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  • SAGE Publications  (67)
  • 1
    Online Resource
    Online Resource
    Reservoir characteristics and multi-stage hydrocarbon accumulation of the Upper Triassic Yanchang Formation in the southwestern Ordos Basin, NW China
    SAGE Publications ; 2020
    In:  Energy Exploration & Exploitation Vol. 38, No. 2 ( 2020-03), p. 348-371
    Details
    In: Energy Exploration & Exploitation, SAGE Publications, Vol. 38, No. 2 ( 2020-03), p. 348-371
    Abstract: The Chang-8 and Chang-6 members of the Upper Triassic Yanchang Formation (lower part) are regarded as the main oil producing members of the Ordos Basin. Recently, new hydrocarbon discoveries have been made in the upper part of the Yanchang Formation (e.g., Chang-3) in the southwestern Ordos Basin, implying that this interval also has a good potential for hydrocarbon exploration. However, studies on the origin of the high-quality reservoir, hydrocarbon migration, and accumulation patterns remain insufficient. In this study, integrated petrological, mineralogical, and fluid inclusion tests are employed to evaluate reservoir characteristics, and reconstruct the history of hydrocarbon migration and accumulation during oil and gas reservoir formation. The results reveal that the Yanchang Formation is characterized by low porosity (8 − 14%), medium permeability (0.5 − 5 mD), and strong heterogeneity; the reservoir properties are controlled by secondary porosity. Two types of dissolution are recognized in the present study. Secondary pore formation in the lower part of the formation is related to organic acid activity, while dissolution in the upper part is mainly influenced by atmospheric fresh water associated with the unconformity surface. The Yanchang Formation underwent hydrocarbon charging in three phases: the early Early Cretaceous, late Early Cretaceous, and middle Late Cretaceous. A model for hydrocarbon migration and accumulation in the Yanchang reservoirs was established based on the basin evolution. We suggest that hydrocarbon accumulation occurred at the early stage, and that hydrocarbons migrated into the upper part of the Yanchang Formation by way of tectonic fractures and overpressure caused by continuous and episodic hydrocarbon expulsion during secondary migration, forming potential oil reservoirs during the later stage.
    Type of Medium: Online Resource
    ISSN: 0144-5987 , 2048-4054
    URL: Article
    DOI: 10.1177/0144598719870257
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2026571-2
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  • 2
    Online Resource
    Online Resource
    Aerodynamic interference test of quad tilt rotor aircraft in wind tunnel
    SAGE Publications ; 2019
    In:  Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering Vol. 233, No. 15 ( 2019-12), p. 5553-5566
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part G: Journal of Aerospace Engineering, SAGE Publications, Vol. 233, No. 15 ( 2019-12), p. 5553-5566
    Abstract: There is an obvious aerodynamic interference problem that occurs for a quad tilt rotor in near-ground hovering or in the conversion operating condition. This paper presents an aerodynamic interference test of the quad tilt rotor in a wind tunnel. A 1:35 scale model of the quad tilt rotor is used in this test. To substitute for the ground, a moveable platform is designed in a low-speed open-loop wind tunnel to simulate different flight altitudes of the quad tilt rotor in hovering or forward flight. A rod six-component force balance is used to measure the loads on the aircraft, and the flow field below the airframe is captured using particle image velocimetry. The experimental results show that the ground effect is significant when the hover height above the ground is less than the rotor diameter of the quad tilt rotor aircraft, and the maximum upload of the airframe is approximately 12% of the total vertical thrust with the appearance of obvious fountain flow. During the conversion operating condition, the upload of the airframe is reduced compared with that in the hovering state, which is affected by rotor wake and incoming flow. The aerodynamic interference test results of the quad tilt rotor aircraft have important reference value in power system selection, control system design, and carrying capacity improvement with the advantage of ground effect.
