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  • SAGE Publications  (108)
  • 1
    Online Resource
    Online Resource
    Upregulation of ID2 Antagonizes Arsenic Trioxide-induced Antitumor Effects in Cancer Cells
    SAGE Publications ; 2014
    In:  Tumori Journal Vol. 100, No. 3 ( 2014-05), p. 352-357
    Details
    In: Tumori Journal, SAGE Publications, Vol. 100, No. 3 ( 2014-05), p. 352-357
    Type of Medium: Online Resource
    ISSN: 0300-8916 , 2038-2529
    URL: Article
    DOI: 10.1177/1578.17226
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 280962-X
    detail.hit.zdb_id: 2267832-3
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  • 2
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    Theoretical, numerical, and experimental study on synchronization of three motors coupled with a tensile spring in a nonlinear vibrating system
    SAGE Publications ; 2023
    In:  Journal of Vibration and Control Vol. 29, No. 1-2 ( 2023-01), p. 298-316
    Details
    In: Journal of Vibration and Control, SAGE Publications, Vol. 29, No. 1-2 ( 2023-01), p. 298-316
    Abstract: A synchronization mechanism for three motors coupled with a tensile spring in a nonlinear vibrating system is proposed to apply in drilling fluid shaker. The purpose of this paper is to investigate the synchronization mechanism of the system. Firstly, the dynamic equations of the system are established by using the Lagrange’s equation, and the steady-state solutions of the system are solved. Then, synchronous conditions and stability criteria of the system in a steady state are obtained. Next, the influences of various structure parameters on the synchronous state of the system are numerically discussed. Additionally, we use the Runge–Kutta algorithm to build an electromagnetic coupling model, and the synchronous behavior of the system is explored. Finally, an experimental strategy including the synchronous tests of the system is implemented to verify the correctness of theoretical analysis, numerical discussion, and simulation. It is concluded that the steady synchronous motion of three motors can be achieved by selecting an appropriate stiffness of the tensile spring. All these study results will provide a strong support for developing the design of large-scale vibration machinery with high efficiency and energy-saving in engineering.
    Type of Medium: Online Resource
    ISSN: 1077-5463 , 1741-2986
    URL: Article
    DOI: 10.1177/10775463211047125
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2070247-4
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  • 3
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    Online Resource
    Stem Cells from Human Exfoliated Deciduous teeth Promote Hair Regeneration in Mouse
    SAGE Publications ; 2021
    In:  Cell Transplantation Vol. 30 ( 2021-01-01), p. 096368972110429-
    Details
    In: Cell Transplantation, SAGE Publications, Vol. 30 ( 2021-01-01), p. 096368972110429-
    Abstract: Stem cells in different types may interact with each other to maintain homeostasis or growth and the interactions are complicated and extensive. There is increasing evidence that mesenchymal-epithelial interactions in early morphogenesis stages of both tooth and hair follicles show many similarities. In order to explore whether stem cells from one tissue could interact with cells from another tissue, a series of experiments were carried out. Here we successfully extracted and identified stem cells from human exfoliated deciduous teeth (SHED) of 8–12 years old kids, and then found that SHED could promote hair regeneration in a mouse model. In vitro, SHED shortened the hair regeneration cycle and promoted the proliferation and aggregation of dermal cells. In vivo, when SHED and skin cells of C57 mice were subcutaneously co-transplanted to nude mice, more hair was formed than skin cells without SHED. To further explore the molecular mechanism, epidermal and dermal cells were freshly extracted and co-cultured with SHED. Then several signaling molecules in hair follicle regeneration were detected and we found that the expression of Sonic Hedgehog (Shh) and Glioma-associated oncogene 1 (Gli1) was up-regulated. It seems that SHED may boost the prosperity of hairs by increase Shh/Gli1 pathway, which brings new perspectives in tissue engineering and damaged tissue repairing.
