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  • 1
    Online Resource
    Online Resource
    Serum 25-hydroxyvitamin D Levels are Lower in Chronic Rhinosinusitis with Nasal Polyposis and are Correlated with Disease Severity in Taiwanese Patients
    SAGE Publications ; 2013
    In:  American Journal of Rhinology & Allergy Vol. 27, No. 6 ( 2013-11), p. e162-e165
    Details
    In: American Journal of Rhinology & Allergy, SAGE Publications, Vol. 27, No. 6 ( 2013-11), p. e162-e165
    Abstract: Vitamin D deficiency is reported to be associated with increased incidence of allergic airway diseases and is correlated with the severity of asthma. This study was designed to determine if serum Vitamin D level is lower in chronic rhinosinusitis with nasal polyposis (CRSwNP) patients and if low serum Vitamin D level is correlated with the severity of CRSwNP. Methods New CRSwNP patients undergoing elective endoscopic sinus surgery were recruited. Patients with malignancies or asthma were excluded. Twenty chronic rhinosinusitis without nasal polyposis (CRSsNP) patients were used as control. Demographic characteristic information was collected. The severity of CRSwNP was assessed with the Lund-Mackay (LM) score and polyp grading system. Vitamin D status was assessed by measuring circulating 25-hydroxyvitamin D (25OHD) by using commercial chemiluminescence immunoassay. Data were stratified by factors known to affect serum 25OHD, including sex, race, and body mass index. Results Serum 25OHD levels (ng/mL ± SD) were significantly lower in patients with CRSwNP (21.4 ± 5.7) than in those with CRSsNP (28.8 ± 6.2; p 〈 0.001). The incidences of vitamin D deficiency ( 〈 20 ng/mL) in CRSwNP and CRSsNP patients were 45.5 and 6.3%; however, the incidences of vitamin D insufficiency (20–30 ng/mL) in these patients were 50.0 and 62.5%, respectively. A significantly negative relationship was found between serum 25OHD level and polyp grade (r = −0.63; p = 0.001), indicating lower serum 25OHD was associated with higher polyp grade. Serum 25OHD was inversely related to both LM score and total IgE level as well; however, statistical significance was not found. Conclusion A significantly lower vitamin D level was found in a group of Taiwanese CRSwNP patients, which revealed an association with greater nasal polyp size. Serum vitamin D levels could be added to the routine workup of patients suffering from CRS and these data could be used to potentially help determine the disease severity.
    Type of Medium: Online Resource
    ISSN: 1945-8924 , 1945-8932
    URL: Article
    DOI: 10.2500/ajra.2013.27.3948
    RVK:
    XA 20278
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2554548-6
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  • 2
    Online Resource
    Online Resource
    Respondent-Driven Sampling With Hard-to-Reach Emerging Adults: An Introduction and Case Study With Rural African Americans
    SAGE Publications ; 2011
    In:  Journal of Adolescent Research Vol. 26, No. 1 ( 2011-01), p. 30-60
    Details
    In: Journal of Adolescent Research, SAGE Publications, Vol. 26, No. 1 ( 2011-01), p. 30-60
    Abstract: Obtaining representative samples from populations of emerging adults who do not attend college is challenging for researchers. This article introduces respondent-driven sampling (RDS), a method for obtaining representative samples of hard-to-reach but socially interconnected populations. RDS combines a prescribed method for chain referral with a mathematical model to adjust for potential sampling bias. A case study is presented of the use of RDS to obtain a sample of rural African American emerging adults and to document the feasibility, effectiveness, and efficiency of the method with this population. RDS-related findings indicate that rural African American emerging adults form interconnected social networks that are appropriate for using RDS. RDS procedures are an acceptable and relatively efficient strategy for rural African Americans that is likely to yield more representative samples than traditional snowball sampling and provides data on potential sampling biases for planning multivariate analyses.
