Publication Date:
2011-03-29
Description:
The X-ray crystal structure of CD38/Compound4 complex and computer simulation of Compound7 docking to CD38 show the significant role of nicotinamide for the substrate recognization of CD38 and the effect of aromatic group at the end of the chain. Min Dong, Yuan-Qi Si, Shuang-Yong Sun, Xiao-Ping Pu, Zhen-Jun Yang, Liang-Ren Zhang, Li-He Zhang, Fung Ping Leung, Connie Mo Ching. Lam, Anna Ka Yee Kwong, Jianbo Yue, Yeyun Zhou, Irina A. Kriksunov, Quan Hao, Hon Cheung Lee ( from Org. Biomol. Chem.) Min Dong, Org. Biomol. Chem., 2011, DOI: 10.1039/C0OB00768D To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Print ISSN:
1477-0520
Electronic ISSN:
1477-0539
Topics:
Chemistry and Pharmacology
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