In:
PLOS Neglected Tropical Diseases, Public Library of Science (PLoS), Vol. 16, No. 4 ( 2022-4-29), p. e0010369-
Abstract:
Scrub typhus is the most common endemic vector-borne disease in Taiwan. We identified a total of 4,857 laboratory-confirmed cases during 2006–2016 with hyperendemic foci on offshore islands, including Penghu (778 cases, 16.0%) and Kinmen (716 cases, 14.7%), and eastern Taiwan, including Taitung (628 cases, 12.9%) and Hualien (508 cases, 10.5%). Scrub typhus cases occur year-round throughout Taiwan, with a summer peak in June and July. A total of 545 O . tsutsugamushi isolates were successfully obtained from patients infected in diverse geographic areas, including Taiwan and three offshore islands, and the complete open reading frame of the 56 kDa type-specific antigen gene ( tsa56 ) sequence of these isolates was examined. High phylogenetic diversity was found in these isolates, which could be grouped into 36 distinct sequence types. Most isolates belonged to the Karp (49.9%; 272/545), followed by the TW-22 (17.8%; 97/454) and Kawasaki (14.7%; 80/545) genotypes. In conclusion, our data indicate the widespread presence of tsa56 genotypes closely related to Thailand and Korean strains and the presence of the unique endemic strains TW-12, TW-22, TW-29, and TW-36 in Taiwan.
Type of Medium:
Online Resource
ISSN:
1935-2735
DOI:
10.1371/journal.pntd.0010369
DOI:
10.1371/journal.pntd.0010369.g001
DOI:
10.1371/journal.pntd.0010369.g002
DOI:
10.1371/journal.pntd.0010369.g003
DOI:
10.1371/journal.pntd.0010369.g004
DOI:
10.1371/journal.pntd.0010369.g005
DOI:
10.1371/journal.pntd.0010369.t001
DOI:
10.1371/journal.pntd.0010369.t002
DOI:
10.1371/journal.pntd.0010369.t003
DOI:
10.1371/journal.pntd.0010369.t004
DOI:
10.1371/journal.pntd.0010369.s001
DOI:
10.1371/journal.pntd.0010369.s002
DOI:
10.1371/journal.pntd.0010369.s003
DOI:
10.1371/journal.pntd.0010369.r001
DOI:
10.1371/journal.pntd.0010369.r002
DOI:
10.1371/journal.pntd.0010369.r003
DOI:
10.1371/journal.pntd.0010369.r004
DOI:
10.1371/journal.pntd.0010369.r005
DOI:
10.1371/journal.pntd.0010369.r006
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2022
detail.hit.zdb_id:
2429704-5
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