In:
Psychotherapy and Psychosomatics, S. Karger AG, Vol. 92, No. 1 ( 2023), p. 38-48
Abstract:
〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 Major depressive disorder (MDD) is a highly prevalent and disabling disorder. This study examines two psychotherapy methods for MDD, behavioral activation (BA), and metacognitive therapy (MCT), when applied as outpatient treatments to severely affected patients. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 The study was conducted in a tertiary outpatient treatment center. Patients with a primary diagnosis of MDD ( 〈 i 〉 N 〈 /i 〉 = 122) were included in the intention-to-treat sample (55.7% female, mean age 41.9 years). Participants received one individual and one group session weekly for 6 months (M). Assessments took place at baseline, pretreatment, mid-treatment (3 M), post-treatment (6 M), and follow-up (12 M). The primary outcome was depressive symptomatology assessed by the Hamilton Rating Scale for Depression at 12 M follow-up. Secondary outcomes included general symptom severity, psychosocial functioning, and quality of life. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Linear mixed models indicated a change in depressive symptoms ( 〈 i 〉 F 〈 /i 〉 (2, 83.495) = 12.253, 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001) but no between-group effect ( 〈 i 〉 F 〈 /i 〉 (1, 97.352) = 0.183, 〈 i 〉 p 〈 /i 〉 = 0.670). Within-group effect sizes were medium for MCT (post-treatment: 〈 i 〉 d 〈 /i 〉 = 0.610; follow-up: 〈 i 〉 d 〈 /i 〉 = 0.692) and small to medium for BA (post-treatment: 〈 i 〉 d 〈 /i 〉 = 0.636, follow-up: 〈 i 〉 d 〈 /i 〉 = 0.326). In secondary outcomes, there were improvements ( 〈 i 〉 p 〈 /i 〉 ≤ 0.040) with medium to large within-group effect sizes ( 〈 i 〉 d 〈 /i 〉 ≥ 0.501) but no between-group effects ( 〈 i 〉 p 〈 /i 〉 ≥ 0.304). Response and remission rates did not differ between conditions at follow-up (response MCT: 12.9%, BA: 13.3%, remission MCT: 9.7%, BA: 10.0%). The deterioration rate was lower in MCT than in BA (χ 〈 sup 〉 2 〈 /sup 〉 〈 sub 〉 1 〈 /sub 〉 = 5.466, 〈 i 〉 p 〈 /i 〉 = 0.019, NTT = 7.4). 〈 b 〉 〈 i 〉 Discussion: 〈 /i 〉 〈 /b 〉 Both MCT and BA showed symptom reductions. Remission and response rates were lower than in previous studies, highlighting the need for further improvements in adapting/implementing treatments for severely affected patients with MDD.
Type of Medium:
Online Resource
ISSN:
0033-3190
,
1423-0348
Language:
English
Publisher:
S. Karger AG
Publication Date:
2023
detail.hit.zdb_id:
1472321-9
SSG:
5,2
SSG:
15,3
Permalink
