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  • 1
    Online Resource
    Online Resource
    SAGE Publications ; 1975
    In:  SIMULATION Vol. 25, No. 5 ( 1975-11), p. 158-162
    In: SIMULATION, SAGE Publications, Vol. 25, No. 5 ( 1975-11), p. 158-162
    Type of Medium: Online Resource
    ISSN: 0037-5497 , 1741-3133
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1975
    detail.hit.zdb_id: 2072208-4
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  • 2
    Online Resource
    Online Resource
    SAGE Publications ; 1967
    In:  Educational and Psychological Measurement Vol. 27, No. 2 ( 1967-07), p. 429-430
    In: Educational and Psychological Measurement, SAGE Publications, Vol. 27, No. 2 ( 1967-07), p. 429-430
    Type of Medium: Online Resource
    ISSN: 0013-1644 , 1552-3888
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1967
    detail.hit.zdb_id: 1500101-5
    detail.hit.zdb_id: 206630-0
    SSG: 5,2
    SSG: 5,3
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  • 3
    Online Resource
    Online Resource
    SAGE Publications ; 1967
    In:  Educational and Psychological Measurement Vol. 27, No. 2 ( 1967-07), p. 427-428
    In: Educational and Psychological Measurement, SAGE Publications, Vol. 27, No. 2 ( 1967-07), p. 427-428
    Type of Medium: Online Resource
    ISSN: 0013-1644 , 1552-3888
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1967
    detail.hit.zdb_id: 1500101-5
    detail.hit.zdb_id: 206630-0
    SSG: 5,2
    SSG: 5,3
    Location Call Number Limitation Availability
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  • 4
    In: American Journal of Rhinology & Allergy, SAGE Publications, Vol. 36, No. 4 ( 2022-07), p. 465-472
    Abstract: Fractional exhaled nitric oxide (FeNO) is a cost-effective, noninvasive point-of-care test that has proven valuable in identifying patients with lower airway inflammation and predicting the likelihood of responsiveness to inhaled corticosteroid therapy in asthma. The utility of FeNO in upper airway disease, specifically in CRS, remains to be determined. Objective The goal of this study was to test whether FeNO could serve as a noninvasive marker of sinonasal mucosal inflammation in CRS patients. Methods FeNO was obtained using a nitric oxide analyzer (NIOX VERO) as well as nasal mucus, the 22-item Sinonasal Outcome Test (SNOT-22), University of Pennsylvania Smell Identification Test (UPSIT), and Lund-Kennedy endoscopic scores concurrently in 112 CRS patients. Nasal mucus was analyzed for cytokine expression using solid-phase sandwich ELISA. Linear regression with Spearman correlation coefficient was used to determine strength of relationship between variables. Results CRS patients showed elevated FeNO levels with asthma (47.12 ± 5.21 ppb) or without asthma (43.24 ± 9.810 ppb). Elevated FeNO levels correlated with sinonasal mucosal inflammation, as determined by increased levels of CCL26 and TNFα in nasal mucus obtained from CRS patients. Furthermore, elevated FeNO levels selectively correlated with worsened SNOT-22 nasal symptoms (P = 0.03) and Lund-Kennedy endoscopic scores (P = 0.007), but did not correlate with UPSIT scores. Conclusions FeNO levels correlated with increased sinonasal mucosal inflammation and symptom severity in CRS regardless of asthma status. FeNO measurements may serve as a quick and noninvasive marker in evaluating CRS patients.
    Type of Medium: Online Resource
    ISSN: 1945-8924 , 1945-8932
    RVK:
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2554548-6
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  • 5
    In: The American Surgeon, SAGE Publications, Vol. 78, No. 3 ( 2012-03), p. 325-328
    Abstract: The objective of this study was to examine whether preoperative recommendation for specific reductions in body mass index (BMI) influenced weight loss in obese surgical patients. We retrospectively reviewed the electronic medical records of 48 patients who enrolled between January 2007 to June 2010 in an 800-calorie per day liquid meal replacement (LMR) weight loss program. Of these, 9 patients (surgical group) enrolled as a result of general surgeon-directed weight loss to enable nonbariatric surgery and 39 enrolled seeking weight loss (medical group). Patients enrolled in the LMR program before bariatric surgery were excluded from analysis. All patients were seen in the setting of a comprehensive weight loss program supervised by a medical bariatrician and followed for a period of 4 months. There were no significant differences in mean initial BMI between surgical and medical patients (41.7 ± 4.55 and 41.6 ± 8.54 kg/m 2 , respectively) or participation time in the weight loss program (120 days vs 133 days). Of the nine surgical patients, only five (56%) reached their weight goal and underwent the planned surgical procedure. Weight loss was significantly less in the surgical compared with medical patients (BMI reduction 4.03 ± 3.99 vs 7.75 ± 4.90 kg/m 2 , respectively; P 〈 0.05). Weight loss was significantly lower in patients directed to undergo BMI reduction to enable a general surgical procedure. Future studies are needed to assess factors influencing weight loss (metabolism, exercise capacity, motivation) in patients requiring weight loss to enable a surgical procedure.
