In:
PLOS ONE, Public Library of Science (PLoS), Vol. 17, No. 6 ( 2022-6-6), p. e0269594-
Abstract:
Chewing well is essential for successful diet therapy and control of blood glucose level in patients with diabetes. In addition, long-term hyperglycemia is a risk factor for microvascular complications, which are the main cause of morbidity and mortality in these patients. Hence, it is plausible that masticatory disorder may be relevant to diabetic microvascular complications which is caused by long-term hyperglycemia. The aim of this study was to investigate whether masticatory disorders are relevant to diabetic microvascular complications. Methods This cross-sectional study included 172 patients with type 2 diabetes who underwent educational hospitalization in the Department of Endocrinology and Diabetic Medicine, Hiroshima University Hospital, from April 2016 to March 2020. Masticatory efficiency was determined quantitatively by using the GLUCO SENSOR GS-Ⅱ. Multivariable linear regression models were constructed to examine which factors were related to masticatory efficiency. Statistical significance was defined as a two-sided p value of 〈 0.05. Results According to the bivariable analysis, masticatory efficiency was significantly correlated with duration of diabetes ( p = 0. 049), number of remaining teeth ( p 〈 0.0001), the number of moving teeth ( p = 0.007) and condition of diabetic neuropathy ( p 〈 0.0001). Moreover, the number of remaining teeth ( p 〈 0.0001) and diabetic neuropathy ( p = 0.007) remained significantly correlated with masticatory efficiency in the multivariable analysis. Conclusions For the first time, we demonstrated that patients with type 2 diabetes who developed diabetic neuropathy had significantly reduced masticatory efficiency. Effective mastication is an important factor in successful diet therapy for diabetes. To prevent the progression of diabetic complications, especially in patients with diabetic neuropathy, it may be necessary to combine individualized therapies from dentists and nutritionists with consideration for the level of masticatory dysfunction.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0269594
DOI:
10.1371/journal.pone.0269594.g001
DOI:
10.1371/journal.pone.0269594.g002
DOI:
10.1371/journal.pone.0269594.g003
DOI:
10.1371/journal.pone.0269594.t001
DOI:
10.1371/journal.pone.0269594.t002
DOI:
10.1371/journal.pone.0269594.t003
DOI:
10.1371/journal.pone.0269594.s001
DOI:
10.1371/journal.pone.0269594.s002
DOI:
10.1371/journal.pone.0269594.s003
DOI:
10.1371/journal.pone.0269594.r001
DOI:
10.1371/journal.pone.0269594.r002
DOI:
10.1371/journal.pone.0269594.r003
DOI:
10.1371/journal.pone.0269594.r004
DOI:
10.1371/journal.pone.0269594.r005
DOI:
10.1371/journal.pone.0269594.r006
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2022
detail.hit.zdb_id:
2267670-3
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