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  • SAGE Publications  (57)
  • 1
    Online Resource
    Online Resource
    Predicting medication nonadherence risk in the Chinese type 2 diabetes mellitus population – establishment of a new risk nomogram model: a retrospective study
    SAGE Publications ; 2021
    In:  Journal of International Medical Research Vol. 49, No. 9 ( 2021-09), p. 030006052110425-
    Details
    In: Journal of International Medical Research, SAGE Publications, Vol. 49, No. 9 ( 2021-09), p. 030006052110425-
    Abstract: To investigate the risk factors of medication nonadherence in patients with type 2 diabetes mellitus (T2DM) and to establish a risk nomogram model. Methods This retrospective study enrolled patients with T2DM, which were divided into two groups based on their scores on the Morisky Medication Adherence scale. Univariate and multivariate logistic regression analyses were used to screen for independent risk factors for medication nonadherence. A risk model was then established using a nomogram. The accuracy of the prediction model was evaluated using centrality measurement index and receiver operating characteristic curves. Internal verification was evaluated using bootstrapping validation. Results A total of 338 patients with T2DM who included in the analysis. Logistic regression analysis showed that the educational level, monthly per capita income, drug affordability, the number of drugs used, daily doses of drugs and the time spent taking medicine were all independent risk factors for medication nonadherence. Based on these six risk factors, a nomogram model was established to predict the risk of medication nonadherence, which was shown to be very reliable. Bootstrapping validated the nonadherence nomogram model for patients with T2DM. Conclusions This nomogram model could be used to evaluate the risks of drug nonadherence in patients with T2DM.
    Type of Medium: Online Resource
    ISSN: 0300-0605 , 1473-2300
    URL: Article
    DOI: 10.1177/03000605211042502
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2082422-1
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  • 2
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    Impact of physiological noise in characterizing the functional MRI default-mode network in Alzheimer’s disease
    SAGE Publications ; 2021
    In:  Journal of Cerebral Blood Flow & Metabolism Vol. 41, No. 1 ( 2021-01), p. 166-181
    Details
    In: Journal of Cerebral Blood Flow & Metabolism, SAGE Publications, Vol. 41, No. 1 ( 2021-01), p. 166-181
    Abstract: The functional connectivity of the default-mode network (DMN) monitored by functional magnetic resonance imaging (fMRI) in Alzheimer's disease (AD) patients has been found weaker than that in healthy participants. Since breathing and heart beating can cause fluctuations in the fMRI signal, these physiological activities may affect the fMRI data differently between AD patients and healthy participants. We collected resting-state fMRI data from AD patients and age-matched healthy participants. With concurrent cardiac and respiratory recordings, we estimated both physiological responses phase-locked and non-phase-locked to heart beating and breathing. We found that the cardiac and respiratory physiological responses in AD patients were 3.00 ± 0.51 s and 3.96 ± 0.52 s later (both p  〈  0.0001) than those in healthy participants, respectively. After correcting the physiological noise in the resting-state fMRI data by population-specific physiological response functions, the DMN estimated by seed-correlation was more localized to the seed region. The DMN difference between AD patients and healthy controls became insignificant after suppressing physiological noise. Our results indicate the importance of controlling physiological noise in the resting-state fMRI analysis to obtain clinically related characterizations in AD.
    Type of Medium: Online Resource
    ISSN: 0271-678X , 1559-7016
    URL: Article
    DOI: 10.1177/0271678X19897442
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2039456-1
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  • 3
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    Coordinated Mobilization Matters: How DidTaiwan do it during the Covid-19 Pandemic?
    SAGE Publications ; 2021
    In:  Chinese Public Administration Review Vol. 12, No. 2 ( 2021-12), p. 160-167
    Details
    In: Chinese Public Administration Review, SAGE Publications, Vol. 12, No. 2 ( 2021-12), p. 160-167
    Abstract: The Covid-19 pandemic hit the world hard. Ensnared by a large-scale emergency unprecedented in recent history, mobilization, the classic issue of emergency management, is under stress and test. Yet Taiwan stands out in its rather limited cases of infections despite its frequent contact with mainland China and high population density. Could its mobilization have made the difference? This article traces the steps and strategies that Taiwan took to implement a coordinated mobilization. Three strategies were highlighted: awareness mobilization by declaring emergency early on, resource mobilization by preemptively controlling, boldly incentivizing and surgically distributing resources, and agility mobilization via big data and technology to optimize the response system.
