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  • Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)  (77)
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  • Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)  (77)
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  • 1
    Online Resource
    Online Resource
    Isolation, selection and evaluation of α-glucosidase inhibitory activity from endophytic Streptomyces sp. isolated from Citrus myrtifolia cultivar in Hoa Binh, Vietnam
    Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications) ; 2022
    In:  Vietnam Journal of Biotechnology Vol. 20, No. 4 ( 2022-12-28), p. 693-704
    Details
    In: Vietnam Journal of Biotechnology, Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications), Vol. 20, No. 4 ( 2022-12-28), p. 693-704
    Abstract: Cao Phong orange (Citrus sinensis Lour) was grown in Cao Phong district, Hoa Binh province. Citrus sinensis is Vietnam’s most valued commercial fruit. In this study, 30 microorganim strains were isolated from the samples of root, stem, and leaf of Cao Phong orange. The ratio of endophytic actinomycetes was found in different parts of the plant: root, stem, and leaf was 37%, 40%, and 23%, respectively. The isolating HBC6-2 was selected because of its high output of α-glucosidase inhibitors from 6 different strains. Morphological, physiological, and biochemical characterization showed that HBC6-2 strain belongs to the Streptomyces sp. The 16S rRNA sequence of HBC6-2 indicated 99% identity to the corresponding sequence of Streptomyces costaricanus, and was registered on GenBank with the code MT 453944.1. Streptomyces costaricanus EBL.HB6 was able to produce melanin yelow pigment, and its aerial and substrate mycelia have brown and yellow-grey pigment on ISP2, ISP3, ISP4, and ISP5 cultivating medium, respectively. The optimal pH range was from 5-10 and temperature from 15-40°C and exhibited salt tolerance up to 3% and utilized the carbon sources such as fructose, xylose, arabinose, cellulose, and rhamnose. In the following investigation, Streptomyces costaricanus EBL.HB6 displayed the highest α-glucosidase inhibitory activity by 68.98% among Streptomyces sp. strains
    Type of Medium: Online Resource
    ISSN: 2815-5912 , 2815-5955
    URL: Article
    DOI: 10.15625/1811-4989/17172
    Language: Unknown
    Publisher: Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
    Publication Date: 2022
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  • 2
    Online Resource
    Online Resource
    Optic bionanospherical probe from Gd\(_2\)O\(_3\): Yb, Er upconverting nanosphere and mAb^CD133 antibody for precise imaging label of cancer stem cell NTERA-2
    Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications) ; 2023
    In:  Communications in Physics Vol. 33, No. 3 ( 2023-08-09), p. 251-
    Details
    In: Communications in Physics, Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications), Vol. 33, No. 3 ( 2023-08-09), p. 251-
    Abstract: Rare earth photonic nanomaterials are increasingly prominently applied in various fields of biomedicine. Currently, there is greater focus on the investigation to control the size and shape of nanomaterials, including the nanospherical form, which allows for precise labeling by only one nanoparticle. This paper demonstrates, for the first time, the construction of a biological nanospherical probe (BNSP) Gd2O3: Yb3+, Er3+/Silica/NH/mAb^CD133 for diagnostic labeling of cancer stem cells (CSCs) NTERA-2. The BNSP was constructed using highly monodisperse spheres with around 200nm uniform size of Gd2O3: 7.6% Yb3+, 1.6% Er3+. They were functionalized by an amine group-contained shell coating and conjugated with CD133 monoclonal antibody. The functionalized nanosphere Gd2O3: Yb, Er/silica/NH2 showed strong upconversion luminescence in red color upon laser excitation in the near-infrared region at 975 nm. The Gd2O3: Yb3+, Er3+/silica/NH2 was carefully implemented to conjugate mAb^CD133 via a linker, glutaraldehyde, to obtain the predictable probe Gd2O3: Yb3+, Er3+/Silica/NH/mAb^CD133. Then, this BNSP was tested in vitro for its capacity to label NTERA-2 cancer stem cells. The efficient labeling based on the fluorescent immunoassay method was detected by incorporating a nanophotometer, Field Energy Scan Electron Microscopy (FESEM), and precisely determined by fluorescent microscopy. The study shows that the BNSP is highly efficient with targeting capacity and specificity in the labeling of cancer stem cells. These advanced results open up promising avenues for the development of precise imaging diagnostics in cancer cellular biomedicine, and beyond.
