In:
RSC Advances, Royal Society of Chemistry (RSC), Vol. 13, No. 35 ( 2023), p. 24445-24449
Abstract:
Metal-free halogenated anhydrides promote the intramolecular cyclization of N -cyano sulfoximines. Trifluoro- or trichloroacetic anhydride (TFAA or TCAA, respectively) activate the N -cyano groups of N -cyano sulfoximines, leading to the intramolecular cyclization of 2-benzamide- N -cyano sulfoximines 1. This method results in excellent yields of thiadiazinone 1-oxides 2. A full intramolecular cyclization pattern was suggested by (i) labeling experiments with 13 C, (ii) isolating of N -trifluoroacetyl sulfoximine 1ac, and (iii) confirming the generation of the intermediate 1ad by LC/MS analysis.
Type of Medium:
Online Resource
ISSN:
2046-2069
Language:
English
Publisher:
Royal Society of Chemistry (RSC)
Publication Date:
2023
detail.hit.zdb_id:
2623224-8
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