GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Online Resource
    Online Resource
    Isolation of Avian Nephroblastoma Virus from Avian Myeloblastosis Virus by the Infectious DNA Technique
    S. Karger AG ; 1974
    In:  Intervirology Vol. 4, No. 2 ( 1974), p. 69-76
    Details
    In: Intervirology, S. Karger AG, Vol. 4, No. 2 ( 1974), p. 69-76
    Type of Medium: Online Resource
    ISSN: 0300-5526 , 1423-0100
    URL: Article
    DOI: 10.1159/000149845
    RVK:
    XA 10000
    Language: English
    Publisher: S. Karger AG
    Publication Date: 1974
    detail.hit.zdb_id: 1482863-7
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    The Exploration of the Effectiveness of Group Therapy through an Internet Chat as Aftercare: A Controlled Naturalistic Study
    S. Karger AG ; 2007
    In:  Psychotherapy and Psychosomatics Vol. 76, No. 4 ( 2007), p. 219-225
    Details
    In: Psychotherapy and Psychosomatics, S. Karger AG, Vol. 76, No. 4 ( 2007), p. 219-225
    Abstract: 〈 i 〉 Background: 〈 /i 〉 Modern communication technologies offer novel opportunities for the provision of stepped care for patients with mental disorders. This study investigated the effectiveness of group therapy delivered through an Internet chat following inpatient treatment. The main goal of the program was to reduce the risk of losing the therapeutic benefits achieved during the preceding inpatient treatment. 〈 i 〉 Methods: 〈 /i 〉 114 patients participated in one of two parallel groups of 8–10 patients that met with a group therapist in an Internet chat room. The groups met weekly for 12–15 weeks for 90 min. Controls were 114 patients who did not participate in the chat groups and were matched by application of propensity score methods. The main criterion was derived from comprehensive assessments of changes in health status comprising the psychological and physical condition of the patients. Assessments were conducted at admission, discharge and 12 months after discharge. 〈 i 〉 Results: 〈 /i 〉 12 months after discharge, chat participants showed a substantially lower risk (24.7%) for negative outcome than controls (38.5%). Furthermore, the low dropout rate and the high session attendance supported the expectation that this novel offer met patients’ needs, and thus, opens a new avenue for the optimization of care for patients with mental disorders.
    Type of Medium: Online Resource
    ISSN: 0033-3190 , 1423-0348
    URL: Article
    DOI: 10.1159/000101500
    RVK:
    CU 5500
    RVK:
    XA 10000
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2007
    detail.hit.zdb_id: 1472321-9
    SSG: 5,2
    SSG: 15,3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Mehrfach rezidivierende, bakterielle otogene Meningitis nach Felsenbeinquerbruch
    S. Karger AG ; 1958
    In:  ORL Vol. 20, No. 1 ( 1958), p. 18-28
    Details
    In: ORL, S. Karger AG, Vol. 20, No. 1 ( 1958), p. 18-28
    Type of Medium: Online Resource
    ISSN: 0301-1569 , 1423-0275
    URL: Article
    DOI: 10.1159/000274121
    Language: English
    Publisher: S. Karger AG
    Publication Date: 1958
    detail.hit.zdb_id: 1483533-2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Hepatopathie und Magen-Darmkrankheiten
    S. Karger AG ; 1953
    In:  Digestion Vol. 79, No. 1 ( 1953), p. 1-16
    Details
    In: Digestion, S. Karger AG, Vol. 79, No. 1 ( 1953), p. 1-16
    Type of Medium: Online Resource
    ISSN: 0012-2823 , 1421-9867
    URL: Article
    DOI: 10.1159/000199741
    RVK:
    XA 40650
    RVK:
    XA 10000
    Language: English
    Publisher: S. Karger AG
    Publication Date: 1953
    detail.hit.zdb_id: 1482218-0
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    SMS-Nachsorge: Sektorenübergreifende Versorgung für Patientinnen mit Bulimia nervosa
    S. Karger AG ; 2013
    In:  Verhaltenstherapie Vol. 23, No. 3 ( 2013), p. 204-209
    Details
    In: Verhaltenstherapie, S. Karger AG, Vol. 23, No. 3 ( 2013), p. 204-209
