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  • PAGEPress Publications  (5)
  • 1
    Online Resource
    Online Resource
    Urine diacetylated spermine might be a nonspecific tumor marker in canine neoplasia
    PAGEPress Publications ; 2011
    In:  Veterinary Science Development Vol. 1, No. 1 ( 2011-12-12), p. 16-
    Details
    In: Veterinary Science Development, PAGEPress Publications, Vol. 1, No. 1 ( 2011-12-12), p. 16-
    Abstract: Diacetylated spermine, a polyamine, is clinically used as a tumor marker in human medicine. The purpose of this study was to evaluate the usefulness of diacetylated spermine as a nonspecific tumor marker in dogs. One hundred six dogs were randomly selected and divided into 4 groups (cancer-bearing, n=23; control, n=44; young, n=24; inflammatory, n=15). Urine samples were collected to measure diacetylated spermine and creatinine levels. The diacetylated spermine concentration was determined by enzyme-linked immunoassay, standardized by creatinine concentration. The urine diacetylated spermine concentration was markedly significant elevated in cancer-bearing dogs, as compared to that in control dogs (P=0.0081). Whilst the urine diacetylated spermine level in cancer-bearing group was not markedly different from that in the young group, there was significant different between levels in the control and young groups (P=0.019). No significant difference was observed between the inflammatory and cancer-bearing groups. It is suggested that urine diacetylated spermineis a useful tumor marker in dogs over 2 years of age.
    Type of Medium: Online Resource
    ISSN: 2038-9701 , 2038-9698
    URL: Article
    DOI: 10.4081/vsd.2011.3771
    Language: Unknown
    Publisher: PAGEPress Publications
    Publication Date: 2011
    detail.hit.zdb_id: 2627484-X
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  • 2
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    Two-hole extracapsular technique for the repair of canine cranial cruciate ligament rupture in thirty-eight dogs
    PAGEPress Publications ; 2014
    In:  Veterinary Science Development Vol. 4, No. 2 ( 2014-05-08)
    Details
    In: Veterinary Science Development, PAGEPress Publications, Vol. 4, No. 2 ( 2014-05-08)
    Abstract: Extracapsular technique with lateral fabellar suture (LFS) is one of the commonest surgical techniques for canine cranial cruciate ligament (CRCL) rupture. Among LFS methods, parallel double holes in the tibia are the most effective for the repair of canine stifle joint. The aim of this study was to evaluate the effectiveness of two-hole LFS for canine CRCL rupture. We retrospectively evaluated the outcome of canine CRCL rupture treated with two-hole LFS technique performed by two surgeons from October 2011 to September 2013. Breeds included Beagle (n=5), Yorkshire terrier (n=5), German shepherd (n=4), and so on. Mean body weight was 14.0±11.6 kg ( & gt;10 kg: n=16, & lt;10 kg: n=22). Body condition score (5 scales) was as follows: 1 (n=0), 2 (n=1), 3 (n=18), 4 (n=18), and 5 (n=1). There were 18 males [neutered (n=11)] and 20 females [spayed (n=12)]. Mean age was 83.4±44.8 months ( & gt;12 months: n=35, & lt;12 months: n=3). The type of rupture was partial (n=17) and complete (n=21). The affected site was right (n=20), left (n=18), and bilateral (n=4). Rehabilitation after operation was needed in 8 cases. There were 12 cases of previous medial patellar luxation operation, and 6 cases of opposite site CRCL surgery. Start of weight bearing and resolution of extension function was on day 1 (n=30), day 2 (n=0), and after day 2 (n=8). There was no evidence of surgical site infection/inflammation in any cases. The results of this study showed that two-hole LFS is an easy and effective technique for the repair of canine CRCL.
    Type of Medium: Online Resource
    ISSN: 2038-9701 , 2038-9698
    URL: Article
    DOI: 10.4081/vsd.2014.5284
    Language: Unknown
    Publisher: PAGEPress Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2627484-X
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  • 3
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    Clinical and laboratory features of 48 feline hyperthyroidism cases in Japan
    PAGEPress Publications ; 2014
    In:  Veterinary Science Development Vol. 4, No. 1 ( 2014-02-07)
    Details
    In: Veterinary Science Development, PAGEPress Publications, Vol. 4, No. 1 ( 2014-02-07)
    Abstract: Feline hyperthyroidism (HT) is a common endocrine disorder worldwide, but clinical and laboratory features might vary geographically. The aim of this retrospective study was to evaluate feline HT in Japan, and compare results to those of previous study for feline HT. We evaluated 48 feline HT cases clinical and laboratory features. Surprisingly, the youngest patient was 32 months of age (2 year 9 months). There was no significant difference among the study subjects in sex, but frequency of spayed/castrated cats was high (85.4%). Median age was 186 months (32-272 months). 91.3% (n=42) of subjects were over 10 years of age, and 8.7% (n=4) were under 10 years of age. Clinical symptoms included vomiting, 56.3% (n=27); diarrhea, 2.1% (n=1); hyperactivity, 12.5% (n=6); emaciation, 41.7% (n=20); polyuria and polydipsia, 22.9% (n=11); chronic weight loss, 60.4% (n=29); and palpated enlarged thyroid, 2.1% (n=1). Concurrent findings included chronic kidney disease, 20.8% (n=10); congestive heart failure, 20.8% (n=10); tachycardia (over 240 beats/min), 18.8% (n=9); gallop rhythm, 31.3% (n=15); neurological disorders such as hind-limb paralysis, 14.6% (n=7); cystitis, 8.7% (n=4); gingivitis, 4.2% (n=2); diabetes mellitus, 4.2% (n=2); and arterial thromboembolism, 6.3% (n=3). In addition, laboratory features (complete blood counts and biochemistry) differed from those of previous reports in certain respects. Our results show that it might be important for practitioners to comprehend epidemiologic differences regarding feline HT worldwide.