    Type of Medium: Online Resource
    ISSN: 2815-5947 , 0868-3166
    URL: Issue
    URL: Article
    DOI: 10.15625/0868-3166/2023Vol33No3
    DOI: 10.15625/0868-3166/18226
    Language: Unknown
    Publisher: Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
    Publication Date: 2023
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    Online Resource
  • 3
    Online Resource
    Online Resource
    Production of nanoliposomes with piperine from black pepper (Piper nigrum) and its improved growth inhibitory activity on colorectal cancer cells
    Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications) ; 2021
    In:  Vietnam Journal of Biotechnology Vol. 18, No. 4 ( 2021-05-24), p. 671-678
    Details
    In: Vietnam Journal of Biotechnology, Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications), Vol. 18, No. 4 ( 2021-05-24), p. 671-678
    Abstract: Black pepper (Piper nigrum) is an autoicous and decorous vine cultivated in many local regions of Gia Lai. Black pepper is one of the most commonly consumed spices, and its pungency is due to the presence of alkaloids, such as piperine. This compound represents diverse biological activities, including anti-inflammatory, anticancer, antiviral, anti-larvicidal, pesticide, anti-alzheimer’s activities, etc. However, due to its poor solubility as well as its toxic effects at high use concentration, piperine is still in limit of pharmaceutical applications. In this study, we have used black pepper seed collected at Chu Se - Gia Lai to extract piperine. The compound extracted efficiency was approximately 18% with 96.7% of purity. Based on the obtained pure piperine, the hybrid nanopiperine-CD133 monoclonal antibody (mAb^CD133) complexes were fabricated with the nanoparticle size of about 170 nm, the polydispersity index (PDI) of 0.23 and the zeta potential of -9.4 mV. The nanocomplex was subjected for growth inhibitory activities against cancer colorectal cells (HT-29 cell line). The results showed that the nanopiperine-mAb^CD133 complex exhibited significant in vitro growth inhibition HT-29 colorectal cancer cells (46.56 ± 2.78%), while the viability of healthy cells remained unaffected (17.77 ± 0.82 %). The nanocomplex could also label 12.17% of HT-29 cells, which was rather higher than 3.83% from mAb^CD133 conjugated phycoerythrin (PE) as positive control. The fabricated nanopiperine-mAb^CD133 complex has proved the enhanced cytotoxic activities against colorectal cancerous cells as well as promising biopharmaceutical potency.
    Type of Medium: Online Resource
    ISSN: 1811-4989 , 1811-4989
    URL: Article
    DOI: 10.15625/1811-4989/18/4/16086
    Language: Unknown
    Publisher: Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
    Publication Date: 2021
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  • 4
    Online Resource
    Online Resource
    ACUTE AND SUBACUTE TOXIC STUDY ON MICE OF GLIPIZIDE SYNTHESIZED IN VIET NAM
    Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications) ; 2019
    In:  Vietnam Journal of Science and Technology Vol. 57, No. 1 ( 2019-02-18), p. 15-
    Details
    In: Vietnam Journal of Science and Technology, Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications), Vol. 57, No. 1 ( 2019-02-18), p. 15-
    Abstract: Glipizide is a second generation of sulfonylurea with promising hypoglycemic activity. It acts by stimulating the release of insulin from β-cells of pancreas. Glipizide is absorbed rapidly, uniformly with good mean oral bioavailability. It offers several advantages such as swift and short action, high potency and also does not accumulate in plasma on repeated oral administration. In this paper we report the acute and subacute toxicity of glipizide on BALB/c albino mice. The results showed the safety of our synthesized products.
    Type of Medium: Online Resource
    ISSN: 2525-2518 , 2525-2518
    URL: Article
    DOI: 10.15625/2525-2518/57/1/12274
    Language: Unknown
    Publisher: Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
    Publication Date: 2019
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  • 5
    Online Resource
    Online Resource
    Holocene sedimentary facies in the incised valley of Ma River Delta, Vietnam
    Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications) ; 2023
    In:  Vietnam Journal of Earth Sciences ( 2023-09-18)
    Details
    In: Vietnam Journal of Earth Sciences, Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications), ( 2023-09-18)
    Abstract: Holocene sediment facies in the incised valley of the Ma River Delta were clarified by using analysis of LKTH6 core (30 m depth) such as sedimentary structure analysis, grain-sized, micro-paleontological (foraminifera, spore and pollen, and diatom), clay minerals characteristics, and Radiocarbon dating (14C). Ten sedimentary facies were identified, including (1) flood plain silty clay facies, (2) Salt marsh clayey silt facies, (3) Tidal flat sandy silty clay facies, (4) Tidal creek and tidal branch silty clayey sand facies, (5) Bay silty clay facies, (6) Prodelta silty clay facies, (7) Delta front silty sand facies, (8) Mouth bar sand facies, (9) Point bar silty sand faces, and (10) Alluvial plain silty clay facies. The sea level change after the last glacial was recorded by sediment facies and radiocarbon dating (14C). It showed that the Thanh Hoa coastal area drowned around 9500 yr. B.P. by transgression. At 9200 yr. B.P. initial marine flooding surface, tidal flats were formed in the coastal estuary area. During the period of 9200 -8300 yr. B.P., due to rapid sea level rise, the study area became an estuarine around 7600 yr. B.P., the sea level rose slowly, leading to the sea level rise rate being smaller than the sedimentary accumulation rate, and the delta was formed.
