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  • SAGE Publications  (8)
  • 1
    In: Cancer Control, SAGE Publications, Vol. 30 ( 2023-04)
    Abstract: At present, there is no objective prognostic index available for patients with esophageal squamous cell carcinoma (ESCC) who underwent intensity-modulated radiotherapy (IMRT). This study is to develop a nomogram based on hematologic inflammatory indices for ESCC patients treated with IMRT. Methods 581 patients with ESCC receiving definitive IMRT were enrolled in our retrospective study. Of which, 434 patients with treatment-naïve ESCC in Fujian Cancer Hospital were defined as the training cohort. Additional 147 newly diagnosed ESCC patients were used as the validation cohort. Independent predictors of overall survival (OS) were employed to establish a nomogram model. The predictive ability was evaluated by time-dependent receiver operating characteristic curves, the concordance index (C-index), net reclassification index (NRI), and integrated discrimination improvement (IDI). Decision curve analysis (DCA) was performed to assess the clinical benefits of the nomogram model. The entire series was divided into 3 risk subgroups stratified by the total nomogram scores. Results Clinical TNM staging, primary gross tumor volume, chemotherapy, neutrophil-to-lymphocyte ratio and platelet lymphocyte ratio were independent predictors of OS. Nomogram was developed incorporating these factors. Compared with the 8th American Joint Committee on Cancer (AJCC) staging, the C-index for 5-year OS (.627 and .629) and the AUC value of 5-year OS (.706 and .719) in the training and validation cohorts (respectively) were superior. Furthermore, the nomogram model presented higher NRI and IDI. DCA also demonstrated that the nomogram model provided greater clinical benefit. Finally, patients with 〈 84.8, 84.8-151.4, and 〉 151.4 points were categorized into low-risk, intermediate-risk, and high-risk groups. Their 5-year OS rates were 44.0%, 23.6%, and 8.9%, respectively. The C-index was .625, which was higher than the 8 th AJCC staging. Conclusions We have developed a nomogram model that enables risk-stratification of patients with ESCC receiving definitive IMRT. Our findings may serve as a reference for personalized treatment.
    Type of Medium: Online Resource
    ISSN: 1073-2748 , 1526-2359
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2004182-2
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 2019
    In:  Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering Vol. 233, No. 2 ( 2019-02), p. 710-724
    In: Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering, SAGE Publications, Vol. 233, No. 2 ( 2019-02), p. 710-724
    Abstract: Complicated flowfields near casing in a transonic axial flow compressor rotor have been numerically investigated in this paper. Two vortex identification methods, namely the Eigenvector Method and Lambda 2 Method, are introduced as important tools for the graphical representation of the concentrated vortices arising from tip leakage flow and blade boundary layer separation. The analysis of the numerical results reveals that multiple tip vortices whose development are dependent on the variation of shock wave configuration are observed at conditions around the peak efficiency point. However, with the decrease of the massflow rate, only the well-known tip leakage vortex and the second tip vortex are left in the tip region due to the disappearance of the second shock wave. Then when the massflow rate further decreases to the stall limit, an deceleration flow region emerges downstream of the shock wave due to an increasing interaction between the first shock wave and the well-known tip leakage vortex. The tip leakage vortex further experiences a bubble-type and then spiral-type breakdown at near stall flow conditions. In addition, the validity of the two vortex identification methods is also discussed in this paper. It is found that both methods are able to identify and accentuate the concentrated streamwise vortices near casing when a vortex is not disrupted. However, if the vortex breakdown occurs, only Eigenvector Method can describe the breakdown region in a deep view.
    Type of Medium: Online Resource
    ISSN: 0954-4100 , 2041-3025
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2032759-6
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2023
    In:  Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science Vol. 237, No. 7 ( 2023-04), p. 1647-1667
    In: Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science, SAGE Publications, Vol. 237, No. 7 ( 2023-04), p. 1647-1667
    Abstract: Thin-walled workpieces are widely used in the aerospace field, and milling is the main processing method of such components. However, thin-walled workpieces are prone to vibrate during milling because of their weak stiffness, and the vibrations significantly affect the processing quality. Therefore, it is important to develop a novel milling vibration suppression method for thin-walled parts. The present work focused on the milling vibration control of a thin-walled workpiece using a semi-active magnetorheological (MR) damper. The forward dynamic model and inverse control model of the MR damper were first established, and its actuating position on the workpiece was then determined by modal analysis. The dynamic model of the MR damper at this position was built based on the proposed dynamic parameter acquisition method and used in the following semi-active control algorithm design. The effectiveness of this algorithm was verified by MATLAB/Simulink simulations. Finally, six groups of milling experiments were carried out using the non-damper, the rigid rod, the damper applied with 1-, 2-, and 3-A currents, and the semi-active control damper to validate the practical effect of the proposed algorithm. It was found that the designed semi-active control MR damper outperformed the constant-current control dampers or the rigid rod. In comparison to the non-damper experiment, the root mean square (RMS) values of milling forces in x- and y-directions decreased by 45.12% and 48.58%, respectively, and surface roughness decreased by 40.22%.
