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  • S. Karger AG  (4)
  • Medicine  (4)
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  • S. Karger AG  (4)
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  • Medicine  (4)
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  • 1
    In: Ophthalmic Research, S. Karger AG
    Abstract: 〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 The aim of the study was to assess changes in choroidal thickness (ChT) after administration of 1% atropine for 1 week in myopic, emmetropic, and hyperopic children. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 A total of 235 children aged 4–8 years, which included 46 myopia, 34 emmetropia, and 155 hyperopia patients, were recruited and divided into three groups according to the spherical equivalent with the use of 1% atropine twice a day for 1 week. The ChT was measured at baseline and 1 week. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 In the myopia and emmetropia groups, following administration of 1% atropine gel, the ChT thickened significantly under the fovea (i.e., from 278.29 ± 53.01 μm to 308.24 ± 57.3 μm, 〈 i 〉 p 〈 /i 〉 & #x3c; 0.05; from 336.10 ± 78.60 μm to 353.46 ± 70.22 μm, 〈 i 〉 p 〈 /i 〉 & #x3c; 0.05, respectively), and at all intervals from the fovea, while in the hyperopia group, there was no significant difference in the ChT except the nasal side ( 〈 i 〉 p 〈 /i 〉 & #x3c; 0.05). 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Topical administration of 1% atropine gel for 1 week significantly increased the subfoveal and parafoveal ChT in children with myopia and emmetropia. Atropine did not increase the ChT in hyperopic children, except on the nasal side.
    Type of Medium: Online Resource
    ISSN: 0030-3747 , 1423-0259
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2023
    detail.hit.zdb_id: 1483177-6
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  • 2
    In: International Archives of Allergy and Immunology, S. Karger AG, Vol. 184, No. 6 ( 2023), p. 529-538
    Abstract: Since the global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a symptom of the onset of SARS-CoV-2, olfactory dysfunction (OD), has attracted tremendous attention. OD is not only a negative factor for quality of life but also an independent hazard and early biomarker for various diseases, such as Parkinson’s and Huntington’s diseases. Therefore, early identification and treatment of OD in patients are critical. Many etiological factors are responsible for OD based on current opinions. Sniffin’Sticks are recommended to identify the initial position (central or peripheral) for OD when treating patients clinically. It is worth emphasizing that the olfactory region in nasal cavity is recognized as the primary and critical olfactory receptor. Many nasal diseases, such as those with traumatic, obstructive and inflammatory causes, can lead to OD. The key question is no refined diagnosis or treatment strategy for nasogenic OD currently. This study summarizes the differences in medical history, symptoms, auxiliary examination, treatment and prognosis of different types of nasogenic OD by analyzing the current studies. We propose using olfactory training after 4–6 weeks of initial treatment for nasogenic OD patients with no significant improvement in olfaction. We hope that our research can provide valuable clinical guidance by systematically summarizing the clinical characteristics of nasogenic OD.
    Type of Medium: Online Resource
    ISSN: 1018-2438 , 1423-0097
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2023
    detail.hit.zdb_id: 1482722-0
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  • 3
    Online Resource
    Online Resource
    S. Karger AG ; 2012
    In:  Ophthalmologica Vol. 227, No. 4 ( 2012), p. 215-222
    In: Ophthalmologica, S. Karger AG, Vol. 227, No. 4 ( 2012), p. 215-222
    Abstract: 〈 b 〉 〈 i 〉 Aims: 〈 /i 〉 〈 /b 〉 To evaluate anterior segment optical coherence tomography (AS-OCT) in the diagnosis and treatment of Descemet’s membrane detachment (DMD) with severe corneal edema. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 Nine eyes of 7 consecutive patients with suspected DMD with severe corneal edema due to different causes were imaged with the AS-OCT system. Configuration of Descemet’s membrane (DM) was delineated before and after treatment, and quantitative analysis was performed. An appropriate treatment was chosen based on the imaging findings. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 DMD was demonstrated as being present in all eyes via AS-OCT. Different statuses of the DM including planar/nonplanar detachment, local/extensive detachment, and rupture was documented using AS-OCT images. Two eyes were treated with conservative therapy, 6 eyes with intracameral air/gas tamponade and 1 eye with penetrating keratoplasty. One of the air tamponade treatments failed and all the other treatments were successful. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 AS-OCT is a valuable tool in the diagnosis of DMD both in terms of selecting the appropriate treatment, and monitoring treatment outcomes when corneal edema is present.
    Type of Medium: Online Resource
    ISSN: 0030-3755 , 1423-0267
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2012
    detail.hit.zdb_id: 1483531-9
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  • 4
    In: Ophthalmic Research, S. Karger AG, Vol. 66, No. 1 ( 2023), p. 27-38
    Abstract: 〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 Myopia is an increasingly serious health problem in China. The aim of this study was to investigate the prevalence of myopia and the factors associated with it among students in Nantong, China, to show the current status of myopia prevention. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 This school-based, cross-sectional study examined students from all high schools in an urban area of Nantong, China. At least two classes were randomly selected from each grade of each school. A self-reported questionnaire was used to collect the required information. Univariate analyses were performed to identify associations between myopia and various parameters. Noncycloplegic autorefraction and visual acuity were assessed for each student. Factors that were statistically significant in univariate analyses were selected for multivariate analyses. Myopia was defined as a spherical equivalent refraction of ≤−0.5 diopters. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 The completion percentage of students out of the whole high school was 6.5%. The overall prevalence of myopia was 94%. The response percentage of the number of validated questionnaires was 90.2%, of which 50.2% ( 〈 i 〉 n 〈 /i 〉 = 1,466) were from male participants, and 49.8% ( 〈 i 〉 n 〈 /i 〉 = 1,452) were from female participants. The mean (SD) of age was 15.22 ± 1.75 years, ranging from 12 to 18 years. Factors such as female sex, older age, parental myopia, sitting in the back of the classroom, increased homework time, and minimal outdoor activity were significantly associated with a higher risk of myopia ( 〈 i 〉 p 〈 /i 〉 & #x3c; 0.05). In the myopic population, most students (67.9%) did not take measures to prevent further progression of myopia. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 The prevalence of myopia among high school students was 94%. Female sex, older age, parental myopia, sitting in the back of the classroom, increased homework time, and minimal outdoor activity were significantly associated with a higher risk of myopia. Most students with myopia (67.9%) did not take measures to prevent further progression of myopia.
    Type of Medium: Online Resource
    ISSN: 0030-3747 , 1423-0259
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2023
    detail.hit.zdb_id: 1483177-6
    Location Call Number Limitation Availability
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