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  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 2017
    In:  Proceedings of the Institution of Mechanical Engineers, Part O: Journal of Risk and Reliability Vol. 231, No. 2 ( 2017-04), p. 146-154
    In: Proceedings of the Institution of Mechanical Engineers, Part O: Journal of Risk and Reliability, SAGE Publications, Vol. 231, No. 2 ( 2017-04), p. 146-154
    Abstract: This article studies a case of the banking company in Taiwan to measure the service performance by adopting reliability analysis. The service performance focuses on sending transaction data from one source (headquarters) to multiple sinks (bank branches) for a banking company transmission system. A stochastic flow network consisting of edges (transmission lines) and nodes (Internet data center or bank branches) is constructed to model such a computer system. The service-level agreement is a contract that requirements should be promised by the Internet service provider. Also, the bank needs to satisfy the customers’ requirements through the banking company transmission system. System reliability, which is defined as the probability of demand satisfaction, is studied as a key performance indicator for measuring service level of the banking company transmission system. Subsequently, sensitivity analysis is adopted to investigate the key transmission line that affects the system reliability most significantly. The system supervisor can make a decision for banking company transmission system to enhance the important edges for improving system reliability.
    Type of Medium: Online Resource
    ISSN: 1748-006X , 1748-0078
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2246471-2
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 2018
    In:  Proceedings of the Institution of Mechanical Engineers, Part O: Journal of Risk and Reliability Vol. 232, No. 3 ( 2018-06), p. 248-261
    In: Proceedings of the Institution of Mechanical Engineers, Part O: Journal of Risk and Reliability, SAGE Publications, Vol. 232, No. 3 ( 2018-06), p. 248-261
    Abstract: Transmission quality of a communication/computer system is a high-level objective of system supervisors. Therefore, transmission reliability improvement or optimization is an important issue for many organizations. One way to maximize transmission reliability is to model the system as a stochastic communication network including arcs and nodes and then determine the optimal component redundancy allocation. However, modern components are highly reliable. Thus, a decision maker may be more concerned about cost than reliability. This article considers cost-oriented component allocation subject to a reliability threshold and correlated failures characterized by a correlated binomial distribution model. To solve this problem, we employ a genetic algorithm to search for the optimal component redundancy allocation possessing minimal allocation cost. The computational efficiency of the genetic algorithm–based method is demonstrated through several benchmark networks and compared against several popular soft computing algorithms.
    Type of Medium: Online Resource
    ISSN: 1748-006X , 1748-0078
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2018
    detail.hit.zdb_id: 2246471-2
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 2013
    In:  Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture Vol. 227, No. 9 ( 2013-09), p. 1382-1392
    In: Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture, SAGE Publications, Vol. 227, No. 9 ( 2013-09), p. 1382-1392
    Abstract: This article addresses reliability evaluation for a production system with intersectional lines and multiple reworking actions, where the reliability is the probability of demand satisfaction. First, the production system is constructed as a capacitated-flow production network by the revised graphical transformation and decomposition techniques. Capacity analysis is implemented to determine the input flow of each workstation subsequently. Second, two algorithms, including a general algorithm, are proposed to generate all minimal capacity vectors that workstations should provide to satisfy demand. The reliability is derived in terms of such vectors accordingly. A real-world case of printed circuit board production system is utilized to demonstrate the performance evaluation procedure.
    Type of Medium: Online Resource
    ISSN: 0954-4054 , 2041-2975
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2013
    detail.hit.zdb_id: 2032745-6
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  • 4
    In: Science Progress, SAGE Publications, Vol. 106, No. 2 ( 2023-04), p. 003685042311712-
    Abstract: During the machining process, the computer numerical control machine is susceptible to variations in ambient temperature, cutting heat, and friction within the transmission parts, which generate different heat sources. These heat sources affect the machine structure in different ways, causing deformation of the machine and displacement of the tooltip and workpiece position, ultimately resulting in deviations in machining accuracy. The amount of thermal drift depends on several factors, including the material of the machine components, the cutting conditions, the duration of the machining process, and the environment. This study proposes a hybrid optimization algorithm to optimize the thermal variables of computer numerical control machine tool spindles. The proposed approach combines regression analysis and fuzzy inference to model the thermal behavior of the spindle. Spindle speed and 16 temperature measurement points distributed on the machine are input factors, while the spindle's axial thermal error is considered an output factor. This study develops a regression equation for each speed to account for the different temperature rise slopes and spindle thermal variations at different speeds. The experimental results show that the hybrid thermal displacement compensation framework proposed in this study effectively reduces the thermal displacement error caused by spindle temperature variation. Furthermore, the study finds that the model can be adapted to significant variations in environmental conditions by limiting the machining speed range, which significantly reduces the amount of data needed for model adaptation and shortens the adaptation time of the thermal displacement compensation model. As a result, this framework can indirectly improve product yield. The effects observed in this study are remarkable.