    Type of Medium: Online Resource
    ISSN: 0954-4100 , 2041-3025
    URL: Article
    DOI: 10.1177/0954410019852827
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2032759-6
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  • 3
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    Locate Damage in Long-Span Bridges Based on Stress Influence Lines and Information Fusion Technique
    SAGE Publications ; 2014
    In:  Advances in Structural Engineering Vol. 17, No. 8 ( 2014-08), p. 1089-1102
    Details
    In: Advances in Structural Engineering, SAGE Publications, Vol. 17, No. 8 ( 2014-08), p. 1089-1102
    Abstract: To ensure bridge safety and functionality under in-service conditions, detecting local abnormalities of a long-span bridge at the early stage is always a desirable but challenging task. Stress influence lines (SIL) or its derivatives are recognized as very promising indices for damage detection. Compared with bridge global responses (such as displacement and acceleration), stress/strain can be more conveniently measured and is often more sensitive to local damages. This paper explores a novel damage localization approach by synthesizing SIL measurements from multiple locations, in which Dempster-Shafer data fusion technique is utilized. Compared with the measurement from a single sensor, more reliable damage-related information with the improved sensitivity and capability in damage localization can be obtained by synthesizing the measured SILs from a number of sensors. The effectiveness of the proposed method is validated through a numerical case study of the Tsing Ma Suspension Bridge. Different hypothetical scenarios, including single-damage case, double-damage, and no-damage cases, are considered in the validation. The comparison with the damage detection results using single-sensor data clearly indicates that the data fusion technique effectively enhance the consistency in the information (e.g., damage-induced structural change) and minimize non-consistent information (e.g. “noise” effect) from multiple sensors installed close to damage. The increasing number of sensors benefits the damage detection results. Excellent damage detection accuracy can be achieved, if different types of bridge components are properly selected for the monitoring. Therefore, it is promising to use the proposed approach in this study in the damage localization of real-world long-span bridges. Parametric studies are conducted to examine the effects of parameter selections and noise levels in this approach.
    Type of Medium: Online Resource
    ISSN: 1369-4332 , 2048-4011
    URL: Article
    DOI: 10.1260/1369-4332.17.8.1089
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2026561-X
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  • 4
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    Online Resource
    Yifei Sanjie Formula or Placebo With Anlotinib as Second-Line or Above Treatment for Metastatic Non-Small-Cell Lung Cancer: Study Protocol for a Double-Blind, Placebo-Controlled Randomized Pilot Study
    SAGE Publications ; 2023
    In:  Integrative Cancer Therapies Vol. 22 ( 2023-01), p. 153473542211511-
    Details
    In: Integrative Cancer Therapies, SAGE Publications, Vol. 22 ( 2023-01), p. 153473542211511-
    Abstract: Anlotinib is used as a third-line treatment for advanced non-small-cell lung cancer (NSCLC), but has limited clinical benefits and several side effects, such as diarrhea and acneiform skin rash. Traditional Chinese Medicine (TCM) is commonly used to treat cancers in China. Chinese herbal medicines may have the potential as adjuvant therapies to reduce toxicity and improve the efficacy of treatments for NSCLC. Given the positive outcomes of basic research, we plan to evaluate whether the addition of the Chinese herbal medicine Yifei Sanjie formula (YFSJF) to anlotinib can improve the progression-free survival (PFS) of advanced NSCLC patients. Methods: A multicenter, randomized, double-blind, placebo-controlled parallel-group controlled pilot trial will be performed. Forty eligible patients will be randomized in a ratio of 1:1 to the intervention (YFSJF + anlotinib) and control (placebo + anlotinib) groups. Participants will be advised to take 12 mg/day of anlotinib on days 1 to 14 of each 21-day cycle. YFSJF or placebo will be administered (15 g twice daily) during each cycle until progression of disease (PD). The primary outcome will be progression-free survival (PFS), and the secondary outcomes will be overall survival (OS), the objective response rate (ORR), and patient-reported outcomes (PRO). Tumors will be assessed based on RECIST v. 1.1 after every 2 cycles of treatment. The M. D. Anderson Symptom Inventory-Lung Cancer (MDASI-LC) will be used to evaluate PRO at baseline and weekly thereafter until PD. Discussion: This will be the first trial to evaluate the effectiveness and safety of TCM combined with anlotinib for the treatment of NSCLC. The results of this randomized controlled trial will fill a gap in the research by showing whether YFSJF combined with anlotinib can improve PFS in NSCLC patients. Trial Registration: The study was registered on June 8th, 2021 on Chinese Clinical Registry; registration number ChiCTR2100047143. ( https://www.chictr.org.cn/index.aspx ). Ethics and Dissemination: The Ethics Committee of the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine approved the study protocol (approval no.: K2020151, 2021/08/19). The study will also be supervised and managed by the Ethics Committee.
    Type of Medium: Online Resource
    ISSN: 1534-7354 , 1552-695X
    URL: Article
    DOI: 10.1177/15347354221151147
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2101248-9
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  • 5
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    Study on mechanical properties of high damping viscoelastic dampers
    SAGE Publications ; 2019
    In:  Advances in Structural Engineering Vol. 22, No. 14 ( 2019-10), p. 2925-2936
    Details
    In: Advances in Structural Engineering, SAGE Publications, Vol. 22, No. 14 ( 2019-10), p. 2925-2936
    Abstract: The mechanical properties of the viscoelastic damper made of high damping rubber produced in China are investigated in order to provide the basis for its application. At first, the test on material properties of high damping rubber is conducted. The Mooney–Rivlin model, the Yeoh model and the Prony series are applied for simulating the nonlinear behavior of the high damping rubber with the aid of software ABAQUS. Then, three viscoelastic dampers with different sizes are tested under cyclic loading. The effects of strain amplitude and loading frequency on hysteretic behavior of dampers are analyzed. Viscoelastic dampers possess large deformation capability, stable energy-dissipation capacity and good fatigue-resisting property. The effect of strain amplitude is much more significant than loading frequency. The hysteretic behavior of the dampers is simulated by the Bouc–Wen model and the model of the equivalent stiffness and damping, respectively. The prediction results by using the Bouc–Wen model are in good agreement with the experimental results, which indicates that the Bouc–Wen model is applicable to simulate the mechanical properties of high damping viscoelastic dampers with a wide range of shear strain. As to the model of equivalent stiffness and damping, it has the advantages of clear concept and simple calculation. However, the good accuracy of prediction can be obtained only when the shear strain is not greater than 60%.
