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  • 1
    In: Gynecologic and Obstetric Investigation, S. Karger AG, Vol. 76, No. 4 ( 2013), p. 241-247
    Abstract: 〈 b 〉 〈 i 〉 Background/Aims: 〈 /i 〉 〈 /b 〉 To evaluate the clinical and pathologic features of patients with mucinous borderline tumor (MBT) of the ovary with special emphasis on the endocervical-like (EMBT) and intestinal-type (IMBT). 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 This is a retrospective review of patients with MBT who were diagnosed and treated between 1995 and 2009 at a single institution. The records were analyzed for the patients' clinicopathologic information. The survival rates were calculated using the Kaplan-Meier method. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Of a total of 203 patients with MBT, there were 56 (27.6%) with EMBTs and 147 (72.4%) with IMBTs. Patients with EMBTs were significantly more asymptomatic (58.9%), had higher CA125 and CA19-9 levels, larger tumors (mean 17.3 cm), less frequent bilateral occurrence (5.4%), and less relation to endometriosis (1.4%), compared with those with IMBTs (all p 〈 0.05). During the median follow-up of 57.3 months (range 6-158), a total of 8 recurrences were identified: 6 were borderline and 2 were invasive lesion. With regard to the recurrence, EMBT and IMBT showed a 7-year recurrence-free survival rate of 97.1 and 92.1%, respectively, with no significant difference. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 EMBT and IMBT had different clinicopathological profiles, although the histologic distinction of MBT was not associated with the prognosis.
    Type of Medium: Online Resource
    ISSN: 0378-7346 , 1423-002X
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2013
    detail.hit.zdb_id: 1482695-1
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  • 2
    Online Resource
    Online Resource
    S. Karger AG ; 2013
    In:  Gynecologic and Obstetric Investigation Vol. 75, No. 1 ( 2013), p. 16-20
    In: Gynecologic and Obstetric Investigation, S. Karger AG, Vol. 75, No. 1 ( 2013), p. 16-20
    Abstract: 〈 b 〉 〈 i 〉 Background/Aims: 〈 /i 〉 〈 /b 〉 To evaluate the feasibility and safety of single-port access total laparoscopic hysterectomy (SPA-TLH) for large uterus ( 〉 500 g). 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 A prospective data collection was performed in 21 consecutive patients in March 2010 and August 2011. Surgical outcome including operative time (OT) and estimated blood loss (EBL) were analyzed. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 SPA-TLH procedures were successfully performed in 16 cases (76.2%). Of the 5 failed cases, 4 were converted to multiport TLH because of distorted uterine contours and pelvic adhesions and 1 was converted to laparotomy for bleeding control. The median OT, uterine weight, and EBL were 110 (65–165) min, 600 (502–980) g, and 200 (100–800) ml, respectively. Spearman’s correlation analysis demonstrated that OT and blood loss increased with increasing uterine weight (p = 0.003 and p = 0.033, respectively). No operative complications were observed during the hospital stay and 3-month follow-up following discharge. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 SPA-TLH for large uterus is a feasible and safe technique.
    Type of Medium: Online Resource
    ISSN: 0378-7346 , 1423-002X
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2013
    detail.hit.zdb_id: 1482695-1
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  • 3
    In: Gynecologic and Obstetric Investigation, S. Karger AG, Vol. 76, No. 1 ( 2013), p. 57-63
    Abstract: 〈 b 〉 〈 i 〉 Objective: 〈 /i 〉 〈 /b 〉 To compare the perioperative outcomes of three laparoscopic approaches for performing ovarian cyst enucleation. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 A total of 148 patients underwent laparoscopic cyst enucleation at the CHA Gangnam Medical Center between September 2010 and May 2011. We reviewed retrospectively the medical records including patient demographics, operative outcomes and complications. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 We assigned the 148 patients into three groups: single-port (group A: 40), 2-port (group B: 30) and 4-port (group C: 78). There were no statistically significant differences in patient characteristics. The operation times were 90.4 ± 43.6, 74.7 ± 22.0 and 63.8 ± 30.5 min, and the estimated blood loss was 179.3 ± 253.9, 73 ± 75.2 and 89.9 ± 106.7 ml, respectively. Mean operation time was longer (p 〈 0.001) and estimated blood loss was higher (p = 0.005) in group A than in the other groups. There was no statistical difference in perioperative complications among the three groups. In group A, additional port insertion rate was higher than in groups B and C (p 〈 0.001). 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Single-port surgery required longer operation time, had a higher estimated blood loss and used additional ports more frequently during the operation than the other groups. However, 2-port surgery had no significant differences from 4-port surgery in the surgical outcomes. Therefore, 2-port surgery can be an alternative surgical option for 4-port surgery in ovarian cyst enucleation.
