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  • SAGE Publications  (2)
  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 2021
    In:  Foregut: The Journal of the American Foregut Society Vol. 1, No. 3 ( 2021-09), p. 197-206
    In: Foregut: The Journal of the American Foregut Society, SAGE Publications, Vol. 1, No. 3 ( 2021-09), p. 197-206
    Abstract: Esophageal motility, the science of quantifying the mechanical function of the esophagus, was initiated by Hugo Kronecker in Germany in 1882. Little progress was made until after World War II, when motility studies began in the Mayo Clinic and Boston University. After 1960, several key figures promoted the science, including Lauran Harris, Don Castell, Jerry Dodds, Tom DeMeester, Peter Kahrilas, and Ray Clouse. All were inspirational teachers and mentors as well as scientists. The technical developments from balloons and perfused catheters to the current solid-state catheters and sophisticated software has provided insights which have helped physicians to treat patients with dysfunction of the esophagus with increasing success.
    Type of Medium: Online Resource
    ISSN: 2634-5161 , 2634-5161
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
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  • 2
    In: The American Surgeon, SAGE Publications, Vol. 65, No. 10 ( 1999-10), p. 911-914
    Abstract: Stationary manometry is the gold standard for the evaluation of patients with suspected esophageal motility disorders. Comparison of videoesophagram in the evaluation of esophageal motility disorders with stationary motility has not been objectively studied. Two hundred two patients with foregut symptoms underwent stationary motility and videoesophagram. Radiographic assessment of esophageal motility was done by video recording of five 10-cc swallows of barium. Abnormal esophageal body function was defined by stasis of barium in the middle third of the esophagus on at least four swallows or stasis on at least three swallows in the distal third. Stationary manometry was performed using a five-channel water perfused system. Contraction amplitudes 〈 25 mm Hg in any of the last two channels or the presence of simultaneous or interrupted waves in 10 per cent or more were considered to be abnormal. Sixty-two patients had abnormal manometry. Thirty-four patients also demonstrated abnormal videoesophagrams for an overall sensitivity of 55 per cent. The positive predictive value was 53 per cent; specificity was 79 per cent; and negative predictive value was 80 per cent Sensitivity was greatest in patients with achalasia (94%) and scleroderma (100%) and in patients presenting with dysphagia (89%). Sensitivity was poor for nonspecific esophageal motility disorders. A videoesophagram is relatively insensitive in detecting motility disorders. It seems most useful in the detection of patients with esophageal dysfunction, for which surgical treatment is beneficial, and in those patients presenting with dysphagia.
    Type of Medium: Online Resource
    ISSN: 0003-1348 , 1555-9823
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1999
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