    Type of Medium: Online Resource
    ISSN: 1369-4332 , 2048-4011
    URL: Article
    DOI: 10.1177/1369433219853440
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2026561-X
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  • 6
    Online Resource
    Online Resource
    Damage Identification of Frame Structures with Joint Damage under Earthquake Excitation
    SAGE Publications ; 2014
    In:  Advances in Structural Engineering Vol. 17, No. 8 ( 2014-08), p. 1075-1087
    Details
    In: Advances in Structural Engineering, SAGE Publications, Vol. 17, No. 8 ( 2014-08), p. 1075-1087
    Abstract: Previous damage detection of frame structures mainly focuses on the detection of beam and column element damage. It has been shown that beam-column joints in frame structures are more susceptible to damage than the other members in the structure. Joint damage may be represented by the reduction of beam-column connection rigidity. Therefore, damage detection of a frame structure with joint damage includes the identification of joint connection stiffness in additional to those of beam and column stiffness, which involves the difficulty of identifying a large number of unknown structural parameters. In this paper, an algorithm based on a two-step Kalman filter approach is presented for the damage detection of frame structures with joint damage under earthquake excitation using partial measurements of structural acceleration responses. Recursive solutions for unknown structural parameters and structural state vector are derived by a two-step Kalman filter, respectively. Therefore, the number of unknown variables to be estimated in each step is reduced compared with the conventional Extended Kalman filter (EKF) approach. Structural damage is detected from the degradation of the identified stiffness values of joints, beam and column elements of frame structures. A numerical example and a lab experiment test data are used to validate the performances of the proposed algorithm for damage identification of various joint damage scenarios in frame structures under earthquake excitation.
    Type of Medium: Online Resource
    ISSN: 1369-4332 , 2048-4011
    URL: Article
    DOI: 10.1260/1369-4332.17.8.1075
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2026561-X
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  • 7
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    Risk of nonmajor bleeding upon use of direct oral anticoagulants for preventing and treating venous thromboembolism: A network meta-analysis
    SAGE Publications ; 2022
    In:  Vascular Medicine Vol. 27, No. 6 ( 2022-12), p. 565-573
    Details
    In: Vascular Medicine, SAGE Publications, Vol. 27, No. 6 ( 2022-12), p. 565-573
    Abstract: Direct oral anticoagulants (DOACs) are associated with bleeding. Patients often stop taking DOACs due to nonmajor bleeding, which may lead to venous thromboembolism (VTE) recurrence. We aimed to determine the risk of nonmajor bleeding using different DOACs to prevent and treat VTE. Methods: PubMed, Embase, Web of Science, and Cochrane Library databases were searched from inception until January 6, 2021. The incidence of clinically relevant nonmajor bleeding and minor bleeding was investigated. In frequentist-based network meta-analysis, we analyzed the odds ratio (OR) with 95% CI and the surface under the cumulative ranking curves (SUCRA). Results: Twenty-seven randomized controlled trials (RCTs) (involving 64,493 patients) were included. For preventing VTE, the risk for clinically relevant nonmajor bleeding was lowest for apixaban, followed by that for low-molecular weight heparin (LMWH), dabigatran, edoxaban, and rivaroxaban. The risk for minor bleeding was lowest for apixaban, followed by that for rivaroxaban, LMWH, dabigatran, and edoxaban. For treating VTE, the risk for clinically relevant nonmajor bleeding was also lowest for apixaban, followed by that for edoxaban, vitamin K antagonists (VKAs), and rivaroxaban. The risk for minor bleeding was lowest for apixaban, followed by that for rivaroxaban and VKAs. Conclusions: Regardless of whether it was used for preventing or treating VTE, apixaban had the lowest risk of nonmajor bleeding. This suggests that apixaban may have a lower risk of nonmajor bleeding than other anticoagulants and may help provide some clinical reference for choosing a more appropriate drug for the patient.