    Type of Medium: Online Resource
    ISSN: 2615-9783
    URL: Article
    DOI: 10.15625/2615-9783/18923
    Language: Unknown
    Publisher: Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
    Publication Date: 2023
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  • 6
    Online Resource
    Online Resource
    Conjugation of nanomaterials containing rare-earth ion Tb3+ with CD133 monoclonal antibody and its potentials for labeling colon cancer cells (HT-29)
    Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications) ; 2020
    In:  Vietnam Journal of Biotechnology Vol. 17, No. 3 ( 2020-11-28), p. 427-433
    Details
    In: Vietnam Journal of Biotechnology, Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications), Vol. 17, No. 3 ( 2020-11-28), p. 427-433
    Abstract: Nanotechnology is the key technology that brings many important applications in biomedical research.Nanolantanites present high stability, easy fabrication and functionalization. Tb3+ ion-containing nanomaterial, a specific type of nanolantanites, possess great prospects. In addition, cancer stem cells (CSCs) are directlyrelated to drug resistance, metastasis, recurrent cancer, etc. Therefore, CSCs are considered as the target forcancer researching and for discovery of more effective therapies. CD133, a trans-membrane glycoprotein, isone of the typical markers that are found to appear very commonly on the surface of many types of CSCs. Inthis study, CD133 monoclonal antibody (MAb) was cojugated with nanomaterials containing Tb3+. Thecoupling between fluorescented nanomaterials containing Tb3+ ions and CD133 MAb was then incubated withhuman colon cancer cells (HT-29) to evaluate its ability to label CSCs in vitro. The results showed thatnanorods containing rare-earth based Tb3+ ions which were fabricated by hydrothermal method, present thelength of about 300 - 800 nm and the diameter in range of 40 - 50 nm. The Tb3+ nanoparticals also havehexagonal structure of terbium phosphate monohydrate and green illuminant. Tb3+ nanorods were also furthersurface silica coated and amino-silane functionalized. This nanostructure was successfully combined withmonoclonal antibodies against CD133 which labelled the surface marker of HT-29 human colon cancer cells.As a result, the combination of CD133+TbPO4@Silica-NH2 (functionalized surface) showed strongerluminescence than the CD133+TbPO4 unfunctionalized combination.
    Type of Medium: Online Resource
    ISSN: 1811-4989 , 1811-4989
    URL: Article
    DOI: 10.15625/1811-4989/17/3/14620
    Language: Unknown
    Publisher: Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
    Publication Date: 2020
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  • 7
    Online Resource
    Online Resource
    Study of the morphology of the low-latitude D region ionosphere using the method of tweeks observed at Buon Ma Thuot, Dak Lak
    Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications) ; 2016
    In:  VIETNAM JOURNAL OF EARTH SCIENCES Vol. 38, No. 4 ( 2016-10-20)
    Details
    In: VIETNAM JOURNAL OF EARTH SCIENCES, Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications), Vol. 38, No. 4 ( 2016-10-20)
    Type of Medium: Online Resource
    ISSN: 0866-7187 , 0866-7187
    URL: Article
    DOI: 10.15625/0866-7187/38/4/8794
    Language: Unknown
    Publisher: Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
    Publication Date: 2016
    SSG: 6,25
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  • 8
    Online Resource
    Online Resource
    BEHAVIOUR OF PASSIVE FILMS ON STAINLESS STEEL EXPOSED IN VARIOUS CORROSIVE CONDITIONS
    Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications) ; 2022
    In:  Vietnam Journal of Science and Technology Vol. 59, No. 6A ( 2022-03-11), p. 135-146
    Details
    In: Vietnam Journal of Science and Technology, Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications), Vol. 59, No. 6A ( 2022-03-11), p. 135-146
    Abstract: Corrosion behavior of different steel grades such as 304 and 445NF types with passive films formed under various corrosive environments was examined according to ASTM G61-86 (2014). The distinctive susceptibility of the steel grades to local corrosion in chloride solutions was also discussed. A distinction in corrosion of these steel grades was defined by different austenitic and ferritic natures as well as their elemental compositions. Besides, a corrosion survey of these materials was also conducted for constructions exposed in various atmospheric natural areas ranging from benign rural to aggressive marine conditions. Damages were detected at surfaces of popularly used constructions made of Type 304 stainless steel, where more severe deterioration was observed in the area with higher airborne salinity; examination on Type 445 stainless steel in the same environmental conditions gave results of less severe deterioration and milder damages on surfaces in comparison to Type 304. Different states of passive films also affect the result of the experiments. Corrosion appearance and corrosion products examined by visual inspection and EPMA techniques for steel surfaces showed the influence of airborne salinity on the degree of damage. Corrosion of the steel surfaces was attributed to the combined effect of atmospheric airborne salinity and high time-of-wetness (TOW).  
