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  • 1
    Online Resource
    Online Resource
    Leg volume reduction during tiptoe movement is caused by venous ejection and calf muscle contraction
    SAGE Publications ; 2023
    In:  Phlebology: The Journal of Venous Disease Vol. 38, No. 6 ( 2023-07), p. 398-403
    Details
    In: Phlebology: The Journal of Venous Disease, SAGE Publications, Vol. 38, No. 6 ( 2023-07), p. 398-403
    Abstract: To clarify the cause of leg volume reduction during tiptoe movement in the standing position. Methods The right legs of 20 participants were assessed. The participants performed tiptoe movement in the supine position, and then stood up and performed the tiptoe movement and ankle dorsiflexion. Leg volume changes were recorded continuously using air plethysmography. Results Differences between leg volume changes due to tiptoe movement and the refilling volumes were not significantly different between the supine (59 mL) and standing (49 mL) positions, indicating that this amount of motion artifact was included in the downward trace recorded by tiptoe movement in the standing position. Conclusions Leg volume reduction during tiptoe movement in the standing position included a significant amount of motion artifacts. Therefore, it may be difficult to accurately measure the ejection volume using tiptoe movement in the standing position.
    Type of Medium: Online Resource
    ISSN: 0268-3555 , 1758-1125
    URL: Article
    DOI: 10.1177/02683555231179548
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 1463018-7
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  • 2
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    Post-treatment course of acute lipodermatosclerosis
    SAGE Publications ; 2023
    In:  Phlebology: The Journal of Venous Disease Vol. 38, No. 2 ( 2023-03), p. 73-79
    Details
    In: Phlebology: The Journal of Venous Disease, SAGE Publications, Vol. 38, No. 2 ( 2023-03), p. 73-79
    Abstract: We aimed to clarify whether acute lipodermatosclerosis (LDS) progress to chronic LDS without continued compression therapy. Methods Between April 2015 and November 2021, 30 patients with acute/subacute LDS, which was diagnosed clinically by presence of isolated, poorly demarcated, tender erythema, and induration limited to the lower leg(s), visited our clinic and were able to be followed up for longer than a year. We reviewed their treatment results and the post-treatment courses. Results In all cases, the symptoms in the acute phase subsided with compression bandages. After the discontinuation of compression therapy, 18 legs (56%) progressed to chronic LDS, and 14 legs (44%) did not. In the legs without progression, subcutaneous tissue in the affected leg was thicker compared with that in the contralateral leg (median 19.1 mm vs. 13.4 mm, p 〈 0.05) on the initial visit. In the legs with progression, the difference in subcutaneous tissue thickness between the affected and unaffected legs was not significant (10.0 mm vs. 7.6 mm). Conclusions Our findings suggest that in legs which later progress to chronic LDS, subcutaneous tissue contraction due to panniculitis is already present during the acute phase; therefore, long-term compression therapy is unlikely to improve the prognosis.
    Type of Medium: Online Resource
    ISSN: 0268-3555 , 1758-1125
    URL: Article
    DOI: 10.1177/02683555221147473
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
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  • 3
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    Online Resource
    Cell Magnetic Targeting System for Repair of Severe Chronic Osteochondral Defect in a Rabbit Model
    SAGE Publications ; 2016
    In:  Cell Transplantation Vol. 25, No. 6 ( 2016-06), p. 1073-1083
    Details
    In: Cell Transplantation, SAGE Publications, Vol. 25, No. 6 ( 2016-06), p. 1073-1083
    Abstract: The aim of this study was to investigate a cell delivery system for repair of severe chronic osteochondral defects using magnetically labeled mesenchymal stem cells (m-MSCs), with the aid of an external magnetic device, through the accumulation of a small number of m-MSCs into a desired area and to detect the suitable number of autologous m-MSCs needed for repair of the defect. Twenty-six male Japanese white rabbits aged 6 months were used. An osteochondral defect was created bilaterally at the weight-bearing surface of the medial femoral condyle of the rabbits' knees (3 mm diameter; 4 mm depth). At 4 weeks after creation of the defect, autogenic transplantation of the m-MSCs into the defect area was performed, followed by 10-min exposure to an external magnetic device, where animals were divided into four groups: high (1 × 10 6 m-MSCs), medium (2 × 10 5 m-MSCs), low (4 × 10 4 m-MSCs), and control (PBS injection). At 4 and 12 weeks posttransplantation of m-MSCs, repaired tissue was assessed histologically using the Fortier score with toluidine blue staining. Transplantation of a low number of m-MSCs was not enough to improve osteogenesis and chondrogenesis, but the medium and high groups improved repair of the chronic defect with chondrogenic tissues and showed histologically significantly better results than the control and low groups. The use of a magnetic targeting system for delivering m-MSCs has the potential to overcome the clinical hurdles for repair of the severe chronic osteochondral defect. Furthermore, this system is predicted to produce good clinical outcomes for humans, not only to repair osteochondral defects but also to repair a variety of damaged tissues.