    Type of Medium: Online Resource
    ISSN: 0963-6897 , 1555-3892
    URL: Article
    DOI: 10.1177/09636897211042927
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2020466-8
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  • 4
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    Design, preparation and characterization of three-dimensional auxetic warp and weft backed weave fabrics based on origami tessellation structures
    SAGE Publications ; 2022
    In:  Textile Research Journal Vol. 92, No. 19-20 ( 2022-10), p. 3797-3807
    Details
    In: Textile Research Journal, SAGE Publications, Vol. 92, No. 19-20 ( 2022-10), p. 3797-3807
    Abstract: Materials with a negative Poisson’s ratio (NPR) are also called auxetic materials, which as a branch of mechanical metamaterials have drawn a great deal of attention in many areas. Origami tessellation structures (OTSs) exhibit an in-plane NPR; meanwhile, they may also show an out-of-plane NPR, which may be called three-dimensional (3D) auxetic structures. In the crease pattern of OTSs, there are folding lines in perpendicular directions. Contractions in the warp direction need warp backed weave structures. Herein, warp and weft backed weaves are used together and three OTS Jacquard fabrics are designed. From the physical map, we can see that the elastic warp yarns and elastic weft yarns can form floats in the warp and weft directions, and the flat fabrics can be folded in to 3D OTSs according to the crease patterns designed. The in-plane and out-of-plane Poisson’s ratios of OTSs have been predicted and, subsequently, compared with the experimental results. All OTS fabrics can show an in-plane NPR, two fabrics show out-of-plane NPRs and one shows an out-of-plane positive Poisson’s ratio. A parametric analysis about the interior angle has revealed the interplay between the geometrical parameters of OTSs and the Poisson’s ratio. In various design fields, elastic yarns combined with warp and weft backed weave textile technology can pave the way for realizing new crease pattern fabrics focused on 3D auxetic materials. Theoretical results can provide methodological guidance and technical support for the design and manufacture of OTS fabrics with optimum functional performance or desired aesthetics.
    Type of Medium: Online Resource
    ISSN: 0040-5175 , 1746-7748
    URL: Article
    DOI: 10.1177/00405175221094044
    RVK:
    ZS 0001
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2209596-2
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  • 5
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    Online Resource
    Continuous Low-Dose Apatinib Combined With WBRT Significantly Reduces Peritumoral Edema and Enhances the Efficacy of Symptomatic Multiple Brain Metastases in NSCLC
    SAGE Publications ; 2021
    In:  Technology in Cancer Research & Treatment Vol. 20 ( 2021-01-01), p. 153303382110119-
    Details
    In: Technology in Cancer Research & Treatment, SAGE Publications, Vol. 20 ( 2021-01-01), p. 153303382110119-
    Abstract: Symptomatic multiple brain metastases with peritumoral brain edema (PTBE) occur in non-small cell lung cancer patients (NSCLC) who are without driver mutations or are resistant to epidermal growth factor tyrosine kinase (EGFR-TKI) are often associated with an unfavorable prognosis. Whole brain radiation therapy (WBRT) which comes with many complications and unsatisfactory effects, is the only option for the treatment. Previous studies have shown that bevacizumab can reduce the volume of PTBE and improve efficiency of radiotherapy. This study evaluated the effects and safety of apatinib combined with WBRT in NSCLC patients with symptomatic multiple brain metastases and PTBE. Methods: We performed a retrospective review of 34 patients with symptomatic multiple brain metastases from NSCLC (number 〉 4, and at least 1 measurable brain metastasis lesion with cerebral edema). Intracranial objective response rate (IORR), peritumoral edema and intracranial tumor volumetric measurement, Karnofsky performance status (KPS) and adverse events (AEs) were evaluated. Median intracranial progression-free survival (mIPFS) and median overall survival (mOS) were also analyzed. Results: Thirteen cases received apatinib (125 mg or 250 mg, QD, oral) combined with WBRT and 21 cases received chemotherapy combined with WBRT were inclued. Apatinib combination group can better reduce the volume of intracranial tumors and PTBE and total steroid dosage used. It was associated with a better IORR (84.6% vs 47.6%, P = 0.067), longer mIPFS (6.97 vs 4.77months; P = 0.014). There was no significant difference in mOS(7.70 vs 6.67 months; P = 0.14) between the 2 groups. The most common adverse events of apatinib combination WBRT included grade 1/2 nausea (4/13), fatigue (3/13), hypertension (2/13) and white blood cell decrease (2/13). No grade 3/4 AEs were observed. Conclusion: Apatinib plus WBRT is well tolerated and may be a potential choice for relapsed or drug-resistant advanced NSCLC patients with symptomatic multiple brain metastases and PTBE.
