In:
PLOS ONE, Public Library of Science (PLoS), Vol. 16, No. 11 ( 2021-11-22), p. e0259725-
Abstract:
The bacterium Pseudomonas anguilliseptica has in recent years emerged as a serious threat to production of lumpfish in Norway. Little is known about the population structure of this bacterium despite its association with disease in a wide range of different fish species throughout the world. The phylogenetic relationships between 53 isolates, primarily derived from diseased lumpfish, but including a number of reference strains from diverse geographical origins and fish species, were reconstructed by Multi-Locus Sequence Analysis (MLSA) using nine housekeeping genes ( rpoB , atpD , gyrB , rpoD , ileS , aroE , carA , glnS and recA ). MLSA revealed a high degree of relatedness between the studied isolates, altough the seven genotypes identified formed three main phylogenetic lineages. While four genotypes were identified amongst Norwegian lumpfish isolates, a single genotype dominated, irrespective of geographic origin. This suggests the existence of a dominant genotype associated with disease in production of lumpfish in Norwegian aquaculture. Elucidation of the population structure of the bacterium has provided valuable information for potential future vaccine development.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0259725
DOI:
10.1371/journal.pone.0259725.g001
DOI:
10.1371/journal.pone.0259725.g002
DOI:
10.1371/journal.pone.0259725.t001
DOI:
10.1371/journal.pone.0259725.t002
DOI:
10.1371/journal.pone.0259725.t003
DOI:
10.1371/journal.pone.0259725.t004
DOI:
10.1371/journal.pone.0259725.s001
DOI:
10.1371/journal.pone.0259725.s002
DOI:
10.1371/journal.pone.0259725.s003
DOI:
10.1371/journal.pone.0259725.s004
DOI:
10.1371/journal.pone.0259725.s005
DOI:
10.1371/journal.pone.0259725.s006
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2021
detail.hit.zdb_id:
2267670-3
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