    Type of Medium: Online Resource
    ISSN: 0743-5584 , 1552-6895
    URL: Article
    DOI: 10.1177/0743558410384734
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2011
    detail.hit.zdb_id: 1500220-2
    SSG: 5,2
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  • 3
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    Multivariate prognostic index and triplet regimen efficacy predictive index in locally advanced and metastatic gastric cancer: pooled analysis from three clinical trials using individual patient data
    SAGE Publications ; 2024
    In:  Therapeutic Advances in Medical Oncology Vol. 16 ( 2024-01)
    Details
    In: Therapeutic Advances in Medical Oncology, SAGE Publications, Vol. 16 ( 2024-01)
    Abstract: Plain language summary A prognostic index in locally advanced and metastatic gastric cancer To date, no recognized systematic prognostic score has been established for advanced gastric cancer (AGC). Our research aims to construct an effective prognostic index to predict overall survival (OS) for AGC patients to aid clinical decision-making and individual risk stratification. In our research, seven prognostic factors were identified: primary tumor site in the non-proximal gastric area, signet-ring cell carcinoma (SRCC)/mucinous carcinoma, peritoneal metastasis, neutrophil count higher than the upper limit of normal value (ULN), lymphocyte count lower than the lower limit of normal value, lactate dehydrogenase level higher than the ULN, and alkaline phosphatase level higher than the ULN as significant for prognosis. A prognostic index named the Fudan advanced gastric cancer prognostic risk score (FARS) index was constructed, and patients in the high-risk group had significantly shorter OS than those in low-risk group (median OS, 15.5 months vs. 8.0 months, P 〈 0.001). Moreover, three triplet regimen efficacy parameters were identified: SRCC/mucinous adenocarcinoma, primary tumor location in the non-proximal gastric area, and peripheral neutrophil count higher than the ULN; a TRIS index was subsequently conducted. In patients with any two of the three parameters, the triplet regimen showed significantly longer OS than the doublet regimen (P = 0.018).
    Type of Medium: Online Resource
    ISSN: 1758-8359 , 1758-8359
    URL: Article
    DOI: 10.1177/17588359241233982
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2024
    detail.hit.zdb_id: 2503443-1
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  • 4
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    Online Resource
    The impact of adolescent parentification on family relationship and civic engagement
    SAGE Publications ; 2021
    In:  Journal of Social Work Vol. 21, No. 6 ( 2021-11), p. 1413-1432
    Details
    In: Journal of Social Work, SAGE Publications, Vol. 21, No. 6 ( 2021-11), p. 1413-1432
    Abstract: This study examined the relationships between parentification, family relationship, political interest, and civic beliefs using a large sample of Taiwanese adolescents. Data were collected from 1648 junior and senior high school students in Taichung City, Taiwan. Parentification was hypothesized to positively affect family relationship, which in turn influences adolescents’ political interest and civic beliefs. A series of structural equation models were constructed and tested. Implications of the findings for practice and policy-making are discussed. Findings Two dimensions of parentification, instrumental and emotional caregiving, were found to be positively associated with the parent–child relationship while perceived unfairness was negatively associated with the family relations. Family relationship was positively related to youth’s civic beliefs as well as their political interests. Potential gender, age (junior high/senior high), and family (living with/not with both parents) effects were examined through multi-group comparisons. The model was robust with minor differences between gender, age, and family type subgroups. Applications Social workers should recognize the developmental benefits of parentification and utilize such experiences when working with adolescents. With cultural sensitivity, a healthy inter-dependence between youth and parents can be appreciated as a source of strength, which facilitates young people’s civic responsibility and concern for public affairs beyond family.
