In:
Organic & Biomolecular Chemistry, Royal Society of Chemistry (RSC), Vol. 21, No. 16 ( 2023), p. 3317-3322
Abstract:
A variety of azaheterocycle-fused piperidines and pyrrolidines bearing CF 3 and CHF 2 functionalities were obtained using CF 3 SO 2 Na and CHF 2 SO 2 Na by visible light photocatalysis. This protocol involves a radical cascade cyclization via tandem tri- and difluoromethylation–arylation of pendent unactivated alkenes. Benzimidazole, imidazole, theophylline, purine, and indole serve as applicable anchors, thereby enriching the structural diversity of piperidine and pyrrolidine derivatives. This method features mild, additive-free and transition metal-free conditions.
Type of Medium:
Online Resource
ISSN:
1477-0520
,
1477-0539
Language:
English
Publisher:
Royal Society of Chemistry (RSC)
Publication Date:
2023
detail.hit.zdb_id:
2097583-1
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