    Type of Medium: Online Resource
    ISSN: 0963-6897 , 1555-3892
    URL: Article
    DOI: 10.3727/096368915X689613
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2020466-8
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  • 4
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    Online Resource
    Effects of leg compression and calf muscle contraction by active ankle motion on venous hemodynamics in sitting individuals
    SAGE Publications ; 2022
    In:  Phlebology: The Journal of Venous Disease Vol. 37, No. 5 ( 2022-06), p. 361-366
    Details
    In: Phlebology: The Journal of Venous Disease, SAGE Publications, Vol. 37, No. 5 ( 2022-06), p. 361-366
    Abstract: To clarify the effects of compression and active ankle motion on venous hemodynamics in healthy sitting individuals. Methods In the sitting position, 14 participants performed plantar flexion and dorsiflexion of the ankle for 3 s each without compression. Changes in the calf volume were recorded using air plethysmography. Subsequently, the process was repeated with the application of tubular elastic bandage (TEB), followed by anti-thrombotic stocking (ATS). Results The median interface pressure at the calf was 16 mmHg with TEB and 21 mmHg with ATS. Without compression ( N), the median venous volume was 76 mL. This was reduced to 58 mL with TEB and 56 mL with ATS ( p 〈 .01 vs. N for both). On the other hand, ejection volume by plantar flexion in N (27 mL) was not significantly changed with TEB (31 mL) or ATS (31 mL). Also, ejection volume by dorsiflexion in N (53 mL, p 〈 .001 vs. plantar flexion) was not significantly changed with TEB (53 mL, p 〈 .01 vs. plantar flexion) or ATS (41 mL, p 〈 .05 vs. plantar flexion). Conclusions The venous volume, which is defined as the change in enclosed calf volume from elevation to dependency, in the sitting position reduced similarly with TEB and ATS; however, the ejection volumes did not change significantly. Dorsiflexion exerted a larger ejection volume than plantar flexion in the sitting position.
    Type of Medium: Online Resource
    ISSN: 0268-3555 , 1758-1125
    URL: Article
    DOI: 10.1177/02683555221077741
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
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  • 5
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    Online Resource
    A New Method for Separating Configurational and Constitutional Chiralities Using Diffuse Reflectance Circular Dichroism (DRCD)
    SAGE Publications ; 2013
    In:  Applied Spectroscopy Vol. 67, No. 10 ( 2013-10), p. 1210-1213
    Details
    In: Applied Spectroscopy, SAGE Publications, Vol. 67, No. 10 ( 2013-10), p. 1210-1213
    Abstract: Solid-state chiral chemistry has attracted significant scientific interest because of its application in the chiral-selective production, chiral recognition, resolution, and detection of enantiomers of a chiral compound. Combining a novel diffuse reflectance circular dichroism (DRCD) technique with powder X-ray crystallographic analysis, we investigated the origin of chiral properties from the molecular and supramolecular chiralities and the possibility of separating independent CD signals from the superimposed CD signal resulting from different chiral origins.