    Type of Medium: Online Resource
    ISSN: 2038-9701 , 2038-9698
    URL: Article
    DOI: 10.4081/vsd.2014.5080
    Language: Unknown
    Publisher: PAGEPress Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2627484-X
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  • 4
    Online Resource
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    Histamine concentration is involved in canine valvular disease
    PAGEPress Publications ; 2014
    In:  Veterinary Science Development Vol. 4, No. 2 ( 2014-05-08)
    Details
    In: Veterinary Science Development, PAGEPress Publications, Vol. 4, No. 2 ( 2014-05-08)
    Abstract: It has been known since many years that there are histamine receptors (H) in the heart. Histamines display chronotropic and inotropic activity, cardiovascular diseases, and are thought to be a systemic inflammatory disease. During heart failure, the histamine concentration is elevated. In addition, H2 blockers prolonged the survival period for human patients with heart failure. The aim of this study was to evaluate whether blood concentration of histamine is associated with canine valvular disease (CVD). The histamine concentrations of dogs with CVD are significantly higher than those of healthy dogs. The histamine concentration gradually increases during CVD and is highly correlated with the grade of heart murmur. In conclusion, the histamine concentration was higher in the population of dogs with CVD compared with the healthy controls. Although the etiopathogenesis of CVD is complex and incompletely understood, it likely involves histamine. Ultimately additional studies are required to determine whether histamine blockers might be useful for the management of dogs with cardiac valvular disease.
    Type of Medium: Online Resource
    ISSN: 2038-9701 , 2038-9698
    URL: Article
    DOI: 10.4081/vsd.2014.5123
    Language: Unknown
    Publisher: PAGEPress Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2627484-X
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  • 5
    Online Resource
    Online Resource
    Corrective surgery for canine patellar luxation in 75 cases (107 limbs): landmark for block recession
    PAGEPress Publications ; 2014
    In:  Veterinary Science Development Vol. 4, No. 2 ( 2014-05-08)
    Details
    In: Veterinary Science Development, PAGEPress Publications, Vol. 4, No. 2 ( 2014-05-08)
    Abstract: Canine medial patellar luxation (MPL) is a very common orthopedic disease in small animals. Because the pathophysiology of this disease involves various pathways, the surgical techniques and results vary according to the veterinarian. Further, the landmark for block recession is not completely clear. We retrospectively evaluated 75 dogs (107 limbs) with MPL in whom our landmark for block recession was used from July 2008 to May 2013. Information regarding the breed, age, sex, body weight, body condition score (BCS), lateral 〈 em 〉 vs 〈 /em 〉 bilateral, pre-operative grading, surgical techniques, removal of implants, concomitance with anterior cruciate ligament (ACL) rupture, re-luxation, re-operation, and rehabilitation was obtained from the medical records. The breeds were as follows: Chihuahua (n=23), Pomeranian (n=12), Yorkshire Terrier (n=9), and so on. The study group consisted of 33 males (castrated n=13) and 42 females (spayed n=21). The median age was 53.3±35.9 months (32-146 months); 13 cases were less than 12 months of age (17.3%). The pre-surgical BCSs were as follows: 1 (n=0), 2 (n=20), 3 (n=24), 4 (n=24) and 5 (n=7). The body weight was 4.51±3.48 kg (1.34-23.0 kg); 71 cases (94.7%) were less than 10 kg. The MPL grades (each limb) were G1 (n=1), G2 (n=18), G3 (n=78), and G4 (n=10); 32 cases were bilateral and 43 cases were unilateral (right n=27; left n=16). The specific surgical procedure (distal femoral osteotomy) was 3 stifles in Chihuahuas. Concurrent with ACL rupture was 16/107 stifles (15.0%) corrected with the over-the-top method or the extracapsular method in Papillons (5/6), Chihuahuas (5/23), and so on. The occurrences of re-luxation and re-operation were 3 out of 107 stifles (2.8%) and 0%, respectively. In this retrospective study, we present a potentially good surgical landmark for block recession of MPL in dogs.
    Type of Medium: Online Resource
    ISSN: 2038-9701 , 2038-9698
    URL: Article
    DOI: 10.4081/vsd.2014.5251
    Language: Unknown
    Publisher: PAGEPress Publications
    Publication Date: 2014
    detail.hit.zdb_id: 2627484-X
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