    Abstract: 〈 b 〉 〈 i 〉 Hintergrund: 〈 /i 〉 〈 /b 〉 Über den Zusammenhang zwischen der Teilnahme an E-Mental-Health-Interventionen und der Inanspruchnahme regulärer Psychotherapie ist bisher wenig bekannt. In der vorliegenden Studie wurde untersucht, inwiefern ein SMS-basiertes Nachsorgeprogramm mit einem veränderten Inanspruchnahmeverhalten ambulanter Therapie im Anschluss an eine stationäre Behandlung für Essstörungen assoziiert ist. 〈 b 〉 〈 i 〉 Methode: 〈 /i 〉 〈 /b 〉 165 Patientinnen, die aufgrund einer vollausgeprägten oder subsyndromalen Bulimia nervosa stationär behandelt wurden, wurden randomisiert jeweils einer Kontrollgruppe (KG: treatment as ususal (TAU)) oder Interventionsgruppe (IG: 16-wöchige Nachsorge über SMS zusätzlich zu TAU) zugewiesen. Erfasst wurden die Rückfallrate und die Inanspruchnahme ambulanter Therapie innerhalb des 8-monatigen Follow-up-Zeitraums. 〈 b 〉 〈 i 〉 Ergebnisse: 〈 /i 〉 〈 /b 〉 In der KG wurden signifikant mehr Rückfälle beobachtet als in der IG (KG: 42,0%; IG: 26,8%). Vergleichbar viele Teilnehmerinnen nahmen ambulante Therapie in Anspruch (KG: 52,2%; IG: 53,5%). Innerhalb der Teilnehmerinnen, die eine ambulante Therapie aufnahmen, unterschieden sich die Rückfallraten von KG und IG nicht signifikant (KG: 38,9%; IG: 28,9%). Ein bedeutsamer Unterschied wurde hingegen in der Untergruppe festgestellt, die keine ambulante Therapie nutzte (KG: 45,5%; IG: 24,2%). 〈 b 〉 〈 i 〉 Schlussfolgerung: 〈 /i 〉 〈 /b 〉 Die Studie unterstreicht den Bedarf an sektorenübergreifenden Versorgungsangeboten (stationär-ambulant). Die Studie liefert erste Hinweise, dass das SMS-Programm das Inanspruchnahmeverhalten bezüglich ambulanter Therapie positiv beeinflussen könnte. Weitere Studien sind notwendig, um diesen möglichen kausalen Effekt zu untersuchen.
    Type of Medium: Online Resource
    ISSN: 1016-6262 , 1423-0402
    URL: Article
    DOI: 10.1159/000354660
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2013
    detail.hit.zdb_id: 1483583-6
    SSG: 5,2
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Human Acellular Dermal Matrix (Epiflex®) in Immediate Implant-Based Breast Reconstruction after Skin- and Nipple-Sparing Mastectomy and Treatment of Capsular Fibrosis: Results of a Multicenter, Prospective, Observational NOGGO-AWOGyn Study
    S. Karger AG ; 2021
    In:  Breast Care Vol. 16, No. 5 ( 2021), p. 461-467
    Details
    In: Breast Care, S. Karger AG, Vol. 16, No. 5 ( 2021), p. 461-467
    Abstract: 〈 b 〉 〈 i 〉 Background: 〈 /i 〉 〈 /b 〉 Over the last decades, the number of acellular dermal matrix (ADM)-assisted implant-based breast reconstructions (IBBR) has substantially increased. However, there is still a lack of prospective data on complication rates. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 We performed a non-interventional, multicenter, prospective cohort study to evaluate complication rates of a human ADM in patients undergoing an IBBR after skin- and nipple-sparing mastectomies. Patients with primary reconstruction (cohort A) and patients undergoing a secondary reconstruction after capsular fibrosis (cohort B) using the human ADM Epiflex® (DIZG gGmbH, Berlin, Germany) were enrolled in this study. Patients were followed-up for 12 months after surgery. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Eighty-four eligible patients were included in this study of whom 28 women underwent a bilateral breast reconstruction, leading to 112 human ADM-assisted reconstructions in total (cohort A: 73, cohort B: 39). In 33.0% of the reconstructed breasts at least one of the complications of primary interest occurred, including implant loss 7.1%, seroma 15.2%; infection 5.4%, rash 8.0%, and Baker grade III/IV capsular fibrosis 2.7%, with no statistically significant differences between the cohorts. Previous radiation therapy was significantly associated with occurrence of any postoperative complication (OR 20.41; 〈 i 〉 p 〈 /i 〉 value 0.027). 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 The rates of most complications were comparable to the rates reported for other ADMs with relatively low rates of capsular fibrosis and infections. The rate of seroma was increased in our study. Prior radiation therapy increased the risk of any postoperative complications. Therefore, the use of ADM in these patients should be considered carefully.
