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  • SAGE Publications  (13)
  • 1
    Online Resource
    Online Resource
    Longitudinal Studies of Blood Pressure in Children
    SAGE Publications ; 1995
    In:  Asia Pacific Journal of Public Health Vol. 8, No. 2 ( 1995-04), p. 130-133
    Details
    In: Asia Pacific Journal of Public Health, SAGE Publications, Vol. 8, No. 2 ( 1995-04), p. 130-133
    Abstract: A longitudinal study of six years was conducted to find out the pattern of longitudinal changes of blood pressure and to affirm the “tracking phenomenon” of blood pressure in children in China. We initially measured blood pressure and related parameters of 2, 946 children (aged 4-14 years) in 1981 at Fanshan county, Beijing, and then two follow-up remeasurements were conducted in 1985 and 1987, respectively. The results indicated that: the average level of blood pressure increases with age even after adjusting for height and weight; tracking coefficients of systolic blood pressure range from weak to moderate levels, increasing with age. Only 30% of the children whose systolic blood pressure was beyond the 90th percentile of the systolic pressure distribution at the first examination remained at the same region after four years. Multiple stepwise regression was used to determine factors correlated with blood pressure. Our results indicate that systolic blood pressure in children is correlated with body w eight, pulse rate, scrum glucose and HDL-C, while diastolic blood pressure is correlated only with pulse rate and serum glucose.
    Type of Medium: Online Resource
    ISSN: 1010-5395 , 1941-2479
    URL: Article
    DOI: 10.1177/101053959500800213
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1995
    detail.hit.zdb_id: 2394975-2
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  • 2
    Online Resource
    Online Resource
    Systemic Arterial Blood Pressure and Intracerebral Hemorrhage after Mechanical Thrombectomy in Anterior Cerebral Circulation
    SAGE Publications ; 2021
    In:  Journal of Investigative Medicine Vol. 69, No. 5 ( 2021-06), p. 1008-1014
    Details
    In: Journal of Investigative Medicine, SAGE Publications, Vol. 69, No. 5 ( 2021-06), p. 1008-1014
    Abstract: The relationship between systemic arterial blood pressure (BP) and intracerebral hemorrhage (ICH) after mechanical thrombectomy (MT) of the cerebral artery remains unclear. This study aimed to determine the effect of BP variables on ICH after MT in patients with acute occlusions of the anterior cerebral circulation. Patients undergoing MT due to acute occlusions of the anterior cerebral circulation were enrolled in this single-center study. Non-invasive BP data following MT were obtained within the first 24 hours, including mean, maximum, minimum, difference between maximum and minimum, SD and coefficient of variation for systolic BP (SBP) and diastolic BP (DBP) and mean arterial pressure. ICH was defined and classified according to the European Cooperative Acute Stroke Study-II. In 164 enrolled patients (median age 65 (IQR 56-75) years; 31.7% female), higher maximum (89.5 mm Hg vs 98.5 mm Hg, p=0.001) and SD (9.8 mm Hg vs 10.9 mm Hg, p=0.038) of DBP were associated with higher risk of ICH. The optimal cut-off values associated with ICH for maximum SBP were 155 mm Hg and for maximum DBP 92.5 mm Hg, respectively. Higher BP within 24 hours after MT in acute occlusions of the anterior cerebral circulation is associated with a greater risk of ICH. More studies are needed to further determine optimal BP goals in the acute phase after MT.
    Type of Medium: Online Resource
    ISSN: 1081-5589 , 1708-8267
    URL: Article
    DOI: 10.1136/jim-2020-001554
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
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  • 3
    Online Resource
    Online Resource
    Preventing the wound-induced deterioration of Yali pears by chitosan coating treatments
    SAGE Publications ; 2012
    In:  Food Science and Technology International Vol. 18, No. 2 ( 2012-04), p. 123-128
    Details
    In: Food Science and Technology International, SAGE Publications, Vol. 18, No. 2 ( 2012-04), p. 123-128
    Abstract: Yali pears ( Pyrus bretschneideri Rehd.) are susceptible to mechanical damage. In this study, the protective effects of chitosan treatments on the quality of bruised pears were evaluated. The fruit were treated with 1.5% chitosan before or after bruise damage, respectively. Then, the fruit were stored at 16 °C and 85–90% relative humidity. Postharvest quality parameters were analyzed during the storage. Bruise damage accelerated the decrease of firmness and the ratio of sugar to acid, while a delay of firmness and sugar-to-acid ratio in those pears treated with chitosan before or after was found. Meanwhile, chitosan treatments both before and after damage delayed the color changes caused by damage, inhibited disease incidence increase, and enhanced the bruise recovery during the storage. Our results suggested that chitosan treatment could be used to control the physiological responses induced by bruise damage.
