In:
Chemical Science, Royal Society of Chemistry (RSC), Vol. 13, No. 30 ( 2022), p. 8834-8839
Kurzfassung:
An organocatalytic enantioselective radical reaction of potassium alkyltrifluoroborates, DABCO·(SO 2 ) 2 and α,β-unsaturated carbonyl compounds under photoinduced conditions is developed, which provides an efficient pathway for the synthesis of chiral β-sulfonyl carbonyl compounds in good yields with excellent enantioselectivity (up to 96% ee). Aside from α,β-unsaturated carbonyl compounds with auxiliary groups, common chalcone substrates are also well compatible with this organocatalytic system. This method proceeds through an organocatalytic enantioselective radical sulfonylation under photoinduced conditions, and represents a rare example of asymmetric transformation involving sulfur dioxide insertion.
Materialart:
Online-Ressource
ISSN:
2041-6520
,
2041-6539
Sprache:
Englisch
Verlag:
Royal Society of Chemistry (RSC)
Publikationsdatum:
2022
ZDB Id:
2559110-1
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