    Type of Medium: Online Resource
    ISSN: 1661-3791 , 1661-3805
    URL: Article
    DOI: 10.1159/000512201
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2021
    detail.hit.zdb_id: 2205941-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Metabolomics in Sepsis and Its Impact on Public Health
    S. Karger AG ; 2017
    In:  Public Health Genomics Vol. 20, No. 5 ( 2017), p. 274-285
    Details
    In: Public Health Genomics, S. Karger AG, Vol. 20, No. 5 ( 2017), p. 274-285
    Abstract: Sepsis, with its often devastating consequences for patients and their families, remains a major public health concern that poses an increasing financial burden. Early resuscitation together with the elucidation of the biological pathways and pathophysiological mechanisms with the use of “-omics” technologies have started changing the clinical and research landscape in sepsis. Metabolomics (i.e., the study of the metabolome), an “-omics” technology further down in the “-omics” cascade between the genome and the phenome, could be particularly fruitful in sepsis research with the potential to alter the clinical practice. Apart from its benefit for the individual patient, metabolomics has an impact on public health that extends beyond its applications in medicine. In this review, we present recent developments in metabolomics research in sepsis, with a focus on pneumonia, and we discuss the impact of metabolomics on public health, with a focus on free/libre open source software.
    Type of Medium: Online Resource
    ISSN: 1662-4246 , 1662-8063
    URL: Article
    DOI: 10.1159/000486362
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2017
    detail.hit.zdb_id: 2457026-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    Radiological Findings, Pulmonary Function and Dyspnea in Underground Coal Miners
    S. Karger AG ; 2007
    In:  Respiration Vol. 74, No. 1 ( 2007), p. 80-87
    Details
    In: Respiration, S. Karger AG, Vol. 74, No. 1 ( 2007), p. 80-87
    Abstract: 〈 i 〉 Background: 〈 /i 〉 Respiratory disability induced by dust exposure in coal workers is assessed by pulmonary function tests and radiological evidence of pneumoconiosis. High-resolution computed tomography (HR-CT) improves the visibility of tissue changes, but the value of the findings for the clinical evaluation is controversial. 〈 i 〉 Objectives: 〈 /i 〉 It was the aim of this study to evaluate the correlation between the International Labour Office (ILO) classification and the degree of emphysema in HR-CT with self-reported dyspnea and pulmonary function tests including diffusion capacity for CO (D 〈 sub 〉 L,CO 〈 /sub 〉 ). 〈 i 〉 Methods: 〈 /i 〉 We investigated 87 coal miners (aged 67 ± 6 years), having worked underground for 26 ± 9 years, with pulmonary function tests and HR-CT. Univariate associations were tested with correlation coefficients, and multivariable analyses used a stepwise forward regression model. 〈 i 〉 Results: 〈 /i 〉 No aspect of the ILO classification showed a univariate correlation with dyspnea or forced expiratory flow in 1 s (FEV 〈 sub 〉 1 〈 /sub 〉 ). Emphysema CT score was strongly associated with D 〈 sub 〉 L,CO 〈 /sub 〉 (r 〈 sub 〉 s 〈 /sub 〉 = –0.40; p 〈 0.001) and FEV 〈 sub 〉 1 〈 /sub 〉 /maximal vital capacity (r = –0.38; p 〈 0.001) in univariate analysis, but not with the clinical grade of dyspnea (r = –0.14; p = 0.256). CT emphysema score but not ILO classification was associated with FEV 〈 sub 〉 1 〈 /sub 〉 in multivariable analyses (r 〈 sub 〉 s 〈 /sub 〉 = –0.37; p 〈 0.001). Dyspnea was best approximated by D 〈 sub 〉 L,CO 〈 /sub 〉 (r = –0.312; p = 0.008). 〈 i 〉 Conclusion: 〈 /i 〉 The clinical grade of breathlessness was best approximated by D 〈 sub 〉 L,CO 〈 /sub 〉 . HR-CT showed a good association with expiratory flow limitation. ILO classification of the chest radiograph may be a marker of exposure but conveys little information about the degree of respiratory impairment.
