In:
Pathophysiology of Haemostasis and Thrombosis, S. Karger AG, Vol. 27, No. 3 ( 1997), p. 119-124
Abstract:
The techniques adopted for venipuncture and the mixing of aspirated blood with anticoagulant were evaluated for their possible contribution in pre-analytical variation in estimating plasma prothrombin fragment 1+2 (Fl+2), thrombin-antithrombin complex (TAT), soluble fibrin and total fibrin(ogen) degradation products. Antecubital vein blood samples were simultaneously collected in 20 subjects from either arm by technologists with high and less blood sampling experience employing a crossover design. Fl+2 and TAT were significantly higher in plasma obtained by a less experienced technologist. Three different mixing procedures of blood with anticoagulants did not influence the levels of the markers. The results emphasize that experienced technologists should preferably be selected for collecting blood for analysis of coagulation markers.
Type of Medium:
Online Resource
ISSN:
1424-8832
,
1424-8840
Language:
English
Publisher:
S. Karger AG
Publication Date:
1997
detail.hit.zdb_id:
2081182-2
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