    Type of Medium: Online Resource
    ISSN: 1082-0132 , 1532-1738
    URL: Article
    DOI: 10.1177/1082013211414774
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2081257-7
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  • 4
    Online Resource
    Online Resource
    Surrogate Evaluation Model for Assessing Lane Detection Reliability of Automated Vehicles in Complex Road Environments
    SAGE Publications ; 2023
    In:  Transportation Research Record: Journal of the Transportation Research Board Vol. 2677, No. 7 ( 2023-07), p. 185-195
    Details
    In: Transportation Research Record: Journal of the Transportation Research Board, SAGE Publications, Vol. 2677, No. 7 ( 2023-07), p. 185-195
    Abstract: The reliability of environmental perception is the key to ensuring the stability and safety of autonomous vehicles. Complex road environments pose attentional challenges to automated driving, especially for vehicle perception systems. Therefore, evaluating the performance of autonomous driving algorithms in complex road environments is of great significance. However, as road geometry is complex, with many factors, including curvature, slope, lane marking conditions, and so on, the existing approach in assessing an algorithm through detection tests is of low efficiency. Therefore, this study relies on failure prediction modeled by extreme gradient boosting and recursive feature elimination. An evaluation model that could accomplish a quick set of road evaluations is developed. The proposed model generates recognition reliability merely by such features as road design parameters. In addition, road curvature is the most significant environmental factor affecting the perception of autonomous vehicles. The failure rates of the algorithm in different scenarios demonstrate a negative correlation between the radius of curvature and failure perception. The partial dependence involving the radius of curvature and the perception ability is obtained. Furthermore, other features, such as missing lane lines and illumination conditions, are taken into consideration to explore the potential failure perception mode. The proposed method has a particular significance for finding the failure mode of an autonomous driving perception algorithm.
    Type of Medium: Online Resource
    ISSN: 0361-1981 , 2169-4052
    URL: Article
    DOI: 10.1177/03611981231152260
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2403378-9
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  • 5
    Online Resource
    Online Resource
    Aging state detection of viscoelastic sandwich structure using redundant second generation wavelet packet transform and fuzzy support vector data description
    SAGE Publications ; 2022
    In:  Structural Health Monitoring Vol. 21, No. 5 ( 2022-09), p. 2370-2385
    Details
    In: Structural Health Monitoring, SAGE Publications, Vol. 21, No. 5 ( 2022-09), p. 2370-2385
    Abstract: Viscoelastic sandwich structure plays an important role in mechanical equipment, nevertheless viscoelastic material inevitably suffers from gradual aging. For guaranteeing the operation safety of mechanical equipment, it is urgent to perform the aging state detection of viscoelastic sandwich structure with vibration response signal analysis. However, the structural vibration response signal is non-stationary and its variation caused by the structural aging state change is very puny, and the abnormal state samples is lacking. The vibration-based structural aging state detection has become a challenging task. Therefore, a novel method based on redundant second generation wavelet packet transform (RSGWPT) and fuzzy support vector data description (FSVDD) is proposed for this task. For extracting sensitive aging feature information, RSGWPT is introduced to process the structural vibration response signal, and multiple energy features are extracted from the frequency-band signals to reflect structural aging state change. For accurate and automatic aging state identification, by fusing fuzzy theory, FSVDD only uses the normal state samples for training and can identify the abnormal severity degrees is developed to identify the structural aging states. The proposed method is applied on a viscoelastic sandwich structure to validate its effectiveness, and different structural aging states are created through the accelerated aging of viscoelastic material. The analysis results show the outstanding performance of the proposed method.