    Type of Medium: Online Resource
    ISSN: 1358-863X , 1477-0377
    URL: Article
    DOI: 10.1177/1358863X221115213
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2027562-6
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  • 8
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    Hard chromium coating effects on tribological performances for nonlubricated and lubricated spindle of cotton picker
    SAGE Publications ; 2016
    In:  Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications Vol. 230, No. 2 ( 2016-04), p. 446-453
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part L: Journal of Materials: Design and Applications, SAGE Publications, Vol. 230, No. 2 ( 2016-04), p. 446-453
    Abstract: A spindle is the core component of a cotton picker, whose performance affects the efficiency of picking cotton directly. To enhance the spindle’s strength and wear resistance, it is desired to add a coating on the spindle surface. In the present study, the tribological mechanism of hard chromium coating used for the spindle made of 20CrMnTi is investigated under the dry sliding and oil lubrication conditions. Experimental results show that conclusions about the tribological mechanism of the hard chromium coating under a dry sliding condition are not completely suitable for the lubricated spindle.
    Type of Medium: Online Resource
    ISSN: 1464-4207 , 2041-3076
    URL: Article
    DOI: 10.1177/1464420715577234
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2016
    detail.hit.zdb_id: 2032772-9
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  • 9
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    Repetitive transcranial magnetic stimulation as an alternative therapy for dysphagia after stroke: a systematic review and meta-analysis
    SAGE Publications ; 2017
    In:  Clinical Rehabilitation Vol. 31, No. 3 ( 2017-03), p. 289-298
    Details
    In: Clinical Rehabilitation, SAGE Publications, Vol. 31, No. 3 ( 2017-03), p. 289-298
    Abstract: A meta-analysis and systematic review was conducted to investigate the potential effects of repetitive transcranial magnetic stimulation on dysphagia in patients with stroke, including different parameters of frequency and stimulation site. Methods: PubMed, Embase, MEDLINE databases and the Cochrane Library, were searched for randomized controlled studies of repetitive transcranial magnetic stimulation treatment of dysphagia published before March 2016. Results: Six clinical randomized controlled studies of a total of 163 stroke patients were included in this meta-analysis. A significant effect size of 1.24 was found for dysphagic outcome (mean effect size, 1.24; 95% confidence interval (CI), 0.67–1.81). A subgroup analysis based on frequency showed that the clinical scores were significantly improved in dysphagic patients with low frequency repetitive transcranial magnetic stimulation treatment ( P  〈  0.05) as well as high frequency repetitive transcranial magnetic stimulation treatment ( P  〈  0.05). A stimulation site stratified subgroup analysis implied significant changes in stroke patients with dysphagia for the unaffected hemisphere ( P  〈  0.05) and the bilateral hemisphere stimulation ( P  〈  0.05), but not for the affected hemisphere ( P  〉  0.05). The analysis of the follow-up data shows that patients in the repetitive transcranial magnetic stimulation groups still maintained the therapeutic benefit of repetitive transcranial magnetic stimulation four weeks after the last session of repetitive transcranial magnetic stimulation therapy ( P  〈  0.05). Conclusion: This meta-analysis indicates that repetitive transcranial magnetic stimulation has a positive effect on dysphagia after stroke. Compared with low-frequency repetitive transcranial magnetic stimulation, high-frequency repetitive transcranial magnetic stimulation may be more beneficial to the patients. This meta-analysis also supports that repetitive transcranial magnetic stimulation on an unaffected – or bilateral – hemisphere has a significant therapeutic effect on dysphagia.
    Type of Medium: Online Resource
    ISSN: 0269-2155 , 1477-0873
    URL: Article
    DOI: 10.1177/0269215516644771
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2028323-4
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  • 10
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    Distribution-free models for latent mixed population responses in a longitudinal setting with missing data
    SAGE Publications ; 2019
    In:  Statistical Methods in Medical Research Vol. 28, No. 10-11 ( 2019-11), p. 3273-3285
    Details
    In: Statistical Methods in Medical Research, SAGE Publications, Vol. 28, No. 10-11 ( 2019-11), p. 3273-3285
    Abstract: Many biomedical and psychosocial studies involve population mixtures, which consist of multiple latent subpopulations. Because group membership cannot be observed, standard methods do not apply when differential treatment effects need to be studied across subgroups. We consider a two-group mixture in which membership of latent subgroups is determined by structural zeroes of a zero-inflated count variable and propose a new approach to model treatment differences between latent subgroups in a longitudinal setting. It has also been incorporated with the inverse probability weighted method to address data missingness. As the approach builds on the distribution-free functional response models, it requires no parametric distribution model and thereby provides a robust inference. We illustrate the approach with both real and simulated data.
    Type of Medium: Online Resource
    ISSN: 0962-2802 , 1477-0334
    URL: Article
    DOI: 10.1177/0962280218801123
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2001539-2
    detail.hit.zdb_id: 1136948-6
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