    Type of Medium: Online Resource
    ISSN: 0036-8504 , 2047-7163
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2483680-1
    detail.hit.zdb_id: 2199376-2
    SSG: 11
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  • 5
    Online Resource
    Online Resource
    SAGE Publications ; 2020
    In:  Proceedings of the Institution of Mechanical Engineers, Part O: Journal of Risk and Reliability Vol. 234, No. 4 ( 2020-08), p. 636-648
    In: Proceedings of the Institution of Mechanical Engineers, Part O: Journal of Risk and Reliability, SAGE Publications, Vol. 234, No. 4 ( 2020-08), p. 636-648
    Abstract: Checkpointing is a technique to back up work at periodic intervals so that if computation fails, it will not be necessary to restart from the beginning but will instead be able to restart from the latest checkpoint. Performing checkpointing operations requires time. Therefore, it is necessary to consider the tradeoff between the time to perform checkpointing operations and the time saved when computation restarts at a checkpoint. This article presents a method to model the impact of correlated failures on an application that performs a specified amount of computation and implements checkpointing operations at equidistant periods during this computation. We develop a Markov model and superimpose a correlated life distribution. Two cases are considered. The first assumes that reaching a checkpoint resets the failure distribution. The second allows the probability of failure to progress. We illustrate the approach through a series of examples. The results indicate that correlation can negatively impact checkpointing, necessitating more frequent checkpointing and increasing the total time required, but that the approach can still identify the optimal number of equidistant checkpoints, despite this correlation.
    Type of Medium: Online Resource
    ISSN: 1748-006X , 1748-0078
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2246471-2
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  • 6
    Online Resource
    Online Resource
    SAGE Publications ; 2017
    In:  Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture Vol. 231, No. 7 ( 2017-05), p. 1264-1274
    In: Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture, SAGE Publications, Vol. 231, No. 7 ( 2017-05), p. 1264-1274
    Abstract: This article presents a topological technique for evaluating the performance of a hybrid flow-shop production system. Such a production system is modeled as a hybrid production network; each workstation of the hybrid production network has stochastic capacity levels. This article evaluates the probability of demand satisfaction as a performance indicator for the hybrid production network, in which the network has multiple lines and each workstation has a distinct defect rate. First, a topological transformation is utilized to transform a hybrid flow-shop production system into a network-structured hybrid production network; then, the hybrid production network is decomposed into several routes for flow analysis. Second, two procedures for two models (Model I considers the hybrid production network with parallel lines, Model II with intersectional lines) are designed to generate the minimal required capacity for workstations to satisfy the given demand. The probability of demand satisfaction is subsequently evaluated in terms of the minimal required capacities by applying the recursive sum of disjoint products algorithm.
    Type of Medium: Online Resource
    ISSN: 0954-4054 , 2041-2975
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2032745-6
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  • 7
    In: Cell Transplantation, SAGE Publications, Vol. 20, No. 6 ( 2011-07), p. 893-908
    Abstract: Embryonic stem (ES) cell transplantation represents a potential means for the treatment of degenerative diseases and injuries. As appropriate distribution of transplanted ES cells in the host tissue is critical for successful transplantation, the exploration of efficient strategies to enhance ES cell migration is warranted. In this study we investigated ES cell migration under the influence of various extracellular matrix (ECM) proteins, which have been shown to stimulate cell migration in various cell models with unclear effects on ES cells. Using two mouse ES (mES) cell lines, ESC 26GJ9012-8-2 and ES-D3 GL, to generate embryoid bodies (EBs), we examined the migration of differentiating cells from EBs that were delivered onto culture surfaces coated with or without collagen I, collagen IV, Matrigel, fibronectin, and laminin. Among these ECM proteins, collagen IV exhibited maximal migration enhancing effect. mES cells expressed α2 and β1 integrin subunits and the migration enhancing effect of collagen IV was prevented by RGD peptides as well as antibodies against α2 and β1 integrins, indicating that the enhancing effect of collagen IV on cell migration was mediated by α2β1 integrin. Furthermore, staining of actin cytoskeleton that links to integrins revealed well-developed stress fibers and long filopodia in mES cells cultured on collagen IV, and the actin-disrupting cytochalasin D abolished the collagen IV-enhanced cell migration. In addition, pretreatment of undifferentiated or differentiated mES cells with collagen IV resulted in improved engraftment and growth after transplantation into the subcutaneous tissue of nude mice. Finally, collagen IV pretreatment of osteogenically differentiated mES cells increased osteogenic differentiation-like tissue and decreased undifferentiation-like tissue in the grafts grown after transplantation. Our results demonstrated that collagen IV significantly enhanced the migration of differentiating ES cells through α2β1 integrin-mediated actin remodeling and could promote ES cell transplantation efficiency, which may be imperative to stem cell therapy.