    Type of Medium: Online Resource
    ISSN: 1539-6754 , 2573-1483
    URL: Article
    DOI: 10.1177/153967542101200206
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2628370-0
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  • 4
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    Late Initiation of Continuous Veno-Venous Hemofiltration Therapy is Associated with a Lower Survival Rate in Surgical Critically Ill Patients with Postoperative Acute Kidney Injury
    SAGE Publications ; 2012
    In:  The American Surgeon Vol. 78, No. 2 ( 2012-02), p. 235-242
    Details
    In: The American Surgeon, SAGE Publications, Vol. 78, No. 2 ( 2012-02), p. 235-242
    Abstract: There is controversy about the appropriate timing for renal replacement therapy in patients with acute kidney injury (AKI). We are interested in the appropriate timing for initiation of continuous renal replacement therapy in critically ill surgical patients with postoperative acute kidney injury. Seventy-three critically ill surgical patients with postoperative AKI who received continuous renal replacement therapy (CRRT) were enrolled. Indications for CRRT were: 1) AKI with hyperkalemia, 2) metabolic acidosis, 3) pulmonary edema refractory to diuretics, and 4) oliguria with progressive azotemia, especially in unstable hemodynamics. Using RIFLE (Risk, Injury, Failure, Loss, End stage) classification, patients who received CRRT in the “Risk” stage were defined as early group, whereas those in the “Injury/ Failure” stage were labeled as late group. We used continuous veno-venous hemofiltration as CRRT in this series. There were 20 patients in the early group and 53 patients in the late group. The mean ages were 61.5 ± 21.8 years versus 60.8 ± 17.5 years. The mortality rate was 50 per cent versus 84.9 per cent. There were no significant differences in demographic characteristics or type of surgery or physiological scores. Our data show that late initiation of CRRT is associated with a lower survival rate in critically ill surgical patients with postoperative AKI; however, further studies are required.
    Type of Medium: Online Resource
    ISSN: 0003-1348 , 1555-9823
    URL: Article
    DOI: 10.1177/000313481207800245
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
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  • 5
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    Effects of Neurofeedback on Cognitive Function, Productive Activity, and Quality of Life in Patients With Traumatic Brain Injury: A Randomized Controlled Trial
    SAGE Publications ; 2023
    In:  Neurorehabilitation and Neural Repair Vol. 37, No. 5 ( 2023-05), p. 277-287
    Details
    In: Neurorehabilitation and Neural Repair, SAGE Publications, Vol. 37, No. 5 ( 2023-05), p. 277-287
    Abstract: Cognitive impairment is common in patients with traumatic brain injury (TBI). Studies that have examined the effectiveness of neurofeedback (NFB) on cognitive function following TBI have had poor study designs and small sample sizes. Objectives This randomized controlled trial assessed the effects of low-resolution tomography Z-score NFB (LZNFB) and theta/beta NFB on cognitive impairment, return to productive activity, and quality of life in patients with TBI. Methods We randomly assigned 87 patients with TBI with cognitive impairment to LZNFB, theta/beta NFB, or usual care (UC) groups. Patients in both NFB groups received weekly 60-minute treatment for 10 weeks, and those in the control group received UC and telephone interviews for 10 weeks. The primary outcome was cognitive function as measured by performance on cognitive tasks; the secondary outcomes included productive activity and quality of life based on the Community Integration Questionnaire-revised (CIQ-R) and the Quality of Life after Brain Injury (QOLIBRI), respectively, at baseline and immediately after the last intervention. Results The LZNFB group exhibited significantly greater improvements in immediate recall, delayed recall, recognition memory, and selective attention compared with the UC group; the theta/beta NFB group exhibited improvements in only immediate memory and selective attention ( P 〈 .05). The total CIQ-R scores of the LZNFB group after treatment were significantly improved than those of the UC group were. Conclusion Consecutive LZNFB achieved therapeutic effects in memory, attention, and productive activity, whereas theta/beta NFB improved memory and attention in patients with TBI. This trial was prospectively registered at ClinicalTrial.gov (registration number: NCT03515317; https://clinicaltrials.gov/ct2/show/NCT03515317 ).