    Type of Medium: Online Resource
    ISSN: 0025-7931 , 1423-0356
    URL: Article
    DOI: 10.1159/000090200
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2007
    detail.hit.zdb_id: 1464419-8
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Digoxin-Like Immunoreactive Substance in Nonoliguric Hyperkalemia of the Premature Infant
    S. Karger AG ; 2003
    In:  Neonatology Vol. 83, No. 3 ( 2003), p. 182-187
    Details
    In: Neonatology, S. Karger AG, Vol. 83, No. 3 ( 2003), p. 182-187
    Abstract: Nonoliguric hyperkalemia of premature infants probably results from a transient inhibition of membrane-bound Na 〈 sup 〉 + 〈 /sup 〉 /K 〈 sup 〉 + 〈 /sup 〉 -ATPase during the first 24 h after birth. We hypothesized that the endogenous digitalis-like activity of the serum of premature infants, which inhibits the Na 〈 sup 〉 + 〈 /sup 〉 /K 〈 sup 〉 + 〈 /sup 〉 -ATPase, triggered hyperkalemia. Serum concentrations of potassium ([K 〈 sup 〉 + 〈 /sup 〉 ]) and of the digoxin-like immunoreactive substance ([DLIS] ) were measured during the first 24 h after birth in 60 infants including 30 infants 〈 30 gestational weeks. Contrary to our hypothesis, there was a negative linear correlation between [DLIS] at birth and [K 〈 sup 〉 + 〈 /sup 〉 ] 24 h after birth (r 〈 sup 〉 2 〈 /sup 〉 = 0.24, p 〈 0.002). 24 h after birth there was no correlation between [DLIS] and [K 〈 sup 〉 + 〈 /sup 〉 ]. Thus, a major role of DLIS in nonoliguric hyperkalemia could not be established.
    Type of Medium: Online Resource
    ISSN: 1661-7800 , 1661-7819
    URL: Article
    DOI: 10.1159/000068929
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2003
    detail.hit.zdb_id: 2403535-X
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Early Mood Swings as Symptoms of the Bipolar Prodrome: Preliminary Results of a Retrospective Analysis
    S. Karger AG ; 2009
    In:  Psychopathology Vol. 42, No. 5 ( 2009), p. 337-342
    Details
    In: Psychopathology, S. Karger AG, Vol. 42, No. 5 ( 2009), p. 337-342
    Abstract: 〈 i 〉 Background/Aims: 〈 /i 〉 Temperament and mood swings are promising indicators for the characterization of mood spectrum vulnerability. The aim of this study was to investigate the relationship between affective temperament and mood swings in bipolar disorder. We explored these clinical features retrospectively. 〈 i 〉 Methods: 〈 /i 〉 Patients who met the criteria for bipolar I disorder were enrolled in the study. Exclusion criteria were partial remittance and a full affective or psychotic episode. Data concerning illness and family history, mood swings (semistructured interview for mood swings) and depression (Beck, Depression Inventory) were obtained. We examined premorbid temperament with the validated German version Temps-M of the original version Temps-A. Patients with and without mood swings were compared with respect to the dominant temperament. 〈 i 〉 Results: 〈 /i 〉 Out of 20 bipolar patients, 6 subjects reported mood swings prior to the onset of affective disorder. Subjects with mood swings prior to the onset of bipolar disorder significantly correlated with a positive family history of affective disorders. Concerning cyclothymic and irritable temperament, bipolar affective patients with mood swings had higher scores. No differences were found between males and females. 〈 i 〉 Conclusion: 〈 /i 〉 Our findings go in line with previous results that mood swings, as represented by the cyclothymic temperament, are present prior to the first onset of bipolar disorder in a subset of patients. These traits may represent vulnerability markers and could presumably be used to identify individuals at high risk for developing bipolar disorder in order to prevent this illness. Further studies are indicated to clarify the correlation with genetic risk factors.
    Type of Medium: Online Resource
    ISSN: 0254-4962 , 1423-033X
    URL: Article
    DOI: 10.1159/000232977
    RVK:
    XA 10000
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2009
    detail.hit.zdb_id: 1483565-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...