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  • 1
    In: Obesity Facts, S. Karger AG, Vol. 4, No. 1 ( 2011), p. 61-66
    Type of Medium: Online Resource
    ISSN: 1662-4033 , 1662-4025
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2011
    detail.hit.zdb_id: 2455819-9
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  • 2
    In: Journal of Vascular Research, S. Karger AG, Vol. 53, No. 3-4 ( 2016), p. 121-127
    Abstract: 〈 b 〉 〈 i 〉 Aim: 〈 /i 〉 〈 /b 〉 To investigate whether an image acquisition stabilizer (IAS) mounted on the sidestream dark field camera (SDF) during gastrointestinal surgery improves image stability and acquisition. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 Serosal SDF imaging was compared with SDF imaging combined with an IAS (SDF + IAS) during gastrointestinal surgery. Stability was assessed as the image drift in pixels and the time to obtain stable images. The success rate was determined as the percentage of analyzable images after recording. The effect of negative pressure from the IAS was determined during single-spot measurements and by comparing microvascular parameters between groups. Data are presented as mean ± SD. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Sixty serosal measurements were performed per group; 87% were successful in the SDF group and 100% in the SDF + IAS group (p = 0.003). Image drift in the SDF group was 148 ± 36 versus 55 ± 15 pixels in the SDF + IAS group; p 〈 0.001. Time to stable image was 96 ± 60 s in the SDF group versus 57 ± 31 s in the SDF + IAS group; p = 0.03. No effect of negative pressure was seen. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 The use of an IAS mounted on an SDF camera during serosal microvascular assessment improves the success rate of image acquisition and stability and reduces the time to stable image with no effect on the microcirculation.
    Type of Medium: Online Resource
    ISSN: 1018-1172 , 1423-0135
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2016
    detail.hit.zdb_id: 1482726-8
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  • 3
    In: Digestive Surgery, S. Karger AG, Vol. 36, No. 2 ( 2019), p. 111-123
    Abstract: 〈 b 〉 〈 i 〉 Background: 〈 /i 〉 〈 /b 〉 This systematic review and meta-analysis evaluated the short- and long-term outcomes of liver resection for colorectal liver metastases (CRLM) in elderly patients. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 A PubMed, EMBASE, and Cochrane Library search was performed from January 1995 to April 2017, for studies comparing both short- and long-term outcomes in younger and elderly patients undergoing liver resection for CRLM. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Eleven studies comparing patients aged & #x3c;70 years with patients aged & #x3e;70 years and 4 studies comparing patients aged & #x3c;75 years with patients aged & #x3e;75 years were included. Postoperative morbidity was similar in patients aged & #x3e;70 years (27 vs. 30%; 〈 i 〉 p 〈 /i 〉  = 0.35) but higher in patients aged & #x3e;75 years (21 vs. 32%; 〈 i 〉 p 〈 /i 〉  = 0.001). Postoperative mortality was higher in both patients aged & #x3e;70 years (2 vs. 4%; 〈 i 〉 p 〈 /i 〉  = 0.01) and in patients aged & #x3e;75 years (1 vs. 6%; 〈 i 〉 p 〈 /i 〉  = 0.02). Mean 5-year overall survival was lower in patients aged & #x3e;70 years (40 vs. 32%; 〈 i 〉 p 〈 /i 〉   & #x3c; 0.001) but equal in patients aged & #x3e;75 years (42 vs. 32%; 〈 i 〉 p 〈 /i 〉  = 0.06). 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Although postoperative morbidity and mortality were increased with higher age, liver resection for CRLM seems justified in selected elderly patients.
    Type of Medium: Online Resource
    ISSN: 0253-4886 , 1421-9883
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2019
    detail.hit.zdb_id: 1468560-7
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  • 4
    In: Digestive Surgery, S. Karger AG, Vol. 34, No. 5 ( 2017), p. 371-379
    Abstract: 〈 b 〉 〈 i 〉 Background: 〈 /i 〉 〈 /b 〉 In the era of advanced surgical techniques and improved perioperative care, the willingness to perform emergency operations in elderly patients continues to increase. This systematic review aimed at assessing the clinical outcomes of early cholecystectomy in elderly patients with acute cholecystitis. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 Medline, Embase, and Cochrane Library databases were systematically searched for studies reporting on early cholecystectomy for acute cholecystitis in patients aged ≥70 years. The conversion rate, perioperative morbidity, and mortality were calculated using a random-effects model. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Eight articles fell within the scope of this study. In total, 592 patients were identified. The mean age was 81 years. Early cholecystectomy was performed laparoscopically in 316 patients (53%) and open in 276 patients (47%). The procedure was associated with a conversion rate of 23% (95% CI 18.6-28.3), a perioperative morbidity of 24% (95% CI 20.5-27.5), and a mortality of 3.5% (95% CI 2.3-5.4). 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Early cholecystectomy seems to be a feasible treatment in elderly patients with acute cholecystitis. To reduce morbidity, patients who may benefit from surgery ought to be selected carefully. Future prospective studies should compare early cholecystectomy with alternative treatments to select the treatment that is most appropriate for elderly patients.
    Type of Medium: Online Resource
    ISSN: 0253-4886 , 1421-9883
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2017
    detail.hit.zdb_id: 1468560-7
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