    Type of Medium: Online Resource
    ISSN: 1468-0173 , 1741-296X
    URL: Article
    DOI: 10.1177/1468017320955249
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2101236-2
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  • 5
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    Online Resource
    Effect of the diesel injection timing and the pilot quantity on the combustion characteristics and the fine-particle emissions in a micro-diesel pilot-ignited natural-gas engine
    SAGE Publications ; 2013
    In:  Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering Vol. 227, No. 8 ( 2013-08), p. 1142-1152
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering, SAGE Publications, Vol. 227, No. 8 ( 2013-08), p. 1142-1152
    Abstract: Natural gas is a potential alternative to conventional liquid fuels for utilization in automotive internal combustion engines. Its utilization can significantly reduce the levels of nitrogen oxide and particulate matter emissions from dual-fuel diesel/natural-gas engines. However, this reduction in the particulate matter emissions may induce an increase in the quantity of particles of smaller size, which are harmful to human health. The engine parameters, namely the diesel injection timing and the pilot quantity directly, affect the homogeneity of the fuel–air mixture, the spatial distribution of initial ignition centres and the quantity of initial ignition centres. In this paper, the effects of these two engine parameters on the combustion and the particle emission characteristics of micro-diesel pilot-ignited natural-gas fuel are investigated. The combustion parameters were calculated from the cylinder pressure data. An electrical low-pressure impactor was employed to measure the particle number concentration and particle size distribution. Experimental results indicate that the ignition delay period is prolonged and the particle number concentration progressively increases with advance of the injection timing, while the particle mass concentration undergoes a steady decrease and then a rapid increase. On the other hand, increasing the pilot diesel quantity can shorten the ignition delay period and enhance the burning rate. Meanwhile, the particle mass concentration increases evidently but the particle number concentration decreases unexpectedly. It should be noted that the total number of fine particles is sensitive to advancing injection and decreasing pilot mass, especially above the 20° crank angle before top dead centre injection timing and below the basic pilot mass.
    Type of Medium: Online Resource
    ISSN: 0954-4070 , 2041-2991
    URL: Article
    DOI: 10.1177/0954407013480452
    RVK:
    ZO 4200
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2032754-7
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  • 6
    Online Resource
    Online Resource
    Elucidating Parenting Processes That Influence Adolescent Alcohol Use : A Qualitative Inquiry
    SAGE Publications ; 2013
    In:  Journal of Adolescent Research Vol. 28, No. 1 ( 2013-01), p. 3-30
    Details
    In: Journal of Adolescent Research, SAGE Publications, Vol. 28, No. 1 ( 2013-01), p. 3-30
    Abstract: This study’s purpose was to learn why some youth who participated in the Strong African American Families (SAAF) program increased alcohol use after 2 years whereas other youth did not. Using a sample of 28 African American caregiver-youth dyads, the authors collected qualitative data to explore these issues. Findings underscore the importance of caregivers’ practicing vigilant monitoring to keep their adolescents from experimenting with alcohol. Recommendations for limiting access to alcohol and encouraging vigilant parenting are discussed.
    Type of Medium: Online Resource
    ISSN: 0743-5584 , 1552-6895
    URL: Article
    DOI: 10.1177/0743558412447851
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 1500220-2
    SSG: 5,2
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  • 7
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    Online Resource
    A Study on Space Masts Based on Octahedral Truss Family
    SAGE Publications ; 2001
    In:  International Journal of Space Structures Vol. 16, No. 1 ( 2001-03), p. 75-82
    Details
    In: International Journal of Space Structures, SAGE Publications, Vol. 16, No. 1 ( 2001-03), p. 75-82
    Abstract: Octahedral truss is a kind of geometry-rich structure, which can be used extensively in space missions. Regular octahedron is the basis of other various octahedral trusses. Firstly, five basic units of octahedral truss or derivatives are proposed, and the structural performances are investigated briefly. Mechanism features and formations are then studied for fundamental deployable modules in conjunction with the basic units. And knowledge of geometry is formulated in detail for different deployable modules, especially for variable geometry truss and tensegrity. The corresponding mast formations are also developed. Finally, kinematic analysis approach is proposed concisely for statically determinate deployable octahedral truss, and spares matrix storage and reduced matrix technique are employed to improve the computation efficiency.
    Type of Medium: Online Resource
    ISSN: 0956-0599 , 2059-8033
    URL: Article
    DOI: 10.1260/0266351011495331
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2001
    detail.hit.zdb_id: 2030949-1
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  • 8
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    Online Resource
    Parenting Practices and Child Adjustment in Different Types of Households : A Study of African American Families
    SAGE Publications ; 2006
    In:  Journal of Family Issues Vol. 27, No. 6 ( 2006-06), p. 803-825
    Details
    In: Journal of Family Issues, SAGE Publications, Vol. 27, No. 6 ( 2006-06), p. 803-825
    Abstract: This article uses a sample of 867 African American households to investigate differences in parenting practices and child outcomes by type of household. Results indicate that mothers provide similar levels of parenting regardless of family structure. Secondary caregivers, however, show a great deal of variation in quality of parenting. Fathers and grandmothers engage in the highest quality parenting, stepfathers the poorest, with other relatives falling in between. These differences in parenting do not explain family structure differences in child behavior problems. Results suggest that children do best when there are two caregivers in the household, although stepfathers are an exception to this rule. Child behavior problems are found to be no greater in either mother-grandmother or mother-relative families than in households with two biological parents. In terms of risk for child behavior problems, these family forms seem to be functionally equivalent.