    Type of Medium: Online Resource
    ISSN: 1545-9683 , 1552-6844
    URL: Article
    DOI: 10.1177/15459683231170539
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2100545-X
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  • 6
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    Timing of Symptomatic Infarct Swelling Following Intravenous Thrombolysis in Acute Middle Cerebral Artery Infarction: A Case–Control Study
    SAGE Publications ; 2017
    In:  Clinical and Applied Thrombosis/Hemostasis Vol. 23, No. 7 ( 2017-10), p. 814-820
    Details
    In: Clinical and Applied Thrombosis/Hemostasis, SAGE Publications, Vol. 23, No. 7 ( 2017-10), p. 814-820
    Abstract: The risk of symptomatic infarct swelling has been reported to be higher in patients treated with recombinant tissue plasminogen activator (rt-PA). The aim of this study was to evaluate the timing of symptomatic infarct swelling after rt-PA treatment. Methods: We retrospectively analyzed 14 868 patients with acute ischemic stroke from a stroke registry databank. We recruited patients with massive middle cerebral artery (MCA) infarction and symptomatic infarct swelling and excluded those with parenchymal or symptomatic hemorrhage. Multiple linear regression and multivariate logistic regression analyses were used to estimate the impact of rt-PA on the timing of symptomatic infarct swelling. Results: A total of 23 patients with rt-PA treatment and 117 patients without rt-PA treatment were included. The rt-PA treatment group had a lower rate of coronary artery disease (8.7% vs 32.5%; P = .023), lower severity of baseline National Institutes of Health Stroke Scale score (19 vs 23; P = .014), shorter duration of infarct swelling (27.6 vs 45.4 hours; P 〈 .001), and higher rate of hemicraniectomy surgery (65.2% vs 28.2%; P =.001) than those without rt-PA treatment. After adjusting for variables in multiple linear regression analysis, rt-PA treatment and an elevated C-reactive protein level were associated with early symptomatic infarct swelling ( P = .014 and P = .041, respectively). The rt-PA treatment was an independent factor related to early symptomatic infarct swelling within 36 hours ( P = .005; odds ratio [OR]: 5.3; confidence interval [CI] : 1.65-17.0) or 48 hours ( P = .009; OR: 16.4; CI: 2.00-134). Conclusion: Intravenous rt-PA treatment may hasten the onset of cerebral edema and subsequent cerebral herniation in large MCA territory infarction.
    Type of Medium: Online Resource
    ISSN: 1076-0296 , 1938-2723
    URL: Article
    DOI: 10.1177/1076029616659693
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2230591-9
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  • 7
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    The Effects of Repeat Laparoscopic Surgery on the Treatment of Complications Resulting from Laparoscopic Surgery
    SAGE Publications ; 2012
    In:  The American Surgeon Vol. 78, No. 9 ( 2012-09), p. 926-932
    Details
    In: The American Surgeon, SAGE Publications, Vol. 78, No. 9 ( 2012-09), p. 926-932
    Abstract: Laparoscopic surgery is frequently applied in the operative management of appendicitis and symptomatic cholelithiasis because it is a minimally invasive procedure. There are, however, some complications of laparoscopic cholecystectomy (LC) and laparoscopic appendectomy (LA) that result in the need for reoperation. In the current study, we examine the effects of repeat laparoscopic surgery on the treatment of complications arising from LC/LA. From April 2005 to March 2011, we examined a cohort of patients who had received LC or LA and experienced complications that required reoperations. We focused on patients with postoperative hemorrhages, postoperative peritonitis, early postoperative small bowel obstructions (EPSBO), and biliary complications (after LC) who were treated through a repeat laparoscopic approach. The general demographics of the patients, their postoperative complications, procedures for selecting the appropriate reoperation method, and repeat laparoscopic findings are described in detail. During the 6-year period examined, 1608 patients received LC and 1486 patients received LA at the hospitals participating in this study. In patients with complications requiring reoperation, the repeat laparoscopic approach was performed successfully (without the need for further laparotomy) in 50 per cent of the patients with postoperative hemorrhage (2 of 4), 50 per cent of the patients with postoperative peritonitis (2 of 4), 75 per cent of the EPSBO patients (3 of 5), and 50 per cent the of patients with biliary complications (1 of 2). The repeat laparoscopic approach is an appropriate method for the management of complications arising from laparoscopic surgery. In patients with postoperative hemorrhage, laparoscopic hemostasis and hematoma evacuations can be performed while maintaining stable hemodynamics. In addition, laparoscopic approaches are also feasible for selective post-LC ductal injuries, EPSBO, and unconfirmed diagnoses of peritonitis after laparoscopic surgery.
