In:
Proceedings of the National Academy of Sciences, Proceedings of the National Academy of Sciences, Vol. 84, No. 3 ( 1987-02), p. 643-647
Abstract:
Wheat seedlings germinating in the presence of the systemic fungicide fenpropimorph accumulate 9β,19-cyclopropylsterols (95% of total sterols) in place of Δ 5 -sterols, which are normally produced in these plants. Adult females of the phytophagous insect Locusta migratoria show a dramatic decrease in their cholesterol content when reared on fenpropimorph-treated wheat. These females lay eggs with the ecdysteroid concentration reduced by up to 80% as compared to controls. Injection of fenpropimorph to the insects or feeding them on wheat coated with the fungicide (normal sterol composition) does not affect their sterol or ecdysteroid profiles; addition of cholesterol to fenpropimorph-treated wheat prior to feeding restores normal ecdysteroid titers in the insects. The severe reduction of the ecdysteroid content in eggs laid by females reared on fenpropimorph-treated wheat is associated with a series of developmental arrests and/or abnormalities. The results show that the dietary 9β,19-cyclopropylsterols cannot be used by Locusta in place of Δ 5 -sterols for ecdysteroid biosynthesis. They suggest that the selective inhibition of specific enzymes in the sterol biosynthetic pathway of the plants can be used as a strategy to control insect development.
Type of Medium:
Online Resource
ISSN:
0027-8424
,
1091-6490
DOI:
10.1073/pnas.84.3.643
Language:
English
Publisher:
Proceedings of the National Academy of Sciences
Publication Date:
1987
detail.hit.zdb_id:
209104-5
detail.hit.zdb_id:
1461794-8
SSG:
11
SSG:
12
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