    Type of Medium: Online Resource
    ISSN: 0003-7028 , 1943-3530
    URL: Article
    DOI: 10.1366/13-07087
    RVK:
    VA 2367
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 1474251-2
    SSG: 11
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  • 6
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    Online Resource
    Spectroscopic Characterization of Supramolecular Chiral Porphyrin Homoassociates at the Air–Water Interface
    SAGE Publications ; 2014
    In:  Applied Spectroscopy Vol. 68, No. 11 ( 2014-11), p. 1235-1240
    Details
    In: Applied Spectroscopy, SAGE Publications, Vol. 68, No. 11 ( 2014-11), p. 1235-1240
    Abstract: The water-soluble 4-sulfonatophenyl meso-substituted porphyrin (TPPS) dye exhibits a transformation to a chiral self-aggregate from the non-aggregated species (diprotonated H 4 TPPS 2– ) at low concentration (no more than 1 × 10 −5 M). Immobilization of supramolecular chiral porphyrin homoassociates was mediated by the electrostatic interaction between the anionic TPPS molecule and cationic surfactant monolayer at the air–water interface. With the immobilization, a reversible transformation from monomeric TPPS to J-aggregate ( M→J) could be changed into an irreversible ( M→J), which is desirable for stabilization of aggregation structure for a long period. The novel finding was achieved using a fine-tuned specialized solid-state circular dichroism (CD) spectrophotometer and derived analytical procedure to obtain artifact-free CD signals. To our knowledge, this is the first report achieving the chiral control of a homoassociate induced by a chiral surfactant at the air–water interface, indicating that the handedness of the formed homoassociate could be determined.
    Type of Medium: Online Resource
    ISSN: 0003-7028 , 1943-3530
    URL: Article
    DOI: 10.1366/13-07432
    RVK:
    VA 2367
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 1474251-2
    SSG: 11
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  • 7
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    Online Resource
    Role of Mesenchymal Stem Cells Densities When Injected as Suspension in Joints with Osteochondral Defects
    SAGE Publications ; 2019
    In:  CARTILAGE Vol. 10, No. 1 ( 2019-01), p. 61-69
    Details
    In: CARTILAGE, SAGE Publications, Vol. 10, No. 1 ( 2019-01), p. 61-69
    Abstract: The aim of this study was to evaluate an intraarticular injection of different doses of autologous mesenchymal stem cells (MSCs) for improving repair of midterm osteochondral defect. Design At 4 weeks postoperative marrow stimulation model bilaterally (3 mm diameter; 4 mm depth) in the medial femoral condyle, autologous MSCs were injected into knee joint. Twenty-four Japanese rabbits aged 6 months were divided randomly into 4 groups ( n = 6 per group): the control group and and MSC groups including 0.125, 1.25, and 6.25 million MSCs. Repaired tissue was assessed macroscopically and histologically at 4 and 12 weeks after intraarticular injection of MSCs. Results At 12 weeks, there was no repair tissue in the control group. The gross appearance of the 1.25 and 6.25 million MSC groups revealed complete repair of the defect with white to pink tissue at 12 weeks. An osteochondral repair was histologically significantly better in the 1.25 and 6.25 million MSC groups than in the control and 0.125 million MSC groups at 4 and 12 weeks, due to presence of hyaline-like tissue in the deep layer at 4 weeks, and at 12 weeks hyaline cartilage formation at the periphery and fibrous tissue containing some chondrocytes in the deep layer of the center of the defect. Subchondral bone was restructured in the 1.25 and 6.25 million MSC groups, although it did not resemble the normal bone. Conclusion An intraarticular injection of 1.25 or 6.25 million MSCs could promote the repair of subchondral bone, even in the case of midterm osteochondral defect.
