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  • SAGE Publications  (2)
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  • SAGE Publications  (2)
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  • 1
    Online Resource
    Online Resource
    Sinus Arrest After Administration of Intravenous Metoclopramide
    SAGE Publications ; 1995
    In:  Annals of Pharmacotherapy Vol. 29, No. 4 ( 1995-04), p. 381-383
    Details
    In: Annals of Pharmacotherapy, SAGE Publications, Vol. 29, No. 4 ( 1995-04), p. 381-383
    Abstract: Sinus arrest is a rare complication of metoclopramide administration. Case Description: A 51-year-old woman developed Guillain-Barre syndrome and severe dysautonomia. Metoclopramide was administered for the treatment of gastroparesis. Sinus arrest followed drug administration on several occasions and on rechallenge. Conclusions: After reviewing the literature and discussing possible etiologies for this unusual adverse drug reaction in this setting, we recommend that metoclopramide be used with caution in patients prone to develop bradyarrythmias, particularly those with dysautonomias and Guillain-Barre syndrome.
    Type of Medium: Online Resource
    ISSN: 1060-0280 , 1542-6270
    URL: Article
    DOI: 10.1177/106002809502900408
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1995
    detail.hit.zdb_id: 2053518-1
    SSG: 15,3
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  • 2
    Online Resource
    Online Resource
    Cerebrovascular Hemodynamic Inefficiency of Premature Ventricular Contractions
    SAGE Publications ; 1996
    In:  Angiology Vol. 47, No. 1 ( 1996-01), p. 51-56
    Details
    In: Angiology, SAGE Publications, Vol. 47, No. 1 ( 1996-01), p. 51-56
    Abstract: Transcranial Doppler (TCD) measurements of middle cerebral artery (MCA) blood flow velocities were recorded and synchronized with electrocardiographic (EKG) recordings in 52 EKG/TCD complexes in 4 patients. Thirty-seven normal sinus beats and 13 conductive and 2 nonconductive premature ventricular contractions (PVCs) were examined. Mean velocities averaged 45 ± 4 cm/sec for normal sinus rhythm (NSR) vs 26 ± 4 cm/sec in the PVC group (P = 0.007). Peak systolic velocities averaged 74 ± 6 cm/sec for the NSR and 45 ± 7 cm/sec in the PVC group (P = 0.016). The latency between the QRS complexes and corresponding TCD wave forms (QRS-SU) averaged 0.12 ± 0.03 sec in NSR and 0.17 ± 0.04 sec for the PVC group (P 〈 0.001). In addition, QRS-SU was inversely related to all velocities. PVCs appeared to be less hemodynamically efficient than NSR. The lower blood flow velocities and increased QRS-SU may result from lower stroke volume and delayed ventricular contraction associated with the aberrant QRS complex.
    Type of Medium: Online Resource
    ISSN: 0003-3197 , 1940-1574
    URL: Article
    DOI: 10.1177/000331979604700107
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1996
    detail.hit.zdb_id: 2065911-8
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