    Type of Medium: Online Resource
    ISSN: 0003-1348 , 1555-9823
    URL: Article
    DOI: 10.1177/000313481207800929
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
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  • 8
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    Cutting force, Vibration, and Temperature in Drilling on a Thermoplastic Material of PEEK
    SAGE Publications ; 2023
    In:  Journal of Thermoplastic Composite Materials Vol. 36, No. 3 ( 2023-03), p. 1088-1112
    Details
    In: Journal of Thermoplastic Composite Materials, SAGE Publications, Vol. 36, No. 3 ( 2023-03), p. 1088-1112
    Abstract: Polyetheretherketone (PEEK) is one of the semi-crystalline thermoplastic polymers with excellent machinability and chemical stability applied to precise structural plates and electronic components. This study installed multiple sensors to analyze the machining characteristics in the PEEK drilling. According to the time domain signals, the effects of spindle speed and feed rate on the machining characteristics of cutting force and vibration were investigated. In addition, an infrared thermography was installed to record the temperature variation within the drilling area. The experimental hole was 2-mm diameter with a 4.5-mm depth. Experimental results showed that the effect of the feed rate on thrust force is greater than the spindle speed; drilling by a low-level spindle speed with a low-level feed rate can obtain the smallest cutting force and acceleration amplitude in the spindle axis; the temperature within the drilling area is inverse to the feed rate and a high-level feed rate is helpful for forming regular curl chips. When adequate airflow was applied during the drilling operation, the hole’s shrinkage ratio and roundness can be decreased. The data presented in this paper provide valuable references for realizing the drilling of the thermoplastic—PEEK.
    Type of Medium: Online Resource
    ISSN: 0892-7057 , 1530-7980
    URL: Article
    DOI: 10.1177/08927057211052325
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2098671-3
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  • 9
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    Conventional Western Treatment Associated With Chinese Herbal Medicine Ameliorates the Incidence of Head and Neck Cancer Among Patients With Esophageal Cancer
    SAGE Publications ; 2019
    In:  Integrative Cancer Therapies Vol. 18 ( 2019-01), p. 153473541983435-
    Details
    In: Integrative Cancer Therapies, SAGE Publications, Vol. 18 ( 2019-01), p. 153473541983435-
    Abstract: Background: Because of advances in medical treatment, the survival of cancer patients is prolonged. In line with the prolonged survival time of cancer the incidence of second primary cancer has increased. There is currently no effective way to prevent the occurrence of secondary primary cancer (SPC). Objectives: The aim of this study is to evaluate whether Chinese Herbal Medicine (CHM) is correlated with reduced occurrence of second primary cancer (SPC) of head and neck (H & N) in patients with esophageal cancer (EC). Method: We identified 15,546 patients who were diagnosed with esophageal cancer between Jan 1, 2000, and Dec 31, 2010. The patients with H & N cancer before receiving CHM were excluded. After the selection and matching process, both CHM and non-CHM cohorts each contained 850 individuals. We compared the cumulative incidence of SPC of H & N with or without CHM treatment in patients with EC by the Kaplan-Meier method. NodeXL is used to run a network analysis of CHM to examine the association between herbs and formulas. Results: Compared with non-CHM users, CHM-users showed a reduced incidence rate of SPC of H & N among the patients with EC. Reduced cumulative incidence of SPC of H & N among patients with EC was noted in the CHM cohort compared to the non-CHM cohort. The most commonly used single herbs and formulas were associated with reducing SPC occurrence. Conclusion: We propose that CHM as an adjuvant therapy may prevent the occurrence of SPC of H & N in patients with EC.
    Type of Medium: Online Resource
    ISSN: 1534-7354 , 1552-695X
    URL: Article
    DOI: 10.1177/1534735419834353
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2101248-9
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  • 10
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    A human immunodeficiency virus-seronegative acquired immunodeficiency syndrome patient with opportunistic infections: A case report
    SAGE Publications ; 2022
    In:  International Journal of STD & AIDS
    Details
    In: International Journal of STD & AIDS, SAGE Publications
    Abstract: In rare cases, people living with chronic human immunodeficiency virus (HIV) infection do not develop antibodies despite demonstrable infection. Delayed or missed diagnosis of HIV infection leads to a lack of timely therapy, resulting in rapid disease progression with opportunistic infections or malignancies. Case Report A 44-year-old Chinese man presented with sore throat, oral leukoplakia, fever, dyspnoea and diffuse ground glass-like lesions in both lungs. Serum cytomegalovirus DNA was detectable, and CD4 + T-cell count was low. The patient was suspected of being a person living with HIV despite of the repeatedly negative HIV antibody tests using enzyme-linked immunsorbent assay and Western blot. Subsequently, high-plasma HIV RNA viral load was found on two repeated tests, while HIV DNA was also positive. Thus, the patient was confirmed as presenting with HIV-seronegative acquired immunodeficiency syndrome (AIDS). The symptoms improved in response to effective anti-fungal and anti-retroviral therapy after diagnosis. Conclusion This is the third reported case of an HIV-seronegative AIDS patient in China, which are also rarely reported globally. HIV nucleic acid testing is important to screen out HIV infection, especially in those who present with severe immunodeficiency but remain HIV serogenative.
    Type of Medium: Online Resource
    ISSN: 0956-4624 , 1758-1052
    URL: Article
    DOI: 10.1177/09564624221074507
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2009782-7
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