    Type of Medium: Online Resource
    ISSN: 0192-513X , 1552-5481
    URL: Article
    DOI: 10.1177/0192513X05285447
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2006
    detail.hit.zdb_id: 1494068-1
    SSG: 3,4
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  • 9
    Online Resource
    Online Resource
    Self-regulatory Problems Mediate the Association of Contextual Stressors and Unprotected Intercourse among Rural, African American, Young Adult Men
    SAGE Publications ; 2011
    In:  Journal of Health Psychology Vol. 16, No. 1 ( 2011-01), p. 50-57
    Details
    In: Journal of Health Psychology, SAGE Publications, Vol. 16, No. 1 ( 2011-01), p. 50-57
    Abstract: In this brief report, the hypothesis that self-regulatory problems would mediate the association between contextual stressors and unprotected intercourse among rural African American young adult men was investigated. Family support and religiosity were hypothesized to ameliorate the influence of contextual stressors on self-regulatory problems. Hypotheses were tested on 79 sexually active men from a sample recruited with Respondent Driven Sampling; episodes of unprotected intercourse constituted the criterion variable. Analyses supported the mediating role of self-regulatory problems in linking young adult men’s contextual stressors with a heightened likelihood of unprotected intercourse. Religious involvement and family support interacted with contextual stressors to predict diminished associations with self-regulatory problems.
    Type of Medium: Online Resource
    ISSN: 1359-1053 , 1461-7277
    URL: Article
    DOI: 10.1177/1359105310367831
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2011
    detail.hit.zdb_id: 2021897-7
    SSG: 5,2
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  • 10
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    Online Resource
    Effect of Apatinib on Serum CD4+CD25+ T cells, NK Cells, and T Cells Subgroup in Malignant Tumor
    SAGE Publications ; 2019
    In:  Technology in Cancer Research & Treatment Vol. 18 ( 2019-01-01), p. 153303381989366-
    Details
    In: Technology in Cancer Research & Treatment, SAGE Publications, Vol. 18 ( 2019-01-01), p. 153303381989366-
    Abstract: The immune makers including CD4+CD25+ T cells, natural killer cells, and T cells subgroup were retrospectively analyzed to find the relationship between apatinib and the immune system in the patients treated with apatinib. Method: Forty-two patients with advanced malignant tumors orally took apatinib as treatment and 16 patients with the same situation did not take apatinib as a control group. These patients were all included in the study, and they orally received apatinib 500 mg daily as monotherapy or combination. The treatment was continued until disease progression or intolerable toxicity. CD4+CD25+ T cells, natural killer cells, and T cells subgroup were detected before and 1 month after therapy for all the patients. The relationship between the changing number of immune cells and progression-free survival was analyzed in this study. Result: For the apatinib group, the rate of CD4+CD25+ T cells significantly increased ( P = .048). The median progression-free survival was 3.25 months for the 42 patients. The median progression-free survival in the patients with the rate of CD4+CD25+ T cells increased and decreased was 5.8 months and 2.9 months, respectively ( P = .012). Multivariate analysis found the increased rate of CD4+CD25+ T cells was an independent prognostic factor for a longer progression-free survival. The rate of natural killer cells and T cells subgroup did not change much after apatinib therapy, and they were not independent prognostic factors for progression-free survival. Conclusion: The rate of CD4+CD25+ T cells is very important in patients with apatinib treatment. The changing number of CD4+CD25+ T cells may be a good indicator for apatinib prognosis. Natural killer cells and T cells subgroup did not change much after apatinib, and they were not independent prognostic factors for progression-free survival.
    Type of Medium: Online Resource
    ISSN: 1533-0346 , 1533-0338
    URL: Article
    DOI: 10.1177/1533033819893667
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2146365-7
    detail.hit.zdb_id: 2220436-2
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