    Type of Medium: Online Resource
    ISSN: 1475-9217 , 1741-3168
    URL: Article
    DOI: 10.1177/14759217211057587
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2101420-6
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  • 6
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    Online Resource
    A Combination of Pathological Features Identifies Crohn's Disease in Surgical Bowel Resection Specimens
    SAGE Publications ; 2023
    In:  International Journal of Surgical Pathology
    Details
    In: International Journal of Surgical Pathology, SAGE Publications
    Abstract: Diagnosis of Crohn's disease is challenging. This study aims to compare the histological features of Crohn's disease and non-Crohn's disease (other intestinal inflammatory diseases) in surgical specimens to identify a set of histologic features distinguishing Crohn's disease from non-Crohn's disease. Methods Patients with Crohn's disease (N = 171) and patients with non-Crohn's disease (N = 215) diagnosed between 2010 and 2015 who had surgical bowel resection were identified. The frequency of histological features in surgical resection specimens was compared between these two groups. Results Univariate analysis revealed that transmural inflammation, subserosal lymphoid aggregates, fissures or sinus-like structures, granulomas or granuloma-like nodules, abnormalities of the enteric nervous system, and mucosa structure alterations ( muscularis mucosa thickening or mucosal atrophy with pseudopyloric gland metaplasia) were more frequent in Crohn's disease than non-Crohn's disease cases ( p  〈  0.001 for all). Some of the above histologic features were further grouped as chronic inflammatory change which includes granulomas or granuloma-like nodules, lymphoid aggregates in the muscularis propria or subserosa, fissures or sinus-like structures, and architectural abnormality which is defined as the presence of abnormal enteric nervous system and/or mucosa structural alterations ( muscularis mucosa thickening or mucosal atrophy with pseudopyloric gland metaplasia). A combination of transmural inflammation, chronic inflammatory change, and architectural abnormality had a sensitivity of 92.4% and a specificity of 97.7% for Crohn's disease. Conclusions In surgical bowel resection specimens, a combination of transmural inflammation, chronic inflammatory change, and architectural abnormality help diagnose Crohn's disease.
    Type of Medium: Online Resource
    ISSN: 1066-8969 , 1940-2465
    URL: Article
    DOI: 10.1177/10668969231195028
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2070102-0
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  • 7
    Online Resource
    Online Resource
    Differentially Expressed mRNAs and Potential Mechanisms of Radiation-Induced TUT4 −/− Esophageal Cell Injury
    SAGE Publications ; 2022
    In:  Dose-Response Vol. 20, No. 4 ( 2022-10), p. 155932582211368-
    Details
    In: Dose-Response, SAGE Publications, Vol. 20, No. 4 ( 2022-10), p. 155932582211368-
    Abstract: Radiation-induced esophageal injury remains a limitation for the process of radiotherapy for lung and esophageal cancer patients. Esophageal epithelial cells are extremely sensitive to irradiation, nevertheless, factors involved in the radiosensitivity of esophageal epithelial cells are still unknown. Terminal uridyl transferase 4 (TUT4) could modify the sequence of miRNAs, which affect their regulation on miRNA targets and function. In this study, we used transcriptome sequencing technology to identify mRNAs that were differentially expressed before and after radiotherapy in esophageal epithelial cells. We further explored the mRNA expression profiles between wild-type and TUT4 knockout esophageal epithelial cells. Volcano and heatmap plots unsupervised hierarchical clustering analysis were performed to classify the samples. Enrichment analysis on Gene Ontology functional annotations and Kyoto Encyclopedia of Genes and Genomes pathways was performed. We annotated differential genes from metabolism, genetic information processing, environmental information processing, cellular processes, and organismal systems human diseases. The aberrantly expressed genes are significantly enriched in irradiation-related biological processes, such as DNA replication, ferroptosis, and cell cycle. Moreover, we explored the distribution of transcription factor family and its target genes in differential genes. These mRNAs might serve as therapeutic targets in TUT4-related radiation-induced esophageal injury.
