In:
The Journal of General Physiology, Rockefeller University Press, Vol. 48, No. 5 ( 1965-05-01), p. 933-948
Abstract:
The exchange of cell K with K42, JK, has been measured in cat right ventricular papillary muscle under conditions of a steady state with respect to intracellular K concentration. Within the limits of the measurement, all of cell K exchanged at a single rate. Cells from small cats are smaller and have larger surface/volume ratios than cells from large cats. The larger surface/volume ratio results in larger flux values. JK increases in an approximately linear manner as the external K concentration is increased twentyfold, from 2.5 to 50 mM, at constant intracellular K concentration. The permeability for K ions, PK, calculated from the influx and membrane potential, remains very nearly constant over this range of external K concentrations. JK is not affected by replacement of O2 by N2, or by stimulated contractions at 60 per minute, but K influx decreases markedly in 10-5 M and 10-8 M ouabain.
Type of Medium:
Online Resource
ISSN:
1540-7748
,
0022-1295
DOI:
10.1085/jgp.48.5.933
Language:
English
Publisher:
Rockefeller University Press
Publication Date:
1965
detail.hit.zdb_id:
1477246-2
SSG:
12
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