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  • 1
    Online Resource
    Online Resource
    “I Can’t Go Far”: Perceptions and Experiences of Heart Failure Patients Regarding Physical Activity: A Qualitative Study Using Semistructured Face-to-Face Interviews
    SAGE Publications ; 2022
    In:  Health Education & Behavior Vol. 49, No. 1 ( 2022-02), p. 78-86
    Details
    In: Health Education & Behavior, SAGE Publications, Vol. 49, No. 1 ( 2022-02), p. 78-86
    Abstract: Participation in regular physical activity (RPA) is beneficial to the quality of life and life expectancy of patients with chronic heart failure (CHF). However, it is inadequate in many patients. Aims To determine the factors that influence the practice of RPA in patients with CHF managed in general practice. Method This was a qualitative study using semistructured, individual face-to-face interviews. Patients with CHF (New York Heart Association Stages 1–3) capable of participating in RPA were enrolled by their general practitioner. A longitudinal and transversal inductive thematic analysis was performed by two researchers. Results Five themes emerged from the 19 interviews that were conducted. Poor knowledge of the disease and the benefits of participating in RPA, as well as the lack of motivation or enjoyment, in particular due to the absence of previous participation, were considered significant obstacles. Fear associated with CHF or other comorbidities was also an obstacle. Attendance at a rehabilitation center, family and social circles, and having a pet all appeared to be beneficial. Family and friends were important for motivating the patient to participate in an activity but could also be an obstacle when they were overprotective. Conclusion This study helps highlight the difficulties for patients with CHF associated with participation in RPA. Despite the obstacles, there are enabling factors on which the general practitioner may rely to motivate their patients.
    Type of Medium: Online Resource
    ISSN: 1090-1981 , 1552-6127
    URL: Article
    DOI: 10.1177/10901981211053247
    RVK:
    XA 10000
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2022
    detail.hit.zdb_id: 2082564-X
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  • 2
    Online Resource
    Online Resource
    Orthoptic Treatment of Convergence Insufficiency in Parkinson’s Disease: A Case Series
    SAGE Publications ; 2017
    In:  Gerontology and Geriatric Medicine Vol. 3 ( 2017-01-01), p. 233372141770373-
    Details
    In: Gerontology and Geriatric Medicine, SAGE Publications, Vol. 3 ( 2017-01-01), p. 233372141770373-
    Abstract: Introduction: This study reports a case series of orthoptic treatment (OT) for convergence insufficiency (CI) in individuals with Parkinson’s disease (PD). Method: We are reporting two cases of individuals with PD who completed OT for CI. Both had a confirmed diagnosis of CI, accompanied by CI-type symptomatology. They each underwent an OT program consisting of three office-based visits and 8 weeks of home-based exercises. Treatment outcome was based on the changes measured pre- versus post-OT on the near point of convergence, positive fusional vergences, and symptomatology score. Results: The two participants successfully completed therapy, gained ability to converge, had fewer symptoms, and were satisfied with the OT-induced changes they felt in their day-to-day lives. Conclusion: This case series show that OT for CI in PD is possible. Further research is required as these results demonstrate that OT has the potential to improve symptomatic CI in these patients. In the meantime, the positive results obtained in these two cases should encourage clinicians to consider OT (a therapy with no/minimal risk) for CI in patients with PD whose quality of life is affected by this binocular dysfunction.