    Type of Medium: Online Resource
    ISSN: 0003-1348 , 1555-9823
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
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  • 6
    In: Clinical Trials, SAGE Publications, Vol. 17, No. 1 ( 2020-02), p. 30-38
    Abstract: Cost-efficient methods are essential for successful participant recruitment in clinical trials. Patient portal messages are an emerging means of recruiting potentially eligible patients into trials. We assessed the response rate and complaint rate from direct-to-patient, targeted recruitment through patient portals of an electronic medical record for a clinical trial, and compared response rates by differences in message content. Methods: The Study to Understand Fall Reduction and Vitamin D in You (STURDY) trial is a National Institutes of Health–sponsored, community-based study of vitamin D supplementation for fall prevention in older adults conducted at Johns Hopkins. Potential participants were identified using the Epic electronic medical record at the Johns Hopkins Health System based on age (≥70 years), ZIP code (30-mile radius of study site), and prior activation of a patient portal account. We prepared a shorter message and a longer message. Both had basic information about study participation, but the longer message also contained information about the significance of the study and a personal invitation from the STURDY principal investigator. The Hopkins Institutional Review Board did not require prior consent from the patient or their providers. We calculated the response rate and tracked the number of complaints and requests for removal from future messages. We also determined response rate according to message content. Results: Of the 5.5 million individuals receiving care at the Johns Hopkins Health System, a sample of 6896 met our inclusion criteria and were sent one patient portal recruitment message between 6 April 2017 and 3 August 2017. Assessment of enrollment by this method ended on 1 December 2017. There were 116 patients who expressed interest in the study (response rate: 1.7%). Twelve (0.2%) recipients were randomized. There were two complaints (0.03%) and one request to unsubscribe from future recruitment messages (0.01%). Response rate was higher with the longer message than the shorter message (2.1% vs 1.2%; p = 0.005). Conclusion: Patient portal messages inviting seniors to participate in a randomized controlled trial resulted in a response rate similar to commercial email marketing and resulted in very few complaints or opt-out requests. Furthermore, a longer message with more content enhanced response rate. Recruitment through patient portals might be an effective strategy to enroll trial participants.
    Type of Medium: Online Resource
    ISSN: 1740-7745 , 1740-7753
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2159773-X
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  • 7
    In: Journal of Learning Disabilities, SAGE Publications, Vol. 25, No. 3 ( 1992-03), p. 179-185
    Abstract: The possible utility of Wechsler's Deterioration Index (WDI) in analyzing children's Wechsler Intelligence Scale for Children-Revised (WISC-R) results was explored in this study. Clinical records of children with learning disabilities (LD) and children with attention deficit-hyperactivity disorder (ADHD) were reviewed to determine if the WDI predicted the presence or severity of the disorders. The ages of the children ranged from 6 to 14. In two independent samples of children with LD (n=35 and n=26), the WDI did not predict LD status or severity. The LD samples were mostly male—85% and 57%, respectively. However, the WDI scores did significantly distinguish children with ADHD (n=10) from nondisabled children (n=10). The results were cross-validated on an independent sample of children with ADHD (n=17) when compared to non-ADHD children (n=22) who experienced significant behavioral difficulties. The ADHD samples were also mostly male—90% and 89%, respectively. The WDI classified only 59% of the children with ADHD and 86% of the non-ADHD children correctly. It is recommended that the WDI be considered a developmental index rather than a deterioration index in children. It is also recommended that significant WDI elevation ( 〉 .20) be considered to raise the question of ADHD, rather than simply yielding a diagnosis of ADHD.
    Type of Medium: Online Resource
    ISSN: 0022-2194 , 1538-4780
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1992
    detail.hit.zdb_id: 2077783-8
    SSG: 5,2
    SSG: 5,3
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  • 8
    Online Resource
    Online Resource
    SAGE Publications ; 2015
    In:  Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine Vol. 229, No. 1 ( 2015-01), p. 40-51
    In: Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, SAGE Publications, Vol. 229, No. 1 ( 2015-01), p. 40-51
    Abstract: Ankle–foot orthoses (AFOs) are prescribed for the management of gait-related problems. Prescription of AFOs is based on empirical techniques due to the low level of evidence-based research on their efficacy, but primarily poor understanding of their mechanical characteristics. This study aimed to establish a method that would allow the quantification of the contribution of AFOs in the control of the ankle joint during gait. A possible way of achieving this aim would be to measure strain on the AFO during walking by the use of strain gauges. Following successful experimentation with the application of strain gauges to polypropylene tensile specimens, an AFO was instrumented by attaching strain gauges to it so as to allow the moment generated on the AFO in the sagittal plane about the ankle to be measured. Walking trials using this AFO on an able-bodied subject indicated good step-to-step repeatability. The use of an instrumented AFO in conjunction with kinematic and kinetic data acquisition would allow the contribution of the AFO and the residual anatomical loads to be determined. The advantage of such procedure over previously reported ones resides on the use of the actual orthosis being worn by patients thereby conducting tests under real-life situations. It is believed that such analysis of the load actions of an orthosis, which may in future be carried out in three dimensions, would allow a better understanding of the interaction between the leg and the orthosis. This should ultimately enhance AFO prescription criteria and help in optimising patient/device matching.
    Type of Medium: Online Resource
    ISSN: 0954-4119 , 2041-3033
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2015
    detail.hit.zdb_id: 2032763-8
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