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  • S. Karger AG  (2)
  • Comparative Studies. Non-European Languages/Literatures  (2)
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  • S. Karger AG  (2)
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  • Comparative Studies. Non-European Languages/Literatures  (2)
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  • 1
    In: Folia Phoniatrica et Logopaedica, S. Karger AG, Vol. 75, No. 1 ( 2023), p. 23-34
    Abstract: 〈 b 〉 〈 i 〉 Purpose: 〈 /i 〉 〈 /b 〉 The goal of this study was to examine the efficacy of acceleration-based articulatory measures in characterizing the decline in speech motor control due to amyotrophic lateral sclerosis (ALS). 〈 b 〉 〈 i 〉 Method: 〈 /i 〉 〈 /b 〉 Electromagnetic articulography was used to record tongue and lip movements during the production of 20 phrases. Data were collected from 50 individuals diagnosed with ALS. Articulatory kinematic variability was measured using the spatiotemporal index of both instantaneous acceleration and speed signals. Linear regression models were used to analyze the relationship between variability measures and intelligible speaking rate (a clinical measure of disease progression). A machine learning algorithm (support vector regression, SVR) was used to assess whether acceleration or speed features (e.g., mean, median, maximum) showed better performance at predicting speech severity in patients with ALS. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 As intelligible speaking rate declined, the variability of acceleration of tongue and lip movement patterns significantly increased ( 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001). The variability of speed and vertical displacement did not significantly predict speech performance measures. Additionally, based on 〈 i 〉 R 〈 /i 〉 〈 sup 〉 2 〈 /sup 〉 and root mean square error (RMSE) values, the SVR model was able to predict speech severity more accurately from acceleration features ( 〈 i 〉 R 〈 /i 〉 〈 sup 〉 2 〈 /sup 〉 = 0.601, RMSE = 38.453) and displacement features ( 〈 i 〉 R 〈 /i 〉 〈 sup 〉 2 〈 /sup 〉 = 0.218, RMSE = 52.700) than from speed features ( 〈 i 〉 R 〈 /i 〉 〈 sup 〉 2 〈 /sup 〉 = 0.554, RMSE = 40.772). 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Results from these models highlight differences in speech motor control in participants with ALS. The variability in acceleration of tongue and lip movements increases as speech performance declines, potentially reflecting physiological deviations due to the progression of ALS. Our findings suggest that acceleration is a more sensitive indicator of speech deterioration due to ALS than displacement and speed and may contribute to improved algorithm designs for monitoring disease progression from speech signals.
    Type of Medium: Online Resource
    ISSN: 1021-7762 , 1421-9972
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2023
    detail.hit.zdb_id: 1482295-7
    SSG: 7,11
    Location Call Number Limitation Availability
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  • 2
    Online Resource
    Online Resource
    S. Karger AG ; 2012
    In:  Folia Phoniatrica et Logopaedica Vol. 64, No. 2 ( 2012), p. 94-102
    In: Folia Phoniatrica et Logopaedica, S. Karger AG, Vol. 64, No. 2 ( 2012), p. 94-102
    Abstract: 〈 b 〉 〈 i 〉 Objective: 〈 /i 〉 〈 /b 〉 The relations between acoustic measures and their articulatory bases have rarely been tested in dysarthria but are important for diagnostic and treatment purposes. We tested the association between acoustic measures of F2 range and F2 slope with kinematic measures of tongue movement displacement and speed in individuals with amyotrophic lateral sclerosis (ALS) and healthy controls speaking at normal and slow rates. Relations between acoustic and kinematic measures and speech intelligibility were examined. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 As healthy controls reduced their speaking rate, their F2 slopes and movement speeds decreased. In talkers with ALS, acoustic and kinematic variables were associated with changes in speaking rate, characteristic of disease progression. Participants with slow rate had shallower F2 slopes and slower movement speeds than those with normal rate. Relations between F2 range and tongue displacement were weaker. F2 slope, displacement, and duration were correlated with speech intelligibility most consistently. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Findings suggested that F2 slope is a useful marker for tracking disease progression in ALS. F2 slope reflects changes in tongue function with disease progression and is linked to speech intelligibility. Changes in movement speed, however, might be the earliest sign of disease in the tongue.
    Type of Medium: Online Resource
    ISSN: 1021-7762 , 1421-9972
    RVK:
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2012
    detail.hit.zdb_id: 1482295-7
    SSG: 7,11
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
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