    Type of Medium: Online Resource
    ISSN: 2333-7214 , 2333-7214
    URL: Article
    DOI: 10.1177/2333721417703735
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2844974-5
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  • 3
    Online Resource
    Online Resource
    Preservation of Cognitive Procedural Memory in a Case of Korsakoff's Syndrome: Methodological and Theoretical Insights
    SAGE Publications ; 1998
    In:  Perceptual and Motor Skills Vol. 86, No. 3_suppl ( 1998-06), p. 1267-1287
    Details
    In: Perceptual and Motor Skills, SAGE Publications, Vol. 86, No. 3_suppl ( 1998-06), p. 1267-1287
    Abstract: Using the Tower of Hanoï puzzle, Butters, et al. in 1985 illustrated the difficulties in learning the procedure and questioned the suitability of this task for the assessment of the cognitive procedural memory in Korsakoff's syndrome. Our objective, in the light of these criticisms, was to show preservation of cognitive procedural capacities with the Tower of Hanoï for a man (P.F.) who was suffering from alcoholic Korsakoff's syndrome. For this procedural task, some aids helped to compensate in part for the difficulties with declarative memory and with working memory. In this condition, P.F. was able to learn the cognitive procedure. This study suggests that cognitive procedural memory may be preserved in some patients suffering from Korsakoff's syndrome and that this may be shown when a suitable task is used The result makes it possible to discuss the interaction between declarative and procedural knowledge in the solving of the Tower of Hanoï.
    Type of Medium: Online Resource
    ISSN: 0031-5125 , 1558-688X
    URL: Article
    DOI: 10.2466/pms.1998.86.3c.1267
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1998
    detail.hit.zdb_id: 2066876-4
    SSG: 5,2
    SSG: 7,11
    SSG: 31
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  • 4
    Online Resource
    Online Resource
    Physical Structure and the Behavior of Senile Patients following Ward Remodeling
    SAGE Publications ; 1970
    In:  Aging and Human Development Vol. 1, No. 3 ( 1970-08), p. 231-239
    Details
    In: Aging and Human Development, SAGE Publications, Vol. 1, No. 3 ( 1970-08), p. 231-239
    Type of Medium: Online Resource
    ISSN: 0002-0974
    URL: Article
    DOI: 10.2190/AG.1.3.e
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1970
    detail.hit.zdb_id: 2067347-4
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  • 5
    Online Resource
    Online Resource
    Author's Reply
    SAGE Publications ; 1991
    In:  DICP Vol. 25, No. 7-8 ( 1991-07), p. 875-875
    Details
    In: DICP, SAGE Publications, Vol. 25, No. 7-8 ( 1991-07), p. 875-875
    Type of Medium: Online Resource
    ISSN: 1042-9611
    URL: Article
    DOI: 10.1177/106002809102500740
    Language: English
    Publisher: SAGE Publications
    Publication Date: 1991
    detail.hit.zdb_id: 2053518-1
    SSG: 15,3
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  • 6
    Online Resource
    Online Resource
    Incidence and Risk Factors in Concussion Events: A 5-Season Study in the French Top 14 Rugby Union Championship
    SAGE Publications ; 2021
    In:  The American Journal of Sports Medicine Vol. 49, No. 7 ( 2021-06), p. 1921-1928
    Details
    In: The American Journal of Sports Medicine, SAGE Publications, Vol. 49, No. 7 ( 2021-06), p. 1921-1928
    Abstract: Concussions are a source of major concern in rugby, and a limited number of studies have attempted to identify risk factors for these injuries. Purpose: To investigate the incidence of match concussion and associated risk factors, including individual workload, anthropometric variables, playing position, and season phase, in elite rugby union players. Study Design: Case-control study; Level of evidence 3. Methods: All concussions and explanatory variables were collected for every match over 5 consecutive seasons (2014-2018) in 1334 professional players participating in the French Top 14 championship. Concussion risk was estimated using mixed effects Poisson regression. Results: Mean match concussion incidence equated to 10.4 (95% CI, 9.3-11.5) concussions for 1000 hours of game exposure. A peak was reached in the 2016-2017 season (13.7; 95% CI, 11.0-16.5). A greater risk was observed in the playoffs as compared with the first phase of the season (incidence rate ratio, 3.96; 95% CI, 2.10-7.35). In comparison with other positions, half-backs incurred the highest rate of concussion events (incidence, 16.1; 95% CI, 11.8-20.3). Irrespective of playing position, those with greater height and lower body mass reported a higher risk of concussions ( P = .02), especially during tackling actions for lighter players ( P = .01) and during other match events for taller players ( P = .03). When adjusted for season phase, players who had accumulated a higher amount of playing time since the beginning of the season demonstrated a lower risk of concussion ( P = .005). Conclusion: Inter- and intraseasonal variations in concussion rates were observed. Within positional groups, lighter and taller players were more at risk, with the highest incidence generally observed in half-backs. Workload was measured by the number of matches played before a concussion event, and it appeared to have a protective rather than deleterious effect on concussion risk.