    Type of Medium: Online Resource
    ISSN: 1533-0346 , 1533-0338
    URL: Article
    DOI: 10.1177/15330338211011968
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2146365-7
    detail.hit.zdb_id: 2220436-2
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  • 6
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    Prediction of oxygen distribution in the waste mass from an aeration well in bioreactor landfills
    SAGE Publications ; 2023
    In:  Waste Management & Research: The Journal for a Sustainable Circular Economy
    Details
    In: Waste Management & Research: The Journal for a Sustainable Circular Economy, SAGE Publications
    Abstract: The key to upgrade the efficiency of aerobic remediation of landfills is to determine the distribution characteristics of oxygen concentration during aerobic ventilation. This study discusses the distribution law of oxygen concentration with time and radial distance based on a single-well aeration test at an old landfill site. The transient analytical solution of the radial oxygen concentration distribution was deduced using the gas continuity equation and approximation of calculus and logarithmic functions. Oxygen concentration data from the field monitoring were compared with the results predicted by the analytical solution. The results indicated that the oxygen concentration initially increased and then decreased with prolonged aeration time. With an increase in radial distance, the oxygen concentration rapidly declined, followed by a gradual decrease. The influence radius of the aeration well increased slightly when the aeration pressure increased from 2 to 20 kPa. The field test data agreed with the analytical solution prediction results, preliminarily verifying the reliability of the oxygen concentration prediction model. Results from this study provide a basis of guidelines for the design, operation and maintenance management of a landfill aerobic restoration project.
    Type of Medium: Online Resource
    ISSN: 0734-242X , 1096-3669
    URL: Article
    DOI: 10.1177/0734242X231171039
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 1480483-9
    detail.hit.zdb_id: 46937-3
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  • 7
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    Effects of dual-task training on gait and motor ability in patients with Parkinson's disease: A systematic review and meta-analysis
    SAGE Publications ; 2023
    In:  Clinical Rehabilitation Vol. 37, No. 7 ( 2023-07), p. 942-953
    Details
    In: Clinical Rehabilitation, SAGE Publications, Vol. 37, No. 7 ( 2023-07), p. 942-953
    Abstract: Parkinson's disease is one of the most common neurodegenerative diseases in the world, which seriously damages motor and balance ability. Dual-task training is discussed as an appropriate intervention. The aim of this review was to synthesize the existing research findings on the efficacy of dual-task training for people with Parkinson's disease. Data resources A systematic search on PubMed, CENTRAL, Embase, Web of Science, and PEDro, randomized-controlled trials (RCTs) of dual-task training for individuals with Parkinson's disease. Methods Articles published until 1 November 2022 were included. Our search identified 7 RCTs with a total of 406 subjects. Review Manager 5.4 software was used for bias evaluation and to process the results of the outcome measures collected from the investigations. Results Dual-task training was associated with significant improvement in most motor and balance outcomes including gait velocity (standard mean difference (SMD) = 0.62; 95% CI, 0.37–0.87; I 2  = 31%; P = 0.21), cadence (SMD = 0.29; 95% CI, 0.05–0.53; I 2  = 0%; P = 0.71), timed-up-and-go test (mean difference (MD) = -2.38; 95% CI, −3.93 to −0.84; I 2  = 32%; P = 0.22) and mini-balance evaluation systems test (MD = 2.04; 95% CI, 1.05–3.03; I 2  = 0%; P = 0.92). Conclusion Evidence from meta-analyses suggests that dual-task training may improve motor and balance abilities in Parkinson's disease patients. Future research should focus on finding the most appropriate dual-task treatment model for patients with different degrees, in order to further improve the rehabilitation treatment of Parkinson's disease.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    URL: Article
    DOI: 10.1177/02692155221146085
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2028323-4
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  • 8
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    Successful Endoscopic Sclerotherapy Using Lauromacrogol Injection for Laryngopharyngeal Hemangioma
    SAGE Publications ; 2021
    In:  Ear, Nose & Throat Journal Vol. 100, No. 9 ( 2021-11), p. 662-666
    Details
    In: Ear, Nose & Throat Journal, SAGE Publications, Vol. 100, No. 9 ( 2021-11), p. 662-666
    Abstract: Objectives: This study aims to investigate the efficacy and safety of local lauromacrogol injection in the treatment of hypopharyngeal hemangioma. Methods: From Aug 2015 to May 2021, 13 consecutive patients suffering from hypopharyngeal hemangioma underwent local lauromacrogol injection assisted by endoscope in this prospective clinical series. All patients were followed up regularly and the therapeutic effects and complications were observed. Results: A total 13 of patients were enrolled, including 11 men and 2 women, with an average age of 48.5 years (range 25–76 years). The sizes of the hemangioma ranged from 0.5 × 1.0 cm to 3.5 × 3.5 cm. After 1 to 40 months of follow-up, 12 patients were cured and 1 was significantly effective after 1 to 4 (mean 1.8) injections. All patients suffered varying degrees of postoperative pain or foreign body sensation. 3 patients were significantly affected by local swelling of the injection site, 2 of which underwent prophylactic tracheostomy postoperatively and 1 patient returned to the ward with endotracheal intubation postoperatively. No complications such as mucosal ulceration, fever, and allergies occurred. Conclusions: Lauromacrogol injection is a safe and effective method to treat hypopharyngeal hemangioma.