    Type of Medium: Online Resource
    ISSN: 2525-2518 , 2525-2518
    URL: Article
    DOI: 10.15625/2525-2518/16242
    Language: Unknown
    Publisher: Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
    Publication Date: 2022
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  • 9
    Online Resource
    Online Resource
    Corrosion of stainless steel water storage tanks exposed in coastal atmospheric conditions
    Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications) ; 2018
    In:  Vietnam Journal of Science and Technology Vol. 56, No. 3B ( 2018-09-13), p. 1-
    Details
    In: Vietnam Journal of Science and Technology, Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications), Vol. 56, No. 3B ( 2018-09-13), p. 1-
    Abstract: Results of corrosion survey for stainless steel tanks used in water storage at various coastal areas are presented. Corrosion damages were revealed at both the outer and inner surfaces of tanks made of 304 and 201 steel grades. Corrosion deterioration was more severely observed for the atmospheric areas with higher airborne salinity and time of wetness.  Corrosion products examined by visual inspection and SEM-EDX technique show relatively distinctive characteristics for outer and inner surfaces which are attributed to different mechanisms of corrosion initiated by various corrosive agents in the atmosphere. Atmospheric chlorides from airborne sources are considered the main reason for causing corrosion of 304 and 201 steel grade water tanks.
    Type of Medium: Online Resource
    ISSN: 2525-2518 , 2525-2518
    URL: Article
    DOI: 10.15625/2525-2518/56/3B/12812
    Language: Unknown
    Publisher: Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
    Publication Date: 2018
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  • 10
    Online Resource
    Online Resource
    Effects of metal nanoparticles of iron, copper and cobalt on the growth of nitrogen-fixing bacterium Sinorhizobium fredii T14 and nodulation in soybean roots
    Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications) ; 2022
    In:  Vietnam Journal of Biotechnology Vol. 19, No. 4 ( 2022-05-03), p. 725-733
    Details
    In: Vietnam Journal of Biotechnology, Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications), Vol. 19, No. 4 ( 2022-05-03), p. 725-733
    Abstract: Soybean is a high valuable crop of Vietnam and many other countries. The ability of soybean plants in nitrogen fixation and soil improvement is attributed to their symbiosis with different rhizobia in the root nodules. It has been well documented that members of genus Rhizobium are the most effective in nodulation and nitrogen fixation in legumes. Recently, in oder to minimize undesired accumulation of agro-chemicals and metal salts in soil, nanotechnology products have been intensively studied and applied as nanofertilizers. In this report, the effect of nanoparticles of iron, cobalt and copper on the in vitro growth of nitrogen fixing bacterium Sinorhizobium fredii T14 and nodulation in the root of soybean DT26 was studied. In the cultures of S. fredii T14, nano Fe at the final concentrations of 2, 5, 10, 25 and 50 ppm did not affect the growth, but the latter was reduced of 20, 35 and 46% at 100, 250 and 500 ppm, respectively. No growth inhibition was observed at nano Co concentrations below 10 ppm, while it was reduced of 73% at 500 ppm. Nano Cu seemed to have significant adverse effect on S. fredii T14, showing growth inhibition of 23, 68 and 100% at the concentrations of 5, 25 ppm and 50 ppm, respectively. The production of extracellular polysaccharide by S. fredii T14 was not affected at the concentrations of nano Fe and Co below 250 ppm, while drastic decrease occurred at the presence of nano Cu. Laboratory experiments showed that nanoparticles of all three studied metals at extremely low concentration of 2 ppm significantly increased the number of effective nodules in the roots of soybean DT26 and enhanced the plant growth. 
    Type of Medium: Online Resource
    ISSN: 1811-4989 , 1811-4989
    URL: Article
    DOI: 10.15625/1811-4989/17107
    Language: Unknown
    Publisher: Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
    Publication Date: 2022
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