    Type of Medium: Online Resource
    ISSN: 0363-5465 , 1552-3365
    URL: Article
    DOI: 10.1177/03635465211006480
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2021
    detail.hit.zdb_id: 2063945-4
    SSG: 31
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  • 7
    Online Resource
    Online Resource
    Arterial Ultrasound Screening as a Tool for Coronary Risk Assessment in Asymptomatic Men and Women
    SAGE Publications ; 2012
    In:  Angiology Vol. 63, No. 4 ( 2012-05), p. 282-288
    Details
    In: Angiology, SAGE Publications, Vol. 63, No. 4 ( 2012-05), p. 282-288
    Abstract: One of the imaging tests most commonly used to assess cardiovascular diseases (CVDs) in daily practice is Doppler ultrasonography of the carotid and femoral arteries. We included 2709 participants with no history or symptoms of CVD; they had a risk factor assessment and a carotid and femoral ultrasonography at baseline. Incident cases of definite coronary events were recorded during a median follow-up of 6 years. Approximately, 63% of the sample presented abnormalities (carotid stenosis 〉 50%, carotid plaque, femoral plaque, increased intima–media thickness [IMT]). A moderately increased IMT ( 〉 0.63 mm) or the presence of carotid or femoral artery plaque was related to prognosis. The associations persisted after adjustment for pretest risk, treatment with statins, and other Doppler ultrasonography abnormalities. The hazard ratio increased significantly with the number of abnormalities (varying from 2.35 [1.16-4.74] to 14.83 [6.47-33.9]).
    Type of Medium: Online Resource
    ISSN: 0003-3197 , 1940-1574
    URL: Article
    DOI: 10.1177/0003319711414865
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2012
    detail.hit.zdb_id: 2065911-8
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  • 8
    Online Resource
    Online Resource
    Uveitis manifestations in patients of the Swiss Inflammatory Bowel Disease Cohort Study
    SAGE Publications ; 2019
    In:  Therapeutic Advances in Gastroenterology Vol. 12 ( 2019-01), p. 175628481986514-
    Details
    In: Therapeutic Advances in Gastroenterology, SAGE Publications, Vol. 12 ( 2019-01), p. 175628481986514-
    Abstract: The knowledge about risk factors for the onset of uveitis manifestations in patients with inflammatory bowel disease (IBD) is still limited. Here, we aimed to provide an overview of the clinical factors associated with the onset of uveitis in the Swiss IBD Cohort Study (SIBDCS). Methods: We included epidemiological and clinical data from 1840 patients with Crohn’s disease (CD) and 1426 patients with ulcerative colitis (UC) followed up in the SIBDCS between 2006 and 2018. Associations between disease characteristics and uveitis were assessed in univariate and multivariate analyses. Results: Overall, we identified 285 patients with uveitis. Uveitis was more frequent in patients with CD (11.1%; 205 of 1635) than UC (5.6%; 80 of 1346; odds ratio 2.11, p  〈  0.001). The occurrence of uveitis manifestations in patients with UC and CD was significantly associated with the onset of other extraintestinal manifestations, also in multivariate analyses. The onset of uveitis was associated with the hallmark features of severe disease in both CD and UC, including a higher clinical disease activity index and the use of immunomodulators or calcineurin inhibitors. In CD, uveitis was more frequent in females and showed a positive correlation with a positive family history of IBD. Conclusions: Our data demonstrate that uveitis in IBD occurs more often in CD as well as in women and is associated with a more severe disease course. This might guide physicians’ awareness in at-risk patients to the presence of uveitis extraintestinal manifestations and help to improve patient care.