    Type of Medium: Online Resource
    ISSN: 1947-6035 , 1947-6043
    URL: Article
    DOI: 10.1177/1947603517708333
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2515870-3
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  • 8
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    Online Resource
    No ochronosis was seen at internal thoracic artery with alkaptonuria
    SAGE Publications ; 2019
    In:  Asian Cardiovascular and Thoracic Annals Vol. 27, No. 6 ( 2019-07), p. 486-488
    Details
    In: Asian Cardiovascular and Thoracic Annals, SAGE Publications, Vol. 27, No. 6 ( 2019-07), p. 486-488
    Abstract: Alkaptonuria is a rare disorder of amino acid metabolism that causes premature large joint spine arthropathy and cardiac disease. We describe a case of aortic stenosis and coronary artery disease associated with ochronosis in a 76-year-old man who underwent aortic valve replacement and coronary artery bypass grafting. Although the ochronosis was extensive, no ochronosis was seen in the internal thoracic artery which used for coronary artery bypass grafting. Ochronosis with alkaptonuria is considered to accelerate the atherosclerotic process, so the internal thoracic artery may ensure a better long-term outcome. Long-term follow-up may allow better understanding of this rare condition.
    Type of Medium: Online Resource
    ISSN: 0218-4923 , 1816-5370
    URL: Article
    DOI: 10.1177/0218492318813791
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2044527-1
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  • 9
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    Online Resource
    Traumatic Dislocated Clavicle Fracture with the Oppression of Superior Vena Cava
    SAGE Publications ; 2006
    In:  Asian Cardiovascular and Thoracic Annals Vol. 14, No. 1 ( 2006-02), p. 85-85
    Details
    In: Asian Cardiovascular and Thoracic Annals, SAGE Publications, Vol. 14, No. 1 ( 2006-02), p. 85-85
    Type of Medium: Online Resource
    ISSN: 0218-4923 , 1816-5370
    URL: Article
    DOI: 10.1177/021849230601400122
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2006
    detail.hit.zdb_id: 2044527-1
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  • 10
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    Two-stage repair of DeBakey type IIIb aneurysm, using total arch replacement
    SAGE Publications ; 2020
    In:  Asian Cardiovascular and Thoracic Annals Vol. 28, No. 1 ( 2020-01), p. 7-14
    Details
    In: Asian Cardiovascular and Thoracic Annals, SAGE Publications, Vol. 28, No. 1 ( 2020-01), p. 7-14
    Abstract: Open repair for chronic DeBakey type IIIb dissecting aortic aneurysm is an invasive procedure involving open proximal anastomosis under hypothermic cardiac arrest, with significant morbidity in high-risk patients. We adopted a two-stage repair strategy using total arch replacement with the elephant trunk technique, which enables aortic crossclamping and avoids open proximal anastomosis at the second-stage graft replacement through a left thoracotomy. Methods From January 2008 to October 2018, we performed DeBakey type IIIb dissecting aortic aneurysm repair in 76 cases, and compared the results of two-stage repair (group 1, 25 cases) and single-stage repair using graft replacement with open proximal anastomosis through a left thoracotomy (group 2, 31 cases). Results In group 1, the elephant trunk technique was successful in all cases. The second intervention included endovascular repair (13 cases) and graft replacement through a left thoracotomy (7 cases). Five cases were followed up conservatively because the false lumen was thrombosed after the elephant trunk technique. Aorta-related adverse events were seen in 5 cases in group 1 (1 re-dissection, 1 rupture, 2 stent-graft-induced new entries, 1 stent-graft migration) and 6 in group 2 (1 additional thoracic endovascular aortic repair, 1 rupture, 4 acute type A aortic dissections). There were no statistical differences between the two groups regarding aorta-related adverse events and death. The postoperative course was acceptable in both groups. Conclusions Single-stage repair with open proximal anastomosis is an option in patients not at high risk for invasive surgery, while two-stage repair is recommended for high-risk patients.
    Type of Medium: Online Resource
    ISSN: 0218-4923 , 1816-5370
    URL: Article
    DOI: 10.1177/0218492319895377
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2044527-1
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