    Type of Medium: Online Resource
    ISSN: 0145-5613 , 1942-7522
    URL: Article
    DOI: 10.1177/01455613211043690
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2067528-8
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  • 9
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    Reversible physical crosslinking strategy with optimal temperature for 3D bioprinting of human chondrocyte-laden gelatin methacryloyl bioink
    SAGE Publications ; 2018
    In:  Journal of Biomaterials Applications Vol. 33, No. 5 ( 2018-11), p. 609-618
    Details
    In: Journal of Biomaterials Applications, SAGE Publications, Vol. 33, No. 5 ( 2018-11), p. 609-618
    Abstract: Gelatin methacryloyl is a promising material in tissue engineering and has been widely studied in three-dimensional bioprinting. Although gelatin methacryloyl possesses excellent biocompatibility and tunable mechanical properties, its poor printability/processability has hindered its further applications. In this study, we report a reversible physical crosslinking strategy for precise deposition of human chondrocyte-laden gelatin methacryloyl bioink at low concentration without any sacrificial material by using extrusive three-dimensional bioprinting. The precise printing temperature was determined by the rheological properties of gelatin methacryloyl with temperature. Ten percent (w/v) gelatin methacryloyl was chosen as the printing formula due to highest biocompatibility in three-dimensional cell cultures in gelatin methacryloyl hydrogel disks. Primary human chondrocyte-laden 10% (w/v) gelatin methacryloyl was successfully printed without any construct deformation or collapse and was permanently crosslinked by ultraviolet light. The printed gelatin methacryloyl hydrogel constructs remained stable in long-term culture. Chondrocyte viability and proliferation that were printed under this optimal temperature were better than that of chondrocytes printed under lower temperatures and were similar to that of chondrocytes in the non-printed gelatin methacryloyl hydrogels. The results indicate that with this strategy, 10% (w/v) gelatin methacryloyl bioink presented excellent printability and printing resolution with high cell viability, which appears to be suitable for printing primary human chondrocytes in cartilage biofabrication and can be extensively applied in tissue engineering of other organs or in other biomedical fields.
    Type of Medium: Online Resource
    ISSN: 0885-3282 , 1530-8022
    URL: Article
    DOI: 10.1177/0885328218805864
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2072559-0
    SSG: 12
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  • 10
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    Investigation on NO reduction behavior within complex atmosphere during pilot ignition of low calorific gas
    SAGE Publications ; 2023
    In:  Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy Vol. 237, No. 5 ( 2023-08), p. 1053-1060
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy, SAGE Publications, Vol. 237, No. 5 ( 2023-08), p. 1053-1060
    Abstract: Low calorific gas (LCG) is largely produced in industries and agricultures, but its utilization is difficult due to the poor combustibility and high NO x emission. The pilot ignition combustion has the potential to improve LCG’s combustibility and also reduce NO production with combining air stage approach. However, the complex atmosphere created under pilot ignition condition could complicate the NO reduction (by CH 4 ) behavior and should be clarified. This paper is aimed at gain a deep insight on this issue by exploring the interaction between temperature and atmosphere, the individual role of α and CH 4 concentration (or its ratio to NO), and the influence of CO and CO 2 presence. The results show that with dropping α, the maximum NO reduction ratio increases, but a higher temperature is needed to achieve this value. Under fuel rich condition, NO reduction was accompanied with HCN formation, which must be considered to analyze the effective reduction. The CO 2 generated from pilot flame or originally contained in LCG could inhibit the NO reduction, with this effect being more pronounced at a fuel rich atmosphere. For a CO/CH 4 duel reactive LCGs, CO reduces the NO reduction ratio at lower temperature, but improves at higher temperature.
    Type of Medium: Online Resource
    ISSN: 0957-6509 , 2041-2967
    URL: Article
    DOI: 10.1177/09576509231157949
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2024892-1
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