In:
Pediatric Physical Therapy, Ovid Technologies (Wolters Kluwer Health), Vol. 30, No. 3 ( 2018-07), p. 209-215
Abstract:
To quantitatively describe passive lower extremity range of motion in participants with spinal muscular atrophy (SMA) types 2 and 3, and to establish preliminary thresholds to identify individuals at risk for performing poorly on disease-specific motor function outcome measures. Methods: Eighty participants with SMA types 2 and 3, enrolled in an international multicenter natural history study, were evaluated with lower extremity range of motion testing and the Hammersmith Functional Motor Scale-Expanded. Results: A hip extension joint angle of −7.5° or less for SMA type 2 and 0° or less for SMA type 3 identified diminished motor ability with good sensitivity. For knee extension, a joint angle of −9.0° or less for SMA type 2 or 0° or less for SMA type 3 was similarly sensitive. Conclusions: Minimal hip and knee joint contractures were associated with diminished motor ability. Clinical trial designs should consider the effect of contractures on motor function.
Type of Medium:
Online Resource
ISSN:
0898-5669
DOI:
10.1097/PEP.0000000000000515
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2018
detail.hit.zdb_id:
2071155-4
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