    Type of Medium: Online Resource
    ISSN: 1756-2848 , 1756-2848
    URL: Article
    DOI: 10.1177/1756284819865142
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2019
    detail.hit.zdb_id: 2440710-0
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  • 9
    Online Resource
    Online Resource
    PD-L1-expression patterns in large-cell neuroendocrine carcinoma of the lung: potential implications for use of immunotherapy in these patients: the GFPC 03-2017 “EPNEC” study
    SAGE Publications ; 2020
    In:  Therapeutic Advances in Medical Oncology Vol. 12 ( 2020-01), p. 175883592093797-
    Details
    In: Therapeutic Advances in Medical Oncology, SAGE Publications, Vol. 12 ( 2020-01), p. 175883592093797-
    Abstract: Few data are available on programmed cell-death-protein-1–ligand-1 (PD-L1) expression on large-cell neuroendocrine carcinomas of the lung (LCNECs). We analyzed PD-L1 expression on tumor (TCs) and inflammatory cells (ICs) from LCNEC patients to assess relationships between this expression, clinical characteristics, and disease outcomes. Methods: PD-L1 expression was determined by immunohistochemistry with monoclonal antibody 22C3 in consecutive LCNEC patients managed in 17 French centers between January 2014 and December 2016. Results: After centralized review, only 68 out of 105 (64%) patients had confirmed LCNEC diagnoses. Median overall survival (OS) (95% CI) was 11 (7–16) months for all patients, 7 (5–10), 21 (10–not reached) and not reached months for metastatic, stage III and localized forms ( p = 0.0001). Respectively, 11% and 75% of the tumor samples were TC+ and IC+, and 66% had a TC–/IC+ profile. Comparing IC+ versus IC– metastatic LCNEC, the former had significantly longer progression-free survival [9 (4–13) versus 4 (1–8) months; p = 0.03], with a trend towards better median OS [12 (7–18) versus 9.5 (4–14) months; p = 0.21] . Compared to patients with TC– tumors, those with TC+ LCNECs tended to have non-significantly shorter median OS [4 (1–6.2) versus 11 (8–18) months, respectively]. Median OS was significantly shorter for patients with TC+/IC– metastatic LCNECs than those with TC–IC+ lesions (2 versus 8 months, respectively; p = 0.04). Conclusion: TC–/IC+ was the most frequent PD-L1–expression profile for LCNECs, a pattern quite specific compared with non-small-cell lung cancer and small-cell lung cancer. IC PD-L1 expression seems to have a prognostic role.
    Type of Medium: Online Resource
    ISSN: 1758-8359 , 1758-8359
    URL: Article
    DOI: 10.1177/1758835920937972
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2020
    detail.hit.zdb_id: 2503443-1
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  • 10
    Online Resource
    Online Resource
    Tool for Screening Visual Acuity in Older Individuals With Dementia
    SAGE Publications ; 2017
    In:  American Journal of Alzheimer's Disease & Other Dementiasr Vol. 32, No. 2 ( 2017-03), p. 96-100
    Details
    In: American Journal of Alzheimer's Disease & Other Dementiasr, SAGE Publications, Vol. 32, No. 2 ( 2017-03), p. 96-100
    Abstract: To develop a screening and referral algorithm tool to help identify which older institutionalized individuals with dementia need an eye examination. Methods: The visual acuity (VA) screening test was developed on an iPad retina display. Three optotypes were used (letters, numbers, and tumbling E’s) to determine whether one works best with dementia. The screening VA results and algorithm decision were validated against those obtained by an optometrist performing a complete eye examination. Results: Of the 150 participants, 14.7% did not respond to any optotype, while 85.3% responded to letters, 84.0% to numbers, and 66.0% to tumbling E’s. The VA achieved was superior for letters. The concordance for the screening versus eye examination was 〉 80% for VA and 90% for the algorithm. Conclusion: The results indicate that the tool was successful at identifying older individuals with dementia needing an eye examination.
    Type of Medium: Online Resource
    ISSN: 1533-3175 , 1938-2731
    URL: Article
    DOI: 10.1177/1533317517689877
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2017
    detail.hit.zdb_id: 2235173-5
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