    Type of Medium: Online Resource
    ISSN: 0954-4062 , 2041-2983
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2024890-8
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  • 4
    Online Resource
    Online Resource
    SAGE Publications ; 2006
    In:  Journal of Chemical Research Vol. 2006, No. 11 ( 2006-11), p. 713-715
    In: Journal of Chemical Research, SAGE Publications, Vol. 2006, No. 11 ( 2006-11), p. 713-715
    Abstract: Three mono-substituted p-tert-butylcalix[7]arenes with various reactive substituents have been synthesised by treating p-tert-butylcalix[7] arene with doubly functional electrophiles. Two amino derivatives, 43-acetohydrazideoxy- p-tert-butylcalix[7]arene and 43- N-(2-aminoethyl)acetamideoxy- p-tert-butylcalix[7] arene were obtained by aminolysis of 43-ethoxycarbonylmethoxy- p-tert-butylcalix[7]arene with hydrazine hydrate or ethylene diamine in good yield.
    Type of Medium: Online Resource
    ISSN: 1747-5198 , 2047-6507
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2006
    detail.hit.zdb_id: 3010810-X
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  • 5
    In: Energy & Environment, SAGE Publications
    Abstract: The renewable electricity quota standard (RES) policy plays an important role in achieving sustainable and green development targets. Thus, it is essential to measure the sustainability of the electric power sectors in the context of RES. In terms of the energy and environmental efficiency (EEE) measurements, few studies divided energy inputs into renewable and non-renewable energy or explored the restricted problem of minimizing resource summation. To fill these gaps, we propose an improved fix-sum energy input data envelopment analysis (FSIDEA) model based on the adjustment strategy of weighted sum minimization of renewable energy inputs. The assurance region (AR) restriction and renewable energy input sum constraint (IC) are, respectively, imposed on the FSIDEA model to achieve the common equilibrium effective frontier (EEF). Finally, this study assesses the EEE of the electric power sectors in China's 30 main regions based on the common EEF. The result reveals that Beijing and Shanghai can be selected as benchmarks after efficiency comparison. In addition, our proposed model can compressively rank all decision-making units (DMUs) compared with traditional efficiency models.
    Type of Medium: Online Resource
    ISSN: 0958-305X , 2048-4070
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2027365-4
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  • 6
    Online Resource
    Online Resource
    SAGE Publications ; 2012
    In:  Journal of Vibration and Control Vol. 18, No. 6 ( 2012-05), p. 878-892
    In: Journal of Vibration and Control, SAGE Publications, Vol. 18, No. 6 ( 2012-05), p. 878-892
    Abstract: This paper illustrates the significance of the purity of cyclostationary signals and presents a new method for blind extraction of these signals. The advantage of the method can not only extract the cyclostationary signals from low order to high order in turn but also perform algorithm without knowing cyclic frequencies of the extracted signals. The effectiveness of the proposed method is finally demonstrated by computer simulations and experiments.
    Type of Medium: Online Resource
    ISSN: 1077-5463 , 1741-2986
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2070247-4
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  • 7
    Online Resource
    Online Resource
    SAGE Publications ; 2018
    In:  Journal of Low Frequency Noise, Vibration and Active Control Vol. 37, No. 4 ( 2018-12), p. 977-986
    In: Journal of Low Frequency Noise, Vibration and Active Control, SAGE Publications, Vol. 37, No. 4 ( 2018-12), p. 977-986
    Abstract: In order to monitor the wind turbine gearbox running state effectively, a fault diagnosis method of wind turbine gearbox is put forward based on wavelet neural network. Taking a 1.5 MW wind turbine gearbox as the target of study, the frequency spectrum of vibration signal and the fault mechanism of driving part are analyzed, and the eigenvalues of the frequency domain are extracted. A wavelet neural network model for fault diagnosis of wind turbine gearbox is established, and wavelet neural network is trained by using different feature vectors of fault types. The relationship between fault component and vibration signal is identified, and the vibration fault of wind turbine gearbox is predicted and diagnosed by network model. The analysis results show that the method can diagnose fault and fault pattern recognition of wind turbine gearbox very well.
    Type of Medium: Online Resource
    ISSN: 1461-3484 , 2048-4046
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2025887-2
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  • 8
    Online Resource
    Online Resource
    SAGE Publications ; 2021
    In:  Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy Vol. 235, No. 1 ( 2021-02), p. 44-58
    In: Proceedings of the Institution of Mechanical Engineers, Part A: Journal of Power and Energy, SAGE Publications, Vol. 235, No. 1 ( 2021-02), p. 44-58
    Abstract: Unsteady flow in the blade tip region of modern axial flow compressors is one of the sources of loss, noise, and blade vibration. In some cases, it is potentially linked to stall inception. In this paper, the complex flow fields in the blade tip region of a transonic axial flow compressor rotor have been numerically investigated. The predicted results were validated by experimental data. Analyses of monitoring results of numerical probes showed that three typical flow characteristics occurred as the operating condition approached the stability limit: no flow fluctuation at the first operating point; flow fluctuation with high frequency and low amplitude at the second operating point; flow fluctuation with low frequency and high amplitude at the third operating point. Further analysis of the tip flow field showed that the evolution of the tip leakage vortex experienced three stages as the rotor was throttled. At the first stage, the TLV did not breakdown. At the second stage, a bubble-type breakdown of the tip leakage vortex occurred. At the third stage, a spiral-type breakdown of tip leakage vortex occurred. The current study demonstrated that the flow unsteadiness that appears within the test rotor was induced by the tip leakage vortex breakdown. Furthermore, with the transformation of the vortex breakdown form, the characteristic frequency and amplitude of the flow oscillation substantially changed.
    Type of Medium: Online Resource
    ISSN: 0957-6509 , 2041-2967
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2024892-1
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