    Type of Medium: Online Resource
    ISSN: 0963-6897 , 1555-3892
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2011
    detail.hit.zdb_id: 2020466-8
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  • 8
    In: International Journal of Immunopathology and Pharmacology, SAGE Publications, Vol. 36 ( 2022-01), p. 039463202210990-
    Abstract: Acute exacerbations (AEs) of chronic obstructive pulmonary disease (COPD) can affect health status, hospitalization and readmission rates, and disease progression. This study aimed to identify independent markers associated with COPD AEs. Methods This study included male patients with COPD and collected data regarding their AEs and baseline clinical parameters. Results We included 149 male patients. Among them, 58 were included in the year 0 high-AE group and 91 in the low-AE group. Multivariate analysis revealed that the high-AE group had higher white blood cell count, lower serum albumin level, and post-bronchodilator (BD) forced expiratory volume in one second (FEV 1 ) (%) with a combined receiver operating characteristic curve (ROC) of 0.721 ( p 〈 0.001). Additionally, 34 patients were included in the year 1 high-AE group and 70 in the low-AE group ( p 〈 0.001). Multivariate analysis revealed that the high-AE group had higher platelet count, positive asthma history, and lower pre-BD FEV 1 (%) with a combined ROC of 0.782 ( p 〈 0.001). Conclusion In male patients with COPD, baseline white blood cell count, albumin level, and post-BD FEV 1 (%) were correlated with year 0 AE; on the other hand, baseline platelet count, positive asthma history, and pre-BD FEV 1 (%) were associated with year 1 AE.
    Type of Medium: Online Resource
    ISSN: 0394-6320 , 2058-7384
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2505963-4
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  • 9
    Online Resource
    Online Resource
    SAGE Publications ; 1999
    In:  Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis Vol. 19, No. 2 ( 1999-03), p. 177-178
    In: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, SAGE Publications, Vol. 19, No. 2 ( 1999-03), p. 177-178
    Type of Medium: Online Resource
    ISSN: 0896-8608 , 1718-4304
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1999
    detail.hit.zdb_id: 2075957-5
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  • 10
    In: Chronic Respiratory Disease, SAGE Publications, Vol. 16 ( 2019-01-01), p. 147997311983828-
    Abstract: Short-term oral steroid use may improve lung function and respiratory symptoms in patients with stable chronic obstructive pulmonary disease (COPD). However, long-term oral steroid (LTOS) use is not recommended owing to its potential adverse effects. Our study aimed to investigate whether chronic use of oral steroids for more than 4 months would increase mortality and vertebral fracture risk in patients with stable COPD. A systemic search of the PubMed database was conducted, and meta-analysis was performed using Review Manager 5.3. Five studies with a total of 1795 patients showed there was an increased risk of mortality in patients using LTOS (relative risk, 1.63; 95% confidence interval (CI), 1.19–2.23; p 〈 0.0001; I 2 = 86%). In addition, four studies with a total of 17,764 patients showed there was an increased risk of vertebral fracture in patients using LTOS (odds ratio, 2.31; 95% CI, 1.52–3.50; p = 0.03; I 2 = 65%). Our meta-analysis showed LTOS was associated with increased mortality and vertebral fracture risk in patients with COPD, and this risk may be due to the adverse effects of LTOS and progression COPD.
    Type of Medium: Online Resource
    ISSN: 1479-9731 , 1479-9731
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2222367-8
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