal and orbitofrontal cortex was associated with PTSD symptom severity. There were no significant associations between neurosteroids and cortical thickness in the mTBI or control groups. Decreased cortical thickness in individuals with PTSD + mTBI is associated with decreased serum neurosteroid levels and greater PTSD symptom severity. Causality is unclear. However, future studies might investigate whether treatment with neurosteroids could counteract stress-induced neural atrophy in PTSD + mTBI by potentially preserving cortical thickness.
    Type of Medium: Online Resource
    ISSN: 1550-0594 , 2169-5202
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2647038-X
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