    Type of Medium: Online Resource
    ISSN: 0378-7346 , 1423-002X
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2013
    detail.hit.zdb_id: 1482695-1
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  • 4
    Online Resource
    Online Resource
    S. Karger AG ; 2014
    In:  Gynecologic and Obstetric Investigation Vol. 78, No. 2 ( 2014), p. 81-87
    In: Gynecologic and Obstetric Investigation, S. Karger AG, Vol. 78, No. 2 ( 2014), p. 81-87
    Abstract: 〈 b 〉 〈 i 〉 Background/Aims: 〈 /i 〉 〈 /b 〉 To assess the feasibility, safety and patient satisfaction of laparoendoscopic single-site (LESS) surgery for extremely large ovarian cysts. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 We conducted a prospective study of LESS surgery among women with ovarian cysts with a minimum diameter ≥15 cm and with radiological and laboratory features suggestive of benign disease. The primary outcomes were perioperative complication rate, conversion rate and patient satisfaction. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 A total of 21 consecutive patients underwent the following LESS surgery over a period of 17 months: ovarian cystectomy (76%), adnexectomy (10%) and staging procedure (14%). Histological findings included benign (85%), borderline (10%) and malignant tumors (5%). Spillage occurred for 2 patients (10%). LESS surgery was successful without conversion in 20 patients (95%). There was 1 perioperative complication with subcutaneous hematoma (5%). The median operative time and estimated blood loss were 79.8 min (39-155) and 60 ml (10-180), respectively. Patients were highly satisfied with the results of LESS surgery, with a mean surgery satisfaction score of 9.4 ± 0.8 on a scale of 1-10. More than 71% of patients reported that the scar was invisible, and 95% said that they would recommend LESS surgery to others. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Based on our results, with proper patient selection, the size of an ovarian cyst does not necessarily constitute a contraindication for LESS surgery.
    Type of Medium: Online Resource
    ISSN: 0378-7346 , 1423-002X
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2014
    detail.hit.zdb_id: 1482695-1
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  • 5
    Online Resource
    Online Resource
    S. Karger AG ; 2017
    In:  Gynecologic and Obstetric Investigation Vol. 82, No. 5 ( 2017), p. 468-474
    In: Gynecologic and Obstetric Investigation, S. Karger AG, Vol. 82, No. 5 ( 2017), p. 468-474
    Abstract: 〈 b 〉 〈 i 〉 Objective: 〈 /i 〉 〈 /b 〉 To determine whether opportunistic salpingectomy in patients undergoing laparoscopic myomectomy has any deleterious effects on ovarian reserve and surgical risk. 〈 b 〉 〈 i 〉 Study Design: 〈 /i 〉 〈 /b 〉 We performed a retrospective review of patients who had no desire for future child bearing and who were undergoing laparoscopic myomectomy for symptomatic myomas at 4 institutions. Among them, 41 patients concurrently underwent opportunistic salpingectomy (the opportunistic salpingectomy group) and 65 patients did not undergo salpingectomy at the time of laparoscopic myomectomy (the no-salpingectomy group). The primary and secondary outcome measures were change of ovarian reserve determined by the rate of decline in the anti-Müllerian hormone (AMH) level from before surgery to 3 months post-surgery, and surgical outcomes. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Baseline characteristics were similar between groups. There were also no differences in surgical outcomes, such as operative time, operative bleeding, hospital stay, or complications between groups. The decline rate in AMH was 18.6% (interquartile range (IQR) 2.6-46.8%) in the opportunistic salpingectomy group and 10.4% (IQR 2.6-46.8%) in the no-salpingectomy group, with no significant difference between groups (p = 0.593). 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Opportunistic salpingectomy at the time of laparoscopic myomectomy was not associated with negative effects on ovarian reserve or increased surgical risk.
    Type of Medium: Online Resource
    ISSN: 0378-7346 , 1423-002X
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2017
    detail.hit.zdb_id: 1482695-1
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  • 6
    In: Gynecologic and Obstetric Investigation, S. Karger AG, Vol. 83, No. 1 ( 2018), p. 45-51
    Abstract: 〈 b 〉 〈 i 〉 Objectives: 〈 /i 〉 〈 /b 〉 To investigate whether elevated levels of CA125 (≥35 U/mL) and CA19-9 (≥37 U/mL) suggest advanced-stage disease (defined as stage II or higher) or poor prognosis in patients with borderline ovarian tumors (BOTs). 〈 b 〉 〈 i 〉 Study Design: 〈 /i 〉 〈 /b 〉 We retrospectively identified 591 patients with BOTs. Multivariate logistic regressions and Cox proportional hazard regressions were used to determine the clinicopathologic factors associated with the presence of advanced-stage disease and the prognostic factors associated with recurrence-free survival. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 CA125 was elevated more often in serous than in mucinous tumors (50.6 vs. 35.5%; 〈 i 〉 p 〈 /i 〉 = 0.003), whereas CA19-9 was elevated more often in mucinous than serous tumors (33.6 vs. 15.3%; 〈 i 〉 p 〈 /i 〉 = 0.001). An elevated CA125 level was independently associated with the presence of advanced-stage disease in serous ( 〈 i 〉 p 〈 /i 〉 = 0.005) and in mucinous BOTs ( 〈 i 〉 p 〈 /i 〉 = 0.015). However, preoperative elevation of CA19-9, unlike CA125, was not associated with the advanced-stage disease. Elevated preoperative CA125 level ( 〈 i 〉 p 〈 /i 〉 = 0.037) was an independent prognostic factor for recurrence-free survival in patients with serous BOTs. However, neither CA125 nor CA19-9 had prognostic significance in mucinous BOTs. 〈 b 〉 〈 i 〉 Conclusions: 〈 /i 〉 〈 /b 〉 Elevated preoperative CA125, unlike CA19-9, is a diagnostic and prognostic biomarker associated with the presence of advanced-stage disease and risk of relapse in patients with serous BOTs.
    Type of Medium: Online Resource
    ISSN: 0378-7346 , 1423-002X
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2018
    detail.hit.zdb_id: 1482695-1
    Location Call Number Limitation Availability
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