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  • 1
    Online Resource
    Online Resource
    S. Karger AG ; 2015
    In:  Oncology Research and Treatment Vol. 38, No. 6 ( 2015), p. 286-288
    In: Oncology Research and Treatment, S. Karger AG, Vol. 38, No. 6 ( 2015), p. 286-288
    Abstract: 〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 Over the past 3 decades, the appropriate management of metastatic germ cell tumours (GCT) has been defined by several phase III trials. Many follow-up recommendations have been published based on expert consensus. However, common clinical scenarios can still be vexing for clinicians who are less experienced at managing patients with testicular cancer. 〈 b 〉 〈 i 〉 Case Report: 〈 /i 〉 〈 /b 〉 We highlight the arduous diagnostic work-up of a suspected late relapsing metastatic GCT in a patient suffering from fatigue, weight loss and prominent retroperitoneal lymph nodes, 4 years after first-line chemotherapy for metastatic seminoma. The various explorations finally led to the diagnosis of Whipple's disease. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 This unusual clinical case strongly highlights the need to perform an exhaustive evaluation, with a biopsy, if a late recurrent GCT is suspected to avoid pointless and potentially harmful treatment.
    Type of Medium: Online Resource
    ISSN: 2296-5270 , 2296-5262
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2015
    detail.hit.zdb_id: 2749752-5
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  • 2
    Online Resource
    Online Resource
    S. Karger AG ; 1994
    In:  Dementia and Geriatric Cognitive Disorders Vol. 5, No. 6 ( 1994), p. 334-338
    In: Dementia and Geriatric Cognitive Disorders, S. Karger AG, Vol. 5, No. 6 ( 1994), p. 334-338
    Abstract: There is growing evidence that AD consists of different subtypes, and that language is a pertinent factor to identify a subgroup with a fast rate of cognitive decline. We report the first results of a longitudinal study in which we compared two groups of patients with probable AD. The main result showed that a subgroup with stable MMSE scores during a 1-year follow-up period had an impairment in language domains which are usually preserved until an advanced stage of the disease. It is proposed that this group may correspond to a variety of AD who, in addition to symptoms of AD, present characteristics of primary progressive aphasia. In other respects, we underscore that the high loading in language-mediated tasks of the MMSE makes it a poor index to accurately measure the rate of cognitive decline.
    Type of Medium: Online Resource
    ISSN: 1420-8008 , 1421-9824
    Language: English
    Publisher: S. Karger AG
    Publication Date: 1994
    detail.hit.zdb_id: 1482186-2
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