    Type of Medium: Online Resource
    ISSN: 1559-3258 , 1559-3258
    URL: Article
    DOI: 10.1177/15593258221136810
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2440820-7
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  • 8
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    Online Resource
    An improved Dueling Deep Q-network with optimizing reward functions for driving decision method
    SAGE Publications ; 2023
    In:  Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering Vol. 237, No. 9 ( 2023-08), p. 2295-2309
    Details
    In: Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering, SAGE Publications, Vol. 237, No. 9 ( 2023-08), p. 2295-2309
    Abstract: Aiming at poor effects and single consideration factors of traditional driving decision-making algorithm in high-speed and complex environment, a method based on improved deep reinforcement learning (DRL) is proposed in this paper. We innovatively design and optimize the reward function of the Dueling Deep Q network (Dueling DQN), and the factors such as safety, comfort, traffic efficiency and altruism are taken into account. The weight of each influencing factor is determined by the Analytic Hierarchy Process (AHP), which makes the influence of each factor on driving behavior decision-making more acceptable. Subsequently, a decision-making model of autonomous vehicles (AVs) is built by using improved Dueling DQN. Furthermore, the action space is enriched and combined with the trajectory planner, so that AVs can take appropriate behaviors in the longitudinal and lateral directions according to the environment. The output of the decision model can be combined with the underlying controller with a view to make the AVs maneuver reasonably. The driving decision-making method in two different traffic scenarios is simulated. Moreover, the improved method compares with other methods. The results illustrate that the improved Dueling DQN can make the AVs take safe, comfortable, efficient, and altruistic behavior.
    Type of Medium: Online Resource
    ISSN: 0954-4070 , 2041-2991
    URL: Article
    DOI: 10.1177/09544070221106037
    RVK:
    ZO 4200
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2032754-7
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  • 9
    Online Resource
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    The dual discourse phenomenon and its deep logic in the rights protection of migrant workers in the Pearl River Delta
    SAGE Publications ; 2022
    In:  Economic and Industrial Democracy
    Details
    In: Economic and Industrial Democracy, SAGE Publications
    Abstract: The increasing popularity of the Internet and the rapid development of social media in China have given more power of discourse to migrant workers, who have traditionally been in a disadvantageous position in terms of labor conflict. Based on a textual analysis of a typical strike, this article finds that, during collective protest, the discourse of migrant workers is dual, as it consists of both a traditional class discourse and a modern legal discourse. When using traditional class discourse, they do so to justify their actions and win the sympathy and support of public opinion. When applying modern legal discourse, they do so to cater to the governing concept of rule by law in contemporary China and use it as a means to advocate practical economic interests. This dual discourse is a reflection of the political reality in contemporary China, and points to the contradiction faced by China’s ruling party in the transition period.
    Type of Medium: Online Resource
    ISSN: 0143-831X , 1461-7099
    URL: Article
    DOI: 10.1177/0143831X221119259
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 1498600-0
    SSG: 3,4
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  • 10
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    Identification of TUBB4A as a Prognostic Biomarker of Melanoma by Transcriptomic Data and In Vitro Experiments
    SAGE Publications ; 2023
    In:  Technology in Cancer Research & Treatment Vol. 22 ( 2023-01)
    Details
    In: Technology in Cancer Research & Treatment, SAGE Publications, Vol. 22 ( 2023-01)
    Abstract: Background: Melanoma is one of the most malignant skin carcinomas with high metastatic potential. Increasing evidence has demonstrated that β-tubulin 4A (TUBB4A) plays a key role in the development and progression of several types of human cancer. However, the potential function of TUBB4A in cutaneous melanoma remains to be determined. Methods: We first performed a differential expression analysis based on skin melanoma tissues and normal tissues from Gene Expression Omnibus (GEO) and The Cancer Genome Atlas (TCGA) datasets and then a survival analysis to identify prognostic-related key genes. We further conducted in vitro biochemical experiments to verify the functional roles of the key gene TUBB4A. Two small-molecule inhibitors of TUBB4A, Dihydroartemisinin (DHA) and Nocodazole, were used to validate the effect of TUBB4A on the apoptosis and cell cycle of melanoma cells. Results: We found that TUBB4A expression was positively correlated to the overall survival (OS) of cutaneous melanoma patients. The coexpressed genes with TUBB4A were enriched in melanoma-related pathways and functions. The experimental results showed that knockdown of TUBB4A inhibited the proliferation and migration of A375 and B16-F10 melanoma cells. Moreover, DHA and Nocodazole promoted the apoptosis of melanoma cells and blocked the melanoma tumor cell cycle in the G2/M stage. Conclusion: TUBB4A may be a prognostic biomarker and therapeutic target for melanoma.
    Type of Medium: Online Resource
    ISSN: 1533-0346 , 1533-0338
    URL: Article
    DOI: 10.1177/15330338231184842
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2146365-7
    detail.hit.zdb_id: 2220436-2
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